DE69704011D1 - Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Sweins (PRRSV) - Google Patents

Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Sweins (PRRSV)

Info

Publication number
DE69704011D1
DE69704011D1 DE69704011T DE69704011T DE69704011D1 DE 69704011 D1 DE69704011 D1 DE 69704011D1 DE 69704011 T DE69704011 T DE 69704011T DE 69704011 T DE69704011 T DE 69704011T DE 69704011 D1 DE69704011 D1 DE 69704011D1
Authority
DE
Germany
Prior art keywords
respiratory syndrome
prrsv
reproductive system
syndrome virus
vaccine strains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69704011T
Other languages
English (en)
Other versions
DE69704011T2 (de
Inventor
Woensel Petrus A M Van
Jean G J Demaret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE69704011D1 publication Critical patent/DE69704011D1/de
Application granted granted Critical
Publication of DE69704011T2 publication Critical patent/DE69704011T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/815—Viral vaccine for porcine species, e.g. swine
DE1997604011 1996-10-09 1997-10-07 Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Sweins (PRRSV) Expired - Lifetime DE69704011T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96202804 1996-10-09

Publications (2)

Publication Number Publication Date
DE69704011D1 true DE69704011D1 (de) 2001-03-08
DE69704011T2 DE69704011T2 (de) 2001-06-07

Family

ID=8224476

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1997604011 Expired - Lifetime DE69704011T2 (de) 1996-10-09 1997-10-07 Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Sweins (PRRSV)

Country Status (12)

