IT1035053B - Procedimento per la produzione di aza 3h i.4 benzodiazepine - Google Patents
Procedimento per la produzione di aza 3h i.4 benzodiazepineInfo
- Publication number
- IT1035053B IT1035053B IT7254583Q IT5458372Q IT1035053B IT 1035053 B IT1035053 B IT 1035053B IT 7254583 Q IT7254583 Q IT 7254583Q IT 5458372 Q IT5458372 Q IT 5458372Q IT 1035053 B IT1035053 B IT 1035053B
- Authority
- IT
- Italy
- Prior art keywords
- benzodiazepine
- aza
- procedure
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT1060471A AT333284B (de) | 1971-12-09 | 1971-12-09 | Verfahren zur herstellung von neuen 6-aza-3h-1,4-benzodiazepinen, deren optischen isomeren und deren salzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1035053B true IT1035053B (it) | 1979-10-20 |
Family
ID=3623479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT7254583Q IT1035053B (it) | 1971-12-09 | 1972-12-07 | Procedimento per la produzione di aza 3h i.4 benzodiazepine |
Country Status (26)
| Country | Link |
|---|---|
| JP (4) | JPS569509B2 (it) |
| AR (3) | AR201201A1 (it) |
| AT (4) | AT332877B (it) |
| AU (1) | AU473253B2 (it) |
| BE (1) | BE792541A (it) |
| CH (4) | CH594665A5 (it) |
| CS (1) | CS212736B2 (it) |
| DD (1) | DD105448A5 (it) |
| DE (1) | DE2259471C2 (it) |
| DK (1) | DK138425B (it) |
| EG (1) | EG10918A (it) |
| ES (2) | ES409090A1 (it) |
| FI (1) | FI54710C (it) |
| FR (1) | FR2162482B1 (it) |
| GB (1) | GB1400755A (it) |
| HU (1) | HU169468B (it) |
| IL (1) | IL41034A (it) |
| IT (1) | IT1035053B (it) |
| NL (1) | NL171986C (it) |
| NO (1) | NO137094C (it) |
| PL (3) | PL91828B1 (it) |
| RO (4) | RO67345A (it) |
| SE (1) | SE404803B (it) |
| SU (4) | SU468423A3 (it) |
| YU (2) | YU305972A (it) |
| ZA (1) | ZA728497B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2364636C2 (de) * | 1973-12-24 | 1982-11-04 | Degussa Ag, 6000 Frankfurt | Verfahren zur Herstellung von 2-Benzoyl-6-chlor-3-nitro-pyridinen |
| ATE7295T1 (de) * | 1980-01-16 | 1984-05-15 | Lacer, S.A. | 2-halo-pyridine, ihre herstellung und pharmazeutische zusammensetzungen. |
| JPS60132610A (ja) * | 1983-12-20 | 1985-07-15 | Japan Organo Co Ltd | 汚泥脱水装置 |
| JPS6219221A (ja) * | 1985-07-16 | 1987-01-28 | Chiyoda Chem Eng & Constr Co Ltd | 原液中の微細粒子を除去する濾過方法と濾過装置 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3314941A (en) * | 1964-06-23 | 1967-04-18 | American Cyanamid Co | Novel substituted pyridodiazepins |
| US3523939A (en) * | 1967-07-03 | 1970-08-11 | Hoffmann La Roche | 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation |
-
1971
- 1971-12-09 AT AT902174A patent/AT332877B/de active
- 1971-12-09 AT AT902274A patent/AT332878B/de active
- 1971-12-09 AT AT1060471A patent/AT333284B/de not_active IP Right Cessation
-
1972
- 1972-11-29 ES ES409090A patent/ES409090A1/es not_active Expired
- 1972-11-29 ES ES409089A patent/ES409089A1/es not_active Expired
- 1972-11-30 ZA ZA728497A patent/ZA728497B/xx unknown
- 1972-11-30 FI FI3390/72A patent/FI54710C/fi active
- 1972-12-05 SE SE7215858A patent/SE404803B/xx unknown
- 1972-12-05 DE DE2259471A patent/DE2259471C2/de not_active Expired
- 1972-12-06 EG EG502/72A patent/EG10918A/xx active
- 1972-12-06 FR FR7243359A patent/FR2162482B1/fr not_active Expired
- 1972-12-06 HU HUDE799A patent/HU169468B/hu unknown
- 1972-12-07 IT IT7254583Q patent/IT1035053B/it active
- 1972-12-07 RO RO7281197A patent/RO67345A/ro unknown
- 1972-12-07 RO RO7281195A patent/RO65264A/ro unknown
- 1972-12-07 PL PL1972175582A patent/PL91828B1/pl unknown
- 1972-12-07 PL PL1972159365A patent/PL89682B1/pl unknown
- 1972-12-07 NL NLAANVRAGE7216621,A patent/NL171986C/xx not_active IP Right Cessation
- 1972-12-07 PL PL1972175581A patent/PL91876B1/pl unknown
- 1972-12-07 RO RO7200073075A patent/RO62312A/ro unknown
- 1972-12-07 RO RO7281196A patent/RO65263A/ro unknown
- 1972-12-08 DK DK615172AA patent/DK138425B/da not_active IP Right Cessation
- 1972-12-08 NO NO4536/72A patent/NO137094C/no unknown
- 1972-12-08 CS CS728424A patent/CS212736B2/cs unknown
- 1972-12-08 IL IL41034A patent/IL41034A/en unknown
- 1972-12-08 YU YU03059/72A patent/YU305972A/xx unknown
- 1972-12-08 GB GB5688372A patent/GB1400755A/en not_active Expired
- 1972-12-08 BE BE792541A patent/BE792541A/xx not_active IP Right Cessation
- 1972-12-08 SU SU1855103A patent/SU468423A3/ru active
- 1972-12-09 JP JP12387872A patent/JPS569509B2/ja not_active Expired
- 1972-12-11 AU AU49931/72A patent/AU473253B2/en not_active Expired
- 1972-12-11 CH CH1794972A patent/CH594665A5/xx not_active IP Right Cessation
- 1972-12-11 DD DD167428A patent/DD105448A5/xx unknown
- 1972-12-11 CH CH1506576A patent/CH605946A5/xx not_active IP Right Cessation
- 1972-12-11 CH CH1526076A patent/CH603645A5/xx not_active IP Right Cessation
- 1972-12-11 CH CH1506676A patent/CH603644A5/xx not_active IP Right Cessation
-
1973
- 1973-09-10 AR AR250008A patent/AR201201A1/es active
-
1974
- 1974-03-20 AR AR252867A patent/AR200309A1/es active
- 1974-07-08 SU SU7402042686A patent/SU564809A3/ru active
- 1974-07-08 SU SU742041603A patent/SU674675A3/ru active
- 1974-10-15 SU SU7402067128A patent/SU574156A3/ru active
- 1974-10-31 AR AR256352A patent/AR203311A1/es active
- 1974-11-11 AT AT902074A patent/AT338798B/de not_active IP Right Cessation
-
1980
- 1980-04-15 JP JP5022180A patent/JPS5625180A/ja active Granted
- 1980-04-15 JP JP5022280A patent/JPS55147282A/ja active Granted
- 1980-04-15 JP JP5022380A patent/JPS5625181A/ja active Granted
-
1981
- 1981-05-07 YU YU01168/81A patent/YU116881A/xx unknown
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