ES2868249T3 - Proceso de purificación de un oligosacárido de leche humana neutro mediante cromatografía de lecho móvil simulado - Google Patents
Proceso de purificación de un oligosacárido de leche humana neutro mediante cromatografía de lecho móvil simulado Download PDFInfo
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- ES2868249T3 ES2868249T3 ES14777665T ES14777665T ES2868249T3 ES 2868249 T3 ES2868249 T3 ES 2868249T3 ES 14777665 T ES14777665 T ES 14777665T ES 14777665 T ES14777665 T ES 14777665T ES 2868249 T3 ES2868249 T3 ES 2868249T3
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- lacto
- human milk
- milk oligosaccharide
- neutral human
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| EP13187369.7A EP2857410A1 (en) | 2013-10-04 | 2013-10-04 | Process for purification of 2´-fucosyllactose using simulated moving bed chromatography |
| PCT/EP2014/071145 WO2015049331A1 (en) | 2013-10-04 | 2014-10-02 | Process for purification of a neutral human milk oligosaccharide using simulated moving bed chromatography |
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| ES2868249T3 true ES2868249T3 (es) | 2021-10-21 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2857410A1 (en) | 2013-10-04 | 2015-04-08 | Jennewein Biotechnologie GmbH | Process for purification of 2´-fucosyllactose using simulated moving bed chromatography |
| DK2896628T3 (en) | 2014-01-20 | 2019-01-14 | Jennewein Biotechnologie Gmbh | Process for Effective Purification of Neutral Milk Oligosaccharides (HMOs) from Microbial Fermentation |
| US10314852B2 (en) | 2014-10-24 | 2019-06-11 | Glycom A/S | Mixtures of HMOs |
| EP3390652B1 (en) | 2015-12-18 | 2024-12-04 | Glycom A/S | Fermentative production of oligosaccharides |
| US11312741B2 (en) | 2016-04-19 | 2022-04-26 | Glycom A/S | Separation of oligosaccharides from fermentation broth |
| WO2017221208A1 (en) | 2016-06-24 | 2017-12-28 | Glycom A/S | Compositions comprising hmos, their production and use for the prevention and/or treatment of viral and/or bacterial infections |
| KR101979608B1 (ko) * | 2017-04-17 | 2019-08-28 | 재단법인 탄소순환형 차세대 바이오매스 생산전환 기술연구단 | 푸코오스 분리방법 및 이를 위한 장치 |
| AU2018295414A1 (en) * | 2017-07-07 | 2020-01-16 | Societe Des Produits Nestle S.A. | Human milk fortifier |
| WO2019012461A1 (en) | 2017-07-12 | 2019-01-17 | Glycom A/S | AMORPHOUS MIXTURE COMPRISING A NEUTRAL MONO- OR OLIGOSACCHARIDE AND A NON-GLUCIDIC ACID COMPONENT |
| EP3450443A1 (en) * | 2017-08-29 | 2019-03-06 | Jennewein Biotechnologie GmbH | Process for purifying sialylated oligosaccharides |
| WO2019050321A1 (ko) * | 2017-09-07 | 2019-03-14 | (주)프로테옴텍 | 다수의 검사선을 구비한 크로마토그래피용 스트립, 이를 포함하는 진단 키트 및 다수의 경쟁적 반응 측정 단계를 포함하는 정성, 반정량, 정량 분석방법 |
| CN111164090A (zh) * | 2017-09-29 | 2020-05-15 | 菲仕兰坎皮纳荷兰公司 | 用于从微生物发酵纯化中性母乳寡糖（hmo）的方法 |
| EP3494805B1 (en) | 2017-12-08 | 2025-08-13 | Chr. Hansen HMO GmbH | Spray-dried tetrasaccharides |
| PL3494804T3 (pl) | 2017-12-08 | 2025-10-06 | Chr. Hansen HMO GmbH | Suszona rozpyłowo 3-fukozylolaktoza |
| EP3494807A1 (en) | 2017-12-11 | 2019-06-12 | Jennewein Biotechnologie GmbH | Spray-dried sialyllactose |
| ES3040419T3 (en) | 2017-12-08 | 2025-10-30 | Chr Hansen Hmo Gmbh | Spray-dried lacto-n-fucopentaose |
| CN111447845B (zh) * | 2017-12-08 | 2022-10-28 | 科汉森母乳低聚糖股份有限公司 | 喷雾干燥的唾液酸乳糖 |
| PL3524067T3 (pl) | 2018-02-08 | 2025-06-09 | Chr. Hansen HMO GmbH | Suszona rozpyłowo mieszanina oligosacharydów mleka ludzkiego |
| EP3546060A1 (en) * | 2018-03-27 | 2019-10-02 | DuPont Nutrition Biosciences ApS | Process for spray drying fucosyllactose solutions and related product compositions |
| WO2019160922A1 (en) * | 2018-02-19 | 2019-08-22 | Dupont Nutrition Biosciences Aps | Process for spray drying fucosyllactose solutions and related product compositions |
| KR20210006916A (ko) | 2018-05-07 | 2021-01-19 | 젠와인 바이오테크놀로지 게엠바하 | 미생물 발효에 의해 수득된 탄수화물로부터 락토-Ｎ-네오테트라오스 (LNnT)를 정제하기 위한 간단한 방법 |
| WO2019226431A1 (en) * | 2018-05-23 | 2019-11-28 | Dsm Ip Assets B.V. | Production of oligosaccharides |
| US20210298328A1 (en) * | 2018-08-08 | 2021-09-30 | Mars, Incoroprated | Pet food products comprising oligosaccharides and methods of use |
| AU2019362595B2 (en) | 2018-10-18 | 2024-12-19 | Basf Se | Crystalline form II of 2'-O-fucosyllactose, process for its preparation, nutritional, cosmetic or pharmaceutical formulation containing the same |
| EP3741770A1 (en) * | 2019-05-21 | 2020-11-25 | Jennewein Biotechnologie GmbH | Purification of oligosaccharides from a fermentation broth by using filtration |
| EP3750902A1 (en) * | 2019-06-14 | 2020-12-16 | Jennewein Biotechnologie GmbH | Process for the purification of lacto-n-neotetraose |
| WO2021011905A1 (en) * | 2019-07-18 | 2021-01-21 | The Regents Of The University Of California | Human milk oligosaccharides for control of dietary response and metabolic phenotype |
| MX2022002949A (es) | 2019-09-24 | 2022-04-06 | Prolacta Bioscience Inc | Composiciones y metodos para el tratamiento de enfermedades inflamatorias e inmunes. |
| CN110672756B (zh) * | 2019-11-07 | 2020-12-29 | 江南大学 | 一种奶粉中2’-岩藻糖基乳糖含量的检测方法 |
| CN115003681B (zh) * | 2020-01-29 | 2024-07-05 | 帝斯曼知识产权资产管理有限公司 | 用于回收和纯化人乳寡糖的方法 |
| KR20220155595A (ko) * | 2020-03-20 | 2022-11-23 | 글리콤 에이/에스 | 고체 hmo 생성물을 제공하는 방법, 및 이에 의해 수득된 고체 hmo 생성물 |
| WO2021250191A1 (en) * | 2020-06-12 | 2021-12-16 | Basf Se | Improved demineralization of fermentation broths and purification of fine chemicals such as oligosaccharides |
| IL300573A (en) | 2020-08-14 | 2023-04-01 | Prolacta Bioscience Inc | Breast milk oligosaccharide compositions for use with bacteriotherapy |
| CN112526022A (zh) * | 2020-11-27 | 2021-03-19 | 内蒙古伊利实业集团股份有限公司 | 一种乳中母乳低聚糖的检测方法 |
| JP2024502629A (ja) | 2021-01-12 | 2024-01-22 | プロラクタ バイオサイエンス，インコーポレイテッド | シンバイオティック治療レジメン |
| EP4418878A1 (en) * | 2021-10-18 | 2024-08-28 | DSM IP Assets B.V. | A method for providing an amorphous hmo product by drying |
| CN117003803A (zh) | 2022-05-07 | 2023-11-07 | 山东恒鲁生物科技有限公司 | 一种三糖的新晶型 |
| CN115873051B (zh) | 2022-05-17 | 2024-06-25 | 山东恒鲁生物科技有限公司 | 三糖的新晶型 |
| CN115073539B (zh) * | 2022-07-21 | 2023-06-16 | 南京工业大学 | 一种2’-岩藻糖基乳糖分离纯化的方法 |
| CN115260255B (zh) * | 2022-08-30 | 2024-06-28 | 南京工业大学 | 一种利用模拟移动床分离纯化2’-岩藻糖基乳糖的方法 |
| WO2024130119A2 (en) | 2022-12-16 | 2024-06-20 | Prolacta Bioscience, Inc. | Synbiotic compositions for short chain fatty acid production |
| CN115856151B (zh) * | 2022-12-27 | 2025-08-12 | 深圳市中科朗健生物技术有限公司 | 一种同时测定多种人乳低聚糖的高效液相色谱检测方法 |
| CN115838390A (zh) * | 2022-12-30 | 2023-03-24 | 保龄宝生物股份有限公司 | 一种利用三组分色谱分离技术制备高含量2′-岩藻糖基乳糖的方法 |
| WO2024165630A1 (en) * | 2023-02-07 | 2024-08-15 | N.V. Nutricia | Nutritional composition with improved segregation resistance |
| CN118805902A (zh) * | 2023-04-19 | 2024-10-22 | 科·汉森有限公司 | 母乳低聚糖 |
| WO2025056571A1 (en) | 2023-09-12 | 2025-03-20 | Frieslandcampina Nederland B.V. | Milk extracellular vesicle enrichment process |