Country Link
US (1) US5925359A (de)
EP (1) EP0835930B1 (de)
JP (2) JP4152462B2 (de)
KR (1) KR100484041B1 (de)
AT (1) ATE199022T1 (de)
BR (1) BR9705009A (de)
CA (1) CA2217882C (de)
DE (1) DE69704011T2 (de)
DK (1) DK0835930T3 (de)
ES (1) ES2157522T3 (de)
GR (1) GR3035712T3 (de)
PT (1) PT835930E (de)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA27788C2 (uk) * 1991-06-06 2000-10-16 Стіхтінг Сентрал Діргенескюндіг Інстітют Композиція, що містить виділений фактор лелістада, вакцинна композиція для вакцинації тварин (варіанти), діагностичний набір для виявлення антитіла
USRE39494E1 (en) * 1992-02-27 2007-02-27 Intervet Inc. Inactivated mycoplasma hyopneumoniae and uses therefor
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (de) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
AU769539B2 (en) 1999-01-29 2004-01-29 Zoetis Services Llc Adjuvants for use in vaccines
AU3198200A (en) * 1999-03-08 2000-09-28 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
ATE474041T1 (de) * 1999-04-22 2010-07-15 Us Agriculture Auf dem isolat ja-142 basierender impfstoff gegen das reproduktive-und-respiratorische syndrom beim schwein
SG83740A1 (en) * 1999-08-10 2001-10-16 Inst Of Molecular Agrobiology An attenuated porcine reproductive and respiratory syndrome virus strain and methods of use
WO2002078741A2 (en) * 2001-01-30 2002-10-10 The Lauridsen Group, Incorporated Methods and compositions for modulating the immune system of animals
WO2002078742A2 (en) * 2001-01-30 2002-10-10 The Lauridsen Group, Incorporated Methods and compositions for treatment of immune dysfunction disorders
US20030190314A1 (en) * 2001-01-30 2003-10-09 The Lauridsen Group Methods and compositions of treatment for modulating the immune system of animals
US20030099633A1 (en) * 2001-10-09 2003-05-29 Campbell Joy M. Methods and compositions for treatment of immune dysfunction disorders
US20030103962A1 (en) * 2001-10-09 2003-06-05 Campbell Joy M. Methods and compositions for modulating the immune system of animals
SE0300795D0 (sv) * 2003-03-24 2003-03-24 Isconova Ab Composition comprising iscom particles and live micro-organisms
KR20050040172A (ko) * 2003-10-27 2005-05-03 주식회사 중앙백신연구소 돼지 생식기호흡기 증후군 바이러스 불활화 백신의 제조방법
US7435422B2 (en) * 2004-01-15 2008-10-14 Intervet International B.V. Non-animal origin stabilizers and processes for producing the same
KR20070028547A (ko) 2004-06-18 2007-03-12 리전츠 오브 더 유니버스티 오브 미네소타 바이러스에 감염되고 백신접종된 생물의 동정
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
PL1833508T3 (pl) * 2004-11-19 2011-02-28 Intervet Int Bv Szczepy świńskiego wirusa zespołu rozrodczo-oddechowego i ich kompozycje
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US7572620B2 (en) 2005-01-11 2009-08-11 Wisconsin Alumni Research Foundation H3 equine influenza A virus
KR20070096019A (ko) 2005-01-13 2007-10-01 베링거잉겔하임베트메디카게엠베하 향상된 ｐｒｒｓ 백신
BRPI0606481A2 (pt) 2005-01-20 2009-06-30 Isconova Ab composição de vacina compreendendo uma proteìna de ligação a fibronectina ou um peptìdeo de ligação a fibronectina
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
CA2894069C (en) 2005-06-24 2019-02-26 Regents Of The University Of Minnesota Prrs viruses, infectious clones, mutants thereof, and methods of use
KR101347503B1 (ko) * 2005-09-09 2014-01-02 인터벳 인터내셔널 비.브이. Ｐｃｖ-2 백신
EP3320919B1 (de) * 2005-12-29 2020-05-27 Boehringer Ingelheim Animal Health USA Inc. Multivalente immunogene pcv2-zusammensetzungen und verfahren zur herstellung solcher zusammensetzungen
DK2371385T3 (en) * 2005-12-29 2015-11-30 Boehringer Ingelheim Vetmed Use of a PV2 immunogen composition for reduction of clinical symptoms in pigs
PL2007419T3 (pl) * 2006-04-10 2012-09-28 Intervet Int Bv Szczepionka przeciwko mykoplazmie i PRRSV
EP2859900A1 (de) * 2006-12-11 2015-04-15 Boehringer Ingelheim Vetmedica, Inc. Wirksames Verfahren zur Behandlung von Infektionen mit dem porcinen Circovirus und Lawsonia intracellularis
AU2007333857B2 (en) * 2006-12-15 2014-05-15 Boehringer Ingelheim Animal Health USA Inc. Treatment of pigs with PCV2 antigen
EP1941903A1 (de) * 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxe und Behandlung von PRDC
US8202717B2 (en) * 2007-01-12 2012-06-19 The Board Of Trustees Of The University Of Illinois Non-simian cells for growth of porcine reproductive and respiratory syndrome (PRRS) virus
EP1958644A1 (de) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Vorbeugung und Behandlung von subklinischer PCVD
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
BRPI0821456A2 (pt) * 2007-12-31 2015-06-16 Boehring Ingelheim Vetmedica Inc Partícula similar à pcv2 orf2 com inserção de aminoácido estranho
CA2712006A1 (en) 2008-01-23 2009-10-15 Boehringer Ingelheim Vetmedica, Inc. Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions
RU2561595C2 (ru) * 2008-08-25 2015-08-27 Бёрингер Ингельхайм Ветмедика, Инк. Вакцина против высокопатогенного репродуктивно-респираторного синдрома свиней (hp prrs)
KR101125244B1 (ko) * 2008-09-19 2012-03-21 전남대학교산학협력단 돼지생식기호흡기증후군 바이러스(ｐｒｒｓｖ)의 ｇｐ5를 발현하는 약독화된 보르데텔라 브론키셉티카 균주를 포함하는 ｐｒｒｓｖ 감염증 예방 또는 치료용 조성물, 및 그의 제조 방법
JP5306943B2 (ja) * 2009-08-24 2013-10-02 全国農業協同組合連合会 弱毒ウイルスの作出方法
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
US8765142B2 (en) 2011-02-17 2014-07-01 Boehringer Ingelheim Vetmedica Gmbh European PRRSV strain
BR112013020966B1 (pt) 2011-02-17 2020-05-26 Boehringer Ingelheim Vetmedica Gmbh Processo em escala comercial para produção do prrsv
BR112013030321A2 (pt) 2011-05-27 2017-07-11 Sinovet Beijing Biotechnology Co Ltd composição de vacina, método para preparar a composição de vacina, uso da composição de vacina, método para imunizar um porco, cepa de vacina contra csfv e uso de uma célula no cultivo de uma cepa de vacina contra csfv.
CN102727882B (zh) * 2011-10-27 2014-05-14 华威特（北京）生物科技有限公司 猪繁殖与呼吸综合征、猪瘟、伪狂犬病的三联活疫苗及其制备方法
CN102727884B (zh) * 2011-10-27 2014-05-14 华威特（北京）生物科技有限公司 猪繁殖与呼吸综合征、伪狂犬病二联活疫苗及其制备方法
WO2013017570A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh Novel prrs virus inducing type i interferon in susceptible cells
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
CN102973932A (zh) * 2011-09-07 2013-03-20 普莱柯生物工程股份有限公司 猪繁殖与呼吸综合征、猪圆环病毒病与猪伪狂犬病三联灭活疫苗以及其制备方法
CA2871786C (en) * 2012-04-24 2021-11-16 Ohio State Innovation Foundation Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome
CN105073130A (zh) 2013-03-15 2015-11-18 勃林格殷格翰动物保健公司 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法
KR20160046879A (ko) 2013-09-25 2016-04-29 조에티스 서비시즈 엘엘씨 Pcv2b 분지형 백신 조성물 및 사용 방법
WO2015051099A1 (en) 2013-10-02 2015-04-09 Boehringer Ingelheim Vetmedica, Inc. Pcv2 orf2 protein variant and virus like particles composed thereof
MX2016007737A (es) 2013-12-20 2016-09-07 Boehringer Ingelheim Vetmedica Gmbh Variante del virus prrs, clon de adnc del virus europeo y sus usos.
US9920302B2 (en) 2015-08-31 2018-03-20 Boehringer Ingelheim Vetmedica Gmbh Pestivirus vaccines for congenital tremors
US10188725B2 (en) 2015-12-14 2019-01-29 Elanco Us Inc. Hybrid core feline vaccines
RS64144B1 (sr) 2016-11-03 2023-05-31 Boehringer Ingelheim Vetmedica Gmbh Vakcina protiv svinjskog parvovirusa i virusa reproduktivnog i respiratornog sindroma svinja i postupci njegove proizvodnje
CN114222579A (zh) 2019-04-04 2022-03-22 勃林格殷格翰动物保健美国有限公司 猪圆环病毒3型（pcv3）疫苗及其生产和用途
JP2023535066A (ja) 2020-07-24 2023-08-15 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 組合せブタワクチン
CN113801854B (zh) * 2021-08-27 2023-02-28 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 分泌欧洲型猪繁殖与呼吸综合征病毒特异性单克隆抗体的杂交瘤细胞系及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62192325A (ja) * 1986-02-15 1987-08-22 ザ・ウイスタ−・インステイチユ−ト・オブ・アナトミ−・アンド・バイオロジ− ワクチン、その製造法及びヒトのロ−タウイルス感染症に対するワクチン接種における使用
AU2684792A (en) * 1991-10-14 1993-05-21 Akzo Nobel N.V. Porcine reproductive respiratory syndrome vaccine and diagnostic
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
KR100374295B1 (ko) * 1993-02-08 2003-12-24 바이엘 코포레이션 돼지생식및호흡증후군바이러스의생육방법과백신에서그의용도
DE69522984T2 (de) * 1994-04-11 2002-04-25 Akzo Nobel Nv Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Schweins

Also Published As

Publication number Publication date
CA2217882C (en) 2007-05-22
ATE199022T1 (de) 2001-02-15
KR100484041B1 (ko) 2005-08-18
MX9707780A (es) 1998-08-30
JP2007320963A (ja) 2007-12-13
PT835930E (pt) 2001-06-29
GR3035712T3 (en) 2001-07-31
EP0835930B1 (de) 2001-01-31
CA2217882A1 (en) 1998-04-09
ES2157522T3 (es) 2001-08-16
DE69704011T2 (de) 2001-06-07
US5925359A (en) 1999-07-20
KR19980032672A (ko) 1998-07-25
DK0835930T3 (da) 2001-06-18
JP4152462B2 (ja) 2008-09-17
BR9705009A (pt) 1998-10-27
JPH10117773A (ja) 1998-05-12
EP0835930A1 (de) 1998-04-15

Similar Documents

Publication Publication Date Title
DE69704011T2 (de) Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Sweins (PRRSV)
HUP9802493A2 (hu) A rejtélyes sertésbetegség elleni vakcina, eljárás ennek előállítására, és alkalmazása
ATE206455T1 (de) Europäische vakzinstämme des fortplanzungs- atmungs-syndromsvirus des schweins
ES2089316T3 (es) Agente viral asociado con la enfermedad porcina misteriosa (mystery swine desease).
DE69837992D1 (de) Prrsv-antigene, die auf peptidsequenzen des prrs-virus basieren, für die verwendung als impfstoff und für diagnostische tests
HUP9801124A3 (en) New attenuated strain of the virus causing the porcine reproductive respiratory syndrome (prrs), vaccines and diagnostic means obtainable with said strain, and production process
NO20001768D0 (no) Viruskapsomervaksine, fremgangsmåte til fremstilling samt anvendelse derav
HUP9901958A2 (hu) Sertés reproduktív és respirációs szindróma vakcina
ATE392429T1 (de) Lebend-impfstoff gegen heliobacter pylori
DE69835424D1 (de) Boviner atmungs- und darmcoronavirus als impfstoff
ES2055610T3 (es) Vacuna contra hrsv.
DE3279264D1 (en) Method of immunizing pigs against aujeszky's disease
BR9711138A (pt) Prepara-{es de herperv¡rus equino com prote-Æo mÚtua e m-todo de fazer e usar as mesmas
ES2074965B1 (es) Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen.
RU96116250A (ru) Штамм pestivirus, используемый для изготовления лапинизированной вирус вакцины против классической чумы свиней
UA23884A (uk) Спосіб підвищення імунітету у сільськогосподарськи х птиць при вакцинації її живими вірус-вакцинами

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: INTERVET INTERNATIONAL B. V., AN BOXMEER, NL