DE3886185D1 - 2-Thiazolidinon-Derivate und diese enthaltende pharmazeutische Präparate, Verfahren zu deren Herstellung und deren Verwendung. - Google Patents
2-Thiazolidinon-Derivate und diese enthaltende pharmazeutische Präparate, Verfahren zu deren Herstellung und deren Verwendung.Info
- Publication number
- DE3886185D1 DE3886185D1 DE88120908T DE3886185T DE3886185D1 DE 3886185 D1 DE3886185 D1 DE 3886185D1 DE 88120908 T DE88120908 T DE 88120908T DE 3886185 T DE3886185 T DE 3886185T DE 3886185 D1 DE3886185 D1 DE 3886185D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- pharmaceutical preparations
- preparations containing
- thiazolidinone derivatives
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- SLYRGJDSFOCAAI-UHFFFAOYSA-N 1,3-thiazolidin-2-one Chemical class O=C1NCCS1 SLYRGJDSFOCAAI-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 230000001120 cytoprotective effect Effects 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 230000027119 gastric acid secretion Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU875632A HU198915B (en) | 1987-12-14 | 1987-12-14 | Process for producing new 2-thiazolidinone derivatives and pharmaceutical compositions containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3886185D1 true DE3886185D1 (de) | 1994-01-20 |
DE3886185T2 DE3886185T2 (de) | 1994-05-05 |
Family
ID=10970509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE88120908T Expired - Fee Related DE3886185T2 (de) | 1987-12-14 | 1988-12-14 | 2-Thiazolidinon-Derivate und diese enthaltende pharmazeutische Präparate, Verfahren zu deren Herstellung und deren Verwendung. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4937252A (de) |
EP (1) | EP0320910B1 (de) |
JP (1) | JPH02279A (de) |
KR (1) | KR920010179B1 (de) |
CN (1) | CN1019196B (de) |
AT (1) | ATE98235T1 (de) |
CA (1) | CA1332419C (de) |
DE (1) | DE3886185T2 (de) |
ES (1) | ES2049243T3 (de) |
HU (1) | HU198915B (de) |
LT (1) | LT2199B (de) |
LV (1) | LV5491A3 (de) |
SU (1) | SU1657062A3 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU205092B (en) * | 1989-11-24 | 1992-03-30 | Richter Gedeon Vegyeszet | Process for producing new thiazolidinone derivatives and pharmaceutical compositions comprising same |
HU210789B (en) * | 1992-12-23 | 1995-07-28 | Richter Gedeon Vegyeszet | Process for preparing new thiazolidinone derivatives and pharmaceutical preparations containing them |
CN103351358B (zh) * | 2013-07-03 | 2015-05-27 | 北京化工大学 | 一种5-取代2-噻唑烷酮的制备方法 |
RU2643669C1 (ru) * | 2017-04-03 | 2018-02-05 | Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) | 3-[3-(морфолин-4-ил)пропил]-2-[(2,2,3-триметилциклопент-3-ен-1-ил)метил]-1,3-тиазолидин-4-он, обладающий противоязвенной и противовоспалительной активностью |
CN115093378B (zh) * | 2022-07-21 | 2024-01-26 | 三门峡奥科科技有限公司 | 一种2-噻唑烷酮的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3066919A (en) * | 1958-11-12 | 1962-12-04 | Waimer Eberhard | Concrete mixer |
JPS53127466A (en) * | 1977-04-13 | 1978-11-07 | Asahi Chem Ind Co Ltd | Thiocarbamate type heterocyclic compounds and its preparation |
US4664694A (en) * | 1985-04-24 | 1987-05-12 | Uniroyal Chemical Company, Inc. | Substituted thiazolidinones useful as plant growth regulators |
-
1987
- 1987-12-14 HU HU875632A patent/HU198915B/hu not_active IP Right Cessation
-
1988
- 1988-12-07 CA CA000585257A patent/CA1332419C/en not_active Expired - Fee Related
- 1988-12-13 JP JP63314813A patent/JPH02279A/ja active Pending
- 1988-12-13 CN CN88108626A patent/CN1019196B/zh not_active Expired
- 1988-12-13 US US07/283,809 patent/US4937252A/en not_active Expired - Fee Related
- 1988-12-14 DE DE88120908T patent/DE3886185T2/de not_active Expired - Fee Related
- 1988-12-14 ES ES88120908T patent/ES2049243T3/es not_active Expired - Lifetime
- 1988-12-14 SU SU884613151A patent/SU1657062A3/ru active
- 1988-12-14 AT AT88120908T patent/ATE98235T1/de not_active IP Right Cessation
- 1988-12-14 KR KR1019880016674A patent/KR920010179B1/ko not_active IP Right Cessation
- 1988-12-14 EP EP88120908A patent/EP0320910B1/de not_active Expired - Lifetime
-
1993
- 1993-06-28 LV LV930678A patent/LV5491A3/xx unknown
- 1993-08-13 LT LTRP854A patent/LT2199B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CN1019196B (zh) | 1992-11-25 |
CN1033625A (zh) | 1989-07-05 |
EP0320910A1 (de) | 1989-06-21 |
KR920010179B1 (ko) | 1992-11-19 |
ATE98235T1 (de) | 1993-12-15 |
ES2049243T3 (es) | 1994-04-16 |
KR890009897A (ko) | 1989-08-04 |
EP0320910B1 (de) | 1993-12-08 |
SU1657062A3 (ru) | 1991-06-15 |
DE3886185T2 (de) | 1994-05-05 |
LV5491A3 (lv) | 1994-03-10 |
HU198915B (en) | 1989-12-28 |
LT2199B (lt) | 1993-10-15 |
HUT49125A (en) | 1989-08-28 |
JPH02279A (ja) | 1990-01-05 |
US4937252A (en) | 1990-06-26 |
CA1332419C (en) | 1994-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |