FI106211B - HCV-polypeptidi ja HCV:n määritysmenetelmä sekä vasta-ainekoostumukset - Google Patents
HCV-polypeptidi ja HCV:n määritysmenetelmä sekä vasta-ainekoostumukset Download PDFInfo
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- FI106211B FI106211B FI905591A FI905591A FI106211B FI 106211 B FI106211 B FI 106211B FI 905591 A FI905591 A FI 905591A FI 905591 A FI905591 A FI 905591A FI 106211 B FI106211 B FI 106211B
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Classifications
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
- C07K16/109—Hepatitis C virus; Hepatitis G virus
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32533889A | 1989-03-17 | 1989-03-17 | |
| US32533889 | 1989-03-17 | ||
| US34133489A | 1989-04-20 | 1989-04-20 | |
| US34133489 | 1989-04-20 | ||
| US35500289A | 1989-05-18 | 1989-05-18 | |
| US35500289 | 1989-05-18 | ||
| US9001348 | 1990-03-15 | ||
| PCT/US1990/001348 WO1990011089A1 (en) | 1989-03-17 | 1990-03-15 | Nanbv diagnostics and vaccines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI905591A0 FI905591A0 (fi) | 1990-11-12 |
| FI106211B true FI106211B (fi) | 2000-12-15 |
Family
ID=27406397
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI905591A FI106211B (fi) | 1989-03-17 | 1990-11-12 | HCV-polypeptidi ja HCV:n määritysmenetelmä sekä vasta-ainekoostumukset |
| FI20002014A FI107619B (fi) | 1989-03-17 | 2000-09-13 | HCV-polynukleotidit, niitä sisältävät välinepakkaukset ja niiden käyttö |
| FI20002013A FI107610B (fi) | 1989-03-17 | 2000-09-13 | HCV-fuusioproteiini |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20002014A FI107619B (fi) | 1989-03-17 | 2000-09-13 | HCV-polynukleotidit, niitä sisältävät välinepakkaukset ja niiden käyttö |
| FI20002013A FI107610B (fi) | 1989-03-17 | 2000-09-13 | HCV-fuusioproteiini |
Country Status (19)
| Country | Link |
|---|---|
| EP (3) | EP0388232B9 (hu) |
| JP (13) | JP2656995B2 (hu) |
| KR (2) | KR0185373B1 (hu) |
| AT (1) | ATE286979T1 (hu) |
| AU (3) | AU666767B2 (hu) |
| CA (1) | CA2012482C (hu) |
| DE (3) | DE388232T1 (hu) |
| DK (1) | DK0388232T3 (hu) |
| ES (2) | ES2020152T4 (hu) |
| FI (3) | FI106211B (hu) |
| GR (1) | GR910300016T1 (hu) |
| HU (3) | HUT54896A (hu) |
| IE (2) | IE20060608A1 (hu) |
| IL (1) | IL93764A (hu) |
| MY (1) | MY110260A (hu) |
| NO (1) | NO303941B1 (hu) |
| PT (1) | PT93480B (hu) |
| UA (1) | UA50829C2 (hu) |
| WO (1) | WO1990011089A1 (hu) |
Families Citing this family (181)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5523215A (en) * | 1985-03-28 | 1996-06-04 | Chiron Corporation | Enhanced purification and expression of insoluble recombinant proteins |
| US5712088A (en) * | 1987-11-18 | 1998-01-27 | Chiron Corporation | Methods for detecting Hepatitis C virus using polynucleotides specific for same |
| US6861212B1 (en) | 1987-11-18 | 2005-03-01 | Chiron Corporation | NANBV diagnostics and vaccines |
| US6171782B1 (en) | 1987-11-18 | 2001-01-09 | Chiron Corporation | Antibody compositions to HCV and uses thereof |
| US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
| US5714596A (en) * | 1987-11-18 | 1998-02-03 | Chiron Corporation | NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus |
| US5698390A (en) * | 1987-11-18 | 1997-12-16 | Chiron Corporation | Hepatitis C immunoassays |
| WO1990011089A1 (en) * | 1989-03-17 | 1990-10-04 | Chiron Corporation | Nanbv diagnostics and vaccines |
| US6027729A (en) * | 1989-04-20 | 2000-02-22 | Chiron Corporation | NANBV Diagnostics and vaccines |
