ES2157522T3 - Cepas de vacunas europeas del virus del sindrome respiratorio reproductor porcino (prrsv). - Google Patents

Cepas de vacunas europeas del virus del sindrome respiratorio reproductor porcino (prrsv).

Info

Publication number
ES2157522T3
ES2157522T3 ES97203111T ES97203111T ES2157522T3 ES 2157522 T3 ES2157522 T3 ES 2157522T3 ES 97203111 T ES97203111 T ES 97203111T ES 97203111 T ES97203111 T ES 97203111T ES 2157522 T3 ES2157522 T3 ES 2157522T3
Authority
ES
Spain
Prior art keywords
respiratory syndrome
prrsv
vaccine viruses
reproductive respiratory
european
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97203111T
Other languages
English (en)
Inventor
Woensel Petrus A M Van
Jean G J Demaret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of ES2157522T3 publication Critical patent/ES2157522T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/815Viral vaccine for porcine species, e.g. swine

Abstract

LA PRESENTE INVENCION SE REFIERE A CEPAS EUROPEAS CONTRA EL VIRUS DEL SINDROME REPRODUCTOR Y RESPIRATORIO PORCINO (PRRSV), QUE POSEEN LA CARACTERISTICA UNICA DE QUE NO SON INFECCIOSAS PARA MACROFAGOS, Y A METODOS PARA LA PRODUCCION DE DICHAS CEPAS. LA INVENCION PROPORCIONA ASIMISMO VACUNAS PARA LA PROTECCION DE CERDOS CONTRA EL PRRS, BASADAS EN ESTAS CEPAS, ASI COMO METODOS PARA LA PRODUCCION DE DICHAS VACUNAS.
ES97203111T 1996-10-09 1997-10-07 Cepas de vacunas europeas del virus del sindrome respiratorio reproductor porcino (prrsv). Expired - Lifetime ES2157522T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96202804 1996-10-09

Publications (1)

Publication Number Publication Date
ES2157522T3 true ES2157522T3 (es) 2001-08-16

Family

ID=8224476

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97203111T Expired - Lifetime ES2157522T3 (es) 1996-10-09 1997-10-07 Cepas de vacunas europeas del virus del sindrome respiratorio reproductor porcino (prrsv).

Country Status (12)

