DE69206631D1 - Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Schweinen (PRRS) und Diagnose. - Google Patents

Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Schweinen (PRRS) und Diagnose.

Info

Publication number
DE69206631D1
DE69206631D1 DE69206631T DE69206631T DE69206631D1 DE 69206631 D1 DE69206631 D1 DE 69206631D1 DE 69206631 T DE69206631 T DE 69206631T DE 69206631 T DE69206631 T DE 69206631T DE 69206631 D1 DE69206631 D1 DE 69206631D1
Authority
DE
Germany
Prior art keywords
respiratory syndrome
prrs
diagnosis
syndrome vaccine
pig reproductive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69206631T
Other languages
English (en)
Other versions
DE69206631T2 (de
Inventor
Nicolaas Visser
Volker Ohlinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8207942&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69206631(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE69206631D1 publication Critical patent/DE69206631D1/de
Application granted granted Critical
Publication of DE69206631T2 publication Critical patent/DE69206631T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69206631T 1991-10-14 1992-10-09 Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Schweinen (PRRS) und Diagnose. Expired - Lifetime DE69206631T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91202646 1991-10-14
PCT/EP1992/002331 WO1993007898A1 (en) 1991-10-14 1992-10-09 Porcine reproductive respiratory syndrome vaccine and diagnostic

Publications (2)

Publication Number Publication Date
DE69206631D1 true DE69206631D1 (de) 1996-01-18
DE69206631T2 DE69206631T2 (de) 1996-05-15

Family

ID=8207942

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69206631T Expired - Lifetime DE69206631T2 (de) 1991-10-14 1992-10-09 Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Schweinen (PRRS) und Diagnose.

Country Status (12)

Country Link
US (1) US6033844A (de)
EP (1) EP0610250B2 (de)
JP (1) JPH07501049A (de)
AT (1) ATE131067T1 (de)
AU (1) AU2684792A (de)
CA (1) CA2121241C (de)
DE (1) DE69206631T2 (de)
DK (1) DK0610250T4 (de)
ES (1) ES2083764T5 (de)
GR (1) GR3019112T3 (de)
HU (1) HU220113B (de)
WO (1) WO1993007898A1 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0587780B2 (de) * 1991-06-06 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6251397B1 (en) * 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
US5695766A (en) 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
ES2152304T3 (es) * 1993-02-08 2001-02-01 Bayer Ag Procedimiento para el crecimiento del virus del sindrome reproductivo y respiratorio porcino y su uso en vacunas.
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
DE4407489A1 (de) * 1994-03-07 1995-09-14 Bayer Ag Vakzine zur Prävention von Respirations- und Reproduktionserkrankungen des Schweines
ES2165405T3 (es) * 1994-04-11 2002-03-16 Akzo Nobel Nv Cepas de vacuna europeas del virus del sindrome reproductor y respiratorio porcino (prrsv).
GB2289279B (en) * 1994-05-13 1998-09-16 Iberica Cyanamid Diagnostic kits and vaccines containing recombinant PRRSV proteins
US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof
ES2102971B1 (es) * 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
SK119498A3 (en) * 1996-03-01 1999-07-12 Schering Corp Porcine reproductive and respiratory syndrome vaccine
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
DK0835930T3 (da) * 1996-10-09 2001-06-18 Akzo Nobel Nv Europæiske vaccinestammer af porcint reproduktions- og respirationssyndrom-virus. (PRRSV)
EP0839912A1 (de) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren
WO2000053787A1 (en) 1999-03-08 2000-09-14 Id-Lelystad, Instituut Voor Dierhouderij En Dierg Ezondheid B.V. Prrsv vaccines
AU754938B2 (en) 1997-05-06 2002-11-28 Boehringer Ingelheim Vetmedica Gmbh PRRSV antigenic sites identifying peptide sequences of PRRS virus for use in vaccines or diagnostic assays
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
DK1183332T3 (da) 1999-04-22 2010-09-06 Us Agriculture Porcint Reproduktions- og Respirations Syndrom-vaccine baseret på isolere JA-142
US6740490B2 (en) 2001-01-29 2004-05-25 Kansas State University Research Foundation Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding
US6841364B2 (en) 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
BRPI0510928A (pt) 2004-06-18 2007-11-13 Univ Minnesota identificação de organismos viralmente infectados e vacinados
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
SI2281829T1 (sl) 2004-12-30 2015-03-31 Boehringer Ingelheim Vetmedica, Inc. PCV2 imunogeni sestavki za uporabo v postopku preprečevanja PCV2 infekcije
ATE462445T1 (de) 2005-01-13 2010-04-15 Boehringer Ingelheim Vetmed Prrs-impfstoffe
UA95778C2 (ru) 2005-06-24 2011-09-12 Риджентс Оф Зе Юниверсити Оф Миннесота Вирусы репродуктивно-респираторного синдрома свиней, их инфекционные клоны и мутанты и способы применения
JP5394750B2 (ja) 2005-12-29 2014-01-22 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド 多価ｐｃｖ２免疫原性組成物及び当該組成物を製造する方法
WO2008013918A2 (en) * 2006-07-26 2008-01-31 Myelin Repair Foundation, Inc. Cell cycle regulation and differentiation
US8202717B2 (en) 2007-01-12 2012-06-19 The Board Of Trustees Of The University Of Illinois Non-simian cells for growth of porcine reproductive and respiratory syndrome (PRRS) virus
US7666585B2 (en) * 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
AU2009218424A1 (en) * 2008-02-29 2009-09-03 Universiteit Gent Viral inactivation process
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
MY186535A (en) 2011-02-17 2021-07-26 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
WO2012110490A1 (en) 2011-02-17 2012-08-23 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
US9315781B2 (en) 2011-07-29 2016-04-19 Boehringer Ingelheim Vetmedica Gmbh Infectious CDNA clone of european PRRS virus and uses thereof
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
EP2968513A2 (de) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Prrs-virus, zusammensetzungen, impfstoff und verfahren zur verwendung
DK3083947T3 (da) 2013-12-20 2019-07-08 Boehringer Ingelheim Vetmedica Gmbh Prrs-virusvariant, cdna-klon af europæisk prrs-virus, samt anvendelser deraf
DK3344289T3 (da) 2015-08-31 2020-04-14 Boehringer Ingelheim Vetmedica Gmbh Pestivirusvacciner mod medfødt tremor
WO2017106079A1 (en) 2015-12-14 2017-06-22 Boehringer Ingelheim Vetmedica, Inc. Hybrid core feline vaccines
EP3953370A1 (de) 2019-04-04 2022-02-16 Boehringer Ingelheim Animal Health USA Inc. Impfstoffe gegen das porcine circovirus typ 3 (pcv3), ihre herstellung und verwendung
MX2023001024A (es) 2020-07-24 2023-02-15 Boehringer Ingelheim Animal Health Usa Inc Vacuna porcina combinada.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452902A (en) * 1981-11-19 1984-06-05 Labsystems Oy Method and equipment for the measurement of properties of a liquid
EP0587780B2 (de) * 1991-06-06 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits
CA2076744C (en) * 1991-08-26 2000-06-27 Danny W. Chladek Viral agent associated with mystery swine disease
WO1993003760A1 (en) * 1991-08-26 1993-03-04 James Edward Collins Sirs vaccine and diagnosis method
AU2696792A (en) * 1991-09-16 1993-04-27 David A Benfield Vaccine for mystery swine disease and method for diagnosis thereof
ES2165405T3 (es) * 1994-04-11 2002-03-16 Akzo Nobel Nv Cepas de vacuna europeas del virus del sindrome reproductor y respiratorio porcino (prrsv).

Also Published As

Publication number Publication date
WO1993007898A1 (en) 1993-04-29
ES2083764T5 (es) 2009-04-01
JPH07501049A (ja) 1995-02-02
EP0610250B1 (de) 1995-12-06
HUT69803A (en) 1995-09-28
US6033844A (en) 2000-03-07
EP0610250B2 (de) 2008-10-29
CA2121241A1 (en) 1993-04-29
DK0610250T4 (da) 2009-03-02
ATE131067T1 (de) 1995-12-15
ES2083764T3 (es) 1996-04-16
AU2684792A (en) 1993-05-21
HU220113B (hu) 2001-11-28
DK0610250T3 (da) 1996-04-09
CA2121241C (en) 2007-12-04
HU9401056D0 (en) 1994-07-28
DE69206631T2 (de) 1996-05-15
GR3019112T3 (en) 1996-05-31
EP0610250A1 (de) 1994-08-17

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: INTERVET INTERNATIONAL B. V., AN BOXMEER, NL

8366 Restricted maintained after opposition proceedings