MXPA05008342A - Listeria atenuada para la entrada a las celulas no fagociticas, vacunas que comprenden la listeria, y metodos de uso de las mismas. - Google Patents
Listeria atenuada para la entrada a las celulas no fagociticas, vacunas que comprenden la listeria, y metodos de uso de las mismas.Info
- Publication number
- MXPA05008342A MXPA05008342A MXPA05008342A MXPA05008342A MXPA05008342A MX PA05008342 A MXPA05008342 A MX PA05008342A MX PA05008342 A MXPA05008342 A MX PA05008342A MX PA05008342 A MXPA05008342 A MX PA05008342A MX PA05008342 A MXPA05008342 A MX PA05008342A
- Authority
- MX
- Mexico
- Prior art keywords
- listeria
- attenuated
- methods
- vaccines
- entry
- Prior art date
Links
- 241000186781 Listeria Species 0.000 title abstract 7
- 230000002238 attenuated effect Effects 0.000 title abstract 6
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 210000001539 phagocyte Anatomy 0.000 title abstract 2
- 101710198693 Invasin Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/07—Bacillus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
Abstract
La presente invencion proporciona Listeria que son atenuadas para la entrada a las celulas no fagociticas asi como una variedad de metodos para inducir respuestas inmunes que involucran la administracion de composiciones que incluyen la Listeria atenuada. Algunas de las Listerias atenuadas son Listeria mutantes que comprenden al menos una mutacion en un gen que codifica para una invasina, tal como internalina. Algunas de las Listerias atenuadas son ademas atenuadas para la dispersion de celula a celula. Se proporcionan tambien las composiciones farmaceuticas y las vacunas utiles en los metodos de la invencion. Se proporcionan tambien los metodos para elaborar y mejorar las vacunas.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44605103P | 2003-02-06 | 2003-02-06 | |
US44915303P | 2003-02-21 | 2003-02-21 | |
US49008903P | 2003-07-24 | 2003-07-24 | |
US51171903P | 2003-10-15 | 2003-10-15 | |
US51191903P | 2003-10-15 | 2003-10-15 | |
US51186903P | 2003-10-15 | 2003-10-15 | |
US54151504P | 2004-02-02 | 2004-02-02 | |
PCT/US2004/003429 WO2004110481A2 (en) | 2003-02-06 | 2004-02-06 | Listeria attenuated for entry into non-phagocytic cells, vaccines comprising the listeria, and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05008342A true MXPA05008342A (es) | 2006-02-28 |
Family
ID=33556840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05008342A MXPA05008342A (es) | 2003-02-06 | 2004-02-06 | Listeria atenuada para la entrada a las celulas no fagociticas, vacunas que comprenden la listeria, y metodos de uso de las mismas. |
Country Status (13)
Country | Link |
---|---|
US (2) | US7691393B2 (es) |
EP (1) | EP1592441B1 (es) |
JP (2) | JP4545151B2 (es) |
KR (1) | KR101192652B1 (es) |
AT (1) | ATE552843T1 (es) |
AU (1) | AU2004246999B2 (es) |
CA (1) | CA2515369C (es) |
DK (1) | DK1592441T3 (es) |
ES (1) | ES2382332T3 (es) |
HK (1) | HK1082187A1 (es) |
MX (1) | MXPA05008342A (es) |
PT (1) | PT1592441E (es) |
WO (1) | WO2004110481A2 (es) |
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2004
- 2004-02-06 ES ES04749316T patent/ES2382332T3/es not_active Expired - Lifetime
- 2004-02-06 WO PCT/US2004/003429 patent/WO2004110481A2/en active Application Filing
- 2004-02-06 US US10/773,792 patent/US7691393B2/en active Active
- 2004-02-06 CA CA2515369A patent/CA2515369C/en not_active Expired - Fee Related
- 2004-02-06 DK DK04749316.8T patent/DK1592441T3/da active
- 2004-02-06 JP JP2006532281A patent/JP4545151B2/ja not_active Expired - Fee Related
- 2004-02-06 AT AT04749316T patent/ATE552843T1/de active
- 2004-02-06 EP EP04749316A patent/EP1592441B1/en not_active Expired - Lifetime
- 2004-02-06 AU AU2004246999A patent/AU2004246999B2/en not_active Ceased
- 2004-02-06 KR KR1020057014538A patent/KR101192652B1/ko active IP Right Grant
- 2004-02-06 PT PT04749316T patent/PT1592441E/pt unknown
- 2004-02-06 MX MXPA05008342A patent/MXPA05008342A/es active IP Right Grant
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AU2004246999A1 (en) | 2004-12-23 |
PT1592441E (pt) | 2012-05-21 |
US7691393B2 (en) | 2010-04-06 |
KR20050105460A (ko) | 2005-11-04 |
WO2004110481A3 (en) | 2005-03-03 |
US20040228877A1 (en) | 2004-11-18 |
JP2007125040A (ja) | 2007-05-24 |
ATE552843T1 (de) | 2012-04-15 |
ES2382332T3 (es) | 2012-06-07 |
US8287883B2 (en) | 2012-10-16 |
EP1592441B1 (en) | 2012-04-11 |
CA2515369A1 (en) | 2004-12-23 |
AU2004246999B2 (en) | 2010-06-10 |
HK1082187A1 (en) | 2006-06-02 |
KR101192652B1 (ko) | 2012-10-19 |
WO2004110481A2 (en) | 2004-12-23 |
CA2515369C (en) | 2015-03-31 |
JP4545151B2 (ja) | 2010-09-15 |
JP2007503846A (ja) | 2007-03-01 |
US20110201092A1 (en) | 2011-08-18 |
EP1592441A2 (en) | 2005-11-09 |
DK1592441T3 (da) | 2012-05-14 |
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