AR068408A1 - Pulverizacion de hormonas transdermicas - Google Patents
Pulverizacion de hormonas transdermicasInfo
- Publication number
- AR068408A1 AR068408A1 ARP080103941A ARP080103941A AR068408A1 AR 068408 A1 AR068408 A1 AR 068408A1 AR P080103941 A ARP080103941 A AR P080103941A AR P080103941 A ARP080103941 A AR P080103941A AR 068408 A1 AR068408 A1 AR 068408A1
- Authority
- AR
- Argentina
- Prior art keywords
- branched
- linear
- substituted
- alkyl group
- cyclic chain
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
Abstract
Una composicion de pulverizacion transdérmica de estrogenos, que comprende: una cantidad terapéuticamente eficaz de un estrogeno; un potenciador de la penetracion; y un disolvente volátil, donde el potenciador de la penetracion se selecciona entre terpenos, terpenoides, aceites esenciales, pirrolidonas, azonas sulfoxidos, amidas, alcoholes, glicoles, glicéridos, derivados de aminoácidos, fosfolípidos, tensioactivos y ácidos grasos y ésteres de los mismos que tienen la formula (1) R1-C(=O)-O-H o formula (2) R2-C(=O)-R3 en la que: R1 se selecciona entre un grupo alquilo que contiene una cadena lineal, ramificada o cíclica o un grupo alquilo sustituido C8-20, y un grupo alquenilo que contiene una cadena lineal, ramificada o cíclica o un grupo alquenilo sustituido C8-20; R2 se selecciona entre un grupo alquilo que contiene una cadena lineal, ramificada o cíclica o un grupo alquilo sustituido C8-20, y un grupo alquenilo que contiene una cadena lineal, ramificada o cíclica o un grupo alquenilo sustituido C8-20; y R3 se selecciona entre alquilo inferior, alquenilo inferior, un grupo alquilo que contiene una cadena lineal, ramificada o cíclica o un grupo alquilo sustituido C6-14, y un grupo alquenilo que contiene una cadena lineal, ramificada o cíclica o un grupo alquenilo sustituido C6-14, y los alquilos sustituidos o alquenilos sustituidos tienen de 1 a 4 sustituyentes seleccionados entre hidroxi, halo, oxo, alcoxi y amino; y donde, cuando se aplica a la piel, la composicion proporciona un flujo transdérmico en vivo de estrogenos de aproximadamente 0,03 a aproximadamente 0,3microgramos/cm2 por hora.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99375507P | 2007-09-14 | 2007-09-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR068408A1 true AR068408A1 (es) | 2009-11-18 |
Family
ID=40452546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080103941A AR068408A1 (es) | 2007-09-14 | 2008-09-11 | Pulverizacion de hormonas transdermicas |
Country Status (6)
Country | Link |
---|---|
US (1) | US20090075963A1 (es) |
AR (1) | AR068408A1 (es) |
CA (1) | CA2699632A1 (es) |
CL (1) | CL2008002721A1 (es) |
PE (1) | PE20090680A1 (es) |
WO (1) | WO2009036355A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20110094858A (ko) * | 2010-02-18 | 2011-08-24 | 에스케이케미칼주식회사 | 피부 자극이 감소한 톨테로딘의 경피 투여용 조성물 |
GB201200062D0 (en) | 2012-01-04 | 2012-02-15 | Innotesto Bvba | Estradiol oromucosal liquid compositions |
MX2015008021A (es) | 2012-12-21 | 2016-03-04 | Teikoku Pharma Usa Inc | Composiciones y metodos para administracion transdermica de hormonas y otros agentes medicos. |
US11523994B2 (en) | 2018-01-10 | 2022-12-13 | Celista Pharmaceuticals Llc | Testosterone transdermal spray with film |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4978532A (en) * | 1989-08-11 | 1990-12-18 | Pharmedic Co. | Dosage form for administration of dehydroepiandrosterone |
US5198223A (en) * | 1990-10-29 | 1993-03-30 | Alza Corporation | Transdermal formulations, methods and devices |
US5304368A (en) * | 1993-02-19 | 1994-04-19 | American Telecast Corporation | Non-foaming, non-viscous, alcohol-free, water-based, pressurized hair spray product |
US5624060A (en) * | 1995-05-02 | 1997-04-29 | Ellion; M. Edmund | Invertible dispensing system and dip tube |
US6923983B2 (en) * | 1996-02-19 | 2005-08-02 | Acrux Dds Pty Ltd | Transdermal delivery of hormones |
US6929801B2 (en) * | 1996-02-19 | 2005-08-16 | Acrux Dds Pty Ltd | Transdermal delivery of antiparkinson agents |
US6916486B2 (en) * | 1996-02-19 | 2005-07-12 | Acrux Dds Pty Ltd | Transdermal delivery of analgesics |
US6916487B2 (en) * | 1996-02-19 | 2005-07-12 | Acrux Dds Pty Ltd | Transdermal delivery of antiemetics |
US6998138B2 (en) * | 1996-02-19 | 2006-02-14 | Acrux Dds Pty. Ltd. | Topical delivery of anti-alopecia agents |
US7094422B2 (en) * | 1996-02-19 | 2006-08-22 | Acrux Dds Pty Ltd. | Topical delivery of antifungal agents |
AUPN814496A0 (en) * | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
FR2758479B1 (fr) * | 1997-01-20 | 1999-03-26 | Valois | Dispositif pour distribuer un produit fluide ou pulverulent a une distance predeterminee |
US5912240A (en) * | 1997-04-10 | 1999-06-15 | Loria; Roger M. | 5-androstene 3β, 17α diol as an inhibitor of tumor growth |
US20040044080A1 (en) * | 1997-10-28 | 2004-03-04 | Place Virgil A. | Treatment of dyspareunia with topically administered nitroglycerin formulations |
US6113008A (en) * | 1998-08-20 | 2000-09-05 | 3M Innovative Properties Company | Actuator system for spraying a formulation onto a host |
WO2002011768A1 (en) * | 2000-08-03 | 2002-02-14 | Antares Pharma Ipl Ag | Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels |
AUPR184500A0 (en) * | 2000-12-01 | 2001-01-04 | Drug Delivery Solutions Pty Ltd | Dispensing device |
NZ537360A (en) * | 2002-06-25 | 2006-09-29 | Acrux Dds Pty Ltd | Transdermal delivery rate control using amorphous pharmaceutical compositions |
US20050181032A1 (en) * | 2002-06-25 | 2005-08-18 | Acrux Dds Pty Ltd. | Metastable pharmaceutical compositions |
US20050186141A1 (en) * | 2002-06-25 | 2005-08-25 | Acrux Dds Pty Ltd. | Transdermal aerosol compositions |
US7820145B2 (en) * | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
FR2856301B1 (fr) * | 2003-06-23 | 2007-08-03 | Galderma Res & Dev | Composition sous forme de spray comprenant un actif pharmaceutique, au moins un silicone volatile et une phase non polaire non volatile |
AU2004283431B2 (en) * | 2003-10-10 | 2009-09-10 | Antares Pharma Ipl Ag | Transdermal pharmaceutical formulation for minimizing skin residues |
CN1886171A (zh) * | 2003-11-28 | 2006-12-27 | 艾克若克斯Dds有限公司 | 快速经皮施用的方法和系统 |
CN1889994A (zh) * | 2003-12-10 | 2007-01-03 | 艾克若克斯Dds有限公司 | 伴随透皮或局部药物输送的不希望的效果的治疗方法 |
US20070189977A1 (en) * | 2004-06-07 | 2007-08-16 | Jie Zhang | Spray-on formulations and methods for dermal delivery of drugs |
PL2214643T3 (pl) * | 2007-11-02 | 2014-09-30 | Acrux Dds Pty Ltd | Układ transdermalnego dostarczania hormonów i steroidów |
-
2008
- 2008-09-11 AR ARP080103941A patent/AR068408A1/es unknown
- 2008-09-12 WO PCT/US2008/076273 patent/WO2009036355A1/en active Application Filing
- 2008-09-12 CL CL2008002721A patent/CL2008002721A1/es unknown
- 2008-09-12 PE PE2008001594A patent/PE20090680A1/es not_active Application Discontinuation
- 2008-09-12 CA CA2699632A patent/CA2699632A1/en not_active Abandoned
- 2008-09-12 US US12/209,961 patent/US20090075963A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2699632A1 (en) | 2009-03-19 |
PE20090680A1 (es) | 2009-06-19 |
CL2008002721A1 (es) | 2008-12-19 |
US20090075963A1 (en) | 2009-03-19 |
WO2009036355A1 (en) | 2009-03-19 |
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Legal Events
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