DK163359C - Analogifremgangsmaade til fremstilling af n-imidazolylderivater af bicycliske forbindelser eller pharmaceutisk acceptable salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af n-imidazolylderivater af bicycliske forbindelser eller pharmaceutisk acceptable salte deraf

Info

Publication number
DK163359C
DK163359C DK307983A DK307983A DK163359C DK 163359 C DK163359 C DK 163359C DK 307983 A DK307983 A DK 307983A DK 307983 A DK307983 A DK 307983A DK 163359 C DK163359 C DK 163359C
Authority
DK
Denmark
Prior art keywords
analogue
preparation
acceptable salts
pharmaceutical acceptable
bicyclic compounds
Prior art date
Application number
DK307983A
Other languages
English (en)
Other versions
DK307983A (da
DK307983D0 (da
DK163359B (da
Inventor
Paolo Cozzi
Germano Carganico
Antonio Pillan
Umberto Branzoli
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of DK307983D0 publication Critical patent/DK307983D0/da
Publication of DK307983A publication Critical patent/DK307983A/da
Publication of DK163359B publication Critical patent/DK163359B/da
Application granted granted Critical
Publication of DK163359C publication Critical patent/DK163359C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK307983A 1982-07-05 1983-07-04 Analogifremgangsmaade til fremstilling af n-imidazolylderivater af bicycliske forbindelser eller pharmaceutisk acceptable salte deraf DK163359C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8219412 1982-07-05
GB8219412 1982-07-05

Publications (4)

Publication Number Publication Date
DK307983D0 DK307983D0 (da) 1983-07-04
DK307983A DK307983A (da) 1984-01-06
DK163359B DK163359B (da) 1992-02-24
DK163359C true DK163359C (da) 1992-07-13

Family

ID=10531484

Family Applications (1)

Application Number Title Priority Date Filing Date
DK307983A DK163359C (da) 1982-07-05 1983-07-04 Analogifremgangsmaade til fremstilling af n-imidazolylderivater af bicycliske forbindelser eller pharmaceutisk acceptable salte deraf

Country Status (33)

Country Link
US (2) US4510149A (da)
JP (1) JPS5927874A (da)
KR (1) KR910000414B1 (da)
AT (1) AT386201B (da)
AU (1) AU557304B2 (da)
BE (1) BE897207A (da)
CA (1) CA1202030A (da)
CH (1) CH655102A5 (da)
CS (1) CS273310B2 (da)
CZ (1) CZ413491A3 (da)
DE (1) DE3324069C2 (da)
DK (1) DK163359C (da)
ES (1) ES523609A0 (da)
FI (1) FI74466C (da)
FR (1) FR2529547B1 (da)
GR (1) GR77577B (da)
HK (1) HK101187A (da)
HU (1) HU193529B (da)
IE (1) IE55894B1 (da)
IL (1) IL69152A0 (da)
IT (1) IT1163641B (da)
LU (1) LU84895A1 (da)
MY (1) MY104376A (da)
NL (1) NL8302347A (da)
NO (1) NO161439C (da)
NZ (1) NZ204802A (da)
PH (1) PH21115A (da)
PT (1) PT76979B (da)
SE (1) SE461791B (da)
SG (1) SG73487G (da)
SU (1) SU1342414A3 (da)
YU (1) YU43545B (da)
ZA (1) ZA834865B (da)