| CN117089503B (zh) | 2023-10-17 | 2024-01-02 | 保龄宝生物股份有限公司 | 一种大肠杆菌k-12 mg1655 blbyzt6及其应用 |
| WO2025149372A1 (en) | 2024-01-09 | 2025-07-17 | Frieslandcampina Nederland B.V. | Milk extracellular vesicle enrichment process using peg |
| CN119192253B (zh) * | 2024-09-06 | 2025-10-21 | 虹摹生物科技(上海)有限公司 | 一种岩藻糖基乳糖及其纯化方法 |
| CN120847064B (zh) * | 2025-09-23 | 2025-12-05 | 吉林省科技创新研究院有限公司 | 一种液体中微量可见异物分析鉴定方法 |
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| JP5184768B2 (ja) | 2006-09-05 | 2013-04-17 | 株式会社林原 | トレハロース高含有糖液の回収方法並びに結晶トレハロースの製造方法 |
| EP2293677B1 (en) | 2008-06-13 | 2017-11-15 | N.V. Nutricia | Nutritional composition for infants delivered via caesarean section |
| CN101367844A (zh) * | 2008-09-17 | 2009-02-18 | 无锡绿色分离应用技术研究所有限公司 | 一种从阿拉伯胶水解液中提取阿拉伯糖的方法 |
| CN102459295A (zh) | 2009-04-07 | 2012-05-16 | 格礼卡姆股份公司 | 2’-o-岩藻糖基乳糖的合成 |
| ES2660698T3 (es) * | 2009-06-08 | 2018-03-23 | Jennewein Biotechnologie Gmbh | Síntesis de HMO |
| CN101831475A (zh) * | 2010-03-24 | 2010-09-15 | 方煜宇 | 一种生产高纯度低聚半乳糖的方法 |
| CN103025749B (zh) * | 2010-06-01 | 2016-06-01 | 格礼卡姆股份公司 | 2’-o-岩藻糖基乳糖的多晶型物及其制备 |
| EP2465507A1 (en) | 2010-11-23 | 2012-06-20 | Nestec S.A. | Oligosaccharide composition for treating skin diseases |
| DE12746649T1 (de) | 2011-02-16 | 2016-09-29 | Glycosyn LLC | Biosynthese menschlicher milcholigosaccaride in manipulierten Bakterien |
| CN102676604A (zh) * | 2011-03-08 | 2012-09-19 | 保龄宝生物股份有限公司 | 一种连续模拟移动床色谱分离制备高纯度低聚半乳糖的方法 |
| AU2012257395A1 (en) * | 2011-05-13 | 2013-12-12 | Glycom A/S | Method for generating human milk oligosaccharides (HMOs) or precursors thereof |
| US9382564B2 (en) * | 2011-05-13 | 2016-07-05 | Glycom A/S | Diversification of human milk oligosaccharides (HMOs) or precursors thereof |
| JP6129821B2 (ja) * | 2011-05-13 | 2017-05-17 | グリコシン リミテッド ライアビリティー カンパニー | プレバイオティクスとしての、精製された２’−フコシルラクトース、３−フコシルラクトース、およびラクトジフコテトラオースの使用 |
| EP2526784A1 (en) * | 2011-05-24 | 2012-11-28 | Nestec S.A. | Milk oligosaccharide-galactooligosaccharide composition for infant formula containing the soluble oligosaccharide fraction present in milk, and having a low level of monosaccharides, and a process to produce the composition |
| DE202013012827U1 (de) * | 2012-06-14 | 2020-02-13 | Glycom A/S | Verbesserung der Stabilität und Reinheit sowie Erhöhung der Bioverfügbarkeit von menschlichen Milch-Oligosacchariden oder Vorläufern oder Mischungen davon |
| CN103113422B (zh) * | 2013-02-06 | 2015-06-10 | 广西轻工业科学技术研究院 | 一种用模拟流动床分离精制高纯度l-阿拉伯糖、d-木糖的方法 |
| EP2857410A1 (en) | 2013-10-04 | 2015-04-08 | Jennewein Biotechnologie GmbH | Process for purification of 2´-fucosyllactose using simulated moving bed chromatography |
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| BR112016007342A2 (pt) | 2017-08-01 |
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| CN109705175B (zh) | 2022-07-05 |
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| PL3063159T3 (pl) | 2021-07-19 |
| PH12016500594A1 (en) | 2016-06-13 |
| EP3063159B1 (en) | 2021-04-07 |
| RU2016109548A (ru) | 2017-11-09 |
| US20160237104A1 (en) | 2016-08-18 |
| EP3063159A1 (en) | 2016-09-07 |
| KR102298281B1 (ko) | 2021-09-07 |
| PH12016500594B1 (en) | 2023-10-20 |
| RU2016109548A3 (enExample) | 2018-06-25 |
| WO2015049331A1 (en) | 2015-04-09 |
| BR112016007342B1 (pt) | 2020-11-17 |
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