ES2549303T3 - Anticuerpos monoclonales inmunomoduladores humanizados para el tratamiento de enfermedad neoplásica o inmunodeficiencia - Google Patents
Anticuerpos monoclonales inmunomoduladores humanizados para el tratamiento de enfermedad neoplásica o inmunodeficiencia Download PDFInfo
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- ES2549303T3 ES2549303T3 ES03723038.0T ES03723038T ES2549303T3 ES 2549303 T3 ES2549303 T3 ES 2549303T3 ES 03723038 T ES03723038 T ES 03723038T ES 2549303 T3 ES2549303 T3 ES 2549303T3
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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| PCT/IL2003/000425 WO2003099196A2 (en) | 2002-05-23 | 2003-05-22 | Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency |
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| US12370263B2 (en) | 2018-09-06 | 2025-07-29 | Daiichi Sankyo Company, Limited | Cyclic dinucleotide derivative based antibody-drug conjugates |
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| WO2025121445A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025120866A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025120867A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies |
| CN119841936B (zh) * | 2024-12-30 | 2025-09-30 | 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) | 抗非洲猪瘟病毒p72蛋白中和性单克隆抗体5d2及其应用 |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| CA2164646A1 (en) | 1993-06-11 | 1994-12-22 | Wade E. Bolton | Anti-cd3 antibody-aminodextran conjugates for induction of t-cell activation and proliferation |
| IL108501A (en) * | 1994-01-31 | 1998-10-30 | Mor Research Applic Ltd | Antibodies and pharmaceutical compositions containing them |
| GB9416657D0 (en) | 1994-08-17 | 1994-10-12 | Biocine Spa | T cell activation |
| GB9501079D0 (en) | 1995-01-19 | 1995-03-08 | Bioinvent Int Ab | Activation of T-cells |
| IL129299A0 (en) | 1999-03-31 | 2000-02-17 | Mor Research Applic Ltd | Monoclonal antibodies antigens and diagnosis of malignant diseases |
| IL145926A0 (en) * | 2001-10-15 | 2002-07-25 | Mor Research Applic Ltd | Peptide epitopes of mimotopes useful in immunomodulation |
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2002
- 2002-05-23 IL IL14982002A patent/IL149820A0/xx unknown
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- 2003-05-22 PT PT37230380T patent/PT1575484E/pt unknown
- 2003-05-22 ES ES03723038.0T patent/ES2549303T3/es not_active Expired - Lifetime
- 2003-05-22 WO PCT/IL2003/000425 patent/WO2003099196A2/en not_active Ceased
- 2003-05-22 AU AU2003230183A patent/AU2003230183B2/en not_active Ceased
- 2003-05-22 JP JP2004506723A patent/JP4764627B2/ja not_active Expired - Fee Related
- 2003-05-22 DK DK03723038.0T patent/DK1575484T3/en active
- 2003-05-22 SI SI200332448T patent/SI1575484T1/sl unknown
- 2003-05-22 KR KR1020047018962A patent/KR101169254B1/ko not_active Expired - Fee Related
- 2003-05-22 HU HUE03723038A patent/HUE025710T2/en unknown
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- 2003-05-22 EP EP03723038.0A patent/EP1575484B1/en not_active Expired - Lifetime
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- 2004-11-19 US US10/994,091 patent/US7332582B2/en not_active Expired - Lifetime
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- 2007-09-12 US US11/854,160 patent/US7524498B2/en not_active Expired - Lifetime
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- 2009-03-18 US US12/406,492 patent/US7981416B2/en not_active Expired - Lifetime
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- 2010-09-05 IL IL207985A patent/IL207985A/en active IP Right Grant
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12370263B2 (en) | 2018-09-06 | 2025-07-29 | Daiichi Sankyo Company, Limited | Cyclic dinucleotide derivative based antibody-drug conjugates |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2487060C (en) | 2011-01-04 |
| EP1575484A4 (en) | 2006-11-22 |
| CA2487060A1 (en) | 2003-12-04 |
| EP1575484A2 (en) | 2005-09-21 |
| WO2003099196A3 (en) | 2005-07-28 |
| KR20050008736A (ko) | 2005-01-21 |
| IL207985A0 (en) | 2010-12-30 |
| SI1575484T1 (sl) | 2015-11-30 |
| US7981416B2 (en) | 2011-07-19 |
| KR101169254B1 (ko) | 2012-08-03 |
| JP2011139708A (ja) | 2011-07-21 |
| PT1575484E (pt) | 2015-11-02 |
| AU2003230183A1 (en) | 2003-12-12 |
| IL207985A (en) | 2013-10-31 |
| JP4764627B2 (ja) | 2011-09-07 |
| AU2003230183B2 (en) | 2009-01-22 |
| US7524498B2 (en) | 2009-04-28 |
| IL165193A0 (en) | 2005-12-18 |
| US20090263386A1 (en) | 2009-10-22 |
| US7332582B2 (en) | 2008-02-19 |
| US20080025980A1 (en) | 2008-01-31 |
| JP2006505244A (ja) | 2006-02-16 |
| DK1575484T3 (en) | 2015-10-12 |
| IL149820A0 (en) | 2002-11-10 |
| EP1575484B1 (en) | 2015-07-08 |
| HUE025710T2 (en) | 2016-04-28 |
| WO2003099196A2 (en) | 2003-12-04 |
| CY1117114T1 (el) | 2017-04-05 |
| IL165193A (en) | 2010-12-30 |
| US20050180969A1 (en) | 2005-08-18 |
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