Country Link
US (1) US5925359A (es)
EP (1) EP0835930B1 (es)
JP (2) JP4152462B2 (es)
KR (1) KR100484041B1 (es)
AT (1) ATE199022T1 (es)
BR (1) BR9705009A (es)
CA (1) CA2217882C (es)
DE (1) DE69704011T2 (es)
DK (1) DK0835930T3 (es)
ES (1) ES2157522T3 (es)
GR (1) GR3035712T3 (es)
PT (1) PT835930E (es)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0587780T4 (da) * 1991-06-06 2008-10-13 Boehringer Ingelheim Vetmed Smitstof, som forårsager Mystery Swine Disease,vaccinepræparater og diagnostiske sæt
USRE39494E1 (en) * 1992-02-27 2007-02-27 Intervet Inc. Inactivated mycoplasma hyopneumoniae and uses therefor
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
AU769539B2 (en) 1999-01-29 2004-01-29 Zoetis Services Llc Adjuvants for use in vaccines
CA2366072C (en) 1999-03-08 2007-07-10 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
EP2251419B1 (en) * 1999-04-22 2012-05-30 United States Department of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate JA-142
SG83740A1 (en) * 1999-08-10 2001-10-16 Inst Of Molecular Agrobiology An attenuated porcine reproductive and respiratory syndrome virus strain and methods of use
WO2002078742A2 (en) * 2001-01-30 2002-10-10 The Lauridsen Group, Incorporated Methods and compositions for treatment of immune dysfunction disorders
AU2002309486A1 (en) * 2001-01-30 2002-10-15 The Lauridsen Group, Incorporated Methods and compositions for modulating the immune system of animals
US20030103962A1 (en) * 2001-10-09 2003-06-05 Campbell Joy M. Methods and compositions for modulating the immune system of animals
US20030190314A1 (en) * 2001-01-30 2003-10-09 The Lauridsen Group Methods and compositions of treatment for modulating the immune system of animals
US20030099633A1 (en) * 2001-10-09 2003-05-29 Campbell Joy M. Methods and compositions for treatment of immune dysfunction disorders
SE0300795D0 (sv) * 2003-03-24 2003-03-24 Isconova Ab Composition comprising iscom particles and live micro-organisms
KR20050040172A (ko) * 2003-10-27 2005-05-03 주식회사 중앙백신연구소 돼지 생식기호흡기 증후군 바이러스 불활화 백신의 제조방법
CA2552328A1 (en) * 2004-01-15 2005-08-04 Intervet International B.V. Non-animal origin stabilizers and processes for producing the same
MXPA06015105A (es) 2004-06-18 2007-03-26 Univ Minnesota Identificacion de organismos viralmente infectados y vacunados.
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
BRPI0518353A2 (pt) * 2004-11-19 2008-11-18 Intervet Int Bv composiÇço imunogÉnica, vÍrus de sÍndrome respiratària e reprodutiva porcina atenuado, e, mÉtodo para proteger um suÍno contra a sÍndrome respiratària e reprodutiva porcina
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US7572620B2 (en) 2005-01-11 2009-08-11 Wisconsin Alumni Research Foundation H3 equine influenza A virus
ES2343201T3 (es) 2005-01-13 2010-07-26 Boehringer Ingelheim Vetmedica Gmbh Vacunas contra el srrp.
CN101107009B (zh) 2005-01-20 2014-08-06 伊斯克诺瓦公司 包含纤连蛋白结合蛋白或纤连蛋白结合肽的疫苗组合物
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
PL2369001T3 (pl) 2005-06-24 2017-06-30 Regents Of The University Of Minnesota Wirusy PRRS, ich klony zakaźne, mutanty i sposoby stosowania
JP5106398B2 (ja) * 2005-09-09 2012-12-26 インターベツト・インターナシヨナル・ベー・ベー Pcv−2ワクチン
MY149398A (en) 2005-12-29 2013-08-30 Boehringer Ingelheim Vetmed Multivalent pcv2 immunogenic compositions and methods of producing such compositions
MX338626B (es) 2005-12-29 2016-04-26 Boehringer Ingelheim Vetmed Uso de una composicion inmunogenica de pcv2 para producir los sintomas clinicos en cerdos.
CA2646574C (en) * 2006-04-10 2012-08-21 Intervet International B.V. Vaccine against mycoplasma and prrsv
US20100129397A1 (en) * 2006-12-11 2010-05-27 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
PT2481420T (pt) * 2006-12-15 2019-05-31 Boehringer Ingelheim Animal Health Usa Inc Vacina para porcos anti-pcv2 de dose única
EP1941903A1 (en) * 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
CN101668846B (zh) * 2007-01-12 2014-03-12 伊利诺伊大学评议会 用于猪繁殖与呼吸综合征(prrs)病毒生长的非猿猴细胞
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
CN101932336B (zh) * 2007-12-31 2014-07-09 贝林格尔.英格海姆维特梅迪卡有限公司 有外来氨基酸插入的pcv2 orf2病毒样颗粒
US20090317423A1 (en) * 2008-01-23 2009-12-24 Boehringer Ingelheim Vetmedica, Inc. Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions
KR101653177B1 (ko) * 2008-08-25 2016-09-01 베링거잉겔하임베트메디카인코퍼레이티드 고병원성 돼지 생식기 및 호흡기 증후군(hp prrs)에 대한 백신
KR101125244B1 (ko) * 2008-09-19 2012-03-21 전남대학교산학협력단 돼지생식기호흡기증후군 바이러스(prrsv)의 gp5를 발현하는 약독화된 보르데텔라 브론키셉티카 균주를 포함하는 prrsv 감염증 예방 또는 치료용 조성물, 및 그의 제조 방법
JP5306943B2 (ja) * 2009-08-24 2013-10-02 全国農業協同組合連合会 弱毒ウイルスの作出方法
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
MX346636B (es) 2011-02-17 2017-03-27 Boehringer Ingelheim Vetmedica Gmbh Procedimiento para la produccion a escala comercial de prrsv.
EA035624B1 (ru) 2011-02-17 2020-07-16 Бёрингер Ингельхайм Ветмедика Гмбх Вирулентный и ослабленный штаммы вируса репродуктивно-респираторного синдрома свиней (prrsv) европейского типа
US9592286B2 (en) 2011-05-27 2017-03-14 Sinovet (Beijing) Biotechnology Co., Ltd. Combined vaccines for prevention of porcine virus infections
CN102727884B (zh) * 2011-10-27 2014-05-14 华威特(北京)生物科技有限公司 猪繁殖与呼吸综合征、伪狂犬病二联活疫苗及其制备方法
CN102727882B (zh) * 2011-10-27 2014-05-14 华威特(北京)生物科技有限公司 猪繁殖与呼吸综合征、猪瘟、伪狂犬病的三联活疫苗及其制备方法
EP2737058A1 (en) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
CN102973932A (zh) * 2011-09-07 2013-03-20 普莱柯生物工程股份有限公司 猪繁殖与呼吸综合征、猪圆环病毒病与猪伪狂犬病三联灭活疫苗以及其制备方法
CA2871786C (en) * 2012-04-24 2021-11-16 Ohio State Innovation Foundation Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome
EP2968513A2 (en) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
KR20160046879A (ko) 2013-09-25 2016-04-29 조에티스 서비시즈 엘엘씨 Pcv2b 분지형 백신 조성물 및 사용 방법
EA035265B1 (ru) 2013-10-02 2020-05-21 Бёрингер Ингельхайм Энимал Хелс Ю-Эс-Эй Инк. Вариант белка opc2 pcv2 и содержащие его вирусоподобные частицы
MX2016007737A (es) 2013-12-20 2016-09-07 Boehringer Ingelheim Vetmedica Gmbh Variante del virus prrs, clon de adnc del virus europeo y sus usos.
CN108135993B (zh) 2015-08-31 2022-03-22 贝林格尔·英格海姆维特梅迪卡有限公司 用于先天性震颤的瘟病毒疫苗
US10188725B2 (en) 2015-12-14 2019-01-29 Elanco Us Inc. Hybrid core feline vaccines
CA3042584A1 (en) * 2016-11-03 2018-05-11 Boehringer Ingelheim Vetmedica Gmbh Vaccine against porcine parvovirus and porcine reproductive and respiratory syndrome virus and methods of production thereof
MX2021012051A (es) 2019-04-04 2022-01-18 Boehringer Ingelheim Animal Health Usa Inc Vacunas para circovirus porcino tipo 3 (pcv3), y produccion y sus usos.
BR112023001324A2 (pt) 2020-07-24 2023-02-14 Boehringer Ingelheim Animal Health Usa Inc Combinação de vacina de suíno
CN113801854B (zh) * 2021-08-27 2023-02-28 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 分泌欧洲型猪繁殖与呼吸综合征病毒特异性单克隆抗体的杂交瘤细胞系及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62192325A (ja) * 1986-02-15 1987-08-22 ザ・ウイスタ−・インステイチユ−ト・オブ・アナトミ−・アンド・バイオロジ− ワクチン、その製造法及びヒトのロ−タウイルス感染症に対するワクチン接種における使用
EP0610250B2 (en) * 1991-10-14 2008-10-29 Intervet International BV Porcine reproductive respiratory syndrome (prrs) vaccine and diagnostic
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
ES2152304T3 (es) * 1993-02-08 2001-02-01 Bayer Ag Procedimiento para el crecimiento del virus del sindrome reproductivo y respiratorio porcino y su uso en vacunas.
EP0676467B1 (en) * 1994-04-11 2001-10-04 Akzo Nobel N.V. European vaccine strains of the porcine reproductive respiratory syndrome virus (PRRSV)

