ATE124953T1 - Gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus. - Google Patents

Gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus.

Info

Publication number
ATE124953T1
ATE124953T1 AT90106972T AT90106972T ATE124953T1 AT E124953 T1 ATE124953 T1 AT E124953T1 AT 90106972 T AT90106972 T AT 90106972T AT 90106972 T AT90106972 T AT 90106972T AT E124953 T1 ATE124953 T1 AT E124953T1
Authority
AT
Austria
Prior art keywords
bale
production
pharmaceutical compositions
acid derivatives
compounds
Prior art date
Application number
AT90106972T
Other languages
English (en)
Inventor
Roberto Pellicciari
Aldo Roda
Giuliano Frigerio
Original Assignee
Giuliani Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuliani Spa filed Critical Giuliani Spa
Application granted granted Critical
Publication of ATE124953T1 publication Critical patent/ATE124953T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90106972T 1989-04-17 1990-04-11 Gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus. ATE124953T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920169A IT1229569B (it) 1989-04-17 1989-04-17 Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.

Publications (1)

Publication Number Publication Date
ATE124953T1 true ATE124953T1 (de) 1995-07-15

Family

ID=11164375

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90106972T ATE124953T1 (de) 1989-04-17 1990-04-11 Gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus.

Country Status (10)

Country Link
US (1) US5057509A (de)
EP (1) EP0393494B1 (de)
JP (1) JP2816589B2 (de)
AT (1) ATE124953T1 (de)
CA (1) CA2014544C (de)
DE (1) DE69020781T2 (de)
DK (1) DK0393494T3 (de)
ES (1) ES2074492T3 (de)
GR (1) GR3017640T3 (de)
IT (1) IT1229569B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166374A (en) * 1989-04-17 1992-11-24 Giuliani S.P.A. Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
CA2157594A1 (en) * 1993-03-10 1994-09-15 Leah L. Frye Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5840740A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds and a method of treating infection using the aminosterol compounds
US5856535A (en) * 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
US5994336A (en) * 1995-06-07 1999-11-30 Magainin Pharmaceuticals Inc. Method of inhibiting proliferation of cells by administering an aminosterol compound
US5792635A (en) * 1995-06-07 1998-08-11 Magainin Pharmaceuticals, Inc. Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
US5840936A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
US5874597A (en) * 1995-06-07 1999-02-23 Magainin Pharmaceuticals, Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5763430A (en) * 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound
US5795885A (en) * 1995-06-07 1998-08-18 Magainin Pharmaceuticals Inc. Method of inhibiting profileration of cells by administering an aminosterol compound
US6143738A (en) * 1995-06-07 2000-11-07 Magainin Pharmaceuticals, Inc. Therapeutic uses for an aminosterol compound
US5847172A (en) * 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US6596712B2 (en) 1996-04-26 2003-07-22 Genaera Corporation Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
JP2000510460A (ja) * 1996-04-26 2000-08-15 マゲイニン・ファーマシューティカルズ・インコーポレーテッド スクアラミンを他の抗癌剤と併用する上皮性悪性腫瘍の治療
US6262283B1 (en) 1996-12-06 2001-07-17 Magainin Pharmaceuticals Inc. Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
CA2406847C (en) * 2000-04-12 2009-11-17 Genaera Corporation Regioselective and stereoselective oxidation of fused ring systems useful for the preparation of aminosterols
ME02544B (de) * 2005-05-12 2017-02-20 Univ Graz Medizinische 24-norUDCA zur Behandlung der Autoimmunhepatitis
US20110268775A1 (en) 2009-01-06 2011-11-03 Pharmanova, Inc. Nanoparticle pharmaceutical formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1152801B (it) * 1982-08-17 1987-01-14 Proter Spa Composti steroidei ad attivita' coleretica, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo
JPS5955844A (ja) * 1982-09-23 1984-03-31 ピ−ピ−ジ−　インダストリ−ズ　インコ−ポレ−テツド 高障害性フエノ−ル類またはそれらの塩と炭酸エステルとからエ−テルを製造する方法
FR2534735B1 (fr) * 1982-10-15 1985-07-05 Habia Sa Revetement isolant
US4560774A (en) * 1982-11-17 1985-12-24 Arizona State University Macrocyclic lactones
US4539908A (en) * 1982-12-27 1985-09-10 Electronova S.A. Printing unit with an electrostatic printing aid comprising electrodes contained in a lid structure
IT1223313B (it) * 1987-10-20 1990-09-19 Gipharmex Spa Derivati di acidi biliari loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
EP0393494A3 (de) 1992-05-20
EP0393494A2 (de) 1990-10-24
DE69020781T2 (de) 1995-11-30
ES2074492T3 (es) 1995-09-16
CA2014544A1 (en) 1990-10-17
US5057509A (en) 1991-10-15
DK0393494T3 (da) 1995-11-20
GR3017640T3 (en) 1996-01-31
DE69020781D1 (de) 1995-08-17
IT1229569B (it) 1991-09-04
CA2014544C (en) 2001-06-12
EP0393494B1 (de) 1995-07-12
IT8920169A0 (it) 1989-04-17
JPH02292299A (ja) 1990-12-03
JP2816589B2 (ja) 1998-10-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee