ES2387203T3 - Variantes de fitasa - Google Patents

Variantes de fitasa Download PDF

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Publication number
ES2387203T3
ES2387203T3 ES07711278T ES07711278T ES2387203T3 ES 2387203 T3 ES2387203 T3 ES 2387203T3 ES 07711278 T ES07711278 T ES 07711278T ES 07711278 T ES07711278 T ES 07711278T ES 2387203 T3 ES2387203 T3 ES 2387203T3
Authority
ES
Spain
Prior art keywords
phytase
seq
activity
polypeptide
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07711278T
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English (en)
Spanish (es)
Inventor
Leonardo De Maria
Carsten Andersen
Lars Kobberoee Skov
Mikael Blom Soerensen
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Novozymes AS
Original Assignee
Novozymes AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes AS filed Critical Novozymes AS
Application granted granted Critical
Publication of ES2387203T3 publication Critical patent/ES2387203T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
ES07711278T 2006-04-04 2007-03-19 Variantes de fitasa Active ES2387203T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200600484 2006-04-04
DK200600484 2006-04-04
DK200600581 2006-04-25
DKPA200600581 2006-04-25
PCT/DK2007/000135 WO2007112739A1 (en) 2006-04-04 2007-03-19 Phytase variants

Publications (1)

Publication Number Publication Date
ES2387203T3 true ES2387203T3 (es) 2012-09-17

Family

ID=38123737

Family Applications (2)

Application Number Title Priority Date Filing Date
ES07711278T Active ES2387203T3 (es) 2006-04-04 2007-03-19 Variantes de fitasa
ES11155829.2T Active ES2531434T3 (es) 2006-04-04 2007-03-19 Variantes de fitasa

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES11155829.2T Active ES2531434T3 (es) 2006-04-04 2007-03-19 Variantes de fitasa

Country Status (11)

Country Link
US (4) US8460656B2 (cg-RX-API-DMAC7.html)
EP (2) EP2365064B1 (cg-RX-API-DMAC7.html)
JP (1) JP5221516B2 (cg-RX-API-DMAC7.html)
AU (1) AU2007234177B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0709732B1 (cg-RX-API-DMAC7.html)
CA (1) CA2647476C (cg-RX-API-DMAC7.html)
DK (1) DK2365064T3 (cg-RX-API-DMAC7.html)
ES (2) ES2387203T3 (cg-RX-API-DMAC7.html)
MX (1) MX2008012632A (cg-RX-API-DMAC7.html)
PL (1) PL2365064T3 (cg-RX-API-DMAC7.html)
WO (1) WO2007112739A1 (cg-RX-API-DMAC7.html)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
PL2365064T3 (pl) 2006-04-04 2015-05-29 Novozymes As Warianty fitazy
US8540984B2 (en) 2006-08-03 2013-09-24 Cornell Research Foundation, Inc. Phytases with improved thermal stability
WO2008036916A2 (en) 2006-09-21 2008-03-27 Verenium Corporation Phytases, nucleic acids encoding them and methods for making and using them
CN102165059A (zh) 2008-09-26 2011-08-24 诺维信公司 哈夫尼菌属肌醇六磷酸酶变体
US20110318454A1 (en) 2009-03-20 2011-12-29 Novozymes A/S Nutritional beverage and a method of making the same
BRPI1011160A8 (pt) 2009-05-21 2018-01-02 Verenium Corp Fitases, preparação de proteína que as compreende, e seus usos
AU2013204082B2 (en) * 2009-05-21 2016-03-31 Basf Enzymes Llc Phytases, nucleic acids encoding them and methods for making and using them
EP2491120B1 (de) 2009-10-22 2015-12-23 Basf Se Synthetische phytasevarianten
RU2472855C2 (ru) * 2009-12-15 2013-01-20 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП ГосНИИгенетика) МУТАНТНАЯ РЕКОМБИНАНТНАЯ ТЕРМОСТАБИЛЬНАЯ ФИТАЗА (ВАРИАНТЫ), ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ УКАЗАННУЮ ФИТАЗУ (ВАРИАНТЫ), ШТАММ Pichia pastoris - ПРОДУЦЕНТ УКАЗАННОЙ ФИТАЗЫ (ВАРИАНТЫ)
EP2553091B1 (en) * 2010-03-26 2019-05-08 Novozymes A/S Thermostable phytase variants
WO2011117396A2 (en) * 2010-03-26 2011-09-29 Novozymes A/S Thermostable phytase variants
WO2011117397A1 (en) * 2010-03-26 2011-09-29 Novozymes A/S Thermostable phytase variants
GB201102857D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
GB201102865D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
PL2675287T3 (pl) * 2011-02-18 2017-01-31 Dupont Nutrition Biosciences Aps Kompozycja dodatku paszowego
DK2699674T3 (da) 2011-04-21 2016-03-21 Basf Se Syntetiske fytasevarianter
JP5872024B2 (ja) 2011-04-21 2016-03-01 ビーエーエスエフ ソシエタス・ヨーロピアBasf Se 合成フィターゼ変異体
MX2013014757A (es) 2011-07-07 2014-02-11 Dupont Nutrition Biosci Aps Ensayo.
GB201213801D0 (en) 2012-08-03 2012-09-12 Dupont Nutrition Biosci Aps Feed additive composition
ES2738181T3 (es) 2013-03-08 2020-01-20 Keck Graduate Inst Of Applied Life Sciences Promotores de levadura de Pichia pastoris
EP3839055B1 (en) * 2013-03-08 2023-08-23 Biogrammatics, Inc. Yeast promoters for protein expression
WO2015035914A1 (en) 2013-09-11 2015-03-19 Novozymes A/S Processes for producing fermentation products
EP3160260B1 (en) 2014-06-27 2020-05-27 DSM IP Assets B.V. A method for improving the nutritional value of animal feed
AU2016288468B2 (en) * 2015-07-02 2020-07-16 Dsm Ip Assets B.V. Animal feed compositions and uses thereof
CN108699570A (zh) 2015-12-22 2018-10-23 诺维信公司 从酒糟水提取油的工艺
TWI615471B (zh) * 2016-02-18 2018-02-21 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI607088B (zh) * 2016-02-18 2017-12-01 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI616532B (zh) * 2016-02-18 2018-03-01 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI591180B (zh) 2016-02-18 2017-07-11 基酵生物科技股份有限公司 提升耐熱性的植酸酶
US12227784B2 (en) 2017-09-15 2025-02-18 Novozymes A/S Enzyme blends and processes for improving the nutritional quality of animal feed
CN111183228A (zh) 2017-10-23 2020-05-19 诺维信公司 减少生物燃料发酵系统中乳酸的方法
MX2020008302A (es) 2018-02-08 2020-10-14 Danisco Us Inc Partículas de matriz de cera térmicamente resistentes para encapsulación de enzimas.
JP2021521835A (ja) 2018-04-26 2021-08-30 ダニスコ・ユーエス・インク 固体組成物中のフィターゼの安定性を増加させる方法、並びにリン酸塩及びフィターゼを含む顆粒組成物
CA3098718A1 (en) 2018-05-31 2019-12-05 Novozymes A/S Processes for enhancing yeast growth and productivity
RU2706086C1 (ru) * 2018-10-29 2019-11-13 Акционерное Общество "Биоамид" Мутантная рекомбинантная термостабильная фитаза
CA3118924A1 (en) 2018-11-09 2020-05-14 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides
JP7569523B2 (ja) 2018-11-20 2024-10-18 インターナショナル エヌアンドエイチ デンマーク エーピーエス 改変ロバスト高Tm-フィターゼ分岐群ポリペプチド及びその断片
BR112021014873A2 (pt) 2019-01-31 2021-10-05 Novozymes A/S Polipeptídeo, combinação de enzimas, polinucleotídeo, construto de ácido nucleico ou vetor de expressão recombinante, célula hospedeira recombinante, método de produção de um polipeptídeo, e, processo de produção de um produto de fermentação
BR112022000351A2 (pt) 2019-07-09 2022-05-10 Dupont Nutrition Biosci Aps Composições de enzima particuladas revestidas de gordura
BR112022002203A2 (pt) 2019-08-05 2022-09-06 Novozymes As Misturas de enzimas e processos para produção de um ingrediente alimentar com alto teor de proteína a partir de um subproduto de vinhaça completa
US20220330576A1 (en) 2019-08-16 2022-10-20 Dupont Nutrition Biosciences Aps Compositions for gut health
WO2021046073A1 (en) 2019-09-05 2021-03-11 Dupont Nutrition Biosciences Aps Feed composition
CN114828642B (zh) 2019-10-21 2024-12-13 国际N&H丹麦有限公司 用于消化道健康的组合物
US20230023446A1 (en) 2019-12-16 2023-01-26 Novozymes A/S Processes for producing fermentation products
CN115867146B (zh) 2020-02-07 2025-01-17 国际N&H丹麦有限公司 用于动物健康的饲料组合物
CN115915956A (zh) 2020-02-28 2023-04-04 杜邦营养生物科学有限公司 饲料组合物
MX2023001397A (es) 2020-08-13 2023-03-03 Novozymes As Variantes de fitasa y polinucleotidos que codifican las mismas.
WO2022081947A1 (en) 2020-10-16 2022-04-21 Dupont Nutrition Biosciences Feed compositions for animal health
WO2022169933A2 (en) 2021-02-03 2022-08-11 Dupont Nutrition Biosciences Aps Compositions for gut health
EP4408186A1 (en) 2021-09-27 2024-08-07 International N&H Denmark ApS Feed additive compositions and methods for using the same
EP4638727A1 (en) 2022-12-19 2025-10-29 Novozymes A/S Compositions comprising arabinofuranosidases and a xylanase, and use thereof for increasing hemicellulosic fiber solubilization
EP4638724A1 (en) 2022-12-19 2025-10-29 Novozymes A/S Carbohydrate esterase family 1 (ce1) polypeptides having ferulic acid esterase and/or acetyl xylan esterase activity and polynucleotides encoding same
CN120283060A (zh) 2022-12-19 2025-07-08 诺维信公司 用于使用纤维降解酶和工程化酵母生产发酵产物的工艺
EP4638767A1 (en) 2022-12-19 2025-10-29 Novozymes A/S Process for reducing syrup viscosity in the backend of a process for producing a fermentation product
CN120380139A (zh) 2022-12-19 2025-07-25 诺维信公司 具有乙酰木聚糖酯酶活性的碳水化合物酯酶家族3(ce3)多肽和编码其的多核苷酸
WO2024227153A1 (en) 2023-04-28 2024-10-31 International N&H Denmark Aps Ruminant feed additive compositions
AU2024303961A1 (en) 2023-06-13 2025-12-11 Novozymes A/S Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase
WO2025059013A1 (en) 2023-09-11 2025-03-20 International N&H Denmark Aps Bacillus-based components for inhibiting or delaying the growth of enterococcus spp. in animals
WO2025128568A1 (en) 2023-12-11 2025-06-19 Novozymes A/S Composition and use thereof for increasing hemicellulosic fiber solubilization
WO2025217017A1 (en) 2024-04-08 2025-10-16 Novozymes A/S Compositions and methods for increasing phosphorous availability

