ES2860423T3 - Métodos y sistemas para convertir células precursoras en tejidos gástricos mediante diferenciación dirigida - Google Patents

Métodos y sistemas para convertir células precursoras en tejidos gástricos mediante diferenciación dirigida Download PDF

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ES2860423T3
ES2860423T3 ES15728704T ES15728704T ES2860423T3 ES 2860423 T3 ES2860423 T3 ES 2860423T3 ES 15728704 T ES15728704 T ES 15728704T ES 15728704 T ES15728704 T ES 15728704T ES 2860423 T3 ES2860423 T3 ES 2860423T3
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gastric
cell
activator
signaling pathway
cells
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James Wells
Kyle Mccracken
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Cincinnati Childrens Hospital Medical Center
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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  • Health & Medical Sciences (AREA)
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  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES15728704T 2014-05-28 2015-05-27 Métodos y sistemas para convertir células precursoras en tejidos gástricos mediante diferenciación dirigida Active ES2860423T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462003719P 2014-05-28 2014-05-28
PCT/US2015/032626 WO2015183920A2 (en) 2014-05-28 2015-05-27 Methods and systems for converting precursor cells into gastric tissues through directed differentiation

Publications (1)

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ES2860423T3 true ES2860423T3 (es) 2021-10-05

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US (3) US10174289B2 (enExample)
EP (2) EP3149156B1 (enExample)
JP (4) JP6687544B2 (enExample)
CN (2) CN113249297B (enExample)
AU (2) AU2015267148B2 (enExample)
CA (1) CA2949834A1 (enExample)
ES (1) ES2860423T3 (enExample)
IL (1) IL249253B (enExample)
SG (2) SG10201801654RA (enExample)
WO (1) WO2015183920A2 (enExample)

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