DE69616956T2 - 3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung - Google Patents

3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung

Info

Publication number
DE69616956T2
DE69616956T2 DE69616956T DE69616956T DE69616956T2 DE 69616956 T2 DE69616956 T2 DE 69616956T2 DE 69616956 T DE69616956 T DE 69616956T DE 69616956 T DE69616956 T DE 69616956T DE 69616956 T2 DE69616956 T2 DE 69616956T2
Authority
DE
Germany
Prior art keywords
substituted
unsubstituted
compounds
preparation
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69616956T
Other languages
English (en)
Other versions
DE69616956T3 (de
DE69616956D1 (de
Inventor
Walter Kunz
Beat Jau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
Original Assignee
Syngenta Participations AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations AG filed Critical Syngenta Participations AG
Application granted granted Critical
Publication of DE69616956D1 publication Critical patent/DE69616956D1/de
Publication of DE69616956T2 publication Critical patent/DE69616956T2/de
Publication of DE69616956T3 publication Critical patent/DE69616956T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/12—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by reactions not involving the formation of mercapto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/26—Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/22—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE69616956.8T 1995-12-21 1996-12-12 3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung Expired - Lifetime DE69616956T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH363795 1995-12-21
CH363795 1995-12-21
EP96810865.4A EP0780372B3 (de) 1995-12-21 1996-12-12 3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung
US08/770,353 US5770758A (en) 1995-12-21 1996-12-20 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation

Publications (3)

Publication Number Publication Date
DE69616956D1 DE69616956D1 (de) 2001-12-20
DE69616956T2 true DE69616956T2 (de) 2002-06-20
DE69616956T3 DE69616956T3 (de) 2014-01-30

Family

ID=25693502

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69616956.8T Expired - Lifetime DE69616956T3 (de) 1995-12-21 1996-12-12 3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung

Country Status (21)

Country Link
US (1) US5770758A (de)
EP (1) EP0780372B3 (de)
JP (1) JP4217924B2 (de)
KR (1) KR100470887B1 (de)
CN (2) CN1078888C (de)
AT (1) ATE208760T1 (de)
AU (1) AU713526B2 (de)
BR (1) BR9606092A (de)
CA (1) CA2193460C (de)
CZ (1) CZ291857B6 (de)
DE (1) DE69616956T3 (de)
DK (1) DK0780372T3 (de)
ES (1) ES2168121T7 (de)
HU (1) HU221600B (de)
IL (3) IL133900A (de)
MX (2) MXPA02000515A (de)
PL (1) PL187885B1 (de)
PT (1) PT780372E (de)
RU (1) RU2176241C2 (de)
SK (1) SK283840B6 (de)
ZA (1) ZA9610774B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10313887A1 (de) * 2003-03-27 2004-10-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum selektiven Gewinnen von Gold aus goldhaltigen Materialien

