MA40495A - Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production - Google Patents

Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production

Info

Publication number
MA40495A
MA40495A MA040495A MA40495A MA40495A MA 40495 A MA40495 A MA 40495A MA 040495 A MA040495 A MA 040495A MA 40495 A MA40495 A MA 40495A MA 40495 A MA40495 A MA 40495A
Authority
MA
Morocco
Prior art keywords
arrays
making
methods
same
renal
Prior art date
Application number
MA040495A
Other languages
English (en)
Inventor
Shelby Marie King
Deborah Lynn Greene Nguyen
Sharon C Presnell
Original Assignee
Organovo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organovo Inc filed Critical Organovo Inc
Publication of MA40495A publication Critical patent/MA40495A/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/25—Urinary tract cells, renal cells
    • C12N2502/256—Renal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Abstract

L'invention concerne des tissus rénaux et des réseaux de ces derniers qui comprennent une couche de tissus interstitiels rénaux, les tissus interstitiels rénaux comprenant des fibroblastes rénaux et des cellules endothéliales, et une couche de tissu épithéliaux rénaux, les tissus épithéliaux rénaux comprenant des cellules épithéliales tubulaires rénales et les les tissus épithéliaux rénaux étant en contact avec la couche de tissus interstitiels rénaux afin de former des tissus rénaux biologiques obtenus p
MA040495A 2014-10-06 2015-10-06 Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production MA40495A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462060416P 2014-10-06 2014-10-06
US201562140285P 2015-03-30 2015-03-30

Publications (1)

Publication Number Publication Date
MA40495A true MA40495A (fr) 2016-04-14

Family

ID=55632374

Family Applications (1)

Application Number Title Priority Date Filing Date
MA040495A MA40495A (fr) 2014-10-06 2015-10-06 Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production

Country Status (11)

Country Link
US (4) US9481868B2 (fr)
EP (1) EP3204488B1 (fr)
JP (2) JP2017529877A (fr)
KR (1) KR20170064547A (fr)
CN (1) CN107002033B (fr)
AU (1) AU2015328173B2 (fr)
CA (1) CA2962778C (fr)
MA (1) MA40495A (fr)
RU (1) RU2017110275A (fr)
SG (1) SG11201702795QA (fr)
WO (1) WO2016057571A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011140441A2 (fr) 2010-05-06 2011-11-10 Children's Hospital Medical Center Procédés et systèmes de conversion de cellules précurseurs en tissus intestinaux par différenciation dirigée
CA3157246A1 (en) * 2011-09-12 2013-03-21 Organovo, Inc. Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same
AU2015267148B2 (en) 2014-05-28 2021-07-29 Children's Hospital Medical Center Methods and systems for converting precursor cells into gastric tissues through directed differentiation
MA40495A (fr) 2014-10-06 2016-04-14 Organovo Inc Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production
EP3207123A1 (fr) 2014-10-17 2017-08-23 Children's Hospital Center D/b/a Cincinnati Children's Hospital Medical Center Modèle in vivo d'intestin grêle humain faisant intervenir des cellules souches pluripotentes et ses procédés de fabrication et d'utilisation
WO2017123722A1 (fr) 2016-01-12 2017-07-20 Cleveland State University Constructions biologiques miniatures imprimées en 3d
WO2017183673A1 (fr) * 2016-04-19 2017-10-26 凸版印刷株式会社 Procédé d'évaluation de médicament anticancéreux
WO2017192997A1 (fr) 2016-05-05 2017-11-09 Children's Hospital Medical Center Procédés de fabrication in vitro de tissu de fundus d'estomac et compositions associées à celui-ci
WO2018064323A1 (fr) 2016-09-28 2018-04-05 Organovo, Inc. Utilisation de tissus rénaux modifiés dans des tests
KR20190076023A (ko) * 2016-11-10 2019-07-01 오가노보, 인크. 조작된 장 조직(engineered intestinal tissue) 및 그의 용도
CA3043708A1 (fr) 2016-11-17 2018-05-24 Cleveland State University Plates-formes de puce pour la bio-impression 3d de microreseau
NZ753873A (en) 2016-12-05 2023-01-27 Children’S Hospital Medical Center Colonic organoids and methods of making and using same
EP3674706A4 (fr) * 2017-08-21 2020-08-12 Toppan Printing Co., Ltd. Procédé d'évaluation d'un effet anticancéreux et procédé de prédiction de l'efficacité d'une immunothérapie anticancéreuse
US11262349B2 (en) 2017-10-11 2022-03-01 Cleveland State University Multiplexed immune cell assays on a micropillar/microwell chip platform
EP3697340A4 (fr) 2017-10-20 2021-08-04 Indiana University Research & Technology Corporation Bio-impression 3d de cellules porcines sans échafaudage
CN108130313B (zh) * 2017-12-28 2021-04-30 杭州枫霖科技有限公司 一种基于生物3d打印构建三维胶质瘤组织的方法
DE102018111751A1 (de) * 2018-05-16 2019-11-21 Cellbricks Gmbh Verfahren zur Herstellung eines Zellkultureinsatzes mit mindestens einer Membran
JP2022521010A (ja) * 2019-02-21 2022-04-04 イッスム・リサーチ・デベロプメント・カムパニー・オブ・ザ・ヘブリュー・ユニバシティー・オブ・エルサレム リミテッド 薬物誘導性腎毒性を減少させるための方法
KR102438496B1 (ko) 2020-09-07 2022-09-02 포항공과대학교 산학협력단 생체외 인공장기 모델 및 세포 치료제로의 적용이 가능한 관류형 이중 근위세뇨관 관상 세포 구조체 및 그 생성 방법

Family Cites Families (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4759764A (en) 1985-05-24 1988-07-26 Clayton Foundation For Research Peripheral nerve regeneration
US4808435A (en) 1987-04-06 1989-02-28 International Business Machines Corporation Screen printing method for producing lines of uniform width and height
US5099090A (en) 1988-05-11 1992-03-24 Ariel Electronics, Inc. Circuit writer
DE69727817T2 (de) * 1996-09-05 2005-01-05 Children's Medical Center Corp., Boston Nierenprothese und ihre Verwendung zum Behandeln einer Nierenkrankheit
WO1999001538A1 (fr) 1997-07-03 1999-01-14 Massachusetts Institute Of Technology Tissus obtenus par synthese
US6401795B1 (en) 1997-10-28 2002-06-11 Sandia Corporation Method for freeforming objects with low-binder slurry
CA2326322C (fr) 1998-04-21 2011-03-01 University Of Connecticut Nanofabrication a structure libre utilisant une excitation multiphotonique
US6697694B2 (en) 1998-08-26 2004-02-24 Electronic Materials, L.L.C. Apparatus and method for creating flexible circuits
US7338798B2 (en) 1998-09-15 2008-03-04 The Regents Of The University Of Michigan System and method for forming a cardiac muscle construct
EP1029692B9 (fr) 1999-02-17 2003-12-03 Hewlett-Packard Company, A Delaware Corporation Appareil d'impression
US6979670B1 (en) 1999-03-10 2005-12-27 Biora Bioex Ab Matrix protein compositions for grafting
US6642243B1 (en) 1999-07-22 2003-11-04 Ashkan Imanzahrai Migraine medicine and method for treating same
JP2001145956A (ja) 1999-11-19 2001-05-29 Meiko:Kk 光硬化性樹脂三次元造形物の積層造形装置及びその積層造形方法
US6503273B1 (en) 1999-11-22 2003-01-07 Cyograft Tissue Engineering, Inc. Tissue engineered blood vessels and methods and apparatus for their manufacture
US6454972B1 (en) 1999-11-24 2002-09-24 Sandia Corporation Solid freeform fabrication using chemically reactive suspensions
US6520997B1 (en) 1999-12-08 2003-02-18 Baxter International Inc. Porous three dimensional structure
US6315469B1 (en) 2000-01-19 2001-11-13 Hewlett-Packard Company Tool and method for adjustment of printhead to platen spacing in a printer
DE10013223C2 (de) 2000-03-13 2002-07-18 Co Don Ag Verfahren zur in vitro-Herstellung von dreidimensionalem, vitalem Knorpel- oder Knochengewebe und dessen Verwendung als Transplantationsmaterial
US20050091576A1 (en) 2003-10-24 2005-04-28 Microsoft Corporation Programming interface for a computer platform
DE10018987A1 (de) 2000-04-17 2001-10-31 Envision Technologies Gmbh Vorrichtung und Verfahren zum Herstellen von dreidimensionalen Objekten
WO2002004113A2 (fr) 2000-07-11 2002-01-17 The Johns Hopkins University School Of Medicine Procede pour creer un motif d'adhesivite proteique et cellulaire
US7998735B2 (en) 2000-08-21 2011-08-16 Victorian Tissue Engineering Centre Pty. Ltd. Vascularized tissue graft
US6561607B1 (en) 2000-10-05 2003-05-13 Eastman Kodak Company Apparatus and method for maintaining a substantially constant closely spaced working distance between an inkjet printhead and a printing receiver
US6939489B2 (en) 2001-03-23 2005-09-06 Ivoclar Vivadent Ag Desktop process for producing dental products by means of 3-dimensional plotting
US6849223B2 (en) 2001-04-19 2005-02-01 Case Western Reserve University Fabrication of a polymeric prosthetic implant
DE10127225A1 (de) 2001-05-22 2002-11-28 Zeiss Carl Ultraviolettlicht-Abschwächungsfilter
US20030049839A1 (en) 2001-08-01 2003-03-13 The University Of Texas System Transparent multi-channel cell scaffold that creates a cellular and/or molecular gradient
US6986739B2 (en) 2001-08-23 2006-01-17 Sciperio, Inc. Architecture tool and methods of use
JP4023597B2 (ja) 2001-09-25 2007-12-19 独立行政法人科学技術振興機構 基底膜標品等を用いた再構築人工組織及びその製造方法
