ES2963157T3 - Anticuerpos anti-SIRP-alfa y métodos relacionados - Google Patents
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| US201762537207P | 2017-07-26 | 2017-07-26 | |
| PCT/US2018/043699 WO2019023347A1 (en) | 2017-07-26 | 2018-07-25 | ANTI-SIRP-ALPHA ANTIBODIES AND ASSOCIATED METHODS |
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| US20170151281A1 (en) | 2015-02-19 | 2017-06-01 | Batu Biologics, Inc. | Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer |
| US10927173B2 (en) | 2016-01-11 | 2021-02-23 | Forty Seven, Inc. | Humanized, mouse or chimeric anti-CD47 monoclonal antibodies |
| MX2018012434A (es) | 2016-04-14 | 2019-06-06 | Ose Immunotherapeutics | Nuevos anticuerpos anti-sirpa y sus aplicaciones terapeuticas. |
| JOP20190009A1 (ar) | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
| CN118027200A (zh) | 2016-12-09 | 2024-05-14 | 艾利妥 | 抗SIRPα抗体及其使用方法 |
| TW202430219A (zh) | 2017-04-13 | 2024-08-01 | 荷蘭商賽羅帕公司 | 抗-SIRPα 抗體 |
| AU2018308364C1 (en) | 2017-07-26 | 2023-02-16 | Forty Seven, LLC | Anti-SIRP-alpha antibodies and related methods |
| EP3752190B1 (en) | 2018-02-12 | 2022-07-06 | Forty Seven, Inc. | Anti-cancer regimen using anti-cd47 and anti-cd20 antibodies |
| CN118344481A (zh) | 2018-03-21 | 2024-07-16 | Alx肿瘤生物技术公司 | 针对信号调控蛋白α的抗体和使用方法 |
| CN110386984B (zh) * | 2018-04-17 | 2022-04-22 | 杭州尚健生物技术有限公司 | 结合cd47蛋白的融合蛋白及其应用 |
| CN112534054B (zh) | 2018-05-11 | 2025-10-28 | 比姆医疗股份有限公司 | 使用可编程碱基编辑器系统取代病原性氨基酸的方法 |
| CR20200566A (es) | 2018-05-25 | 2021-02-19 | Alector Llc | Anticuerpos anti-sirpa y metodos de utilización de los mismos |
| US11591390B2 (en) | 2018-09-27 | 2023-02-28 | Celgene Corporation | SIRP-α binding proteins and methods of use thereof |
| MX2021003393A (es) | 2018-09-27 | 2021-05-13 | Celgene Corp | Proteinas de fijacion a sirp alfa y metodos de uso de estas. |
| EP3876977A1 (en) | 2018-11-06 | 2021-09-15 | The Regents Of The University Of California | Chimeric antigen receptors for phagocytosis |
| JP7451520B2 (ja) | 2018-11-15 | 2024-03-18 | ビョンディス・ビー．ブイ． | ヒト化抗ＳＩＲＰα抗体 |
| MY205760A (en) | 2018-11-26 | 2024-11-12 | Forty Seven Inc | Humanized antibodies against c-kit |
| US11013764B2 (en) | 2019-04-30 | 2021-05-25 | Myeloid Therapeutics, Inc. | Engineered phagocytic receptor compositions and methods of use thereof |
| KR20220012328A (ko) * | 2019-05-24 | 2022-02-03 | 포티 세븐, 인코포레이티드 | c-kit 및 CD47에 대한 면역요법제의 병용 투여를 위한 요법 |
| JP7561775B2 (ja) | 2019-06-07 | 2024-10-04 | エーエルエックス オンコロジー インコーポレイテッド | 血清学的アッセイにおいてｃｄ４７に結合する薬物の干渉を低減するための方法及び試薬 |
| MX2021015452A (es) | 2019-06-25 | 2022-02-11 | Gilead Sciences Inc | Proteinas de fusion flt3l-fc y metodos de uso. |
| WO2021022044A1 (en) * | 2019-07-31 | 2021-02-04 | Forty Seven, Inc. | Depletion regimes for engineered t-cell or nk-cell therapy |
| JP2022545300A (ja) * | 2019-08-20 | 2022-10-27 | エルピサイエンス（スーチョウ）・バイオファーマ，リミテッド | 新規の抗ｓｉｒｐａ抗体 |
| GB2605276B (en) | 2019-09-03 | 2024-08-07 | Myeloid Therapeutics Inc | Methods and compositions for genomic integration |
| CA3153501A1 (en) | 2019-10-18 | 2021-04-22 | Forty Seven, Inc. | Combination therapies for treating myelodysplastic syndromes and acute myeloid leukemia |
