ES409089A1 - Procedimiento para la preparacion de nuevas 6-aza-3h-1,4- benzodiazepinas. - Google Patents

Procedimiento para la preparacion de nuevas 6-aza-3h-1,4- benzodiazepinas.

Info

Publication number
ES409089A1
ES409089A1 ES409089A ES409089A ES409089A1 ES 409089 A1 ES409089 A1 ES 409089A1 ES 409089 A ES409089 A ES 409089A ES 409089 A ES409089 A ES 409089A ES 409089 A1 ES409089 A1 ES 409089A1
Authority
ES
Spain
Prior art keywords
group
molecular weight
low molecular
atom
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES409089A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Deutsche Gold und Silber Scheideanstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH, Deutsche Gold und Silber Scheideanstalt filed Critical Degussa GmbH
Publication of ES409089A1 publication Critical patent/ES409089A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
ES409089A 1971-12-09 1972-11-29 Procedimiento para la preparacion de nuevas 6-aza-3h-1,4- benzodiazepinas. Expired ES409089A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1060471A AT333284B (de) 1971-12-09 1971-12-09 Verfahren zur herstellung von neuen 6-aza-3h-1,4-benzodiazepinen, deren optischen isomeren und deren salzen

Publications (1)

Publication Number Publication Date
ES409089A1 true ES409089A1 (es) 1975-10-16

Family

ID=3623479

Family Applications (2)

Application Number Title Priority Date Filing Date
ES409090A Expired ES409090A1 (es) 1971-12-09 1972-11-29 Procedimiento para la preparacion de nuevas 6-aza-3h-1,4- benzodiazepinas.
ES409089A Expired ES409089A1 (es) 1971-12-09 1972-11-29 Procedimiento para la preparacion de nuevas 6-aza-3h-1,4- benzodiazepinas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES409090A Expired ES409090A1 (es) 1971-12-09 1972-11-29 Procedimiento para la preparacion de nuevas 6-aza-3h-1,4- benzodiazepinas.

Country Status (26)

Country Link
JP (4) JPS569509B2 (fr)
AR (3) AR201201A1 (fr)
AT (4) AT332878B (fr)
AU (1) AU473253B2 (fr)
BE (1) BE792541A (fr)
CH (4) CH594665A5 (fr)
CS (1) CS212736B2 (fr)
DD (1) DD105448A5 (fr)
DE (1) DE2259471C2 (fr)
DK (1) DK138425B (fr)
EG (1) EG10918A (fr)
ES (2) ES409090A1 (fr)
FI (1) FI54710C (fr)
FR (1) FR2162482B1 (fr)
GB (1) GB1400755A (fr)
HU (1) HU169468B (fr)
IL (1) IL41034A (fr)
IT (1) IT1035053B (fr)
NL (1) NL171986C (fr)
NO (1) NO137094C (fr)
PL (3) PL91828B1 (fr)
RO (4) RO65263A (fr)
SE (1) SE404803B (fr)
SU (4) SU468423A3 (fr)
YU (2) YU305972A (fr)
ZA (1) ZA728497B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2364636C2 (de) * 1973-12-24 1982-11-04 Degussa Ag, 6000 Frankfurt Verfahren zur Herstellung von 2-Benzoyl-6-chlor-3-nitro-pyridinen
DE3067662D1 (en) * 1980-01-16 1984-06-07 Lacer Sa New 2-halo-pyridines, their production and pharmaceutical compositions
JPS60132610A (ja) * 1983-12-20 1985-07-15 Japan Organo Co Ltd 汚泥脱水装置
JPS6219221A (ja) * 1985-07-16 1987-01-28 Chiyoda Chem Eng & Constr Co Ltd 原液中の微細粒子を除去する濾過方法と濾過装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314941A (en) * 1964-06-23 1967-04-18 American Cyanamid Co Novel substituted pyridodiazepins
US3523939A (en) * 1967-07-03 1970-08-11 Hoffmann La Roche 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation

Also Published As

Publication number Publication date
SU468423A3 (ru) 1975-04-25
ATA902174A (de) 1976-02-15
ES409090A1 (es) 1975-10-16
DE2259471C2 (de) 1982-08-19
JPS55147282A (en) 1980-11-17
FI54710C (fi) 1979-02-12
NO137094B (no) 1977-09-19
SU674675A3 (ru) 1979-07-15
AT332877B (de) 1976-10-25
NL7216621A (fr) 1973-06-13
NL171986B (nl) 1983-01-17
RO65263A (fr) 1983-07-07
AT332878B (de) 1976-10-25
RO62312A (fr) 1977-12-15
JPS5744678B2 (fr) 1982-09-22
AU473253B2 (en) 1976-06-17
PL91876B1 (en) 1977-03-31
PL91828B1 (en) 1977-03-31
RO65264A (fr) 1979-08-15
AT333284B (de) 1976-11-10
CH603645A5 (fr) 1978-08-31
ZA728497B (en) 1973-09-26
AT338798B (de) 1977-09-12
JPS5742639B2 (fr) 1982-09-09
DK138425C (fr) 1979-02-12
AU4993172A (en) 1974-06-13
RO65263B (ro) 1983-06-30
JPS4864096A (fr) 1973-09-05
JPS5625181A (en) 1981-03-10
CH594665A5 (fr) 1978-01-13
BE792541A (fr) 1973-06-08
ATA902074A (de) 1977-01-15
YU116881A (en) 1984-02-29
GB1400755A (en) 1975-07-23
RO67345A (fr) 1980-07-15
FI54710B (fi) 1978-10-31
NO137094C (no) 1977-12-28
CH603644A5 (fr) 1978-08-31
SU564809A3 (ru) 1977-07-05
HU169468B (fr) 1976-11-28
JPS5625180A (en) 1981-03-10
IL41034A0 (en) 1973-02-28
ATA1060471A (de) 1976-03-15
DE2259471A1 (de) 1973-06-14
FR2162482A1 (fr) 1973-07-20
YU305972A (en) 1982-02-28
CH605946A5 (fr) 1978-10-13
IT1035053B (it) 1979-10-20
PL89682B1 (en) 1976-12-31
CS212736B2 (en) 1982-03-26
DK138425B (da) 1978-09-04
ATA902274A (de) 1976-02-15
JPS569509B2 (fr) 1981-03-02
IL41034A (en) 1976-10-31
SE404803B (sv) 1978-10-30
AR201201A1 (es) 1975-02-21
FR2162482B1 (fr) 1976-03-05
AR200309A1 (es) 1974-10-31
SU574156A3 (ru) 1977-09-25
EG10918A (en) 1981-12-31
AR203311A1 (es) 1975-08-29
NL171986C (nl) 1983-06-16
JPS5742638B2 (fr) 1982-09-09
DD105448A5 (fr) 1974-04-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19880204