US6934600B2 (en) 2002-03-14 2005-08-23 Auburn University Nanotube fiber reinforced composite materials and method of producing fiber reinforced composites
AU2003224710A1 (en) 2002-03-18 2003-10-08 Carnegie Mellon University Method and apparatus for preparing biomimetic scaffold
US20100254900A1 (en) 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
US6907307B2 (en) 2002-07-02 2005-06-14 3D Systems, Inc. Support volume calculation for a CAD model
AU2003251874A1 (en) 2002-07-12 2004-02-02 Dirk R. Albrecht Three dimensional cell patterned bioploymer scaffolds and method of making the same
US7641898B2 (en) 2003-03-21 2010-01-05 Materials Evolution And Development Usa, Inc. Keratinocyte-fibrocyte concomitant grafting for wound healing
US20040197375A1 (en) 2003-04-02 2004-10-07 Alireza Rezania Composite scaffolds seeded with mammalian cells
WO2004091495A2 (fr) * 2003-04-09 2004-10-28 University Of Utah Research Foundation Compositions et procedes associes a la production d'erythropoietine
US7051654B2 (en) 2003-05-30 2006-05-30 Clemson University Ink-jet printing of viable cells
US7338517B2 (en) 2003-06-04 2008-03-04 University Of South Carolina Tissue scaffold having aligned fibrils and artificial tissue comprising the same
JP4474858B2 (ja) 2003-07-07 2010-06-09 セイコーエプソン株式会社 ギャップ調整装置、これに使用されるキャリブレーション用治具、およびギャップ調整装置を備えた液滴吐出装置、並びに電気光学装置の製造方法
US20050074877A1 (en) 2003-07-28 2005-04-07 Mao Jeremy Jian Biological engineering of articular structures containing both cartilage and bone
FR2859128B1 (fr) 2003-08-29 2006-03-10 Centre Nat Rech Scient Procede et dispositif de fabrication d'un composant multimateriaux tridimensionnel par impression du type jet d'encre
US8043614B2 (en) 2004-03-09 2011-10-25 Ahlfors Jan-Eric W Autogenic living scaffolds and living tissue matrices: methods and uses thereof
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
US20050276791A1 (en) 2004-02-20 2005-12-15 The Ohio State University Multi-layer polymer scaffolds
US8241905B2 (en) 2004-02-24 2012-08-14 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
US20090142307A1 (en) 2004-07-09 2009-06-04 Athanasiou Kyriacos A Shape-Based Approach for Scaffoldless Tissue Engineering
US7625198B2 (en) 2004-08-11 2009-12-01 Cornell Research Foundation, Inc. Modular fabrication systems and methods
US7651665B2 (en) 2004-09-07 2010-01-26 Hewlett-Packard Development Company, L.P. Microtray for handling biosubstances
US7767446B2 (en) 2004-09-16 2010-08-03 Becton, Dickinson And Company Perfusion bioreactors for culturing cells
KR100606457B1 (ko) 2004-11-11 2006-11-23 한국기계연구원 3차원 프린팅 조형시스템
JP4539316B2 (ja) 2004-12-08 2010-09-08 セイコーエプソン株式会社 ヘッド位置補正方法およびヘッド位置補正装置、並びに液滴吐出装置、電気光学装置の製造方法
US7568904B2 (en) 2005-03-03 2009-08-04 Laser Solutions Co., Ltd. Stereolithography apparatus
JP4729948B2 (ja) 2005-03-09 2011-07-20 ブラザー工業株式会社 液体供給装置、この液体供給装置を備えたインクジェット記録装置
US7780897B2 (en) 2005-04-22 2010-08-24 Board Of Regents, The University Of Texas System Hydrogel constructs using stereolithography
EP2495310A3 (fr) 2005-05-24 2013-03-27 The Regents Of the University of California Microfiltration à micromotifs créée dans des tissus in vitro
WO2007126411A2 (fr) 2005-07-28 2007-11-08 Carnegie Mellon University Polymères biocompatibles et procédés d'utilisation
US8690957B2 (en) 2005-12-21 2014-04-08 Warsaw Orthopedic, Inc. Bone graft composition, method and implant
US20070200276A1 (en) 2006-02-24 2007-08-30 Micron Technology, Inc. Method for rapid printing of near-field and imprint lithographic features
US7680555B2 (en) 2006-04-03 2010-03-16 Stratasys, Inc. Auto tip calibration in an extrusion apparatus
US20070231787A1 (en) 2006-04-04 2007-10-04 Voelker Mark A Methods and devices for imaging and manipulating biological samples
CA2648648A1 (fr) 2006-04-05 2007-11-29 William Marsh Rice University Cellules derivees du derme pour des applications de genie histologique
US20090208466A1 (en) 2006-04-21 2009-08-20 James Yoo Ink-jet printing of tissues
JP4051077B2 (ja) 2006-04-28 2008-02-20 シャープ株式会社 液滴塗布装置、液滴吐出部のギャップ測定方法、および、液滴吐出部のギャップ調整方法
FR2901143B1 (fr) 2006-05-16 2008-10-03 Centre Nat Rech Scient "methode de construction de materiaux vivants fonctionnels, materiaux obtenus et applications"
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
DE102006053121B3 (de) 2006-11-10 2007-12-27 Eos Gmbh Electro Optical Systems Vorrichtung und Verfahren zum Herstellen eines dreidimensionalen Objektes mittels eines Beschichters für pulverförmiges Aufbaumaterial
CA2675147C (fr) 2007-01-10 2012-09-11 Hemoshear, Llc Utilisation d'un modele de co-culture de cellules endotheliales/de muscles lisses hemodynamique in vitro pour identifier de nouvelles cibles therapeutiques pour les maladies vasculaires
US8097455B2 (en) 2007-02-02 2012-01-17 The Regents Of The University Of Michigan System and method for forming skeletal muscle constructs having functional tissue interfaces
US8343740B2 (en) 2007-03-29 2013-01-01 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Micro-organ device
US20090117087A1 (en) 2007-04-13 2009-05-07 Wake Forest University Methods and compositions for printing biologically compatible nanotube composites of autologous tissue
CN101796186B (zh) 2007-06-07 2013-05-22 韦克福里斯特大学健康科学院 喷墨基因打印
EP2188114B1 (fr) 2007-07-25 2018-09-12 Stratasys Ltd. Fabrication en forme irrégulière solide à l'aide d'une pluralité de matériaux de modelage
DK2195131T3 (da) 2007-08-29 2011-12-12 Vito Nv Fremgangmåde til fremstilling af en tre-dimensionel makroporøs filamentkonstruktion baseret på faseinversion og konstruktion opnået derved
US20090076531A1 (en) 2007-09-18 2009-03-19 Richardson Charles L Method and apparatus for bypass graft
US7923846B2 (en) 2007-11-16 2011-04-12 Stats Chippac Ltd. Integrated circuit package-in-package system with wire-in-film encapsulant
EP2090584A1 (fr) 2008-02-13 2009-08-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Identification d'un nouveau peptide à pénétration de cellule riche en cystéine
KR100922232B1 (ko) 2008-02-13 2009-10-16 연세대학교 산학협력단 전기수력학 프린팅 기법을 이용한 살아있는 세포의 직접패터닝 방법 및 장치
US8691274B2 (en) 2008-02-14 2014-04-08 Wake Forest University Health Sciences Inkjet printing of tissues and cells
US20090248145A1 (en) 2008-03-28 2009-10-01 Nanyang Technological University Method of forming a three-dimensional structure of unidirectionally aligned cells
US8876513B2 (en) 2008-04-25 2014-11-04 3D Systems, Inc. Selective deposition modeling using CW UV LED curing
US9303245B2 (en) 2008-06-20 2016-04-05 Universiteit Maastricht Self-assembling tissue modules
CA2949615A1 (fr) 2008-06-24 2010-01-21 The Curators Of The University Of Missouri Corps multicellulaires auto-assembles et procedes de production d'une structure biologique tridimensionnelle utilisant ceux-ci
US9097702B2 (en) 2008-07-29 2015-08-04 Cornell University Pathologically relevant tumor microenvironments for high-throughput drug screening
WO2010030964A2 (fr) 2008-09-12 2010-03-18 The Brigham And Women's Hospital, Inc. Hydrogels multicouches tridimensionnels et leurs procédés de préparation
US20110250688A1 (en) 2008-11-24 2011-10-13 Immunotrex Corporation Three Dimensional Tissue Generation
EP2450707B1 (fr) 2010-11-04 2016-04-27 University of Pécs Modèle de tissu de poumon
WO2011038373A2 (fr) 2009-09-28 2011-03-31 Virginia Tech Intellectual Properties, Inc. Bioimpressions tridimensionnelles d'implants de cellulose biosynthétique et d'échafaudages pour ingénierie tissulaire
