FI103279B1 - Menetelmä terapeuttisesti käyttökelpoisten fosfolipidi- tai lipidiliitteisten glykosaminoglykaaniyhdisteiden valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten fosfolipidi- tai lipidiliitteisten glykosaminoglykaaniyhdisteiden valmistamiseksi

Info

Publication number
FI103279B1
FI103279B1 FI920717A FI920717A FI103279B1 FI 103279 B1 FI103279 B1 FI 103279B1 FI 920717 A FI920717 A FI 920717A FI 920717 A FI920717 A FI 920717A FI 103279 B1 FI103279 B1 FI 103279B1
Authority
FI
Finland
Prior art keywords
lipid
phospholipid
derivative
glycosaminoglycan
preparation
Prior art date
Application number
FI920717A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI920717A0 (fi
FI103279B (fi
Inventor
Katsukiyo Sakurai
Nobuo Sugiura
Koji Kimata
Sakaru Suzuki
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2193817A external-priority patent/JP2997018B2/ja
Priority claimed from JP2193816A external-priority patent/JP2986518B2/ja
Priority claimed from JP2193818A external-priority patent/JP2986519B2/ja
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Publication of FI920717A0 publication Critical patent/FI920717A0/fi
Application granted granted Critical
Publication of FI103279B publication Critical patent/FI103279B/fi
Publication of FI103279B1 publication Critical patent/FI103279B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI920717A 1990-07-24 1992-02-19 Menetelmä terapeuttisesti käyttökelpoisten fosfolipidi- tai lipidiliitteisten glykosaminoglykaaniyhdisteiden valmistamiseksi FI103279B1 (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP2193817A JP2997018B2 (ja) 1990-07-24 1990-07-24 燐脂質又は脂質結合グリコサミノグリカン
JP19381890 1990-07-24
JP2193816A JP2986518B2 (ja) 1990-07-24 1990-07-24 癌転移抑制剤
JP2193818A JP2986519B2 (ja) 1990-07-24 1990-07-24 燐脂質結合グリコサミノグリカン
JP19381790 1990-07-24
JP19381690 1990-07-24
PCT/JP1991/000995 WO1992001720A1 (en) 1990-07-24 1991-07-24 Phospholipid- or lipid-combining glycosaminoglycan, production thereof, and cancer metastasis inhibitor
JP9100995 1991-07-24

Publications (3)

Publication Number Publication Date
FI920717A0 FI920717A0 (fi) 1992-02-19
FI103279B FI103279B (fi) 1999-05-31
FI103279B1 true FI103279B1 (fi) 1999-05-31

Family

ID=27326820

Family Applications (1)

Application Number Title Priority Date Filing Date
FI920717A FI103279B1 (fi) 1990-07-24 1992-02-19 Menetelmä terapeuttisesti käyttökelpoisten fosfolipidi- tai lipidiliitteisten glykosaminoglykaaniyhdisteiden valmistamiseksi

Country Status (10)

Country Link
US (1) US5464942A (no)
EP (1) EP0493622B1 (no)
KR (1) KR0181295B1 (no)
AT (1) ATE148713T1 (no)
AU (1) AU647814B2 (no)
CA (1) CA2067211C (no)
DE (1) DE69124590T2 (no)
FI (1) FI103279B1 (no)
NO (1) NO305368B1 (no)
WO (1) WO1992001720A1 (no)