Also Published As

Publication number Publication date
DE69704011T2 (de) 2001-06-07
EP0835930B1 (en) 2001-01-31
PT835930E (pt) 2001-06-29
MX9707780A (es) 1998-08-30
JP4152462B2 (ja) 2008-09-17
DK0835930T3 (da) 2001-06-18
ATE199022T1 (de) 2001-02-15
DE69704011D1 (de) 2001-03-08
JP2007320963A (ja) 2007-12-13
CA2217882A1 (en) 1998-04-09
KR100484041B1 (ko) 2005-08-18
CA2217882C (en) 2007-05-22
JPH10117773A (ja) 1998-05-12
GR3035712T3 (en) 2001-07-31
EP0835930A1 (en) 1998-04-15
BR9705009A (pt) 1998-10-27
KR19980032672A (ko) 1998-07-25
US5925359A (en) 1999-07-20

Similar Documents

Publication Publication Date Title
ES2157522T3 (es) Cepas de vacunas europeas del virus del sindrome respiratorio reproductor porcino (prrsv).
HUP9802493A2 (hu) A rejtélyes sertésbetegség elleni vakcina, eljárás ennek előállítására, és alkalmazása
ES2089316T3 (es) Agente viral asociado con la enfermedad porcina misteriosa (mystery swine desease).
DE69522984T2 (de) Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Schweins
ATE131067T1 (de) Impfstoff gegen das fortpflanzungs- und atmungssyndrom bei schweinen (prrs) und diagnose.
HUP9801124A2 (hu) Sertés reproduktív-respirációs szindrómát (PRRS) okozó új, attenuált vírus törzs, az ezzel előállított vakcinák és diagnosztikai készletek, valamint eljárás ezek előállítására
DE69837992D1 (de) Prrsv-antigene, die auf peptidsequenzen des prrs-virus basieren, für die verwendung als impfstoff und für diagnostische tests
ES8505819A1 (es) Un procedimiento de una vacuna capaz de inducir la produccion de anticuerpos de reaccion con mas de una cepa de virus dela influenza.
NO20001768D0 (no) Viruskapsomervaksine, fremgangsmåte til fremstilling samt anvendelse derav
HUP9901958A2 (hu) Sertés reproduktív és respirációs szindróma vakcina
ATE392429T1 (de) Lebend-impfstoff gegen heliobacter pylori
ZA891371B (en) Live combination vaccine
ES2055610T3 (es) Vacuna contra hrsv.
ES2074965B1 (es) Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen.
EP0563288A4 (en) Immunopotentiation of vaccines, particularly swine pleuropneumonia vaccines
RU96116250A (ru) Штамм pestivirus, используемый для изготовления лапинизированной вирус вакцины против классической чумы свиней
FI893346A (fi) Icke-reverterande rna-virus.
ES2078187B1 (es) Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 835930

Country of ref document: ES