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JPH062745B2 (ja) * 1984-07-16 1994-01-12 第一製薬株式会社 インダン誘導体
PH22076A (en) * 1983-08-25 1988-05-20 Daiichi Seiyaku Co Benzocycloalkane derivative
US4659730A (en) * 1984-06-18 1987-04-21 Eli Lilly And Company Aromatase inhibiting imidazole derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
GB8612796D0 (en) * 1986-05-27 1986-07-02 Fbc Ltd Fungicides
JPS63310825A (ja) * 1987-06-03 1988-12-19 フアルミタリア・カルロ・エルバ・エツセ・エルレ・エルレ 医薬に有用な二環式化合物のｎ−イミダゾリル誘導体
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
IL91542A0 (en) * 1988-10-06 1990-04-29 Erba Carlo Spa N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them
GB9025848D0 (en) * 1990-11-28 1991-01-09 Erba Carlo Spa Imidazol-2-yl derivatives of substituted bicyclic compounds and process for their preparation
GB9102862D0 (en) * 1991-02-11 1991-03-27 Erba Carlo Spa N-imidazolyl derivatives of substituted or alkoxymino tetrahydronaphthalenes and chromans
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9127430D0 (en) * 1991-12-27 1992-02-19 Scras Benzofuranylimidazole derivatives
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
US5559248A (en) * 1995-04-05 1996-09-24 Bristol-Myers Squibb Co. Retinoid-like heterocycles
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
GB9520150D0 (en) 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
GC0000177A (en) 1998-12-17 2006-03-29 Smithkline Beecham Thrombopoietin mimetics
CY2010012I2 (el) * 2000-05-25 2020-05-29 Novartis Ag Μιμητικα θρομβοποιητινης
US20110212054A1 (en) * 2000-05-25 2011-09-01 Glaxosmithkline Llc. Thrombopoietin mimetics
DE10054639B4 (de) * 2000-11-03 2004-05-06 Jenapharm Gmbh & Co. Kg Verwendung von RanBPM als Co-Modulator von Steroidhormonrezeptoren
US6875786B2 (en) 2001-03-01 2005-04-05 Smithkline Beecham Corporation Thrombopoietin mimetics
AR040083A1 (es) * 2002-05-22 2005-03-16 Smithkline Beecham Corp Compuesto bis-(monoetanolamina) del acido 3'-[(2z)-[1-(3,4-dimetilfenil) -1,5-dihidro-3-metil-5-oxo-4h-pirazol-4-iliden] hidrazino] -2'-hidroxi-[1,1'-bifenil]-3-carboxilico, procedimiento para prepararlo, composicion farmaceutica que lo comprende, procedimiento para preparar dicha composicion farmac
DE602004001459T2 (de) * 2003-04-16 2007-02-01 Huntsman Advanced Materials (Switzerland) Gmbh 1-imidazolylmethyl-substituierte 2-naphtole und ihre verwendung als beschleuniger für tieftemperaturhärtung
TW200526638A (en) * 2003-10-22 2005-08-16 Smithkline Beecham Corp 2-(3,4-dimethylphenyl)-4-{[2-hydroxy-3'-(1H-tetrazol-5-yl)biphenyl-3-yl]-hydrazono}-5-methyl-2,4-dihydropyrazol-3-one choline
US9271963B2 (en) * 2005-03-03 2016-03-01 Universitat Des Saarlandes Selective inhibitors of human corticosteroid synthases
BRPI0721290A2 (pt) * 2006-12-18 2014-03-25 Novartis Ag Compostos orgânicos
ECSP077628A (es) * 2007-05-03 2008-12-30 Smithkline Beechman Corp Nueva composición farmacéutica
JP2012528184A (ja) 2009-05-29 2012-11-12 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー トロンボポエチンアゴニスト化合物の投与の方法
US10662171B2 (en) * 2014-08-08 2020-05-26 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds

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US3485917A (en) * 1966-04-14 1969-12-23 Janssen Pharmaceutica Nv Composition and method for combating fungus with imidazole carboxylates
US3541109A (en) * 1968-06-25 1970-11-17 Du Pont 1-substituted imidazoles useful in acth reserve assay
US3637731A (en) * 1968-07-18 1972-01-25 Du Pont 1-(alkylsubstituted phenyl)imidazoles useful in acth reserve assay
IE40911B1 (en) * 1974-04-11 1979-09-12 Schering Ag Imidazole derivatives and process for their manufacture
DE2418502C3 (de) * 1974-04-11 1980-04-24 Schering Ag, 1000 Berlin Und 4619 Bergkamen Dichlorbenzyl- [2-( a -imidazolylbutyl)-phenyl] -äther und -thioäther, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
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AU548156B2 (en) * 1980-02-14 1985-11-28 Novartis Ag Cyclo sporin
US4342775A (en) * 1980-03-04 1982-08-03 Farmitalia Carlo Erba S.P.A. 3-(1-Imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran
GB2071655B (en) * 1980-03-04 1983-06-22 Erba Farmitalia N-amidazolyl derivatives of1-chroman and process for their preparation
ZA81980B (en) * 1980-03-04 1982-02-24 Erba Farmitalia N-imidazolyl derivatives of 1-chroman and process for their preparation
IL66242A0 (en) * 1981-07-23 1982-11-30 Erba Farmitalia N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene,indan and 2-substituted-1-chroman,their preparation and pharmaceutical compositions containing them
ZA825142B (en) * 1981-07-23 1983-04-27 Erba Farmitalia N-imidazolyl derivatives of 1,2,3,j-tetrahydro-naphthalene, indan and 2-substituted-1-chroman, and process for their preparation
ZA825413B (en) * 1981-08-26 1983-06-29 Pfizer Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them
JPS6081566A (ja) * 1983-10-07 1985-05-09 Nissan Motor Co Ltd ロツクアツプトルクコンバ−タのスリツプ制御装置

Also Published As

Publication number Publication date
US4602022A (en) 1986-07-22
FR2529547B1 (fr) 1986-09-05
SE461791B (sv) 1990-03-26
FI74466C (fi) 1988-02-08
NZ204802A (en) 1986-04-11
NO832437L (no) 1984-01-06
ES8503669A1 (es) 1985-03-01
DK307983A (da) 1984-01-06
SG73487G (en) 1988-03-04
SE8303824D0 (sv) 1983-07-04
JPS5927874A (ja) 1984-02-14
FR2529547A1 (fr) 1984-01-06
ATA247383A (de) 1987-12-15
BE897207A (fr) 1984-01-04
DE3324069C2 (de) 1994-08-25
CH655102A5 (de) 1986-03-27
CZ413491A3 (en) 1993-10-13
NO161439C (no) 1989-08-16
PT76979A (en) 1983-08-01
IT8321886A0 (it) 1983-07-01
YU144283A (en) 1986-10-31
KR910000414B1 (ko) 1991-01-25
HU193529B (en) 1987-10-28
IE831564L (en) 1984-01-05
AT386201B (de) 1988-07-25
DK307983D0 (da) 1983-07-04
FI74466B (fi) 1987-10-30
DE3324069A1 (de) 1984-01-26
NO161439B (no) 1989-05-08
NL8302347A (nl) 1984-02-01
HK101187A (en) 1988-01-08
GR77577B (da) 1984-09-24
SU1342414A3 (ru) 1987-09-30
AU557304B2 (en) 1986-12-18
IL69152A0 (en) 1983-11-30
ES523609A0 (es) 1985-03-01
KR840005433A (ko) 1984-11-12
DK163359B (da) 1992-02-24
FI832420A0 (fi) 1983-07-01
IT1163641B (it) 1987-04-08
FI832420L (fi) 1984-01-06
CS509483A2 (en) 1990-08-14
SE8303824L (sv) 1984-01-06
LU84895A1 (fr) 1983-11-23
CS273310B2 (en) 1991-03-12
YU43545B (en) 1989-08-31
JPH0454662B2 (da) 1992-08-31
ZA834865B (en) 1984-03-28
US4510149A (en) 1985-04-09
IE55894B1 (en) 1991-02-14
AU1654083A (en) 1984-01-12
PH21115A (en) 1987-07-16
PT76979B (en) 1986-01-09
MY104376A (en) 1994-03-31
CA1202030A (en) 1986-03-18

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