JP2004505931A - 適切な治療水準を保証する活性化合物の経皮投与及び／又は経粘膜投与のための新規組成物 - Google Patents

適切な治療水準を保証する活性化合物の経皮投与及び／又は経粘膜投与のための新規組成物 Download PDF

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JP2004505931A
JP2004505931A JP2002517102A JP2002517102A JP2004505931A JP 2004505931 A JP2004505931 A JP 2004505931A JP 2002517102 A JP2002517102 A JP 2002517102A JP 2002517102 A JP2002517102 A JP 2002517102A JP 2004505931 A JP2004505931 A JP 2004505931A
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gel
pharmaceutical composition
active agent
transdermal
composition according
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JP2004505931A5 (enExample
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カッララ・ダリオ
ポルト・ガブリエル
ロドリゲズ・ジョルジェ
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アンタレス　ファルマ　アイピーエル　アクチェンゲゼルシャフト
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Publication of JP2004505931A publication Critical patent/JP2004505931A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002517102A 2000-08-03 2001-08-03 適切な治療水準を保証する活性化合物の経皮投与及び／又は経粘膜投与のための新規組成物 Pending JP2004505931A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP0007533 2000-08-03
PCT/EP2001/009007 WO2002011768A1 (en) 2000-08-03 2001-08-03 Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels

Publications (2)

Publication Number Publication Date
JP2004505931A true JP2004505931A (ja) 2004-02-26
JP2004505931A5 JP2004505931A5 (enExample) 2005-03-17

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JP2002517102A Pending JP2004505931A (ja) 2000-08-03 2001-08-03 適切な治療水準を保証する活性化合物の経皮投与及び／又は経粘膜投与のための新規組成物

Country Status (12)

Country Link
US (2) US7214381B2 (enExample)
EP (4) EP1323431B1 (enExample)
JP (1) JP2004505931A (enExample)
KR (1) KR100856523B1 (enExample)
AR (1) AR030312A1 (enExample)
AT (3) ATE356636T1 (enExample)
AU (2) AU2001282064B2 (enExample)
CA (1) CA2418135C (enExample)
DE (3) DE60127134T2 (enExample)
ES (2) ES2283425T3 (enExample)
NZ (1) NZ524423A (enExample)
WO (1) WO2002011768A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007533604A (ja) * 2003-08-08 2007-11-22 ミファルム ソシエタ ペル アチオニ ヒドロキシエチルセルロースに基づく生体接着性ゲル
JP2009512645A (ja) * 2005-10-21 2009-03-26 エルテーエス ローマン テラピー−ジステーメ アーゲー 親油性かつ／または低皮膚浸透性の活性物質を投与するための経皮治療システム
JP2011507904A (ja) * 2007-12-21 2011-03-10 ザーズ ファーマ， インコーポレイテッド アルプラゾラムおよび他の薬物を経皮送達するためのパッチ、製剤および関連する方法
JP2024012484A (ja) * 2017-09-27 2024-01-30 アクエスティブ セラピューティクス インコーポレイテッド 増強された透過を有する医薬組成物

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JP4855935B2 (ja) * 2003-08-08 2012-01-18 ミテック−イデア ソシエタ ア レスポンサビリタ リミタータ ヒドロキシエチルセルロースに基づく生体接着性ゲル
JP2009512645A (ja) * 2005-10-21 2009-03-26 エルテーエス ローマン テラピー−ジステーメ アーゲー 親油性かつ／または低皮膚浸透性の活性物質を投与するための経皮治療システム
JP2011507904A (ja) * 2007-12-21 2011-03-10 ザーズ ファーマ， インコーポレイテッド アルプラゾラムおよび他の薬物を経皮送達するためのパッチ、製剤および関連する方法
JP2024012484A (ja) * 2017-09-27 2024-01-30 アクエスティブ セラピューティクス インコーポレイテッド 増強された透過を有する医薬組成物

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