ES2249992B1 - Un procedimiento para fabricar compuestos enantiomericos del imidazol. - Google Patents

Un procedimiento para fabricar compuestos enantiomericos del imidazol. Download PDF

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Publication number
ES2249992B1
ES2249992B1 ES200402184A ES200402184A ES2249992B1 ES 2249992 B1 ES2249992 B1 ES 2249992B1 ES 200402184 A ES200402184 A ES 200402184A ES 200402184 A ES200402184 A ES 200402184A ES 2249992 B1 ES2249992 B1 ES 2249992B1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
chosen
maximum
sertaconazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200402184A
Other languages
English (en)
Spanish (es)
Other versions
ES2249992A1 (es
Inventor
Ines Petschen Olive
Francesc-Xavier Camps Camprubi
Juan Sallares Rosell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35614444&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2249992(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES200402184A priority Critical patent/ES2249992B1/es
Priority to PE2005001047A priority patent/PE20060720A1/es
Priority to PA20058645501A priority patent/PA8645501A1/es
Priority to ARP050103794A priority patent/AR050931A1/es
Priority to CA2577247A priority patent/CA2577247C/en
Priority to PT05799300T priority patent/PT1794152E/pt
Priority to UY29115A priority patent/UY29115A1/es
Priority to JP2007530669A priority patent/JP5048500B2/ja
Priority to MX2007002939A priority patent/MX2007002939A/es
Priority to DE602005008454T priority patent/DE602005008454D1/de
Priority to US11/662,255 priority patent/US7626038B2/en
Priority to DK05799300T priority patent/DK1794152T3/da
Priority to KR1020077005699A priority patent/KR100903922B1/ko
Priority to BRPI0515259-3A priority patent/BRPI0515259A/pt
Priority to PL05799300T priority patent/PL1794152T3/pl
Priority to RU2007113921/04A priority patent/RU2413728C2/ru
Priority to TW094131395A priority patent/TWI405760B/zh
Priority to AT05799300T priority patent/ATE402171T1/de
Priority to CN2005800306783A priority patent/CN101023077B/zh
Priority to HK07113516.1A priority patent/HK1105416B/en
Priority to PCT/EP2005/009824 priority patent/WO2006029811A1/en
Priority to EP05799300A priority patent/EP1794152B1/en
Priority to AU2005284330A priority patent/AU2005284330B2/en
Publication of ES2249992A1 publication Critical patent/ES2249992A1/es
Publication of ES2249992B1 publication Critical patent/ES2249992B1/es
Application granted granted Critical
Priority to NO20071817A priority patent/NO20071817L/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Catalysts (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ES200402184A 2004-09-13 2004-09-13 Un procedimiento para fabricar compuestos enantiomericos del imidazol. Expired - Fee Related ES2249992B1 (es)

Priority Applications (24)

Application Number Priority Date Filing Date Title
ES200402184A ES2249992B1 (es) 2004-09-13 2004-09-13 Un procedimiento para fabricar compuestos enantiomericos del imidazol.
PE2005001047A PE20060720A1 (es) 2004-09-13 2005-09-09 Procedimiento para fabricar r-(-)-sertaconazol mononitrato
PA20058645501A PA8645501A1 (es) 2004-09-13 2005-09-12 Un procedimiento para fabricar compuestos enantiomericos del imidazol
ARP050103794A AR050931A1 (es) 2004-09-13 2005-09-12 Un procedimiento para fabricar compuestos enantiomericos del imidazol que comprenden el r- sertaconazol y compuesto obtenido
KR1020077005699A KR100903922B1 (ko) 2004-09-13 2005-09-13 에난티오머 이미다졸 화합물 제조방법
AT05799300T ATE402171T1 (de) 2004-09-13 2005-09-13 Verfahren zur herstellung enantiomerer imidazolverbindungen
UY29115A UY29115A1 (es) 2004-09-13 2005-09-13 Un procedimiento para fabricar compuestos enantiomericos del imidazol
JP2007530669A JP5048500B2 (ja) 2004-09-13 2005-09-13 鏡像異性イミダゾール化合物の製造方法
MX2007002939A MX2007002939A (es) 2004-09-13 2005-09-13 Un procedimiento para fabricar compuestos enantiomeros del imidazol.
DE602005008454T DE602005008454D1 (de) 2004-09-13 2005-09-13 Verfahren zur herstellung enantiomerer imidazolverbindungen
US11/662,255 US7626038B2 (en) 2004-09-13 2005-09-13 Method for manufacturing enantiomeric imidazole compounds
DK05799300T DK1794152T3 (da) 2004-09-13 2005-09-13 Fremgangsmåde til fremstilling af enantiomeriske imidazol-forbindelser
CA2577247A CA2577247C (en) 2004-09-13 2005-09-13 Method for manufacturing enantiomeric imidazole compounds
BRPI0515259-3A BRPI0515259A (pt) 2004-09-13 2005-09-13 método para produção de compostos de imidazol enantioméricos
PL05799300T PL1794152T3 (pl) 2004-09-13 2005-09-13 Sposób wytwarzania enancjomerycznych związków imidazolowych
RU2007113921/04A RU2413728C2 (ru) 2004-09-13 2005-09-13 Способ получения r-(-)-сертаконазола мононитрата и полуацетонат r-(-)-сертаконазола мононитрата
TW094131395A TWI405760B (zh) 2004-09-13 2005-09-13 製造鏡像異構咪唑化合物之方法
PT05799300T PT1794152E (pt) 2004-09-13 2005-09-13 Método para a produção de compostos de imidazol enantioméricos
CN2005800306783A CN101023077B (zh) 2004-09-13 2005-09-13 生产对映体咪唑化合物的方法
HK07113516.1A HK1105416B (en) 2004-09-13 2005-09-13 Method for manufacturing enantiomeric imidazole compounds
PCT/EP2005/009824 WO2006029811A1 (en) 2004-09-13 2005-09-13 Method for manufacturing enantiomeric imidazole compounds
EP05799300A EP1794152B1 (en) 2004-09-13 2005-09-13 Method for manufacturing enantiomeric imidazole compounds
AU2005284330A AU2005284330B2 (en) 2004-09-13 2005-09-13 Method for manufacturing enantiomeric imidazole compounds
NO20071817A NO20071817L (no) 2004-09-13 2007-04-04 Fremgangsmate for a fremstille enantiomeriske imidazolforbindelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200402184A ES2249992B1 (es) 2004-09-13 2004-09-13 Un procedimiento para fabricar compuestos enantiomericos del imidazol.

Publications (2)

Publication Number Publication Date
ES2249992A1 ES2249992A1 (es) 2006-04-01
ES2249992B1 true ES2249992B1 (es) 2007-03-01

Family

ID=35614444

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200402184A Expired - Fee Related ES2249992B1 (es) 2004-09-13 2004-09-13 Un procedimiento para fabricar compuestos enantiomericos del imidazol.

Country Status (23)

Country Link
US (1) US7626038B2 (enExample)
EP (1) EP1794152B1 (enExample)
JP (1) JP5048500B2 (enExample)
KR (1) KR100903922B1 (enExample)
CN (1) CN101023077B (enExample)
AR (1) AR050931A1 (enExample)
AT (1) ATE402171T1 (enExample)
AU (1) AU2005284330B2 (enExample)
BR (1) BRPI0515259A (enExample)
CA (1) CA2577247C (enExample)
DE (1) DE602005008454D1 (enExample)
DK (1) DK1794152T3 (enExample)
ES (1) ES2249992B1 (enExample)
MX (1) MX2007002939A (enExample)
NO (1) NO20071817L (enExample)
PA (1) PA8645501A1 (enExample)
PE (1) PE20060720A1 (enExample)
PL (1) PL1794152T3 (enExample)
PT (1) PT1794152E (enExample)
RU (1) RU2413728C2 (enExample)
TW (1) TWI405760B (enExample)
UY (1) UY29115A1 (enExample)
WO (1) WO2006029811A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8635593B2 (en) * 2008-05-13 2014-01-21 Hewlett-Packard Development Company, L.P. Dynamic autocompletion tool
CN112595803A (zh) * 2020-12-31 2021-04-02 海南海神同洲制药有限公司 一种硝酸舍他康唑乳膏的鉴别方法
CN113480517B (zh) * 2021-07-30 2022-09-09 海南海神同洲制药有限公司 3-溴甲基-7-氯苯并[b]噻吩的合成方法
CN113501814A (zh) * 2021-07-30 2021-10-15 海南海神同洲制药有限公司 一种硝酸舍他康唑的纯化方法
CN113501815A (zh) * 2021-07-30 2021-10-15 海南海神同洲制药有限公司 一种硝酸舍他康唑晶型的制备方法
CN113816947A (zh) * 2021-08-25 2021-12-21 海南海神同洲制药有限公司 一种硝酸舍他康唑的重结晶方法
CN113735843B (zh) * 2021-09-07 2023-05-26 海南海神同洲制药有限公司 一种低熔点硝酸舍他康唑的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003068770A1 (en) * 2002-02-11 2003-08-21 Ferrer Internacional S.A. R- (-) -1- [2- (7-CHLOROBENZO [b] THIOPHEN-3 -YL- METHOXY) -2- (2,4-DICHLOROPHENYL) -ETHYL] -1H-IMIDAZOLE

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1096361B (it) 1978-05-18 1985-08-26 Recordati Chem Pharm Dibenzileteri sostituiti terapeuticamente attivi
JPS57169466A (en) * 1981-04-14 1982-10-19 Ota Seiyaku Kk Preparation of imidazole derivative
US5135943A (en) * 1984-02-02 1992-08-04 Ferrer Internacional S.A. 1H-imidazole derivative compounds and pharmaceutical compositions containing the same
ES8504779A1 (es) * 1984-02-02 1985-05-01 Ferrer Int Procedimiento de obtencion de nuevos derivados de 1h-imidazol
CA1250586A (en) 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
KR100336642B1 (ko) * 1995-01-04 2002-11-23 페레르 인터내쇼날 에스.에이. 1-[2,4-디클로로-β-[7-클로로벤조[B]티엔-3-일)메톡시]페네틸]이미다졸모노나이트레이트의폴리모르프B및C의제조방법
ATE375332T1 (de) * 1998-12-24 2007-10-15 Astellas Pharma Inc Imidazol verbindungen und ihre medizinische verwendung
CN1191250C (zh) * 2001-09-26 2005-03-02 河北省药物研究所 一种硝酸舍他康唑的合成方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003068770A1 (en) * 2002-02-11 2003-08-21 Ferrer Internacional S.A. R- (-) -1- [2- (7-CHLOROBENZO [b] THIOPHEN-3 -YL- METHOXY) -2- (2,4-DICHLOROPHENYL) -ETHYL] -1H-IMIDAZOLE

Also Published As

Publication number Publication date
MX2007002939A (es) 2007-04-27
US20080108682A1 (en) 2008-05-08
AR050931A1 (es) 2006-12-06
PA8645501A1 (es) 2006-05-16
EP1794152A1 (en) 2007-06-13
KR100903922B1 (ko) 2009-06-19
UY29115A1 (es) 2005-11-30
RU2007113921A (ru) 2008-10-20
CN101023077B (zh) 2012-05-23
JP2008512421A (ja) 2008-04-24
TW200621756A (en) 2006-07-01
ATE402171T1 (de) 2008-08-15
JP5048500B2 (ja) 2012-10-17
US7626038B2 (en) 2009-12-01
RU2413728C2 (ru) 2011-03-10
PL1794152T3 (pl) 2008-12-31
CN101023077A (zh) 2007-08-22
DE602005008454D1 (de) 2008-09-04
CA2577247A1 (en) 2006-03-23
EP1794152B1 (en) 2008-07-23
HK1105416A1 (en) 2008-02-15
NO20071817L (no) 2007-05-16
KR20070042206A (ko) 2007-04-20
PT1794152E (pt) 2008-10-24
WO2006029811A1 (en) 2006-03-23
PE20060720A1 (es) 2006-07-11
AU2005284330A1 (en) 2006-03-23
TWI405760B (zh) 2013-08-21
CA2577247C (en) 2011-07-05
ES2249992A1 (es) 2006-04-01
BRPI0515259A (pt) 2008-07-15
AU2005284330B2 (en) 2011-01-06
DK1794152T3 (da) 2008-11-17

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