HUP9801124A2 - Sertés reproduktív-respirációs szindrómát (PRRS) okozó új, attenuált vírus törzs, az ezzel előállított vakcinák és diagnosztikai készletek, valamint eljárás ezek előállítására - Google Patents

Sertés reproduktív-respirációs szindrómát (PRRS) okozó új, attenuált vírus törzs, az ezzel előállított vakcinák és diagnosztikai készletek, valamint eljárás ezek előállítására

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Publication number
HUP9801124A2
HUP9801124A2 HU9801124A HUP9801124A HUP9801124A2 HU P9801124 A2 HUP9801124 A2 HU P9801124A2 HU 9801124 A HU9801124 A HU 9801124A HU P9801124 A HUP9801124 A HU P9801124A HU P9801124 A2 HUP9801124 A2 HU P9801124A2
Authority
HU
Hungary
Prior art keywords
strain
prrs
vaccines
respiratory syndrome
porcine reproductive
Prior art date
Application number
HU9801124A
Other languages
English (en)
Inventor
Reina Alemany Burch
Enric EspuĄa Maso
Pere Riera Pujadas
Narcis Saubi Roca
Original Assignee
Laboratorios Hipra, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Hipra, S.A. filed Critical Laboratorios Hipra, S.A.
Publication of HUP9801124A2 publication Critical patent/HUP9801124A2/hu
Publication of HUP9801124A3 publication Critical patent/HUP9801124A3/hu

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10061—Methods of inactivation or attenuation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/815—Viral vaccine for porcine species, e.g. swine

Abstract

A találmány a sertés reprődűktív respirációs szindróma (pőrcinereprődűctive respiratőry syndrőme = PRRS) néven ismertsertésbetegséget őkőzó vírűs egy új attenűált törzsére (CNCM PasteűrIntézet I-1642) vőnatkőzik. A leírás ismerteti a törzs attenűálására(gyengítésére) és replikálására szőlgáló eljárást, amelyben a MA-104majőmvese-sejtekből kapőtt új klónt (CNCM Pasteűr Intézet I-1643)használják. Az említett új attenűált törzs, amely sertésekbenártalmatlan és magas imműnőgén aktivitású, őlyan vakcinák ésdiagnősztikai készletek előállítására alkalmas, amelyek lehetővéteszik a PRRS kőrai diagnózisát és az ilyen betegség hatékőnypreventív kezelését. ŕ
HU9801124A 1996-01-25 1996-12-04 New attenuated strain of the virus causing the porcine reproductive respiratory syndrome (prrs), vaccines and diagnostic means obtainable with said strain, and production process HUP9801124A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09600168A ES2102971B1 (es) 1996-01-25 1996-01-25 Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.

Publications (2)

Publication Number Publication Date
HUP9801124A2 true HUP9801124A2 (hu) 1998-08-28
HUP9801124A3 HUP9801124A3 (en) 1999-09-28

Family

ID=8293550

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801124A HUP9801124A3 (en) 1996-01-25 1996-12-04 New attenuated strain of the virus causing the porcine reproductive respiratory syndrome (prrs), vaccines and diagnostic means obtainable with said strain, and production process

Country Status (13)

Country Link
US (1) US6001370A (hu)
EP (1) EP0835929A1 (hu)
JP (1) JP3068204B2 (hu)
KR (1) KR19980703268A (hu)
CN (1) CN1185806A (hu)
BR (1) BR9604888A (hu)
CA (1) CA2216436A1 (hu)
CZ (1) CZ286766B6 (hu)
ES (1) ES2102971B1 (hu)
HU (1) HUP9801124A3 (hu)
PL (1) PL185841B1 (hu)
UA (1) UA68326C2 (hu)
WO (1) WO1997027288A1 (hu)

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US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
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US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
DE60041912D1 (de) 1999-02-10 2009-05-14 Serono Genetics Inst Sa Polymorphe marker des lsr-gens
AU3198200A (en) 1999-03-08 2000-09-28 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
ATE474041T1 (de) * 1999-04-22 2010-07-15 Us Agriculture Auf dem isolat ja-142 basierender impfstoff gegen das reproduktive-und-respiratorische syndrom beim schwein
SG83740A1 (en) * 1999-08-10 2001-10-16 Inst Of Molecular Agrobiology An attenuated porcine reproductive and respiratory syndrome virus strain and methods of use
US7338787B2 (en) 2000-01-14 2008-03-04 Serono Genetics Institute S.A. Nucleic acids encoding OBG3 globular head and uses thereof
EP1156111A1 (en) 2000-05-19 2001-11-21 Stichting Dienst Landbouwkundig Onderzoek Chimeric arterivirus-like particles
CA2427787C (en) 2000-12-07 2012-07-17 Syngenta Limited Herbicide resistant plants
WO2002078741A2 (en) * 2001-01-30 2002-10-10 The Lauridsen Group, Incorporated Methods and compositions for modulating the immune system of animals
KR20050040172A (ko) * 2003-10-27 2005-05-03 주식회사 중앙백신연구소 돼지 생식기호흡기 증후군 바이러스 불활화 백신의 제조방법
KR20070028547A (ko) * 2004-06-18 2007-03-12 리전츠 오브 더 유니버스티 오브 미네소타 바이러스에 감염되고 백신접종된 생물의 동정
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TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
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Also Published As

Publication number Publication date
CA2216436A1 (en) 1997-07-31
BR9604888A (pt) 1998-12-15
PL322455A1 (en) 1998-02-02
EP0835929A1 (en) 1998-04-15
MX9707302A (es) 1998-06-30
JPH10507372A (ja) 1998-07-21
UA68326C2 (en) 2004-08-16
CN1185806A (zh) 1998-06-24
KR19980703268A (ko) 1998-10-15
CZ337797A3 (cs) 1998-03-18
ES2102971A1 (es) 1997-08-01
PL185841B1 (pl) 2003-08-29
CZ286766B6 (en) 2000-06-14
JP3068204B2 (ja) 2000-07-24
US6001370A (en) 1999-12-14
ES2102971B1 (es) 1998-03-01
HUP9801124A3 (en) 1999-09-28
WO1997027288A1 (es) 1997-07-31

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