YU305972A - Process for producing 2-halo-9-phenyl-5,6-dihydro-7h-pyridprocess for obtaining new ergoline derivatives o(2,3,f)-(1,4)diazepine derivatives - Google Patents

Process for producing 2-halo-9-phenyl-5,6-dihydro-7h-pyridprocess for obtaining new ergoline derivatives o(2,3,f)-(1,4)diazepine derivatives

Info

Publication number
YU305972A
YU305972A YU03059/72A YU305972A YU305972A YU 305972 A YU305972 A YU 305972A YU 03059/72 A YU03059/72 A YU 03059/72A YU 305972 A YU305972 A YU 305972A YU 305972 A YU305972 A YU 305972A
Authority
YU
Yugoslavia
Prior art keywords
derivatives
pyridprocess
dihydro
halo
phenyl
Prior art date
Application number
YU03059/72A
Other languages
English (en)
Inventor
Bebenburg W Von
G Arcari
H Offermanns
L Bernardi
M Foglio
A Glaesser
A Temperilli
Original Assignee
Degussa
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa, Farmaceutici Italia filed Critical Degussa
Publication of YU305972A publication Critical patent/YU305972A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
YU03059/72A 1971-12-09 1972-12-08 Process for producing 2-halo-9-phenyl-5,6-dihydro-7h-pyridprocess for obtaining new ergoline derivatives o(2,3,f)-(1,4)diazepine derivatives YU305972A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1060471A AT333284B (de) 1971-12-09 1971-12-09 Verfahren zur herstellung von neuen 6-aza-3h-1,4-benzodiazepinen, deren optischen isomeren und deren salzen

Publications (1)

Publication Number Publication Date
YU305972A true YU305972A (en) 1982-02-28

Family

ID=3623479

Family Applications (2)

Application Number Title Priority Date Filing Date
YU03059/72A YU305972A (en) 1971-12-09 1972-12-08 Process for producing 2-halo-9-phenyl-5,6-dihydro-7h-pyridprocess for obtaining new ergoline derivatives o(2,3,f)-(1,4)diazepine derivatives
YU01168/81A YU116881A (en) 1971-12-09 1981-05-07 Process for producing new 6-aza-3h-1,4-benzodiazepines

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU01168/81A YU116881A (en) 1971-12-09 1981-05-07 Process for producing new 6-aza-3h-1,4-benzodiazepines

Country Status (26)

Country Link
JP (4) JPS569509B2 (xx)
AR (3) AR201201A1 (xx)
AT (4) AT332877B (xx)
AU (1) AU473253B2 (xx)
BE (1) BE792541A (xx)
CH (4) CH594665A5 (xx)
CS (1) CS212736B2 (xx)
DD (1) DD105448A5 (xx)
DE (1) DE2259471C2 (xx)
DK (1) DK138425B (xx)
EG (1) EG10918A (xx)
ES (2) ES409090A1 (xx)
FI (1) FI54710C (xx)
FR (1) FR2162482B1 (xx)
GB (1) GB1400755A (xx)
HU (1) HU169468B (xx)
IL (1) IL41034A (xx)
IT (1) IT1035053B (xx)
NL (1) NL171986C (xx)
NO (1) NO137094C (xx)
PL (3) PL91876B1 (xx)
RO (4) RO65263A (xx)
SE (1) SE404803B (xx)
SU (4) SU468423A3 (xx)
YU (2) YU305972A (xx)
ZA (1) ZA728497B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2364636C2 (de) * 1973-12-24 1982-11-04 Degussa Ag, 6000 Frankfurt Verfahren zur Herstellung von 2-Benzoyl-6-chlor-3-nitro-pyridinen
EP0032516B1 (en) * 1980-01-16 1984-05-02 Lacer, S.A. New 2-halo-pyridines, their production and pharmaceutical compositions
JPS60132610A (ja) * 1983-12-20 1985-07-15 Japan Organo Co Ltd 汚泥脱水装置
JPS6219221A (ja) * 1985-07-16 1987-01-28 Chiyoda Chem Eng & Constr Co Ltd 原液中の微細粒子を除去する濾過方法と濾過装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3314941A (en) * 1964-06-23 1967-04-18 American Cyanamid Co Novel substituted pyridodiazepins
US3523939A (en) * 1967-07-03 1970-08-11 Hoffmann La Roche 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation

Also Published As

Publication number Publication date
SU468423A3 (ru) 1975-04-25
PL91828B1 (en) 1977-03-31
JPS5742638B2 (xx) 1982-09-09
ZA728497B (en) 1973-09-26
PL91876B1 (en) 1977-03-31
DE2259471C2 (de) 1982-08-19
GB1400755A (en) 1975-07-23
RO67345A (ro) 1980-07-15
FR2162482B1 (xx) 1976-03-05
SU564809A3 (ru) 1977-07-05
JPS569509B2 (xx) 1981-03-02
RO65264A (fr) 1979-08-15
NL171986C (nl) 1983-06-16
BE792541A (fr) 1973-06-08
SU574156A3 (ru) 1977-09-25
FI54710B (fi) 1978-10-31
IL41034A0 (en) 1973-02-28
CH603645A5 (xx) 1978-08-31
JPS5742639B2 (xx) 1982-09-09
AU473253B2 (en) 1976-06-17
JPS4864096A (xx) 1973-09-05
IL41034A (en) 1976-10-31
JPS5625181A (en) 1981-03-10
ATA1060471A (de) 1976-03-15
HU169468B (xx) 1976-11-28
AT332877B (de) 1976-10-25
YU116881A (en) 1984-02-29
ES409089A1 (es) 1975-10-16
PL89682B1 (en) 1976-12-31
RO65263B (ro) 1983-06-30
DD105448A5 (xx) 1974-04-20
AT332878B (de) 1976-10-25
AT338798B (de) 1977-09-12
SU674675A3 (ru) 1979-07-15
CS212736B2 (en) 1982-03-26
ATA902174A (de) 1976-02-15
CH603644A5 (xx) 1978-08-31
JPS5625180A (en) 1981-03-10
CH594665A5 (xx) 1978-01-13
DK138425B (da) 1978-09-04
ATA902274A (de) 1976-02-15
SE404803B (sv) 1978-10-30
AT333284B (de) 1976-11-10
DE2259471A1 (de) 1973-06-14
NL171986B (nl) 1983-01-17
ATA902074A (de) 1977-01-15
JPS55147282A (en) 1980-11-17
CH605946A5 (xx) 1978-10-13
FR2162482A1 (xx) 1973-07-20
RO62312A (fr) 1977-12-15
NO137094C (no) 1977-12-28
AR203311A1 (es) 1975-08-29
JPS5744678B2 (xx) 1982-09-22
NL7216621A (xx) 1973-06-13
DK138425C (xx) 1979-02-12
AR200309A1 (es) 1974-10-31
FI54710C (fi) 1979-02-12
EG10918A (en) 1981-12-31
AR201201A1 (es) 1975-02-21
IT1035053B (it) 1979-10-20
AU4993172A (en) 1974-06-13
NO137094B (no) 1977-09-19
ES409090A1 (es) 1975-10-16
RO65263A (ro) 1983-07-07

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