US8409603B2 (en) 2009-10-01 2013-04-02 University Of South Carolina Compositions and methods for tissue engineering, tissue regeneration and wound healing
EP2521587B1 (fr) 2010-01-08 2020-04-08 Wake Forest University Health Sciences Système d'administration
WO2011088213A1 (fr) 2010-01-15 2011-07-21 University Of Utah Research Foundation Hydrogels réticulés et leurs procédés de fabrication et d'utilisation
CN102869391A (zh) 2010-02-02 2013-01-09 密苏里大学管理者 工程化生物神经移植物的制备及其应用
ES2671594T3 (es) 2010-03-04 2018-06-07 INSERM (Institut National de la Santé et de la Recherche Médicale) Puesto de bioimpresión, ensamblaje que comprende dicho puesto de bioimpresión y método de bioimpresión
GB2478801B (en) 2010-03-16 2012-05-30 Organovo Inc Multilayered vascular tubes
US9012415B2 (en) 2010-03-26 2015-04-21 Stemmatters, Biotecnologia E Medicina Regenerativa S.A. Photo-crosslinked gellan gum-based hydrogels: preparation methods and uses thereof
US9592255B2 (en) 2010-07-01 2017-03-14 The Regents Of The University Of Michigan Scaffold-free three dimensional nerve fibroblast constructs
US20120089238A1 (en) 2010-10-06 2012-04-12 Hyun-Wook Kang Integrated organ and tissue printing methods, system and apparatus
BR112013009744A2 (pt) 2010-10-21 2016-07-19 Organovo Inc dispositivo, sistemas e métodos para a fabricação de tecido
DE202011003443U1 (de) 2011-03-02 2011-12-23 Bego Medical Gmbh Vorrichtung zur generativen Herstellung dreidimensionaler Bauteile
AU2012225644B2 (en) 2011-03-07 2017-05-04 Wake Forest University Health Sciences Delivery system
GB201105226D0 (en) 2011-03-29 2011-05-11 Univ Leiden Methods
JP5599356B2 (ja) 2011-03-31 2014-10-01 富士フイルム株式会社 シミュレーション方法、プログラムおよびそれを記録した記録媒体、並びに、それらを利用した液滴配置パターンの作成方法、ナノインプリント方法、パターン化基板の製造方法およびインクジェット装置。
CA3157246A1 (en) * 2011-09-12 2013-03-21 Organovo, Inc. Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same
WO2013040087A2 (fr) 2011-09-12 2013-03-21 Organovo, Inc. Plateforme pour des tissus et organes artificiels implantables et procédés de fabrication de ces tissus et organes
EP3425391A1 (fr) 2011-11-04 2019-01-09 inRegen Tests de puissance et de criblage de médicaments
WO2013116443A1 (fr) 2012-02-01 2013-08-08 Nscrypt, Inc. Micro-distribution d'objets 3d multicouches avec étapes de durcissement
US10072257B2 (en) 2012-02-29 2018-09-11 Massachusetts Institute Of Technology Inverse patterning process for three-dimensional multi-compartmental micro-organization of multiple cell types
CA2866267A1 (fr) 2012-03-06 2013-09-12 The Uab Research Foundation Constructions de tissu tridimensionnelles, prevascularisees, fabriquees, procedes de fabrication et procedes d'utilisation des constructions de tissu
US9499779B2 (en) 2012-04-20 2016-11-22 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
US20140099709A1 (en) 2012-06-19 2014-04-10 Organovo, Inc. Engineered three-dimensional connective tissue constructs and methods of making the same
US9421716B2 (en) 2012-08-08 2016-08-23 Makerbot Industries, Llc Photo booth for three-dimensional images
US9442105B2 (en) 2013-03-15 2016-09-13 Organovo, Inc. Engineered liver tissues, arrays thereof, and methods of making the same
WO2014144482A1 (fr) 2013-03-15 2014-09-18 Matterfab Corp. Appareil et procédés de fabrication
US9802360B2 (en) 2013-06-04 2017-10-31 Stratsys, Inc. Platen planarizing process for additive manufacturing system
WO2015017579A1 (fr) 2013-07-31 2015-02-05 Organovo, Inc. Dispositifs, systèmes et procédés automatisés pour la fabrication de tissus
EP3065875A4 (fr) 2013-11-04 2018-02-07 University of Iowa Research Foundation Bio-imprimante et procédés pour l'utiliser
MA40495A (fr) 2014-10-06 2016-04-14 Organovo Inc Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production

Also Published As

Publication number Publication date
CA2962778C (fr) 2023-05-16
CN107002033A (zh) 2017-08-01
AU2015328173A1 (en) 2017-04-13
US10962526B2 (en) 2021-03-30
US20170131264A1 (en) 2017-05-11
EP3204488A1 (fr) 2017-08-16
US20160097039A1 (en) 2016-04-07
AU2015328173B2 (en) 2022-01-27
CA2962778A1 (fr) 2016-04-14
SG11201702795QA (en) 2017-05-30
JP7021177B2 (ja) 2022-02-16
WO2016057571A1 (fr) 2016-04-14
US20210208132A1 (en) 2021-07-08
US9481868B2 (en) 2016-11-01
EP3204488A4 (fr) 2018-03-21
KR20170064547A (ko) 2017-06-09
US10094821B2 (en) 2018-10-09
EP3204488B1 (fr) 2019-07-17
JP2020054377A (ja) 2020-04-09
CN107002033B (zh) 2021-08-10
JP2017529877A (ja) 2017-10-12
RU2017110275A (ru) 2018-11-15
US20190041381A1 (en) 2019-02-07
US11867689B2 (en) 2024-01-09

Similar Documents

Publication Publication Date Title
MA40495A (fr) Tissus rénaux produits par génie génétique, réseaux correspondants, et procédés de production
HK1223741A1 (zh) 用於生物相容性電池的生物相容性陰極漿的製造方法
EP3215603A4 (fr) Tissus cutanés tridimensionnels manipulés, ensembles correspondants et leurs procédés de production
EP3091911A4 (fr) Guides de résection, implants et procédés
EP3229586A4 (fr) Cellules, tissus et organes génétiquement modifiés pour le traitement d'une maladie
EP3177231A4 (fr) Implant intraoculaire à micromotifs
WO2013106556A3 (fr) Prothèses mammaires, procédés de fabrication de prothèses mammaires, et procédés de traitement utilisant les prothèses mammaires
EP3126490A4 (fr) Tissu mammaire tridimensionnel artificiel, tissu adipeux, et modèle de maladies tumorales
MX2019008212A (es) Estructuras fibrosas que comprenden particulas y metodos para fabricarlas.
EP3121314A4 (fr) Fibre frisée et non-tissé
IL287921A (en) Methods for preparing an extremely dense cell pool
IL273013A (en) A cell pool that includes retinal tissue and a method for its production
EP3188739A4 (fr) Système de bioréacteur, multifonctionnel et automatisé, de culture et d'essai de tissu cardiaque obtenu par génie génétique
EP3171897A4 (fr) Implant composite biopolymère-nanoparticules pour le pistage des cellules tumorales
HK1245126A1 (zh) 包括工程化內皮細胞的生物相容性植入物
EP3120579A4 (fr) Installation-repèrage-suivi automatique fondé sur des impédances d'électrode dans des implants cochléaire
EP3547968A4 (fr) Prothèse obtenu par génie tissulaire
EP3472305A4 (fr) Cellules treg génétiquement modifiées
PT3174563T (pt) Enxerto de tecido
EP3227429A4 (fr) Récipient pour culture cellulaire et tissulaire
EP3231863A4 (fr) Procédé de production d'une sphère de cellules thérapeutiques endothéliales cornéennes de substitution
EP3226807A4 (fr) Implants mammaires
EP3168297A4 (fr) Matériau de culture de cellules cardiaques
EP3641840A4 (fr) Échafaudages pour culture cellulaire et régénération de tissus
GB201614218D0 (en) Tissue having reduced hydrogen bonding