ES2049243T3 - Procedimiento para la preparacion y utilizacion de nuevos derivados de 2-tiozolidinona y composiciones farmaceuticas que los contienen. - Google Patents

Procedimiento para la preparacion y utilizacion de nuevos derivados de 2-tiozolidinona y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2049243T3
ES2049243T3 ES88120908T ES88120908T ES2049243T3 ES 2049243 T3 ES2049243 T3 ES 2049243T3 ES 88120908 T ES88120908 T ES 88120908T ES 88120908 T ES88120908 T ES 88120908T ES 2049243 T3 ES2049243 T3 ES 2049243T3
Authority
ES
Spain
Prior art keywords
new
thiozolidinone
derivatives
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88120908T
Other languages
English (en)
Inventor
Istvan Szabadkai
Kalman Dr Dipl-Chem Harsanyi
Agnes Lampert
Gyorgy Dr Dipl-Chem Domany
Bela Dr Dipl-Chem Hegedus
Pap Marta Kapolnasne
Elemer Ezer
Judit Dr Matuz
Katalin Dr Saghy
Laszlo Dr Szporny
Gyorgy Dr Hajos
Krisztina Szekely
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Application granted granted Critical
Publication of ES2049243T3 publication Critical patent/ES2049243T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)

Abstract

LA PRESENTE INVENCION RELATA UNA TIAZOLIDINONA - 2 NUEVA DERIVADA DE LA FORMULA GENERAL (I), DONDE UNA POSICION DE HIDROGENO, HALOGENO O UN ALQUIL C1 - C4, ALCOXI C1 - C4 O GRUPO NITRO, Y N ES 0 O 1. LOS COMPONENTES ACORDADOS EN LA INVENCION MUESTRAN UN CITOPROTECTIVO Y ACIDO GASTRICO DE EFECTO SECRECCION INHIBIDA Y ADEMAS PUEDE SER USADO EN LA TERAPIA DE GASTRITIS Y ULCERA DEL DUODENO. LA INVENCION INCLUYE METODOS DE PREPARACION DE LOS COMPUESTOS ANTERIORES CON LA FORMULA GENERAL (I) Y COMPOSICION FARMACEUTICA QUE LOS CONTIENE.
ES88120908T 1987-12-14 1988-12-14 Procedimiento para la preparacion y utilizacion de nuevos derivados de 2-tiozolidinona y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2049243T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU875632A HU198915B (en) 1987-12-14 1987-12-14 Process for producing new 2-thiazolidinone derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ES2049243T3 true ES2049243T3 (es) 1994-04-16

Family

ID=10970509

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88120908T Expired - Lifetime ES2049243T3 (es) 1987-12-14 1988-12-14 Procedimiento para la preparacion y utilizacion de nuevos derivados de 2-tiozolidinona y composiciones farmaceuticas que los contienen.

Country Status (13)

Country Link
US (1) US4937252A (es)
EP (1) EP0320910B1 (es)
JP (1) JPH02279A (es)
KR (1) KR920010179B1 (es)
CN (1) CN1019196B (es)
AT (1) ATE98235T1 (es)
CA (1) CA1332419C (es)
DE (1) DE3886185T2 (es)
ES (1) ES2049243T3 (es)
HU (1) HU198915B (es)
LT (1) LT2199B (es)
LV (1) LV5491A3 (es)
SU (1) SU1657062A3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU205092B (en) * 1989-11-24 1992-03-30 Richter Gedeon Vegyeszet Process for producing new thiazolidinone derivatives and pharmaceutical compositions comprising same
HU210789B (en) * 1992-12-23 1995-07-28 Richter Gedeon Vegyeszet Process for preparing new thiazolidinone derivatives and pharmaceutical preparations containing them
CN103351358B (zh) * 2013-07-03 2015-05-27 北京化工大学 一种5-取代2-噻唑烷酮的制备方法
RU2643669C1 (ru) * 2017-04-03 2018-02-05 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) 3-[3-(морфолин-4-ил)пропил]-2-[(2,2,3-триметилциклопент-3-ен-1-ил)метил]-1,3-тиазолидин-4-он, обладающий противоязвенной и противовоспалительной активностью
CN115093378B (zh) * 2022-07-21 2024-01-26 三门峡奥科科技有限公司 一种2-噻唑烷酮的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3066919A (en) * 1958-11-12 1962-12-04 Waimer Eberhard Concrete mixer
JPS53127466A (en) * 1977-04-13 1978-11-07 Asahi Chem Ind Co Ltd Thiocarbamate type heterocyclic compounds and its preparation
US4664694A (en) * 1985-04-24 1987-05-12 Uniroyal Chemical Company, Inc. Substituted thiazolidinones useful as plant growth regulators

Also Published As

Publication number Publication date
EP0320910A1 (en) 1989-06-21
JPH02279A (ja) 1990-01-05
CN1033625A (zh) 1989-07-05
DE3886185D1 (de) 1994-01-20
HU198915B (en) 1989-12-28
DE3886185T2 (de) 1994-05-05
US4937252A (en) 1990-06-26
ATE98235T1 (de) 1993-12-15
EP0320910B1 (en) 1993-12-08
SU1657062A3 (ru) 1991-06-15
KR890009897A (ko) 1989-08-04
HUT49125A (en) 1989-08-28
KR920010179B1 (ko) 1992-11-19
LV5491A3 (lv) 1994-03-10
CN1019196B (zh) 1992-11-25
CA1332419C (en) 1994-10-11
LT2199B (lt) 1993-10-15

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