ES2371361T3 - Composiciones que comprenden una insulina acilada y zinc y método de producción de dichas composiciones. - Google Patents
Composiciones que comprenden una insulina acilada y zinc y método de producción de dichas composiciones. Download PDFInfo
- Publication number
- ES2371361T3 ES2371361T3 ES06841562T ES06841562T ES2371361T3 ES 2371361 T3 ES2371361 T3 ES 2371361T3 ES 06841562 T ES06841562 T ES 06841562T ES 06841562 T ES06841562 T ES 06841562T ES 2371361 T3 ES2371361 T3 ES 2371361T3
- Authority
- ES
- Spain
- Prior art keywords
- insulin
- chain
- zinc
- acylated
- desb30
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Immunology (AREA)
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- Emergency Medicine (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05113021 | 2005-12-28 | ||
| EP05113021 | 2005-12-28 |
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| ES2371361T3 true ES2371361T3 (es) | 2011-12-30 |
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| ES06841562T Active ES2371361T3 (es) | 2005-12-28 | 2006-12-21 | Composiciones que comprenden una insulina acilada y zinc y método de producción de dichas composiciones. |
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|---|---|
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| EP (2) | EP2505593A1 (enExample) |
| JP (3) | JP4808785B2 (enExample) |
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| AT (1) | ATE519780T1 (enExample) |
| DK (1) | DK1969004T3 (enExample) |
| ES (1) | ES2371361T3 (enExample) |
| PL (1) | PL1969004T3 (enExample) |
| PT (1) | PT1969004E (enExample) |
| WO (1) | WO2007074133A2 (enExample) |
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|---|---|---|---|---|
| CA2531988C (en) | 2003-08-05 | 2016-06-28 | Novo Nordisk A/S | Novel insulin derivatives |
| WO2006051103A2 (en) * | 2004-11-12 | 2006-05-18 | Novo Nordisk A/S | Stable formulations of peptides |
| EP2256130B1 (en) | 2005-02-02 | 2013-09-25 | Novo Nordisk A/S | Novel insulin derivatives |
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| US10919949B2 (en) | 2017-08-17 | 2021-02-16 | Novo Nordisk A/S | Acylated insulin analogues and uses thereof |
-
2006
- 2006-12-21 ES ES06841562T patent/ES2371361T3/es active Active
- 2006-12-21 PL PL06841562T patent/PL1969004T3/pl unknown
- 2006-12-21 PT PT06841562T patent/PT1969004E/pt unknown
- 2006-12-21 JP JP2008547953A patent/JP4808785B2/ja active Active
- 2006-12-21 DK DK06841562.9T patent/DK1969004T3/da active
- 2006-12-21 CN CN2006800535166A patent/CN101389650B/zh not_active Ceased
- 2006-12-21 AT AT06841562T patent/ATE519780T1/de active
- 2006-12-21 EP EP11156145A patent/EP2505593A1/en not_active Withdrawn
- 2006-12-21 WO PCT/EP2006/070104 patent/WO2007074133A2/en not_active Ceased
- 2006-12-21 EP EP06841562A patent/EP1969004B1/en active Active
- 2006-12-21 US US12/096,476 patent/US20090074882A1/en not_active Abandoned
-
2010
- 2010-08-02 JP JP2010174030A patent/JP5026567B2/ja active Active
-
2011
- 2011-01-19 JP JP2011008924A patent/JP2011121963A/ja not_active Withdrawn
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2014
- 2014-07-16 US US14/332,906 patent/US11167035B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20140328943A1 (en) | 2014-11-06 |
| PL1969004T3 (pl) | 2012-01-31 |
| EP1969004B1 (en) | 2011-08-10 |
| JP2011121963A (ja) | 2011-06-23 |
| CN101389650A (zh) | 2009-03-18 |
| PT1969004E (pt) | 2011-11-25 |
| DK1969004T3 (da) | 2011-11-28 |
| JP2009522231A (ja) | 2009-06-11 |
| US11167035B2 (en) | 2021-11-09 |
| JP2011006428A (ja) | 2011-01-13 |
| EP1969004A2 (en) | 2008-09-17 |
| JP4808785B2 (ja) | 2011-11-02 |
| EP2505593A1 (en) | 2012-10-03 |
| JP5026567B2 (ja) | 2012-09-12 |
| CN101389650B (zh) | 2012-10-10 |
| ATE519780T1 (de) | 2011-08-15 |
| US20090074882A1 (en) | 2009-03-19 |
| WO2007074133A3 (en) | 2007-10-11 |
| WO2007074133A2 (en) | 2007-07-05 |
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