ES8704445A1 - Procedimiento de preparar derivados aminicos - Google Patents

Procedimiento de preparar derivados aminicos

Info

Publication number
ES8704445A1
ES8704445A1 ES552827A ES552827A ES8704445A1 ES 8704445 A1 ES8704445 A1 ES 8704445A1 ES 552827 A ES552827 A ES 552827A ES 552827 A ES552827 A ES 552827A ES 8704445 A1 ES8704445 A1 ES 8704445A1
Authority
ES
Spain
Prior art keywords
preparation
formula
phenylisopropylamine derivative
methyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552827A
Other languages
English (en)
Other versions
ES552827A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of ES8704445A1 publication Critical patent/ES8704445A1/es
Publication of ES552827A0 publication Critical patent/ES552827A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DEL COMPUESTO DE FORMULA (I) Y DE SUS ISOMEROS Y SALES. COMPRENDE LA REACCION DE UN DERIVADO 2-FENILISOPROPILICO, DE FORMULA (II) CON UN COMPUESTO DE FORMULA B-R1, EN LAS QUE R1 ES METILO O PROPILO O GENERADORES DE LOS MISMOS, R2 ES FLUOR O GENERADOR DE FLUOR Y A Y B PUEDEN SER VARIOS RADICALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS EFECTOS GERIATRICOS, ANTIDEPRESORES DE INHIBICION Y CONTRA LA ENFERMEDAD DE PARKINSON.
ES552827A 1984-05-31 1986-02-28 Procedimiento de preparar derivados aminicos Expired ES8704445A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU842124A HU207282B (en) 1984-05-31 1984-05-31 Process for producing phenyl-alkyl-amine derivatives and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
ES8704445A1 true ES8704445A1 (es) 1987-04-16
ES552827A0 ES552827A0 (es) 1987-04-16

Family

ID=10957881

Family Applications (2)

Application Number Title Priority Date Filing Date
ES544400A Expired ES8609204A1 (es) 1984-05-31 1985-05-31 Procedimiento de preparar derivados aminicos
ES552827A Expired ES8704445A1 (es) 1984-05-31 1986-02-28 Procedimiento de preparar derivados aminicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES544400A Expired ES8609204A1 (es) 1984-05-31 1985-05-31 Procedimiento de preparar derivados aminicos

Country Status (23)

Country Link
US (2) US5008292A (es)
EP (1) EP0186680B1 (es)
JP (2) JPS61502259A (es)
AT (1) AT394552B (es)
AU (1) AU588757B2 (es)
BG (1) BG61318B2 (es)
CH (1) CH671574A5 (es)
CS (1) CS271313B2 (es)
DD (1) DD235065A5 (es)
DE (2) DE3590241T (es)
DK (1) DK166018C (es)
ES (2) ES8609204A1 (es)
FI (1) FI92053C (es)
GB (1) GB2171694B (es)
GE (3) GEP19970786B (es)
HU (1) HU207282B (es)
IL (1) IL75358A (es)
MX (1) MX9203090A (es)
PL (2) PL150477B1 (es)
PT (1) PT80574B (es)
SE (1) SE463261B (es)
SU (3) SU1487810A3 (es)
WO (1) WO1985005617A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582060D1 (de) * 1984-11-22 1991-04-11 Sandoz Ag Homopropargylamine.
US5225446A (en) * 1990-08-31 1993-07-06 Deprenyl Animal Health, Inc. Use of 1-deprenyl for retention of specific physiological functions
US5767164A (en) * 1991-04-04 1998-06-16 Innovations Foundation Use of deprenyl to rescue damaged nerve cells
US5844003A (en) * 1991-04-04 1998-12-01 Innovations Foundation Use of deprenyl compounds to maintain, prevent loss, or recover nerve cell function
US5444095A (en) * 1991-04-04 1995-08-22 University Of Toronto, Innovations Foundation Use of deprenyl to rescue damaged nerve cells
IL99759A (en) * 1991-10-16 1997-06-10 Teva Pharma Mono-fluorinated derivatives of n-propargyl-1-aminoindan, their preparation and pharmaceutical compositions containing them
HUT63579A (en) * 1991-12-20 1993-09-28 Chinoin Gyogyszer Es Vegyeszet Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes
US5169536A (en) * 1992-04-28 1992-12-08 Betz Laboratories, Inc. Detoxification agents for surfactant based biocides
IES61604B2 (en) * 1993-12-16 1994-11-16 Russinsky Ltd A process for producing pharmaceutical compounds
US5516747A (en) * 1994-04-18 1996-05-14 Henkel Corporation Pesticidal surfactant mixtures comprising alkyl polyglycosides and alkyl naphthalene sulfonates
PT762877E (pt) * 1994-06-03 2001-08-30 Thejmde Trust Arilalquilaminas meta-substituidas e suas aplicacoes terapeuticas e de diagnostico
HU218927B (hu) * 1994-11-22 2000-12-28 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Eljárás propargil-ammónium-klorid-származékok előállítására
CA2212412A1 (en) 1995-02-10 1996-08-15 The University Of Toronto Innovations Foundation Deprenyl compounds for treatment of glaucoma
JP3087891B2 (ja) 1998-03-31 2000-09-11 東洋紡績株式会社 電解質測定用試薬組成物
HUP9902482A2 (hu) * 1999-07-22 2002-04-29 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. P-fluoro-selegilin alkalmazása neuroprotektív gyógyszerkészítmények előállítására
AU2006265639A1 (en) * 2005-07-01 2007-01-11 Jenrin Discovery MAO-B inhibitors useful for treating obesity
EP2053033A1 (en) * 2007-10-26 2009-04-29 Bayer Schering Pharma AG Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors
CN102180798B (zh) * 2011-03-18 2013-11-06 湖北汉星化工新材料有限公司 一步法催化合成n,n-二乙基丙炔胺的方法
WO2015087094A1 (en) * 2013-12-10 2015-06-18 Semmelweis Egyetem New arylalkenylpropargylamine derivatives exhibiting neuroprotective action for the treatment of neurodegenerative diseases

