ZA9610774B - 3-Amino-2-mercaptoenzoic acid derivatives and processes for their preparation - Google Patents

3-Amino-2-mercaptoenzoic acid derivatives and processes for their preparation

Info

Publication number
ZA9610774B
ZA9610774B ZA9610774A ZA9610774A ZA9610774B ZA 9610774 B ZA9610774 B ZA 9610774B ZA 9610774 A ZA9610774 A ZA 9610774A ZA 9610774 A ZA9610774 A ZA 9610774A ZA 9610774 B ZA9610774 B ZA 9610774B
Authority
ZA
South Africa
Prior art keywords
substituted
unsubstituted
compounds
preparation
carbon atoms
Prior art date
Application number
ZA9610774A
Other languages
English (en)
Inventor
Walter Kunz
Beat Jau
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA9610774B publication Critical patent/ZA9610774B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/12Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by reactions not involving the formation of mercapto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/63Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/20Esters of monothiocarboxylic acids
    • C07C327/26Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/22Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA9610774A 1995-12-21 1996-12-20 3-Amino-2-mercaptoenzoic acid derivatives and processes for their preparation ZA9610774B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH363795 1995-12-21
US08/770,353 US5770758A (en) 1995-12-21 1996-12-20 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation

Publications (1)

Publication Number Publication Date
ZA9610774B true ZA9610774B (en) 1997-06-30

Family

ID=25693502

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9610774A ZA9610774B (en) 1995-12-21 1996-12-20 3-Amino-2-mercaptoenzoic acid derivatives and processes for their preparation

Country Status (21)

Country Link
US (1) US5770758A (xx)
EP (1) EP0780372B3 (xx)
JP (1) JP4217924B2 (xx)
KR (1) KR100470887B1 (xx)
CN (2) CN1078888C (xx)
AT (1) ATE208760T1 (xx)
AU (1) AU713526B2 (xx)
BR (1) BR9606092A (xx)
CA (1) CA2193460C (xx)
CZ (1) CZ291857B6 (xx)
DE (1) DE69616956T3 (xx)
DK (1) DK0780372T3 (xx)
ES (1) ES2168121T7 (xx)
HU (1) HU221600B (xx)
IL (3) IL133900A (xx)
MX (2) MX9606665A (xx)
PL (1) PL187885B1 (xx)
PT (1) PT780372E (xx)
RU (1) RU2176241C2 (xx)
SK (1) SK283840B6 (xx)
ZA (1) ZA9610774B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002013A (en) * 1995-12-21 1999-12-14 Novartis Corporation 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation
GB9724586D0 (en) * 1997-11-20 1998-01-21 Rhone Poulenc Agriculture New herbicides
ES2405594T3 (es) 2002-09-25 2013-05-31 Memory Pharmaceuticals Corporation Idazoles, benzotiazoles y benzisotiazoles, y preparación y usos de los mismos
DE10313887A1 (de) * 2003-03-27 2004-10-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum selektiven Gewinnen von Gold aus goldhaltigen Materialien
DK2368553T3 (en) 2003-04-08 2015-02-09 Progenics Pharm Inc Pharmaceutical preparation comprising methylnaltrexone
WO2005007601A2 (en) * 2003-07-10 2005-01-27 Achillion Pharmaceuticals, Inc. Substituted arylthiourea derivatives useful as inhibitors of viral replication
BRPI0508771A (pt) 2004-03-25 2007-08-14 Memory Pharm Corp indazóis, benzotiazóis, benzoisotiazóis, benzisoxazóis, e a preparação e usos dos mesmos
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
CN101395161A (zh) 2006-03-02 2009-03-25 马林克罗特公司 噻二唑化合物及其在光疗中的用途
PT2565195E (pt) 2007-03-29 2015-07-28 Wyeth Llc Antagonistas e receptor opióide periférico e respectivas utilizações
ES2765811T5 (es) 2007-03-29 2024-02-27 Progenics Pharm Inc Forma cristalina de bromuro de (R)-n-metilnaltrexona y sus usos
EP3064503A1 (en) 2007-03-29 2016-09-07 Progenics Pharmaceuticals, Inc. Peripheral opioid receptor antagonists and uses thereof
EP2240489A1 (en) 2008-02-06 2010-10-20 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
CN101492429B (zh) * 2008-12-10 2010-12-15 上海泰禾(集团)有限公司 一种苯并-[1,2,3]-噻二唑-7-甲酸三氟乙酯的提纯方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150140A (en) * 1976-12-23 1979-04-17 The Upjohn Company Benzothiazolyl oxanic acids, esters and salts
DE2757924A1 (de) * 1977-12-24 1979-07-05 Hoechst Ag Verfahren zur herstellung von vinylchlorid-polymerisaten
DE3601286A1 (de) * 1986-01-17 1987-07-23 Consiglio Nazionale Ricerche Sammelmittel fuer die selektive flotation von blei- und zinkerzen und verfahren zu deren herstellung
ATE82668T1 (de) 1987-08-21 1992-12-15 Ciba Geigy Ag Benzothiadiazole und ihre verwendung in verfahren und mitteln gegen pflanzenkrankheiten.
EP0384889B1 (de) * 1989-02-21 1993-10-13 Ciba-Geigy Ag Mittel zum Schutz von Pflanzen gegen Krankheiten
EP0529600B1 (de) 1991-08-30 1996-11-06 Hoechst Aktiengesellschaft Verfahren zur Herstellung von 2-Aminobenzthiazolen
JPH0690518A (ja) * 1992-09-09 1994-03-29 Toshiba Corp 地絡継電器
JP3310104B2 (ja) * 1994-04-04 2002-07-29 三新化学工業株式会社 2−アミノチオフェノール類の製造方法
MX9702787A (es) * 1994-10-17 1997-06-28 Novartis Ag Proceso para la preparacion de 3-aminobenzonitrilos sustituidos.

