ES8503669A1 - Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos. - Google Patents

Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos.

Info

Publication number
ES8503669A1
ES8503669A1 ES523609A ES523609A ES8503669A1 ES 8503669 A1 ES8503669 A1 ES 8503669A1 ES 523609 A ES523609 A ES 523609A ES 523609 A ES523609 A ES 523609A ES 8503669 A1 ES8503669 A1 ES 8503669A1
Authority
ES
Spain
Prior art keywords
derivatives
compounds
procedure
formula
imidazolylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523609A
Other languages
English (en)
Spanish (es)
Other versions
ES523609A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of ES523609A0 publication Critical patent/ES523609A0/es
Publication of ES8503669A1 publication Critical patent/ES8503669A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES523609A 1982-07-05 1983-06-27 Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos. Expired ES8503669A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8219412 1982-07-05

Publications (2)

Publication Number Publication Date
ES523609A0 ES523609A0 (es) 1985-03-01
ES8503669A1 true ES8503669A1 (es) 1985-03-01

Family

ID=10531484

Family Applications (1)

Application Number Title Priority Date Filing Date
ES523609A Expired ES8503669A1 (es) 1982-07-05 1983-06-27 Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos.

Country Status (33)

Country Link
US (2) US4510149A (en, 2012)
JP (1) JPS5927874A (en, 2012)
KR (1) KR910000414B1 (en, 2012)
AT (1) AT386201B (en, 2012)
AU (1) AU557304B2 (en, 2012)
BE (1) BE897207A (en, 2012)
CA (1) CA1202030A (en, 2012)
CH (1) CH655102A5 (en, 2012)
CS (1) CS273310B2 (en, 2012)
CZ (1) CZ413491A3 (en, 2012)
DE (1) DE3324069C2 (en, 2012)
DK (1) DK163359C (en, 2012)
ES (1) ES8503669A1 (en, 2012)
FI (1) FI74466C (en, 2012)
FR (1) FR2529547B1 (en, 2012)
GR (1) GR77577B (en, 2012)
HK (1) HK101187A (en, 2012)
HU (1) HU193529B (en, 2012)
IE (1) IE55894B1 (en, 2012)
IL (1) IL69152A0 (en, 2012)
IT (1) IT1163641B (en, 2012)
LU (1) LU84895A1 (en, 2012)
MY (1) MY104376A (en, 2012)
NL (1) NL8302347A (en, 2012)
NO (1) NO161439C (en, 2012)
NZ (1) NZ204802A (en, 2012)
PH (1) PH21115A (en, 2012)
PT (1) PT76979B (en, 2012)
SE (1) SE461791B (en, 2012)
SG (1) SG73487G (en, 2012)
SU (1) SU1342414A3 (en, 2012)
YU (1) YU43545B (en, 2012)
ZA (1) ZA834865B (en, 2012)

Families Citing this family (33)

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PH22076A (en) * 1983-08-25 1988-05-20 Daiichi Seiyaku Co Benzocycloalkane derivative
JPH062745B2 (ja) * 1984-07-16 1994-01-12 第一製薬株式会社 インダン誘導体
US4659730A (en) * 1984-06-18 1987-04-21 Eli Lilly And Company Aromatase inhibiting imidazole derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
GB8612796D0 (en) * 1986-05-27 1986-07-02 Fbc Ltd Fungicides
GB2205240B (en) * 1987-06-03 1991-01-09 Erba Carlo Spa N-imidazolyl derivatives of bicyclic compounds useful in medicine
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
IL91542A0 (en) * 1988-10-06 1990-04-29 Erba Carlo Spa N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them
GB9025848D0 (en) * 1990-11-28 1991-01-09 Erba Carlo Spa Imidazol-2-yl derivatives of substituted bicyclic compounds and process for their preparation
GB9102862D0 (en) * 1991-02-11 1991-03-27 Erba Carlo Spa N-imidazolyl derivatives of substituted or alkoxymino tetrahydronaphthalenes and chromans
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9127430D0 (en) * 1991-12-27 1992-02-19 Scras Benzofuranylimidazole derivatives
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
WO1995020587A1 (en) * 1994-01-31 1995-08-03 Pfizer Inc. Neuroprotective chroman compounds
US5559248A (en) * 1995-04-05 1996-09-24 Bristol-Myers Squibb Co. Retinoid-like heterocycles
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
GB9520150D0 (en) * 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
GC0000177A (en) 1998-12-17 2006-03-29 Smithkline Beecham Thrombopoietin mimetics
CY2010012I2 (el) * 2000-05-25 2020-05-29 Novartis Ag Μιμητικα θρομβοποιητινης
US20110212054A1 (en) * 2000-05-25 2011-09-01 Glaxosmithkline Llc. Thrombopoietin mimetics
DE10054639B4 (de) * 2000-11-03 2004-05-06 Jenapharm Gmbh & Co. Kg Verwendung von RanBPM als Co-Modulator von Steroidhormonrezeptoren
US6875786B2 (en) 2001-03-01 2005-04-05 Smithkline Beecham Corporation Thrombopoietin mimetics
TWI280128B (en) * 2002-05-22 2007-05-01 Smithkline Beecham Corp 3'-[(2Z)-[1-(3,4- dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid bis-(monoethanolamine)
DE602004001459T2 (de) * 2003-04-16 2007-02-01 Huntsman Advanced Materials (Switzerland) Gmbh 1-imidazolylmethyl-substituierte 2-naphtole und ihre verwendung als beschleuniger für tieftemperaturhärtung
TW200526638A (en) * 2003-10-22 2005-08-16 Smithkline Beecham Corp 2-(3,4-dimethylphenyl)-4-{[2-hydroxy-3'-(1H-tetrazol-5-yl)biphenyl-3-yl]-hydrazono}-5-methyl-2,4-dihydropyrazol-3-one choline
EP1853261B1 (de) * 2005-03-03 2017-01-11 Universität des Saarlandes Selektive hemmstoffe humaner corticoidsynthasen
KR20090094374A (ko) * 2006-12-18 2009-09-04 노파르티스 아게 1-치환된 이미다졸 유도체 및 알도스테론 신타제 억제제로서의 그의 용도
ECSP077628A (es) 2007-05-03 2008-12-30 Smithkline Beechman Corp Nueva composición farmacéutica
SG176088A1 (en) 2009-05-29 2011-12-29 Glaxosmithkline Llc Methods of administration of thrombopoietin agonist compounds
WO2016022448A1 (en) * 2014-08-08 2016-02-11 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds

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US2443671A (en) * 1942-12-03 1948-06-22 Westinghouse Electric Corp Arc welding system
US3485917A (en) * 1966-04-14 1969-12-23 Janssen Pharmaceutica Nv Composition and method for combating fungus with imidazole carboxylates
US3541109A (en) * 1968-06-25 1970-11-17 Du Pont 1-substituted imidazoles useful in acth reserve assay
US3637731A (en) * 1968-07-18 1972-01-25 Du Pont 1-(alkylsubstituted phenyl)imidazoles useful in acth reserve assay
DE2418502C3 (de) * 1974-04-11 1980-04-24 Schering Ag, 1000 Berlin Und 4619 Bergkamen Dichlorbenzyl- [2-( a -imidazolylbutyl)-phenyl] -äther und -thioäther, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
IE40911B1 (en) * 1974-04-11 1979-09-12 Schering Ag Imidazole derivatives and process for their manufacture
US4284641A (en) * 1977-08-26 1981-08-18 Burroughs Wellcome Co. Pharmaceutically active imidazole derivatives
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative
JPS5681566A (en) * 1979-12-05 1981-07-03 Yoshitomi Pharmaceut Ind Ltd Imidazole derivative
DE3167014D1 (en) * 1980-02-14 1984-12-13 Sandoz Ag A method for the total synthesis of cyclosporins and novel cyclosporins
IL62122A0 (en) * 1980-03-04 1981-03-31 Erba Farmitalia N-imidazolyl derivatives of 1-chroman,their preparation and pharmaceutical compositions containing them
GB2071655B (en) * 1980-03-04 1983-06-22 Erba Farmitalia N-amidazolyl derivatives of1-chroman and process for their preparation
ZA81980B (en) * 1980-03-04 1982-02-24 Erba Farmitalia N-imidazolyl derivatives of 1-chroman and process for their preparation
ZA825142B (en) * 1981-07-23 1983-04-27 Erba Farmitalia N-imidazolyl derivatives of 1,2,3,j-tetrahydro-naphthalene, indan and 2-substituted-1-chroman, and process for their preparation
IL66242A0 (en) * 1981-07-23 1982-11-30 Erba Farmitalia N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene,indan and 2-substituted-1-chroman,their preparation and pharmaceutical compositions containing them
ZA825413B (en) * 1981-08-26 1983-06-29 Pfizer Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them
JPS6081566A (ja) * 1983-10-07 1985-05-09 Nissan Motor Co Ltd ロツクアツプトルクコンバ−タのスリツプ制御装置

Also Published As

Publication number Publication date
ZA834865B (en) 1984-03-28
NO832437L (no) 1984-01-06
YU144283A (en) 1986-10-31
CZ413491A3 (en) 1993-10-13
SG73487G (en) 1988-03-04
JPS5927874A (ja) 1984-02-14
JPH0454662B2 (en, 2012) 1992-08-31
CS273310B2 (en) 1991-03-12
AU1654083A (en) 1984-01-12
IL69152A0 (en) 1983-11-30
ES523609A0 (es) 1985-03-01
FI74466C (fi) 1988-02-08
DE3324069A1 (de) 1984-01-26
KR840005433A (ko) 1984-11-12
IT8321886A0 (it) 1983-07-01
AT386201B (de) 1988-07-25
LU84895A1 (fr) 1983-11-23
YU43545B (en) 1989-08-31
DE3324069C2 (de) 1994-08-25
NO161439B (no) 1989-05-08
GR77577B (en, 2012) 1984-09-24
IE831564L (en) 1984-01-05
MY104376A (en) 1994-03-31
CA1202030A (en) 1986-03-18
FI832420A0 (fi) 1983-07-01
CH655102A5 (de) 1986-03-27
SU1342414A3 (ru) 1987-09-30
US4510149A (en) 1985-04-09
CS509483A2 (en) 1990-08-14
US4602022A (en) 1986-07-22
ATA247383A (de) 1987-12-15
KR910000414B1 (ko) 1991-01-25
NO161439C (no) 1989-08-16
AU557304B2 (en) 1986-12-18
DK163359B (da) 1992-02-24
IT1163641B (it) 1987-04-08
IE55894B1 (en) 1991-02-14
FI832420L (fi) 1984-01-06
HK101187A (en) 1988-01-08
PT76979B (en) 1986-01-09
FI74466B (fi) 1987-10-30
FR2529547B1 (fr) 1986-09-05
PH21115A (en) 1987-07-16
SE8303824L (sv) 1984-01-06
DK307983A (da) 1984-01-06
DK307983D0 (da) 1983-07-04
DK163359C (da) 1992-07-13
PT76979A (en) 1983-08-01
FR2529547A1 (fr) 1984-01-06
SE461791B (sv) 1990-03-26
NZ204802A (en) 1986-04-11
BE897207A (fr) 1984-01-04
NL8302347A (nl) 1984-02-01
HU193529B (en) 1987-10-28
SE8303824D0 (sv) 1983-07-04

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519