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002013A (en) * 1995-12-21 1999-12-14 Novartis Corporation 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation
GB9724586D0 (en) * 1997-11-20 1998-01-21 Rhone Poulenc Agriculture New herbicides
PL210065B1 (pl) 2002-09-25 2011-11-30 Memory Pharm Corp Związki indazole, benzotiazole i benzoizotiazole, kompozycje farmaceutyczne je zawierające oraz zastosowanie związków
PT1615646E (pt) 2003-04-08 2015-02-12 Progenics Pharm Inc Formulações farmacêuticas com metilnaltrexona
OA13187A (en) * 2003-07-10 2006-12-13 Achillion Pharmaceuticals Inc Substituted arylthiourea derivatives useful as inhibitors of viral replication.
KR101176670B1 (ko) 2004-03-25 2012-08-23 메모리 파마슈티칼스 코포레이션 인다졸, 벤조티아졸, 벤조이소티아졸, 벤즈이속사졸, 및그의 제조법 및 용도
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
US7888378B2 (en) 2006-03-02 2011-02-15 Mallinckrodt Inc. Thiadiazole compounds and uses thereof
MX351611B (es) 2007-03-29 2017-10-20 Wyeth Llc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
ES2570374T3 (es) 2007-03-29 2016-05-18 Progenics Pharm Inc Antagonistas del receptor opioide periférico y usos de los mismos
PT2139890E (pt) 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
WO2009099411A1 (en) 2008-02-06 2009-08-13 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
CN101492429B (zh) * 2008-12-10 2010-12-15 上海泰禾(集团)有限公司 一种苯并-[1，2，3]-噻二唑-7-甲酸三氟乙酯的提纯方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150140A (en) * 1976-12-23 1979-04-17 The Upjohn Company Benzothiazolyl oxanic acids, esters and salts
DE2757924A1 (de) * 1977-12-24 1979-07-05 Hoechst Ag Verfahren zur herstellung von vinylchlorid-polymerisaten
DE3601286A1 (de) * 1986-01-17 1987-07-23 Consiglio Nazionale Ricerche Sammelmittel fuer die selektive flotation von blei- und zinkerzen und verfahren zu deren herstellung
EP0313512B1 (de) * 1987-08-21 1992-11-25 Ciba-Geigy Ag Benzothiadiazole und ihre Verwendung in Verfahren und Mitteln gegen Pflanzenkrankheiten
ES2060120T3 (es) * 1989-02-21 1994-11-16 Ciba Geigy Ag Agente para proteger las plantas de enfermedades.
DE59207481D1 (de) 1991-08-30 1996-12-12 Hoechst Ag Verfahren zur Herstellung von 2-Aminobenzthiazolen
JPH0690518A (ja) * 1992-09-09 1994-03-29 Toshiba Corp 地絡継電器
JP3310104B2 (ja) * 1994-04-04 2002-07-29 三新化学工業株式会社 ２−アミノチオフェノール類の製造方法
SK47397A3 (en) * 1994-10-17 1997-11-05 Ciba Geigy Ag Preparation method of substituted 3-aminobenzonitriles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10313887A1 (de) * 2003-03-27 2004-10-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum selektiven Gewinnen von Gold aus goldhaltigen Materialien

Also Published As

Publication number Publication date
IL133900A0 (en) 2001-04-30
ZA9610774B (en) 1997-06-30
ATE208760T1 (de) 2001-11-15
CN1163491C (zh) 2004-08-25
HUP9603527A2 (en) 1997-09-29
IL119819A (en) 2004-07-25
DK0780372T3 (da) 2002-03-11
CA2193460C (en) 2007-03-27
CN1156722A (zh) 1997-08-13
JPH09235279A (ja) 1997-09-09
EP0780372B1 (de) 2001-11-14
PL187885B1 (pl) 2004-10-29
ES2168121T3 (es) 2002-06-01
CN1392144A (zh) 2003-01-22
AU713526C (en) 1997-06-26
DE69616956T3 (de) 2014-01-30
IL119819A0 (en) 1997-03-18
HU221600B (hu) 2002-11-28
EP0780372A3 (de) 1997-09-17
SK283840B6 (sk) 2004-03-02
CA2193460A1 (en) 1997-06-22
HU9603527D0 (en) 1997-02-28
US5770758A (en) 1998-06-23
JP4217924B2 (ja) 2009-02-04
KR100470887B1 (ko) 2005-03-14
AU7640496A (en) 1997-06-26
CN1078888C (zh) 2002-02-06
SK163696A3 (en) 1997-10-08
PL317601A1 (en) 1997-06-23
HUP9603527A3 (en) 1999-04-28
CZ291857B6 (cs) 2003-06-18
IL133900A (en) 2004-07-25
MX9606665A (es) 1997-06-28
EP0780372A2 (de) 1997-06-25
EP0780372B3 (de) 2013-05-22
MXPA02000515A (es) 2002-09-17
CZ377396A3 (en) 1997-07-16
RU2176241C2 (ru) 2001-11-27
AU713526B2 (en) 1999-12-02
DE69616956D1 (de) 2001-12-20
ES2168121T7 (es) 2013-09-24
PT780372E (pt) 2002-04-29
BR9606092A (pt) 1998-09-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC