ES2168121T3 - Derivados de acido 3-amino-2-mercaptobenzoico y procedimientos para su preparacion. - Google Patents
Derivados de acido 3-amino-2-mercaptobenzoico y procedimientos para su preparacion.Info
- Publication number
- ES2168121T3 ES2168121T3 ES96810865T ES96810865T ES2168121T3 ES 2168121 T3 ES2168121 T3 ES 2168121T3 ES 96810865 T ES96810865 T ES 96810865T ES 96810865 T ES96810865 T ES 96810865T ES 2168121 T3 ES2168121 T3 ES 2168121T3
- Authority
- ES
- Spain
- Prior art keywords
- sub
- replaced
- compounds
- substituted
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 3
- 239000004215 Carbon black (E152) Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 229930195733 hydrocarbon Natural products 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- DZRJLJPPUJADOO-UHFFFAOYSA-N chaetomin Natural products CN1C(=O)C2(Cc3cn(C)c4ccccc34)SSC1(CO)C(=O)N2C56CC78SSC(CO)(N(C)C7=O)C(=O)N8C5Nc9ccccc69 DZRJLJPPUJADOO-UHFFFAOYSA-N 0.000 abstract 1
- 150000002019 disulfides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 230000003641 microbiacidal effect Effects 0.000 abstract 1
- 229940124561 microbicide Drugs 0.000 abstract 1
- 239000002855 microbicide agent Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen(.) Chemical compound [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
- C07C319/12—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by reactions not involving the formation of mercapto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/26—Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/22—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
Abstract
LOS COMPUESTOS DE FORMULA I Y SUS DERIVADOS DISULFURO Y SALES, SON PRODUCTOS INTERMEDIARIOS IMPORTANTES PARA LA PREPARACION DE COMPUESTOS QUE PRESENTAN UNA ACCION INMUNIZADORA DE PLANTAS Y MICROBICIDA, TENIENDO DICHOS COMPUESTOS LA FORMULA III EN LOS COMPUESTOS DE FORMULAS I Y III, X ES HALOGENO, N EN 0,1,2 O 3 Z ES CN, CO-A O CS-A A ES HIDROGENO, HALOGENO, OR{SUB,1}, SR{SUB,2} Y N(R{SUB,3})R{SUB,4}; R{SUB,1} A R{SUB,4} SON HIDROGENO, UN RADICAL HIDROCARBONADO QUE CONTIENE NO MAS DE 8 ATOMOS DE CARBONO, INSATURADO O SATURADO, DE CADENA ABIERTA, SUSTITUIDO O SIN SUSTITUIR, UN RADICAL HIDROCARBONADO QUE CONTIENE NO MAS DE 10 ATOMOS DE CARBONO, SATURADO O INSATURADO, SUSTITUIDO O CICLICO NO SUSTITUIDO, FENETILO O BENCILO SUSTITUIDO O SIN SUSTITUIR, UN GRUPO ALCANOILO SUSTITUIDO O SIN SUSTITUIR, QUE CONTIENE NO MAS DE 8 ATOMOS DE CARBONO, UN GRUPO BENZOILO SUSTITUIDO O SIN SUSTITUIR, O UN RADICAL HETEROCICLILO SUSTITUIDO O SIN SUSTITUIR; O R{SUB,3} Y R{SUB,4}, JUNTO CON EL ATOMO DE NITROGENO ALCUAL ESTAN UNIDOS, FORMAN UN RADICAL HETEROCICLICO SUSTITUIDO O SIN SUSTITUIR, DE 5 O 6 MIEMBROS, QUE TIENE 1-3 HETEROATOMOS O, S Y/O N. SE DESCRIBEN ASIMISMO PROCEDIMIENTOS PARA LA PREPARACION DE COMPUESTOS DE FORMULA I.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH363795 | 1995-12-21 | ||
CH363795 | 1995-12-21 | ||
US08/770,353 US5770758A (en) | 1995-12-21 | 1996-12-20 | 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2168121T3 true ES2168121T3 (es) | 2002-06-01 |
ES2168121T7 ES2168121T7 (es) | 2013-09-24 |
Family
ID=25693502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96810865T Active ES2168121T7 (es) | 1995-12-21 | 1996-12-12 | Derivados de ácido 3-amino-2-mercaptobenzoico y procedimientos para su preparación |
Country Status (21)
Country | Link |
---|---|
US (1) | US5770758A (es) |
EP (1) | EP0780372B3 (es) |
JP (1) | JP4217924B2 (es) |
KR (1) | KR100470887B1 (es) |
CN (2) | CN1078888C (es) |
AT (1) | ATE208760T1 (es) |
AU (1) | AU713526B2 (es) |
BR (1) | BR9606092A (es) |
CA (1) | CA2193460C (es) |
CZ (1) | CZ291857B6 (es) |
DE (1) | DE69616956T3 (es) |
DK (1) | DK0780372T3 (es) |
ES (1) | ES2168121T7 (es) |
HU (1) | HU221600B (es) |
IL (3) | IL133900A (es) |
MX (2) | MXPA02000515A (es) |
PL (1) | PL187885B1 (es) |
PT (1) | PT780372E (es) |
RU (1) | RU2176241C2 (es) |
SK (1) | SK283840B6 (es) |
ZA (1) | ZA9610774B (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6002013A (en) * | 1995-12-21 | 1999-12-14 | Novartis Corporation | 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation |
GB9724586D0 (en) * | 1997-11-20 | 1998-01-21 | Rhone Poulenc Agriculture | New herbicides |
KR101129933B1 (ko) | 2002-09-25 | 2012-03-23 | 메모리 파마슈티칼스 코포레이션 | 인다졸, 벤조티아졸 및 벤조이소티아졸 및 그의 제조 및용도 |
DE10313887A1 (de) * | 2003-03-27 | 2004-10-28 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zum selektiven Gewinnen von Gold aus goldhaltigen Materialien |
CN104383542B (zh) | 2003-04-08 | 2017-09-26 | 普罗热尼奇制药公司 | 包含甲基纳曲酮的药物配方 |
JP2007523868A (ja) * | 2003-07-10 | 2007-08-23 | アキリオン ファーマシューティカルズ,インコーポレーテッド | ウイルス複製の阻害薬として有用な置換アリールチオウレア誘導体類 |
JP4995075B2 (ja) | 2004-03-25 | 2012-08-08 | メモリー・ファーマシューティカルズ・コーポレイション | インダゾール、ベンゾチアゾール、ベンゾイソチアゾール、ベンズイソキサゾール、ならびにそれらの調製および使用 |
AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
US7888378B2 (en) * | 2006-03-02 | 2011-02-15 | Mallinckrodt Inc. | Thiadiazole compounds and uses thereof |
MX2009010552A (es) | 2007-03-29 | 2009-12-14 | Progenics Pharm Inc | Antagonistas de receptor de opioide periferico y usos de los mismos. |
MX2009010515A (es) | 2007-03-29 | 2009-10-19 | Wyeth Corp | Antagonistas del receptor opioide periferico y usos de los mismos. |
AU2008233133B2 (en) | 2007-03-29 | 2014-03-27 | Progenics Pharmaceuticals, Inc. | Crystal forms of (R) -N-methylnaltrexone bromide and uses thereof |
KR101581480B1 (ko) | 2008-02-06 | 2015-12-30 | 프로제닉스 파머슈티컬스, 인코포레이티드 | (r),(r)-2,2'-비스-메틸날트렉손의 제조법 및 용도 |
CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
CN101492429B (zh) * | 2008-12-10 | 2010-12-15 | 上海泰禾(集团)有限公司 | 一种苯并-[1,2,3]-噻二唑-7-甲酸三氟乙酯的提纯方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4150140A (en) * | 1976-12-23 | 1979-04-17 | The Upjohn Company | Benzothiazolyl oxanic acids, esters and salts |
DE2757924A1 (de) * | 1977-12-24 | 1979-07-05 | Hoechst Ag | Verfahren zur herstellung von vinylchlorid-polymerisaten |
DE3601286A1 (de) * | 1986-01-17 | 1987-07-23 | Consiglio Nazionale Ricerche | Sammelmittel fuer die selektive flotation von blei- und zinkerzen und verfahren zu deren herstellung |
ATE82668T1 (de) * | 1987-08-21 | 1992-12-15 | Ciba Geigy Ag | Benzothiadiazole und ihre verwendung in verfahren und mitteln gegen pflanzenkrankheiten. |
ATE95815T1 (de) * | 1989-02-21 | 1993-10-15 | Ciba Geigy Ag | Mittel zum schutz von pflanzen gegen krankheiten. |
DE59207481D1 (de) | 1991-08-30 | 1996-12-12 | Hoechst Ag | Verfahren zur Herstellung von 2-Aminobenzthiazolen |
JPH0690518A (ja) * | 1992-09-09 | 1994-03-29 | Toshiba Corp | 地絡継電器 |
JP3310104B2 (ja) * | 1994-04-04 | 2002-07-29 | 三新化学工業株式会社 | 2−アミノチオフェノール類の製造方法 |
US5883283A (en) * | 1994-10-17 | 1999-03-16 | Novartis Finance Corporation | Process for the preparation of substituted 3-aminobenzonitriles |
-
1996
- 1996-12-12 DK DK96810865T patent/DK0780372T3/da active
- 1996-12-12 ES ES96810865T patent/ES2168121T7/es active Active
- 1996-12-12 EP EP96810865.4A patent/EP0780372B3/en not_active Expired - Lifetime
- 1996-12-12 IL IL13390096A patent/IL133900A/en not_active IP Right Cessation
- 1996-12-12 PT PT96810865T patent/PT780372E/pt unknown
- 1996-12-12 DE DE69616956.8T patent/DE69616956T3/de not_active Expired - Lifetime
- 1996-12-12 AT AT96810865T patent/ATE208760T1/de active
- 1996-12-12 IL IL11981996A patent/IL119819A/en not_active IP Right Cessation
- 1996-12-19 PL PL96317601A patent/PL187885B1/pl unknown
- 1996-12-19 CA CA002193460A patent/CA2193460C/en not_active Expired - Fee Related
- 1996-12-19 BR BR9606092A patent/BR9606092A/pt active IP Right Grant
- 1996-12-19 CZ CZ19963773A patent/CZ291857B6/cs not_active IP Right Cessation
- 1996-12-19 MX MXPA02000515A patent/MXPA02000515A/es active IP Right Grant
- 1996-12-19 MX MX9606665A patent/MX9606665A/es unknown
- 1996-12-19 HU HU9603527A patent/HU221600B/hu not_active IP Right Cessation
- 1996-12-19 SK SK1636-96A patent/SK283840B6/sk not_active IP Right Cessation
- 1996-12-20 CN CN96117901A patent/CN1078888C/zh not_active Expired - Lifetime
- 1996-12-20 RU RU96124374/04A patent/RU2176241C2/ru not_active IP Right Cessation
- 1996-12-20 CN CNB001316702A patent/CN1163491C/zh not_active Expired - Lifetime
- 1996-12-20 US US08/770,353 patent/US5770758A/en not_active Expired - Lifetime
- 1996-12-20 ZA ZA9610774A patent/ZA9610774B/xx unknown
- 1996-12-20 AU AU76404/96A patent/AU713526B2/en not_active Ceased
- 1996-12-20 JP JP35519496A patent/JP4217924B2/ja not_active Expired - Lifetime
-
2000
- 2000-01-06 IL IL13390000A patent/IL133900A0/xx active IP Right Grant
-
2004
- 2004-06-30 KR KR1020040050522A patent/KR100470887B1/ko not_active IP Right Cessation
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Legal Events
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FG2A | Definitive protection |
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