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
PT97110B (pt) 1990-03-23 1998-11-30 Gist Brocades Nv Processo para catalisar reaccoes acelaraveis por enzimas, mediante adicao ao meio reaccional de sementes de plantas transgenicas e para obtencao das referidas sementes
WO1992010755A1 (en) 1990-12-05 1992-06-25 Novo Nordisk A/S Proteins with changed epitopes and methods for the production thereof
DK91192D0 (da) 1992-07-10 1992-07-10 Novo Nordisk As Protein
JPH0795946B2 (ja) 1993-08-19 1995-10-18 イチビキ株式会社 フィターゼ及びその製造法
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5689054A (en) 1994-03-17 1997-11-18 The United States Of America As Represented By The Secretary Of Agriculture Low phytic acid mutants and selection thereof
DE4422198C2 (de) 1994-06-24 1997-08-28 Audi Ag Verfahren zum Steuern der elektrischen Beheizung eines Katalysators
EP1559776A3 (en) 1994-06-30 2006-01-11 Novozymes Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic Fusarium expression system and promoters and terminators for use therein
JP3570784B2 (ja) * 1994-07-05 2004-09-29 三井化学株式会社 新規なるフィターゼ
US5830732A (en) 1994-07-05 1998-11-03 Mitsui Toatsu Chemicals, Inc. Phytase
EP0793726A1 (en) 1994-11-24 1997-09-10 Novo Nordisk A/S A process for producing polypeptides with reduced allergenicity
MX9704137A (es) 1994-12-07 1997-09-30 Novo Nordisk As Polipeptidos de alergenicidad reducida.
JP2002510963A (ja) 1997-01-10 2002-04-09 ノボザイムス アクティーゼルスカブ スキンケア用酵素修飾体
AU740207B2 (en) 1997-02-06 2001-11-01 Novozymes A/S Polypeptide-polymer conjugates having added and/or removed attachment groups
ATE375387T1 (de) 1997-06-25 2007-10-15 Novozymes As Modifiziertes polypeptid
NZ330940A (en) * 1997-07-24 2000-02-28 F Production of consensus phytases from fungal origin using computer programmes
US6720014B1 (en) * 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US5955310A (en) 1998-02-26 1999-09-21 Novo Nordisk Biotech, Inc. Methods for producing a polypeptide in a bacillus cell
KR20010042138A (ko) 1998-03-23 2001-05-25 피아 스타르 피타제 변이체
JP4455764B2 (ja) 1998-10-02 2010-04-21 ノボザイムス アクティーゼルスカブ 固体フィターゼ組成物
EP1121424A1 (en) 1998-10-13 2001-08-08 Novozymes A/S A modified polypeptide with reduced immune response
DE69938435D1 (de) 1998-10-30 2008-05-08 Novozymes As Niedrigallergene Proteinvarianten
ES2289824T3 (es) 1998-10-30 2008-02-01 Novozymes A/S Proteinas glicosiladas con alergenicidad reducida.
CN100379860C (zh) 1999-04-23 2008-04-09 圭尔夫大学 表达唾液蛋白的转基因动物
JP2003531574A (ja) * 1999-11-18 2003-10-28 コーネル リサーチ ファウンデーション、インコーポレイティッド 大腸菌フィターゼの部位特異的変異誘発
CA2395343C (en) 2000-02-08 2009-06-30 F. Hoffmann-La Roche Ag Use of acid-stable proteases in animal feed
AU2001254623A1 (en) 2000-04-28 2001-11-12 Novozymes A/S Production and use of protein variants having modified immunogenicity
US7319087B2 (en) 2001-05-04 2008-01-15 Novozymes A/S Antimicrobial polypeptide from Aspergillus niger
WO2003044049A1 (en) 2001-11-20 2003-05-30 Novozymes A/S Antimicrobial polypeptides from pseudoplectania nigrella
JP2005513042A (ja) 2001-12-03 2005-05-12 ノボザイムス アクティーゼルスカブ スタチン様化合物
PL372824A1 (en) 2002-05-30 2005-08-08 Basf Aktiengesellschaft Modified phytases
DK1546316T3 (da) * 2002-08-12 2011-02-14 Danisco Us Inc Mutant E. Coli-AppA-fytaseenzymer og naturlige varianter deraf, nukleinsyrer, der koder for sådanne fytaseenzymer, vektorer og værtsceller, som inkorporerer disse og fremgangsmåder til at fremstille og anvende disse
US7442398B2 (en) * 2003-03-25 2008-10-28 Republic Of National Fisheries Research And Development Institute Phytase produced from Citrobacter braakii
JP2005137293A (ja) 2003-11-07 2005-06-02 Mitsui Chemicals Inc コドン改変と細胞外分泌の組合せにより外来フィターゼを植物で生産する方法
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
PL1797178T3 (pl) * 2004-10-04 2013-02-28 Dupont Nutrition Biosci Aps Fitaza pochodząca od Citrobacter freundii i jej homologi
AR050895A1 (es) * 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
JP5221137B2 (ja) * 2004-10-04 2013-06-26 ノボザイムス アクティーゼルスカブ フィターゼ活性を有するポリペプチド及びそれをコードするポリヌクレオチド
JP2006136314A (ja) 2004-10-12 2006-06-01 Mitsui Chemicals Inc 新規改変フィターゼ
KR100663112B1 (ko) * 2004-10-29 2007-01-02 주식회사 기성기전 절전형 전자개폐기
WO2006063588A1 (en) 2004-12-13 2006-06-22 Novozymes A/S Polypeptides having acid phosphatase activity and polynucleotides encoding same
FR2888250B1 (fr) * 2005-07-08 2007-08-17 Adisseo France Sas Soc Par Act Phytase de debaryomyces castellii
PL2365064T3 (pl) 2006-04-04 2015-05-29 Novozymes As Warianty fitazy

Also Published As

Publication number Publication date
EP2001999A1 (en) 2008-12-17
EP2365064A1 (en) 2011-09-14
AU2007234177B2 (en) 2012-11-08
US10041052B2 (en) 2018-08-07
CA2647476C (en) 2016-08-16
AU2007234177A1 (en) 2007-10-11
ES2531434T3 (es) 2015-03-16
BRPI0709732A2 (pt) 2011-07-26
US20130224332A1 (en) 2013-08-29
WO2007112739A1 (en) 2007-10-11
JP5221516B2 (ja) 2013-06-26
US8877471B2 (en) 2014-11-04
EP2365064B1 (en) 2014-12-24
MX2008012632A (es) 2008-10-13
PL2365064T3 (pl) 2015-05-29
JP2009532043A (ja) 2009-09-10
US20150024084A1 (en) 2015-01-22
EP2001999B1 (en) 2012-05-16
CA2647476A1 (en) 2007-10-11
US8460656B2 (en) 2013-06-11
US20160362666A1 (en) 2016-12-15
DK2365064T3 (en) 2015-03-30
US9451783B2 (en) 2016-09-27
BRPI0709732B1 (pt) 2017-06-06
US20110258714A1 (en) 2011-10-20

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