Also Published As

Publication number Publication date
EP0780372A2 (en) 1997-06-25
PT780372E (pt) 2002-04-29
CZ377396A3 (en) 1997-07-16
AU713526C (en) 1997-06-26
MXPA02000515A (es) 2002-09-17
HU221600B (hu) 2002-11-28
JP4217924B2 (ja) 2009-02-04
AU713526B2 (en) 1999-12-02
US5770758A (en) 1998-06-23
PL317601A1 (en) 1997-06-23
IL119819A0 (en) 1997-03-18
CN1163491C (zh) 2004-08-25
HUP9603527A2 (en) 1997-09-29
JPH09235279A (ja) 1997-09-09
IL133900A0 (en) 2001-04-30
ES2168121T7 (es) 2013-09-24
EP0780372B1 (en) 2001-11-14
HU9603527D0 (en) 1997-02-28
BR9606092A (pt) 1998-09-01
IL133900A (en) 2004-07-25
IL119819A (en) 2004-07-25
CA2193460A1 (en) 1997-06-22
ATE208760T1 (de) 2001-11-15
CN1156722A (zh) 1997-08-13
DE69616956T2 (de) 2002-06-20
CN1078888C (zh) 2002-02-06
EP0780372B3 (en) 2013-05-22
CA2193460C (en) 2007-03-27
DK0780372T3 (da) 2002-03-11
CN1392144A (zh) 2003-01-22
HUP9603527A3 (en) 1999-04-28
DE69616956D1 (de) 2001-12-20
MX9606665A (es) 1997-06-28
SK283840B6 (sk) 2004-03-02
DE69616956T3 (de) 2014-01-30
ES2168121T3 (es) 2002-06-01
KR100470887B1 (ko) 2005-03-14
RU2176241C2 (ru) 2001-11-27
SK163696A3 (en) 1997-10-08
EP0780372A3 (en) 1997-09-17
PL187885B1 (pl) 2004-10-29
AU7640496A (en) 1997-06-26
CZ291857B6 (cs) 2003-06-18

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