MX360738B - Parche transdérmico con quitosán y poloxámero. - Google Patents

Parche transdérmico con quitosán y poloxámero.

Info

Publication number
MX360738B
MX360738B MX2014007813A MX2014007813A MX360738B MX 360738 B MX360738 B MX 360738B MX 2014007813 A MX2014007813 A MX 2014007813A MX 2014007813 A MX2014007813 A MX 2014007813A MX 360738 B MX360738 B MX 360738B
Authority
MX
Mexico
Prior art keywords
poloxamer
chitosan
patch
bioadhesion
breaking strength
Prior art date
Application number
MX2014007813A
Other languages
English (en)
Other versions
MX2014007813A (es
Inventor
Juan Escobar Chávez José
Serrano Castañeda Pablo
Rodrigo Guadarrama Escobar Omar
Original Assignee
Univ Mexico Nac Autonoma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mexico Nac Autonoma filed Critical Univ Mexico Nac Autonoma
Priority to MX2014007813A priority Critical patent/MX360738B/es
Priority to PCT/MX2015/000091 priority patent/WO2015199526A1/es
Publication of MX2014007813A publication Critical patent/MX2014007813A/es
Publication of MX360738B publication Critical patent/MX360738B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención provee de un parche transdérmico con excelentes características fisicoquímicas tales como: resistencia a la ruptura, bioadhesión, bioadhesión-poshumectación, espesor, contenido químico y adecuada velocidad de disolución in vitro, que garantiza una adecuada liberación del activo para llevar a cabo su efecto terapéutico. el parche de la presente invención comprende una matriz polimérica con quitosán y un poloxámero, así como un principio activo y una microaguja, y tiene aplicación directamente en la piel del paciente humano y cumple con las propiedades de compatibilidad en la formulación, estabilidad química, no es irritante, no sensibiliza la piel, no provoca la acumulación de materia sebácea, no es fototóxico, inodoro, incoloro, tiene además buena resistencia a la ruptura y es bioadhesivo.
MX2014007813A 2014-06-25 2014-06-25 Parche transdérmico con quitosán y poloxámero. MX360738B (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MX2014007813A MX360738B (es) 2014-06-25 2014-06-25 Parche transdérmico con quitosán y poloxámero.
PCT/MX2015/000091 WO2015199526A1 (es) 2014-06-25 2015-06-10 Parche transdérmico con quitosán y poloxámero

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2014007813A MX360738B (es) 2014-06-25 2014-06-25 Parche transdérmico con quitosán y poloxámero.

Publications (2)

Publication Number Publication Date
MX2014007813A MX2014007813A (es) 2015-12-25
MX360738B true MX360738B (es) 2018-10-31

Family

ID=54938506

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007813A MX360738B (es) 2014-06-25 2014-06-25 Parche transdérmico con quitosán y poloxámero.

Country Status (2)

Country Link
MX (1) MX360738B (es)
WO (1) WO2015199526A1 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030312A1 (es) * 2000-08-03 2003-08-20 Antares Pharma Ipl Ag Composicion novedosa para la administracion transdermica y/o transmucosica de compuestos activos, que asegura adecuados niveles terapeuticos

Also Published As

Publication number Publication date
WO2015199526A1 (es) 2015-12-30
MX2014007813A (es) 2015-12-25

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Legal Events

Date Code Title Description
FG Grant or registration