ES2283425T3 - Nueva composicion para la administracion transdermica y/o transmucosa de compuestos activos que asegura niveles terapeutiocos adecuados. - Google Patents
Nueva composicion para la administracion transdermica y/o transmucosa de compuestos activos que asegura niveles terapeutiocos adecuados. Download PDFInfo
- Publication number
- ES2283425T3 ES2283425T3 ES01960619T ES01960619T ES2283425T3 ES 2283425 T3 ES2283425 T3 ES 2283425T3 ES 01960619 T ES01960619 T ES 01960619T ES 01960619 T ES01960619 T ES 01960619T ES 2283425 T3 ES2283425 T3 ES 2283425T3
- Authority
- ES
- Spain
- Prior art keywords
- transdermal
- penetration
- gel
- testosterone
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Physiology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| WOPCT/EP00/07533 | 2000-08-03 | ||
| EP0007533 | 2000-08-03 | ||
| PCT/EP2001/009007 WO2002011768A1 (en) | 2000-08-03 | 2001-08-03 | Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2283425T3 true ES2283425T3 (es) | 2007-11-01 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| ES01960619T Expired - Lifetime ES2283425T3 (es) | 2000-08-03 | 2001-08-03 | Nueva composicion para la administracion transdermica y/o transmucosa de compuestos activos que asegura niveles terapeutiocos adecuados. |
| ES03003313T Expired - Lifetime ES2283665T3 (es) | 2000-08-03 | 2001-08-03 | Composicion para administracion transdermica y/o transmucosa de compuestos activos que asegura unos niveles terapeuticamente adecuados. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03003313T Expired - Lifetime ES2283665T3 (es) | 2000-08-03 | 2001-08-03 | Composicion para administracion transdermica y/o transmucosa de compuestos activos que asegura unos niveles terapeuticamente adecuados. |
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| Country | Link |
|---|---|
| US (2) | US7214381B2 (enExample) |
| EP (4) | EP1323431B1 (enExample) |
| JP (1) | JP2004505931A (enExample) |
| KR (1) | KR100856523B1 (enExample) |
| AR (1) | AR030312A1 (enExample) |
| AT (3) | ATE356636T1 (enExample) |
| AU (2) | AU2001282064B2 (enExample) |
| CA (1) | CA2418135C (enExample) |
| DE (3) | DE60127134T2 (enExample) |
| ES (2) | ES2283425T3 (enExample) |
| NZ (1) | NZ524423A (enExample) |
| WO (1) | WO2002011768A1 (enExample) |
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| US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
| US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
| ATE356636T1 (de) | 2000-08-03 | 2007-04-15 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert |
| US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| US20070225379A1 (en) * | 2001-08-03 | 2007-09-27 | Carrara Dario Norberto R | Transdermal delivery of systemically active central nervous system drugs |
| US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| SK7932003A3 (en) * | 2000-12-22 | 2003-11-04 | August Wolff Gmbh & Co Dr | Gel composition and trans-scrotal application of a composition for the treatment of hypogonadism |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| MY139721A (en) * | 2002-04-19 | 2009-10-30 | Cpex Pharmaceuticals Inc | Pharmaceutical composition |
| FR2851470B1 (fr) | 2003-02-20 | 2007-11-16 | Besins Int Belgique | Composition pharmaceutique pour administration transdermique ou transmuqueuse |
| US7858607B2 (en) | 2003-03-14 | 2010-12-28 | Mamchur Stephen A | System for use by compounding pharmacists to produce hormone replacement medicine customized for each consumer |
| US20040259852A1 (en) * | 2003-06-18 | 2004-12-23 | White Hillary D. | Trandsdermal compositions and methods for treatment of fibromyalgia and chronic fatigue syndrome |
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| MXPA06003316A (es) * | 2003-10-10 | 2006-06-08 | Antares Pharma Ipl Ag | Formulacion farmaceutica transdermica para minimizar los residuos en la piel. |
| US7425340B2 (en) | 2004-05-07 | 2008-09-16 | Antares Pharma Ipl Ag | Permeation enhancing compositions for anticholinergic agents |
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| US8927537B2 (en) * | 2007-12-21 | 2015-01-06 | Nuvo Research Inc. | Patches, formulations, and associated methods for transdermal delivery of alprazolam and other drugs |
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-
2001
- 2001-08-03 AT AT03003313T patent/ATE356636T1/de not_active IP Right Cessation
- 2001-08-03 EP EP03003316A patent/EP1323431B1/en not_active Expired - Lifetime
- 2001-08-03 EP EP03003317A patent/EP1325752A3/en not_active Withdrawn
- 2001-08-03 AT AT01960619T patent/ATE355854T1/de not_active IP Right Cessation
- 2001-08-03 WO PCT/EP2001/009007 patent/WO2002011768A1/en not_active Ceased
- 2001-08-03 CA CA2418135A patent/CA2418135C/en not_active Expired - Fee Related
- 2001-08-03 ES ES01960619T patent/ES2283425T3/es not_active Expired - Lifetime
- 2001-08-03 DE DE60127134T patent/DE60127134T2/de not_active Expired - Lifetime
- 2001-08-03 NZ NZ524423A patent/NZ524423A/en not_active IP Right Cessation
- 2001-08-03 EP EP01960619A patent/EP1307232B1/en not_active Expired - Lifetime
- 2001-08-03 EP EP03003313A patent/EP1323430B1/en not_active Expired - Lifetime
- 2001-08-03 ES ES03003313T patent/ES2283665T3/es not_active Expired - Lifetime
- 2001-08-03 AR ARP010103720A patent/AR030312A1/es not_active Application Discontinuation
- 2001-08-03 KR KR1020037001526A patent/KR100856523B1/ko not_active Expired - Fee Related
- 2001-08-03 AU AU2001282064A patent/AU2001282064B2/en not_active Ceased
- 2001-08-03 US US10/343,570 patent/US7214381B2/en not_active Expired - Fee Related
- 2001-08-03 DE DE60143360T patent/DE60143360D1/de not_active Expired - Lifetime
- 2001-08-03 AU AU8206401A patent/AU8206401A/xx active Pending
- 2001-08-03 DE DE60127277T patent/DE60127277T2/de not_active Expired - Lifetime
- 2001-08-03 AT AT03003316T patent/ATE485837T1/de not_active IP Right Cessation
- 2001-08-03 JP JP2002517102A patent/JP2004505931A/ja active Pending
-
2006
- 2006-12-04 US US11/634,005 patent/US7404965B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NZ524423A (en) | 2004-04-30 |
| AU8206401A (en) | 2002-02-18 |
| DE60127134D1 (de) | 2007-04-19 |
| EP1323431A2 (en) | 2003-07-02 |
| DE60127277T2 (de) | 2007-11-29 |
| EP1325752A3 (en) | 2003-08-06 |
| US20030199426A1 (en) | 2003-10-23 |
| EP1323430B1 (en) | 2007-03-14 |
| DE60127134T2 (de) | 2007-11-08 |
| EP1325752A2 (en) | 2003-07-09 |
| KR100856523B1 (ko) | 2008-09-04 |
| US7214381B2 (en) | 2007-05-08 |
| CA2418135C (en) | 2011-09-20 |
| US20070098775A1 (en) | 2007-05-03 |
| EP1323431A3 (en) | 2003-08-06 |
| AR030312A1 (es) | 2003-08-20 |
| US7404965B2 (en) | 2008-07-29 |
| ES2283665T3 (es) | 2007-11-01 |
| AU2001282064B2 (en) | 2007-02-01 |
| EP1323430A3 (en) | 2003-08-06 |
| WO2002011768A1 (en) | 2002-02-14 |
| ATE355854T1 (de) | 2007-03-15 |
| DE60143360D1 (de) | 2010-12-09 |
| KR20030031568A (ko) | 2003-04-21 |
| EP1323431B1 (en) | 2010-10-27 |
| EP1323430A2 (en) | 2003-07-02 |
| ATE485837T1 (de) | 2010-11-15 |
| EP1307232A1 (en) | 2003-05-07 |
| DE60127277D1 (de) | 2007-04-26 |
| CA2418135A1 (en) | 2002-02-14 |
| ATE356636T1 (de) | 2007-04-15 |
| JP2004505931A (ja) | 2004-02-26 |
| EP1307232B1 (en) | 2007-03-07 |
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