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1311843A (fr) * 1961-09-06 1962-12-14 Abbott Lab Procédé de préparation de nu-halobenzyl-nu-méthyl-2-propynylamines
US3142554A (en) * 1961-10-10 1964-07-28 Monsanto Co Controlling vegetation with aryl thioalkylamines
GB1027611A (en) * 1962-01-04 1966-04-27 May & Baker Ltd Phenoxy- and phenylthio-alkylamines and acid addition salts thereof
DE1227447B (de) * 1962-03-30 1966-10-27 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von Phenylisopropylaminen
GB1031425A (en) * 1962-03-30 1966-06-02 Chinoin Gyogyszer Es Vegyeszet New aralkylamines and their preparation
GB1121857A (en) * 1965-01-05 1968-07-31 Science Union & Cie New phenylisopropylamine derivatives and process for their preparation and pharmaceutical preparations of such derivatives
CH491855A (de) * 1965-02-08 1970-06-15 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Phenylisopropyl-Derivaten
US3485874A (en) * 1966-05-04 1969-12-23 Chinoin Gyogyszer Es Vegyeszet Ortho and para bromophenyl isopropyl methylamines
US3496195A (en) * 1966-05-11 1970-02-17 Chinoin Gyogyszer Es Vegyeszet D-o-bromo-phenyl-isopropyl-methylpropinylamine and its salts
US4137328A (en) * 1970-07-18 1979-01-30 Pfizer Inc. Phenyl-alkanolamine, alkylamine and α-aminoalkyl ketone derivatives as heart stimulants
US3689504A (en) * 1970-12-24 1972-09-05 Abbott Lab N-substituted -alpha-methyl-3,4-(methylenedioxy) phenethylamines
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
US4105695A (en) * 1975-12-11 1978-08-08 Bristol-Myers Company 2-Amino-1-(2,5-dimethoxyphenyl)-butanes
US4156017A (en) * 1977-02-22 1979-05-22 Schering Aktiengesellschaft Pesticides
US4200654A (en) * 1978-11-24 1980-04-29 Abbott Laboratories Ovicides
FR2486074A1 (fr) * 1979-12-14 1982-01-08 Lafon Labor Derives de fluorophenacyl-amine, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
DK166018B (da) 1993-03-01
GB8602394D0 (en) 1986-03-05
CS389585A2 (en) 1989-12-13
SU1487810A3 (ru) 1989-06-15
JPH0819057B2 (ja) 1996-02-28
JPH0564942B2 (es) 1993-09-16
FI860101A (fi) 1986-01-09
US4960797A (en) 1990-10-02
GEP19970818B (en) 1997-01-30
DE3590241C2 (es) 1991-08-01
US5008292A (en) 1991-04-16
AT394552B (de) 1992-05-11
JPH0687798A (ja) 1994-03-29
ES8609204A1 (es) 1986-09-01
FI92053B (fi) 1994-06-15
GEP19970786B (en) 1997-01-20
EP0186680B1 (en) 1988-03-30
SU1549477A3 (ru) 1990-03-07
AU588757B2 (en) 1989-09-21
DD235065A5 (de) 1986-04-23
PT80574B (pt) 1987-08-19
DE3590241T (de) 1986-06-26
GEP19960459B (en) 1996-07-15
SU1609443A3 (ru) 1990-11-23
GB2171694A (en) 1986-09-03
PT80574A (en) 1985-06-01
MX9203090A (es) 1992-07-01
AU4437585A (en) 1985-12-31
DK45786A (da) 1986-01-30
CH671574A5 (es) 1989-09-15
SE463261B (sv) 1990-10-29
HU207282B (en) 1993-03-29
ES544400A0 (es) 1986-09-01
SE8600413L (sv) 1986-01-30
PL149288B1 (en) 1990-01-31
EP0186680A1 (en) 1986-07-09
PL253737A1 (en) 1987-02-23
CS271313B2 (en) 1990-09-12
DK45786D0 (da) 1986-01-30
DK166018C (da) 1993-07-12
WO1985005617A1 (en) 1985-12-19
HUT37385A (en) 1985-12-28
SE8600413D0 (sv) 1986-01-30
PL150477B1 (en) 1990-05-31
IL75358A (en) 1988-10-31
JPS61502259A (ja) 1986-10-09
ATA901585A (de) 1991-10-15
GB2171694B (en) 1987-12-09
FI92053C (fi) 1994-09-26
BG61318B2 (bg) 1997-05-30
ES552827A0 (es) 1987-04-16
FI860101A0 (fi) 1986-01-09

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040916