| HUT59964A (en) * | 1989-05-18 | 1992-07-28 | Chiron Corp | Process for producing new nanbv diagnostica for determining hepatitis c virus |
| EP0416725A3 (en) * | 1989-07-14 | 1991-03-20 | Chugai Seiyaku Kabushiki Kaisha | Blood-borne non-a, non-b hepatitis specific protein, dna encoding it, and process for its production |
| CA2065287C (en) * | 1989-09-15 | 1999-12-21 | Tatsuo Miyamura | New hcv isolates |
| US5372928A (en) * | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
| US7166287B1 (en) | 1989-12-18 | 2007-01-23 | Glaxo Wellcome Inc. | Viral agent |
| DK298190A (da) * | 1989-12-18 | 1991-06-19 | Wellcome Found | Viralt middel |
| CA2032907C (en) * | 1989-12-22 | 2002-05-14 | Richard R. Lesniewski | Hepatitis c assay |
| US5308750A (en) * | 1989-12-22 | 1994-05-03 | Abbott Laboratories | Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same |
| EP0435229A1 (en) * | 1989-12-27 | 1991-07-03 | Sanwa Kagaku Kenkyusho Co., Ltd. | DNA of non-A, non-B hepatitis virus gene, its clone and use thereof |
| KR940000755B1 (ko) * | 1990-02-16 | 1994-01-29 | 유나이티드 바이오메디칼 인코오포레이티드 | Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드 |
| US5747239A (en) * | 1990-02-16 | 1998-05-05 | United Biomedical, Inc. | Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and preventions thereof as vaccines |
| US5582968A (en) * | 1990-02-16 | 1996-12-10 | United Biomedical, Inc. | Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis |
| US5106726A (en) * | 1990-02-16 | 1992-04-21 | United Biomedical, Inc. | Synthetic peptides specific for the detection of antibodies to HCV |
| RU2130969C1 (ru) † | 1990-04-04 | 1999-05-27 | Чирон Корпорейшн | Композиция для диагностики гепатита c человека (варианты), способ и набор для обнаружения антител к вирусу гепатита c человека |
| IE911130A1 (en) * | 1990-04-04 | 1991-10-09 | Protos | Hepatitis c protease inhibitors |
| IE911129A1 (en) | 1990-04-04 | 1991-10-09 | Chiron Corp | Hepatitis c virus protease |
| DE69132332T2 (de) * | 1990-04-06 | 2000-11-30 | Genelabs Tech Inc | Hepatitis c-virus-epitope |
| JP3050395B2 (ja) * | 1990-06-12 | 2000-06-12 | 国立感染症研究所長 | Ｃ型肝炎ウイルス抗原ポリペプチド、その産生方法および抗体の検出方法 |
| EP0461863A1 (en) * | 1990-06-12 | 1991-12-18 | Immuno Japan Inc. | Oligonucleotide primers, and their application for high-fidelity detection of non-A, non-B hepatitis virus |
| US5747339A (en) * | 1990-06-25 | 1998-05-05 | Research Foundation For Microbial Diseases Of Osaka | Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide |
| CA2045326A1 (en) * | 1990-06-25 | 1991-12-26 | Hiroto Okayama | Non-a, non-b, hepatitis virus particles |
| EP0933426A1 (en) * | 1990-06-25 | 1999-08-04 | The Research Foundation for Microbial Diseases of Osaka University | Non-a, non-b hepatitis virus genomic cdna fragments and antigen polypeptides |
| EP0551275B1 (en) * | 1990-06-30 | 1994-12-21 | Akzo Nobel N.V. | Non-a non-b sequences |
| EP0468657A3 (en) * | 1990-07-09 | 1992-02-05 | Tonen Corporation | Non-a non b hepatitis-specific antigen and its use in hepatitus diagnosis |
| ATE150086T1 (de) * | 1990-07-11 | 1997-03-15 | Shionogi & Co | Cdns-sequenz und detektion des hepatitis c-virus |
| CA2047792C (en) * | 1990-07-26 | 2002-07-02 | Chang Y. Wang | Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines |
| HUT69140A (en) * | 1990-08-10 | 1995-08-28 | Chiron Corp | Nanbv diagnostics: polynucleotides useful for screening for hepatitis c virus |
| JP3114731B2 (ja) * | 1990-08-14 | 2000-12-04 | 国立感染症研究所長 | Ｃ型肝炎ウイルス抗体検出用ペプチド抗原及びその使用方法 |
