ES2565377T3 - Composiciones para inmunización contra Staphylococcus aureus - Google Patents
Composiciones para inmunización contra Staphylococcus aureus Download PDFInfo
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- ES2565377T3 ES2565377T3 ES12175868.4T ES12175868T ES2565377T3 ES 2565377 T3 ES2565377 T3 ES 2565377T3 ES 12175868 T ES12175868 T ES 12175868T ES 2565377 T3 ES2565377 T3 ES 2565377T3
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| MX386545B (es) | 2010-05-05 | 2025-03-19 | Univ New York | Leucocidinas de staphylococcus aureus, composiciones terapéuticas y usos de las mismas. |
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| PL3243526T3 (pl) | 2010-07-06 | 2020-05-18 | Glaxosmithkline Biologicals S.A. | Dostarczanie rna w celu wyzwolenia wielu szlaków immunologicznych |
| HUE061068T2 (hu) | 2010-08-31 | 2023-05-28 | Glaxosmithkline Biologicals Sa | Pegilált liposzómák immunogént kódoló RNS szállítására |
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| CN105999275A (zh) | 2010-09-01 | 2016-10-12 | 诺华有限公司 | 免疫增强剂吸附不溶性金属离子 |
| EP2614074A1 (en) | 2010-09-09 | 2013-07-17 | The University of Chicago | Methods and compositions involving protective staphylococcal antigens |
| EP4098324A1 (en) | 2010-10-11 | 2022-12-07 | GlaxoSmithKline Biologicals S.A. | Antigen delivery platforms |
| WO2012082914A1 (en) | 2010-12-14 | 2012-06-21 | Novartis Ag | Flow cytometry analysis of materials adsorbed to metal salts |
| JP2014507142A (ja) * | 2011-02-08 | 2014-03-27 | インテグレイテッド バイオセラピューティクス，インコーポレイテッド | α溶血素オリゴペプチドを含む免疫原性組成物 |
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| WO2012136653A1 (en) | 2011-04-08 | 2012-10-11 | Novvac Aps | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| US10766932B2 (en) | 2011-05-11 | 2020-09-08 | The Children's Medical Center Corporation | Multiple antigen presenting immunogenic composition, and methods and uses thereof |
| EP2720754B1 (en) | 2011-06-19 | 2016-10-19 | New York University | Leukotoxin e/d as a new anti-inflammatory agent and microbicide |
| JP6170913B2 (ja) | 2011-06-19 | 2017-07-26 | ニューヨーク・ユニバーシティ | 黄色ブドウ球菌感染および関連状態を治療および予防する方法 |
| CA2840989A1 (en) | 2011-07-06 | 2013-01-10 | Novartis Ag | Immunogenic combination compositions and uses thereof |
| EP4115875A1 (en) | 2011-07-06 | 2023-01-11 | GlaxoSmithKline Biologicals S.A. | Liposomes having useful n:p ratio for delivery of rna molecules |
| FR2977800B1 (fr) * | 2011-07-13 | 2014-03-14 | Sanofi Pasteur | Composition vaccinale avec des nanoparticules d'hydroxyde d'aluminium |
| EP2750707B1 (en) | 2011-08-31 | 2018-10-24 | GlaxoSmithKline Biologicals SA | Pegylated liposomes for delivery of immunogen-encoding rna |
| KR20140066212A (ko) * | 2011-09-01 | 2014-05-30 | 노파르티스 아게 | 스타필로코쿠스 아우레우스 항원의 보조제 첨가된 조제물 |
| WO2013092985A1 (en) | 2011-12-23 | 2013-06-27 | Novartis Ag | Stable compositions for immunising against staphylococcus aureus |
| CN104519910B (zh) | 2012-03-07 | 2017-05-03 | 诺华股份有限公司 | 肺炎链球菌抗原的含佐剂制剂 |
| US9320748B2 (en) | 2012-03-07 | 2016-04-26 | Novartis Ag | Immunologically useful arginine salts |
| RU2014140521A (ru) | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
| BR112014026861A2 (pt) * | 2012-04-26 | 2018-05-15 | Univ Chicago | antígenos de estafilococos coagulase e métodos de seu uso |
| US9376487B2 (en) | 2012-07-10 | 2016-06-28 | Merck Sharp & Dohme Corp. | Protective vaccine based on Staphylococcus aureus SA2493 protein |
| US20150191513A1 (en) * | 2012-08-31 | 2015-07-09 | Novartis Ag | Stabilised proteins for immunising against staphylococcus aureus |
| CN104736165A (zh) * | 2012-08-31 | 2015-06-24 | 诺华股份有限公司 | 用于针对金黄色葡萄球菌的免疫的稳定化的蛋白质 |
| JP6435261B2 (ja) | 2012-08-31 | 2018-12-05 | ノバルティス アーゲー | Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓに対する免疫化のための安定化されたタンパク質 |
| CN104582723A (zh) * | 2012-08-31 | 2015-04-29 | 诺华股份有限公司 | 用于针对金黄色葡萄球菌的免疫的稳定化的蛋白质 |
| CA2882382A1 (en) | 2012-09-18 | 2014-03-27 | Novartis Ag | Outer membrane vesicles |
| CN102993308B (zh) * | 2012-09-29 | 2014-11-05 | 重庆原伦生物科技有限公司 | 耐甲氧西林金黄色葡萄球菌（mrsa）疫苗重组蛋白抗原hi2及制备方法和应用 |
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| WO2014136086A1 (en) | 2013-03-08 | 2014-09-12 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
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| EP3077820B1 (en) * | 2013-12-03 | 2025-02-26 | Evaxion Biotech A/S | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
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| EP3083556B1 (en) | 2013-12-19 | 2019-12-25 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
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| BE1022359B1 (fr) * | 2014-03-17 | 2016-03-25 | Glaxosmithkline Biologicals Sa | Immunisation contre des infections staphylococciques des os et des articulations |
| CN112521464A (zh) * | 2014-03-26 | 2021-03-19 | 葛兰素史密丝克莱恩生物有限公司 | 突变型葡萄球菌抗原 |
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| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
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| CA3061709A1 (en) * | 2017-03-28 | 2018-10-04 | The Children's Medical Center Corporation | A multiple antigen presenting system (maps)-based staphylococcus aureus vaccine, immunogenic composition, and uses thereof |
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| GB201721576D0 (en) | 2017-12-21 | 2018-02-07 | Glaxosmithkline Biologicals Sa | Hla antigens and glycoconjugates thereof |
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| KR102205620B1 (ko) | 2019-05-16 | 2021-01-21 | 한국과학기술연구원 | 혈중 내 극소량 존재하는 miRNA의 검출 효율의 증가 방법 |
| CN110256556A (zh) * | 2019-06-28 | 2019-09-20 | 成都欧林生物科技股份有限公司 | 一种耐甲氧西林金黄色葡萄球菌人免疫球蛋白及制备方法 |
| US20230045642A1 (en) * | 2019-12-19 | 2023-02-09 | Glaxosmithkline Biologicals Sa | S. aureus antigens and compositions thereof |
| CN115720521A (zh) * | 2019-12-31 | 2023-02-28 | 安踏格尼斯公司 | 用于预防金黄色葡萄球菌感染的组合物和方法 |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| WO2022081750A1 (en) | 2020-10-14 | 2022-04-21 | George Mason Research Foundation, Inc. | Ionizable lipids and methods of manufacture and use thereof |
| CN112851770B (zh) * | 2021-02-05 | 2022-10-04 | 中国人民解放军陆军军医大学 | 一种用于诊断或防治金黄色葡萄球菌感染的α溶血素抗原表位肽及其应用 |
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