DE69020781T2 - Gallensäure-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen daraus. - Google Patents
Gallensäure-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen daraus.Info
- Publication number
- DE69020781T2 DE69020781T2 DE69020781T DE69020781T DE69020781T2 DE 69020781 T2 DE69020781 T2 DE 69020781T2 DE 69020781 T DE69020781 T DE 69020781T DE 69020781 T DE69020781 T DE 69020781T DE 69020781 T2 DE69020781 T2 DE 69020781T2
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- pharmaceutical compositions
- acid derivatives
- bile acid
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8920169A IT1229569B (it) | 1989-04-17 | 1989-04-17 | Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69020781D1 DE69020781D1 (de) | 1995-08-17 |
DE69020781T2 true DE69020781T2 (de) | 1995-11-30 |
Family
ID=11164375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69020781T Expired - Fee Related DE69020781T2 (de) | 1989-04-17 | 1990-04-11 | Gallensäure-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen daraus. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5057509A (de) |
EP (1) | EP0393494B1 (de) |
JP (1) | JP2816589B2 (de) |
AT (1) | ATE124953T1 (de) |
CA (1) | CA2014544C (de) |
DE (1) | DE69020781T2 (de) |
DK (1) | DK0393494T3 (de) |
ES (1) | ES2074492T3 (de) |
GR (1) | GR3017640T3 (de) |
IT (1) | IT1229569B (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5166374A (en) * | 1989-04-17 | 1992-11-24 | Giuliani S.P.A. | Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them |
JP3546886B2 (ja) * | 1993-03-10 | 2004-07-28 | ジェネーラ コーポレーション | ステロイド誘導体、それらを含む薬剤組成物、及び抗生物質又は消毒薬としてのそれらの使用 |
US5856535A (en) * | 1994-08-18 | 1999-01-05 | Magainin Pharmaceuticals, Inc. | Aminosterol ester compounds |
US5840740A (en) * | 1995-06-07 | 1998-11-24 | Magainin Pharmaceuticals Inc. | Aminosterol compounds and a method of treating infection using the aminosterol compounds |
US5795885A (en) * | 1995-06-07 | 1998-08-18 | Magainin Pharmaceuticals Inc. | Method of inhibiting profileration of cells by administering an aminosterol compound |
US5840936A (en) * | 1995-06-07 | 1998-11-24 | Magainin Pharmaceuticals Inc. | Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE) |
US5847172A (en) * | 1995-06-07 | 1998-12-08 | Magainin Pharmaceuticals Inc. | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
US5874597A (en) * | 1995-06-07 | 1999-02-23 | Magainin Pharmaceuticals, Inc. | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
US5763430A (en) * | 1995-06-07 | 1998-06-09 | Magainin Pharmaceuticals Inc. | Method of treating a viral infection by administering a steroid compound |
US5994336A (en) * | 1995-06-07 | 1999-11-30 | Magainin Pharmaceuticals Inc. | Method of inhibiting proliferation of cells by administering an aminosterol compound |
US6143738A (en) * | 1995-06-07 | 2000-11-07 | Magainin Pharmaceuticals, Inc. | Therapeutic uses for an aminosterol compound |
US5792635A (en) * | 1995-06-07 | 1998-08-11 | Magainin Pharmaceuticals, Inc. | Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine |
JP2000510460A (ja) * | 1996-04-26 | 2000-08-15 | マゲイニン・ファーマシューティカルズ・インコーポレーテッド | スクアラミンを他の抗癌剤と併用する上皮性悪性腫瘍の治療 |
US6596712B2 (en) | 1996-04-26 | 2003-07-22 | Genaera Corporation | Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities |
US6262283B1 (en) | 1996-12-06 | 2001-07-17 | Magainin Pharmaceuticals Inc. | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds |
AU5342701A (en) * | 2000-04-12 | 2001-10-30 | Genaera Corp | A process for the preparation of 7.alpha.-hydroxy 3-aminosubstituted sterols using intermediates with an unprotected 7.alpha.-hydroxy group |
HUE030010T2 (en) * | 2005-05-12 | 2017-04-28 | Medizinische Universität Graz | 24-norUDCA for the treatment of autoimmune hepatitis |
US20110268775A1 (en) | 2009-01-06 | 2011-11-03 | Pharmanova, Inc. | Nanoparticle pharmaceutical formulations |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1152801B (it) * | 1982-08-17 | 1987-01-14 | Proter Spa | Composti steroidei ad attivita' coleretica, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo |
JPS5955844A (ja) * | 1982-09-23 | 1984-03-31 | ピ−ピ−ジ− インダストリ−ズ インコ−ポレ−テツド | 高障害性フエノ−ル類またはそれらの塩と炭酸エステルとからエ−テルを製造する方法 |
FR2534735B1 (fr) * | 1982-10-15 | 1985-07-05 | Habia Sa | Revetement isolant |
US4560774A (en) * | 1982-11-17 | 1985-12-24 | Arizona State University | Macrocyclic lactones |
