ES387562A1 - Procedimiento de 1,4-dihidropiridinas con efecto dilatador de los vasos coronarios. - Google Patents

Procedimiento de 1,4-dihidropiridinas con efecto dilatador de los vasos coronarios.

Info

Publication number
ES387562A1
ES387562A1 ES387562A ES387562A ES387562A1 ES 387562 A1 ES387562 A1 ES 387562A1 ES 387562 A ES387562 A ES 387562A ES 387562 A ES387562 A ES 387562A ES 387562 A1 ES387562 A1 ES 387562A1
Authority
ES
Spain
Prior art keywords
formula
radical
general formula
carbon atoms
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES387562A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES387562A1 publication Critical patent/ES387562A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ES387562A 1970-01-24 1971-01-23 Procedimiento de 1,4-dihidropiridinas con efecto dilatador de los vasos coronarios. Expired ES387562A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702003146 DE2003146A1 (de) 1970-01-24 1970-01-24 Neue 1,4-Dihydropyridinderivate

Publications (1)

Publication Number Publication Date
ES387562A1 true ES387562A1 (es) 1974-01-01

Family

ID=5760409

Family Applications (1)

Application Number Title Priority Date Filing Date
ES387562A Expired ES387562A1 (es) 1970-01-24 1971-01-23 Procedimiento de 1,4-dihidropiridinas con efecto dilatador de los vasos coronarios.

Country Status (15)

Country Link
US (1) US3775422A (es)
AT (2) AT306720B (es)
BE (1) BE761929A (es)
CA (1) CA945167A (es)
CH (1) CH586200A5 (es)
CS (2) CS163747B2 (es)
DE (1) DE2003146A1 (es)
ES (1) ES387562A1 (es)
FR (1) FR2081452B1 (es)
GB (1) GB1317425A (es)
HU (1) HU162199B (es)
IE (1) IE34890B1 (es)
IL (1) IL35924A (es)
NL (1) NL7100816A (es)
ZA (1) ZA7152B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1430961A (en) * 1972-01-22 1976-04-07 Yamanouchi Pharma Co Ltd 1-substituted-1,4-dihyddrypyridine derivatives
DD106832A5 (es) * 1972-03-06 1974-07-05
US4001258A (en) * 1972-03-06 1977-01-04 Bayer Aktiengesellschaft 2-amino-1,4-dihydropyridine derivatives
DE2210674C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
US3935223A (en) * 1972-03-06 1976-01-27 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
US3939171A (en) * 1972-03-06 1976-02-17 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
US3857849A (en) * 1973-02-28 1974-12-31 Bayer Ag 2-amino-1,4-dihydropyridine derivatives
US3988458A (en) * 1972-03-06 1976-10-26 Bayer Aktiengesellschaft Bicyclic derivatives of 1,4-dihydropyridine 3,5-carboxylic acid esters
US3917622A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-1,4-dihydropyridine derivatives
US3887558A (en) * 1972-03-06 1975-06-03 Bayer Ag Process for producing 2,6-diamino -1,4- dihydro-3,5-pyridine-dicarboxylates and derivatives thereof
US3985886A (en) * 1972-03-06 1976-10-12 Bayer Aktiengesellschaft 2-Amino-4,5-dihydropyridine derivatives and process for their preparation
US3917620A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
US3917619A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
US3957998A (en) * 1972-03-06 1976-05-18 Bayer Aktiengesellschaft Use of 2,6-diamino-4-substituted-1,4-dihydropyridine-3,5-dicarboxylic acid esters for effecting coronary vessel dilation and treating hypertension
US3992545A (en) * 1972-03-06 1976-11-16 Bayer Aktiengesellschaft 2-Amino-4,5-dihydropyridine derivatives in pharmaceutical compositions
US3968117A (en) * 1972-06-10 1976-07-06 Bayer Aktiengesellschaft 1,4-Dihydropyridines
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2242787C2 (de) * 1972-08-31 1982-01-21 Bayer Ag, 5090 Leverkusen 4-Phenyl-6-amino-3,4-dihydropyridon-(2)-3,5-dicarbonsäure-diäthylesterderivate, ein Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2242786A1 (de) * 1972-08-31 1974-03-14 Bayer Ag Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel
US3989708A (en) * 1972-08-31 1976-11-02 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
US4002762A (en) * 1973-03-03 1977-01-11 Bayer Aktiengesellschaft 2-Amino-3,4-dihydropyridines used to effect coronary vessel dilation and treat hypertension
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
DE3021958A1 (de) * 1980-06-12 1981-12-24 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
US4497808A (en) * 1981-12-30 1985-02-05 Ciba-Geigy Corporation N-Oxide compounds useful in the treatment of cardiovascular ailments
US4529733A (en) * 1983-04-06 1985-07-16 Merrell Dow Pharmaceuticals Inc. Antihypertensive 3-furoyl-1,4-dihydropyridines
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
US4994476A (en) * 1984-10-31 1991-02-19 Bristol-Myers Company Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
JPS6289662A (ja) * 1985-06-14 1987-04-24 Sankyo Co Ltd １，４−ジヒドロピリジン誘導体
US4772596A (en) * 1986-10-09 1988-09-20 Sankyo Company Limited Dihydropyridine derivatives, their preparation and their use
DE4118707A1 (de) * 1991-06-07 1992-12-10 Bayer Ag Pharmazeutische verwendung von 3-formyl-1,4-dihydropyridinen, neue verbindungen und verfahren zu ihrer herstellung
DE102005034267A1 (de) 2005-07-22 2007-01-25 Bayer Healthcare Ag 4-Chromenonyl-1,4-dihydropyridine und ihre Verwendung
DE102005034264A1 (de) 2005-07-22 2007-02-01 Bayer Healthcare Ag 4-Chromenonyl-1,4-dihydropyridincarbonitrile und ihre Verwendung
US9828344B2 (en) 2012-06-01 2017-11-28 LEIBNIZ-INSTITUT FÜR ALTERSFORSCHUNG FRITZ-LIPMANN-INSTITUT e.V. (FLI) Inhibitors of the notch signaling pathway and secretion for use in medicine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455939A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(4-chloro-3-sulfamoylphenyl)-1,4-dihydropyridines

Also Published As

Publication number Publication date
NL7100816A (es) 1971-07-27
FR2081452A1 (es) 1971-12-03
AT304552B (de) 1973-01-10
CS163748B2 (es) 1975-11-07
IE34890L (en) 1971-07-24
AT306720B (de) 1973-04-25
GB1317425A (en) 1973-05-16
IE34890B1 (en) 1975-09-17
IL35924A (en) 1974-09-10
CA945167A (en) 1974-04-09
IL35924A0 (en) 1971-02-25
CS163747B2 (es) 1975-11-07
ZA7152B (en) 1971-10-27
BE761929A (es) 1971-07-22
HU162199B (es) 1973-01-29
SU383290A3 (es) 1973-05-25
SU379091A3 (es) 1973-04-18
CH586200A5 (es) 1977-03-31
FR2081452B1 (es) 1974-08-23
DE2003146A1 (de) 1971-07-29
US3775422A (en) 1973-11-27

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