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IT1260137B (it) * 1992-04-17 1996-03-28 Alfa Wassermann Spa Glicosaminoglicani semisintetici a struttura eparinica od eparanica modificati nella posizione 2 dell'acido alfa-l-iduronico-2-0-solfato
RU2157239C2 (ru) * 1992-07-13 2000-10-10 Юкэрион, Инк. Способ модификации, способ обеспечения связывания белка с антителом, фармацевтические композиции, способ диагностики
JP3714683B2 (ja) * 1992-07-30 2005-11-09 生化学工業株式会社 抗リウマチ剤
JP2787279B2 (ja) * 1994-05-17 1998-08-13 雪印乳業株式会社 糖リン脂質及びその調製法
US6228998B1 (en) 1994-07-22 2001-05-08 Seikagaku Kogyo Kabushiki Kaisha Amino spacered glycosaminoglycan derivatives and their use in copolymerization with acrylamide
FR2725622A1 (fr) * 1994-10-14 1996-04-19 Fabre Pierre Dermo Cosmetique Ceramide greffee anti-elastase
CA2175282A1 (en) * 1996-04-29 1997-10-30 Rudolf Edgar Falk Use of forms of hyaluronic acid (ha) for the treatment of cancer
AU2602200A (en) * 1999-01-08 2000-07-24 Board Of Trustees Of The University Of Arkansas, The Synthetic, highly charged molecules and uses thereof
JP3032824B1 (ja) * 1999-01-28 2000-04-17 東京医科歯科大学長 骨誘導促進剤
AU6472900A (en) * 1999-08-10 2001-03-13 Seikagaku Corporation Glycosaminoglycan derivatives and utilization thereof
US8501701B2 (en) * 2000-01-10 2013-08-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Use of lipid conjugates in the treatment of disease
US7811999B2 (en) * 2000-01-10 2010-10-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Use of lipid conjugates in the treatment of diseases
US7141552B2 (en) * 2000-01-10 2006-11-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases
US8304395B2 (en) * 2000-01-10 2012-11-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Lipid conjugates in the treatment of disease
US7608598B2 (en) * 2000-01-10 2009-10-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of conjunctivitis
US7101859B2 (en) * 2000-01-10 2006-09-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases
US20060189571A1 (en) * 2000-01-10 2006-08-24 Saul Yedgar Use of lipid conjugates in the treatment of infection
US8916539B2 (en) * 2000-01-10 2014-12-23 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of disease
US9040078B2 (en) * 2000-01-10 2015-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases of the nervous system
US20090325876A1 (en) * 2004-09-29 2009-12-31 Saul Yedgar Use of lipid conjugates in the treatment of diseases associated with vasculature
US7893226B2 (en) 2004-09-29 2011-02-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Use of lipid conjugates in the treatment of diseases
US7393938B2 (en) * 2000-01-10 2008-07-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases
US7772196B2 (en) * 2000-01-10 2010-08-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases
US8076312B2 (en) * 2000-01-10 2011-12-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Use of lipid conjugates in the treatment of disease
US7259152B2 (en) 2000-06-07 2007-08-21 Alfa Wasserman, Inc. Methods and compositions using sulodexide for the treatment of diabetic nephropathy
US8883761B2 (en) * 2001-01-10 2014-11-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of lipid conjugates in the treatment of diseases associated with vasculature
US7280612B2 (en) * 2003-07-25 2007-10-09 Zarbana Digital Fund Llc Digital branch calibrator for an RF transmitter
WO2005040224A1 (ja) * 2003-10-29 2005-05-06 Teijin Limited ヒアルロン酸化合物、そのハイドロゲルおよび関節治療用材料
EA200800489A1 (ru) * 2005-08-03 2008-12-30 Морриа Байофармасьютикалс Применение липидных конъюгатов при муковисцидозе и их приложения
JP4744973B2 (ja) * 2005-08-05 2011-08-10 株式会社トプコン 眼底カメラ
US8475694B2 (en) 2005-10-25 2013-07-02 Zephyros, Inc. Shaped expandable material
US8859524B2 (en) 2005-11-17 2014-10-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Lipid conjugates in the treatment of chronic rhinosinusitis
US8906882B2 (en) 2005-11-17 2014-12-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Lipid conjugates in the treatment of allergic rhinitis
US20080183282A1 (en) * 2006-03-09 2008-07-31 Saul Yedgar Use of lipid conjugates for the coating of stents and catheters
CA2705785A1 (en) * 2006-11-14 2008-05-22 Saul Yedgar Use of lipid conjugates in the treatment of diseases or disorders of the eye
EP2097086A4 (en) * 2006-11-14 2012-01-11 Yissum Res Dev Co CONTACT LENS COMPOSITIONS
JP2012526819A (ja) * 2009-05-11 2012-11-01 イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム リミテッド 脂質−ポリマー複合体、その調製、及びその使用
GB0916205D0 (en) 2009-09-15 2009-10-28 Zephyros Inc Improvements in or relating to cavity filling
US20130012473A1 (en) * 2010-03-17 2013-01-10 Ktb Tumorforschungsgesellschaft Mbh Combined use of phospholipid and sulfate groups-carrying polysaccharides for inhibiting metastatic spread
CA2703532C (en) * 2010-05-10 2018-05-01 Eva Turley Topically administered, skin-penetrating glycosaminoglycan formulations suitable for use in cosmetic and pharmaceutical applications
CN114096567A (zh) * 2019-04-29 2022-02-25 鲍希与洛姆伯股份有限公司 糖磷脂聚合物网络及其用途

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EP0114589B1 (en) * 1982-12-20 1987-09-23 The President And Fellows Of Harvard College Inhibition of angiogenesis
JPS6117A (ja) * 1984-06-11 1986-01-06 Seikagaku Kogyo Co Ltd ムコ多糖系癌転移抑制剤
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JPH03220201A (ja) * 1988-11-18 1991-09-27 Eisai Co Ltd プロスタグランジン類と多糖類の結合体

Also Published As

Publication number Publication date
EP0493622A4 (en) 1993-10-27
EP0493622B1 (en) 1997-02-05
AU647814B2 (en) 1994-03-31
US5464942A (en) 1995-11-07
WO1992001720A1 (en) 1992-02-06
CA2067211A1 (en) 1992-01-25
AU8226691A (en) 1992-02-18
ATE148713T1 (de) 1997-02-15
CA2067211C (en) 2004-06-15
NO921083L (no) 1992-05-21
FI920717A0 (fi) 1992-02-19
NO921083D0 (no) 1992-03-19
DE69124590T2 (de) 1997-06-12
FI103279B (fi) 1999-05-31
KR920702377A (ko) 1992-09-03
EP0493622A1 (en) 1992-07-08
DE69124590D1 (de) 1997-03-20
KR0181295B1 (ko) 1999-04-01
NO305368B1 (no) 1999-05-18

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