KR970706300A - E형 간염 파키스탄형 균주의 재조합 단백질 및 이를 이용한 진단방법과 백신(recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines) - Google Patents

E형 간염 파키스탄형 균주의 재조합 단백질 및 이를 이용한 진단방법과 백신(recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines)

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Publication number
KR970706300A
KR970706300A KR1019970702198A KR19970702198A KR970706300A KR 970706300 A KR970706300 A KR 970706300A KR 1019970702198 A KR1019970702198 A KR 1019970702198A KR 19970702198 A KR19970702198 A KR 19970702198A KR 970706300 A KR970706300 A KR 970706300A
Authority
KR
South Korea
Prior art keywords
hepatitis
strain
vaccine
pakistani strain
pakistani
Prior art date
Application number
KR1019970702198A
Other languages
English (en)
Other versions
KR100359526B1 (ko
Inventor
세르게이 에이. 싸레브
수잔 유. 에머슨
로버트 에이치 퍼셀
Original Assignee
로버트 에이치 퍼셀
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/316,765 external-priority patent/US6706873B1/en
Application filed by 로버트 에이치 퍼셀 filed Critical 로버트 에이치 퍼셀
Publication of KR970706300A publication Critical patent/KR970706300A/ko
Application granted granted Critical
Publication of KR100359526B1 publication Critical patent/KR100359526B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/28011—Hepeviridae
    • C12N2770/28111—Hepevirus, e.g. hepatitis E virus
    • C12N2770/28122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/28011—Hepeviridae
    • C12N2770/28111—Hepevirus, e.g. hepatitis E virus
    • C12N2770/28123—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1019970702198A 1994-10-03 1995-10-03 E형간염파키스탄형균주의재조합단백질및이를이용한진단방법과백신 KR100359526B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/316,765 1994-10-03
US08/316,765 US6706873B1 (en) 1992-09-18 1994-10-03 Recombinant proteins of a pakistani strain of hepatitis E and their use in diagnostic methods and vaccines
PCT/US1995/013102 WO1996010580A2 (en) 1994-10-03 1995-10-03 Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines

Related Child Applications (2)

Application Number Title Priority Date Filing Date
KR1020007003415A Division KR100332602B1 (ko) 1992-09-18 1995-10-03 Ｅ형 간염 파키스탄형 균주의 재조합 단백질에 대한 항체
KR1020007010531A Division KR100318516B1 (ko) 1992-09-18 1995-10-03 Ｅ형 간염 파키스탄형 균주의 재조합 단백질 및 이를이용한 진단방법과 백신

Publications (2)

Publication Number Publication Date
KR970706300A true KR970706300A (ko) 1997-11-03
KR100359526B1 KR100359526B1 (ko) 2003-02-25

Family

ID=23230582

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019970702198A KR100359526B1 (ko) 1994-10-03 1995-10-03 E형간염파키스탄형균주의재조합단백질및이를이용한진단방법과백신

Country Status (9)

Country Link
EP (1) EP0784631B1 (ko)
JP (1) JP3889808B2 (ko)
KR (1) KR100359526B1 (ko)
CN (1) CN1148450C (ko)
AT (1) ATE518879T1 (ko)
AU (1) AU712901B2 (ko)
NO (1) NO326399B1 (ko)
NZ (1) NZ295056A (ko)
WO (1) WO1996010580A2 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054567A (en) * 1997-04-11 2000-04-25 The United States Of America As Represented By The Department Of Health And Human Services Recombinant proteins of a pakistani strain of hepatitis E and their use in diagnostic methods and vaccines
ATE346087T1 (de) 1997-07-18 2006-12-15 Us Health Hepatitis e-virus aus dem schwein und dessen verwendungen
US6458562B1 (en) 1998-04-09 2002-10-01 The United States Of America As Represented By The Secretary Of Health And Human Services Recombinant proteins of a Pakistani strain of hepatitis E and their use in diagnostic methods and vaccines
WO2001057073A2 (en) * 2000-02-07 2001-08-09 Department Of Science And Technology Infectious cdna clone of hepatitis e virus (hev) genome, its production and uses
CN101367869B (zh) 2000-09-30 2012-12-05 北京万泰生物药业股份有限公司 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗
US20040101820A1 (en) * 2001-06-25 2004-05-27 Kazuaki Takahashi Polynucleotide probe and primer originating in hepatitis e virus of japanese, chips having the same, kits having the same and method of detecting hepatits e virus using the same
CN100446813C (zh) * 2005-06-24 2008-12-31 东南大学 甲型肝炎-戊型肝炎联合疫苗及其制备方法
CN112225783B (zh) * 2020-09-16 2021-08-31 东莞市朋志生物科技有限公司 Hcv重组抗原及其突变体
CN114957411B (zh) * 2022-05-25 2023-08-18 徐州医科大学 一种正戊型肝病毒属基因c1型病毒orf2重组蛋白及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0662133B1 (en) * 1992-09-18 2009-11-18 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines
CA2179609A1 (en) * 1993-12-22 1995-06-29 Deborah A. Paul Monoclonal antibodies against hev orf-2 and methods for using same

Also Published As

Publication number Publication date
NO971529L (no) 1997-05-26
EP0784631A1 (en) 1997-07-23
AU3830995A (en) 1996-04-26
NZ295056A (en) 1999-06-29
JPH11500001A (ja) 1999-01-06
JP3889808B2 (ja) 2007-03-07
CN1168698A (zh) 1997-12-24
KR100359526B1 (ko) 2003-02-25
NO326399B1 (no) 2008-11-24
CN1148450C (zh) 2004-05-05
NO971529D0 (no) 1997-04-03
AU712901B2 (en) 1999-11-18
ATE518879T1 (de) 2011-08-15
WO1996010580A2 (en) 1996-04-11
WO1996010580A3 (en) 1996-05-23
EP0784631B1 (en) 2011-08-03

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