US4539908A (en) * | 1982-12-27 | 1985-09-10 | Electronova S.A. | Printing unit with an electrostatic printing aid comprising electrodes contained in a lid structure |
IT1223313B (it) * | 1987-10-20 | 1990-09-19 | Gipharmex Spa | Derivati di acidi biliari loro preparazione e composizioni farmaceutiche che li contengono |
-
1989
- 1989-04-17 IT IT8920169A patent/IT1229569B/it active
-
1990
- 1990-04-09 US US07/507,260 patent/US5057509A/en not_active Expired - Lifetime
- 1990-04-11 AT AT90106972T patent/ATE124953T1/de not_active IP Right Cessation
- 1990-04-11 DE DE69020781T patent/DE69020781T2/de not_active Expired - Fee Related
- 1990-04-11 JP JP2096160A patent/JP2816589B2/ja not_active Expired - Fee Related
- 1990-04-11 EP EP90106972A patent/EP0393494B1/de not_active Expired - Lifetime
- 1990-04-11 DK DK90106972.4T patent/DK0393494T3/da active
- 1990-04-11 ES ES90106972T patent/ES2074492T3/es not_active Expired - Lifetime
- 1990-04-12 CA CA002014544A patent/CA2014544C/en not_active Expired - Fee Related
-
1995
- 1995-10-04 GR GR950402753T patent/GR3017640T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5057509A (en) | 1991-10-15 |
DK0393494T3 (da) | 1995-11-20 |
JP2816589B2 (ja) | 1998-10-27 |
CA2014544A1 (en) | 1990-10-17 |
CA2014544C (en) | 2001-06-12 |
EP0393494A2 (de) | 1990-10-24 |
ATE124953T1 (de) | 1995-07-15 |
EP0393494B1 (de) | 1995-07-12 |
ES2074492T3 (es) | 1995-09-16 |
EP0393494A3 (de) | 1992-05-20 |
DE69020781D1 (de) | 1995-08-17 |
JPH02292299A (ja) | 1990-12-03 |
GR3017640T3 (en) | 1996-01-31 |
IT1229569B (it) | 1991-09-04 |
IT8920169A0 (it) | 1989-04-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69023947D1 (de) | Fluorierte Gallensäure-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen daraus. | |
DE69020781T2 (de) | Gallensäure-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen daraus. | |
EP0212535B1 (de) | N6-Disubstituierte Purinderivate, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel | |
FI942075A (fi) | Sappihappojohdannaisten tetratsolijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina | |
IL109526A0 (en) | Benzofuranyl- and thiophenyl-alkanecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them | |
GR890300125T1 (en) | Billiary acid derivatives, processes for the preparation thereof and phamaceutical compositions containing them | |
ATE46164T1 (de) | 1,4:3,6-dianhydro-hexit-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
HUT38950A (en) | Process for producing 2-substituted-1,3-propylidene-diphosphonate derivatives and pharmaceutical compositions containing them as active agents | |
DE69821815T2 (de) | Thiocolchicin-Derivate mit entzündungshemmender und muskelrelaxierender Wirkung | |
DE3850603T2 (de) | Arylaralkylether, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzung. | |
DE3882438D1 (de) | Alkansulfonanilid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung. | |
ATE3429T1 (de) | Paromomycin-derivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammenzetzung. | |
NO852514L (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-alkyltio-2-piperazino-pyrimido (5,4-d) pyrimidin-derivater. | |
DE68905363T2 (de) | Heterotetracyclische laktamderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten. | |
ATE70838T1 (de) | Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung. | |
DE3886185D1 (de) | 2-Thiazolidinon-Derivate und diese enthaltende pharmazeutische Präparate, Verfahren zu deren Herstellung und deren Verwendung. | |
ATE9339T1 (de) | 2-(1-piperazinyl)-2,4,6-cycloheptatrien-1-onederivate, verfahren zu ihrer herstellung, zwischenprodukte fuer diese verfahren und deren herstellung und die derivate enthaltende pharmazeutische zusammensetzungen. | |
ATE40118T1 (de) | Benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel. | |
ATE52260T1 (de) | Aminomethyl-6-furo(3,4-c>pyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. | |
ATE36154T1 (de) | 4-phenylaminopyridin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
ES8704463A1 (es) | Procedimiento para preparar 2-(n-alquinil-n-fenilamino)-imidazolinas | |
DE3862426D1 (de) | 2-selenomethyl-1,4-dihydropyridine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
ATE11530T1 (de) | P-chlorophenoxyessigsaeure-derivat, verfahren zu dessen herstellung und pharmazeutische zusammenstellung. | |
HU904013D0 (en) | Process for producing substituted 3-amino-sydnonimine derivatives and pharmaceutical preparatives containing these |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |