ES2586765T3 - Control temporal in vivo de enzimas activables que degradan matriz - Google Patents
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- ES2586765T3 ES2586765T3 ES09716286.1T ES09716286T ES2586765T3 ES 2586765 T3 ES2586765 T3 ES 2586765T3 ES 09716286 T ES09716286 T ES 09716286T ES 2586765 T3 ES2586765 T3 ES 2586765T3
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
- C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/22—Cysteine endopeptidases (3.4.22)
- C12Y304/22015—Cathepsin L (3.4.22.15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24007—Interstitial collagenase (3.4.24.7), i.e. matrix metalloprotease 1 or MMP1
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Immunology (AREA)
- Biomedical Technology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Marine Sciences & Fisheries (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US6866708P | 2008-03-06 | 2008-03-06 | |
| US68667P | 2008-03-06 | ||
| US12772508P | 2008-05-14 | 2008-05-14 | |
| US127725P | 2008-05-14 | ||
| PCT/US2009/001486 WO2009111083A2 (en) | 2008-03-06 | 2009-03-06 | In vivo temporal control of activ at able matrix- degrading enzymes |
Publications (1)
| Publication Number | Publication Date |
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| ES2586765T3 true ES2586765T3 (es) | 2016-10-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| ES09716286.1T Active ES2586765T3 (es) | 2008-03-06 | 2009-03-06 | Control temporal in vivo de enzimas activables que degradan matriz |
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| CL (2) | CL2009000541A1 (https=) |
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| ES (1) | ES2586765T3 (https=) |
| IL (1) | IL207293A (https=) |
| MX (1) | MX2010009806A (https=) |
| TW (1) | TWI395593B (https=) |
| WO (1) | WO2009111083A2 (https=) |
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-
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- 2009-03-05 TW TW098107084A patent/TWI395593B/zh not_active IP Right Cessation
- 2009-03-06 AU AU2009220094A patent/AU2009220094B2/en not_active Ceased
- 2009-03-06 MX MX2010009806A patent/MX2010009806A/es active IP Right Grant
- 2009-03-06 KR KR1020107022203A patent/KR20100135779A/ko not_active Abandoned
- 2009-03-06 CL CL2009000541A patent/CL2009000541A1/es unknown
- 2009-03-06 ES ES09716286.1T patent/ES2586765T3/es active Active
- 2009-03-06 KR KR1020157004822A patent/KR101647933B1/ko not_active Expired - Fee Related
- 2009-03-06 CA CA2718549A patent/CA2718549C/en not_active Expired - Fee Related
- 2009-03-06 KR KR1020137024682A patent/KR20130106893A/ko not_active Ceased
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- 2009-03-06 BR BRPI0909622A patent/BRPI0909622A2/pt not_active IP Right Cessation
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- 2009-03-06 AR ARP090100823A patent/AR076627A1/es unknown
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- 2010-09-08 CO CO10111097A patent/CO6331294A2/es not_active Application Discontinuation
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2014
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| Publication number | Publication date |
|---|---|
| TWI395593B (zh) | 2013-05-11 |
| KR20100135779A (ko) | 2010-12-27 |
| IL207293A (en) | 2016-12-29 |
| JP2014043449A (ja) | 2014-03-13 |
| EP2274004A2 (en) | 2011-01-19 |
| US20140271609A1 (en) | 2014-09-18 |
| CL2013002070A1 (es) | 2013-11-15 |
| KR101647933B1 (ko) | 2016-08-11 |
| KR20130106893A (ko) | 2013-09-30 |
| IL207293A0 (en) | 2010-12-30 |
| CA2718549A1 (en) | 2009-09-11 |
| WO2009111083A2 (en) | 2009-09-11 |
| BRPI0909622A2 (pt) | 2019-09-24 |
| CL2009000541A1 (es) | 2009-10-09 |
| WO2009111083A3 (en) | 2010-03-25 |
| AU2009220094A1 (en) | 2009-09-11 |
| JP2011517318A (ja) | 2011-06-02 |
| MX2010009806A (es) | 2010-11-30 |
| CO6331294A2 (es) | 2011-10-20 |
| KR20160073346A (ko) | 2016-06-24 |
| CA2718549C (en) | 2016-08-09 |
| EP2274004B1 (en) | 2016-06-01 |
| US9833498B2 (en) | 2017-12-05 |
| HK1150554A1 (zh) | 2012-01-06 |
| AU2009220094B2 (en) | 2013-11-07 |
| AR076627A1 (es) | 2011-06-29 |
| TW200944227A (en) | 2009-11-01 |
| JP5709531B2 (ja) | 2015-04-30 |
| US9775889B2 (en) | 2017-10-03 |
| US20100003237A1 (en) | 2010-01-07 |
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