| US6172189B1 (en) * | 1990-08-24 | 2001-01-09 | Abbott Laboratories | Hepatitis C assay utilizing recombinant antigens |
| CA2049679C (en) * | 1990-08-24 | 2005-06-21 | Sushil G. Devare | Hepatitis c assay utilizing recombinant antigens |
| US7863008B2 (en) | 1990-08-25 | 2011-01-04 | Bioprocess Pty Ltd. | Method for detecting NANBV associated seroconversion |
| ES2273934T5 (es) * | 1990-08-25 | 2011-05-17 | Bioprocess Pty Ltd | Antígeno del virus de la hepatitis no a, no b, métodos diagnósticos y vacunas. |
| EP0479376B1 (en) * | 1990-10-05 | 1995-01-25 | Akzo Nobel N.V. | Peptides immunochemically reactive with antibodies directed against hepatitis Non-A, Non-B virus |
| ATE206717T1 (de) * | 1990-11-03 | 2001-10-15 | Dade Behring Marburg Gmbh | Hcv-spezifische peptide, mittel dazu und ihre verwendung |
| US5753430A (en) * | 1990-11-07 | 1998-05-19 | Abbott Laboratories | Monoclonal antibodies to hepatitis C virus and method for using same |
| ATE178096T1 (de) * | 1990-11-07 | 1999-04-15 | Abbott Lab | Monoklonale antikörper gegen den hepatitis c- virus und verfahren diese zu benutzen |
| CA2055149A1 (en) * | 1990-11-08 | 1992-05-09 | Hiroaki Okamoto | Non-a, non-b hepatitis virus related antigen, antibody, detection systems, polynucleotides and polypeptides |
| US6274148B1 (en) | 1990-11-08 | 2001-08-14 | Chiron Corporation | Hepatitis C virus asialoglycoproteins |
| JP2945759B2 (ja) | 1990-11-08 | 1999-09-06 | カイロン コーポレイション | Ｃ型肝炎ウイルスアシアロ糖タンパク質 |
| ES2218629T5 (es) * | 1990-11-08 | 2009-06-02 | Novartis Vaccines And Diagnostics, Inc. | Asialoglicoproteinas del virus de la hepatitis c. |
| SK286106B6 (sk) * | 1990-11-08 | 2008-03-05 | Novartis Vaccines & Diagnostics, Inc. | Spôsob vykonávania imunodiagnostickej skúšky na detekciu protilátky proti vírusu hepatitídy C |
| KR920703640A (ko) * | 1990-11-29 | 1992-12-18 | 테루카츄 아리마 | 비a비b형 간염 바이러스 항원 단백질 |
| DE69131316T2 (de) * | 1990-11-30 | 1999-11-11 | Japan Immuno Inc | Non-A, non-B hepatitisverwandte Nukleinsäuren, Antigene und Antikörper und ihre Feststellungsreagenzien |
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| ES2138784T3 (es) * | 1990-12-14 | 2000-01-16 | Innogenetics Nv | Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c. |
| US6007982A (en) * | 1990-12-14 | 1999-12-28 | Innogenetics N.V. | Synthetic antigens for the detection of antibodies to hepatitis C virus |
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| DK0501557T3 (da) * | 1991-03-01 | 1995-04-10 | Akzo Nobel Nv | Peptider, der er immunokemisk reaktive med antistoffer rettet mod hepatitis non-A, non-B-virus |
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| FR2677372B1 (fr) | 1991-06-06 | 1994-11-10 | Pasteur Institut | Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques. |
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| CA2070952A1 (en) * | 1991-06-11 | 1992-12-12 | Makoto Seki | Gene of hepatitis c virus or fragment thereof, polypeptide encoded by the same |
| WO1992022571A1 (en) * | 1991-06-13 | 1992-12-23 | Baxter Diagnostics Inc. | Immunoassay for non-a non-b hepatitis |
| DE69232871T2 (de) | 1991-06-24 | 2003-05-08 | Chiron Corp | Polypeptide des hepatitis c-virus (hiv) |
| IT1249684B (it) * | 1991-07-19 | 1995-03-09 | Sorin Biomedica Spa | Epitopi della proteina env del virus dell'epatite c. |
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Owner name: CHIRON CORPORATION |
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Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC. Free format text: NOVARTIS VACCINES AND DIAGNOSTICS, INC. |