| WO2021087064A1 (en) | 2019-10-31 | 2021-05-06 | Forty Seven, Inc. | Anti-cd47 and anti-cd20 based treatment of blood cancer |
| AU2020394204A1 (en) | 2019-11-27 | 2022-06-02 | ALX Oncology Inc. | Combination therapies for treating cancer |
| US10980836B1 (en) | 2019-12-11 | 2021-04-20 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods of manufacturing and use thereof |
| JP7437815B2 (ja) * | 2019-12-24 | 2024-02-26 | ラノバ メディシンズ リミテッド | 抗ＳＩＲＰαモノクローナル抗体およびその使用 |
| EP4445902A3 (en) | 2019-12-24 | 2024-12-18 | Carna Biosciences, Inc. | Diacylglycerol kinase modulating compounds |
| MX2022009947A (es) | 2020-02-14 | 2022-11-07 | Jounce Therapeutics Inc | Anticuerpos y proteinas de fusion que se unen a ccr8 y usos de estos. |
| US12146000B2 (en) | 2020-05-19 | 2024-11-19 | Boehringer Ingelheim International Gmbh | Bispecific and tetravalent CD137 and FAP molecules for the treatment of cancer |
| CN115666620A (zh) | 2020-06-01 | 2023-01-31 | Alx肿瘤生物技术公司 | 用于治疗癌症的包含低甲基化剂的联合疗法 |
| CN115885044A (zh) * | 2020-09-04 | 2023-03-31 | 江苏恒瑞医药股份有限公司 | SIRPγ变体及其融合蛋白 |
| TWI815194B (zh) | 2020-10-22 | 2023-09-11 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
| JP2023550544A (ja) | 2020-11-03 | 2023-12-01 | アールディスカバリー エルエルシー | がんおよびファゴサイトーシス不全に関連する疾患の処置のための療法 |
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| EP4253416A4 (en) * | 2020-11-30 | 2024-11-13 | Qure Biotechnology (Shanghai) Co., Ltd. | ANTI-SIRPALPHA ANTIBODY OR ASSOCIATED ANTIGEN-BINDING FRAGMENT, AND USE THEREOF |
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| CN112574310B (zh) * | 2020-12-11 | 2023-05-05 | 浙江博锐生物制药有限公司 | 抗SIRPα抗体及其用途 |
| TW202302145A (zh) | 2021-04-14 | 2023-01-16 | 美商基利科學股份有限公司 | ＣＤ４７／ＳＩＲＰα結合及ＮＥＤＤ８活化酶Ｅ１調節次單元之共抑制以用於治療癌症 |
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| WO2016205042A1 (en) | 2015-06-16 | 2016-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | SIRPα AGONIST ANTIBODY |
| JP7078533B2 (ja) * | 2015-10-21 | 2022-05-31 | オーエスイー イムノセラピューティクス | 炎症促進性細胞へのマクロファージ分極を改変して癌を治療するための抗ＳＩＲＰａ化合物 |
| US10927173B2 (en) | 2016-01-11 | 2021-02-23 | Forty Seven, Inc. | Humanized, mouse or chimeric anti-CD47 monoclonal antibodies |
| MX2018012434A (es) * | 2016-04-14 | 2019-06-06 | Ose Immunotherapeutics | Nuevos anticuerpos anti-sirpa y sus aplicaciones terapeuticas. |
| WO2018026600A1 (en) | 2016-08-03 | 2018-02-08 | The Board Of Trustees Of The Leland Stanford Junior University | Disrupting fc receptor engagement on macrophages enhances efficacy of anti-sirpalpha antibody therapy |
| AU2018308364C1 (en) | 2017-07-26 | 2023-02-16 | Forty Seven, LLC | Anti-SIRP-alpha antibodies and related methods |
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| EP3658589A1 (en) | 2020-06-03 |
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| CN111448210B (zh) | 2024-05-14 |
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| AU2018308364C1 (en) | 2023-02-16 |
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| US11753480B2 (en) | 2023-09-12 |
| CN111448210A (zh) | 2020-07-24 |
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| IL272218A (en) | 2020-03-31 |
| SG11202000658PA (en) | 2020-02-27 |
| EP3658589B1 (en) | 2023-09-27 |
| PL3658589T3 (pl) | 2024-03-18 |
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