ATE518879T1 - Verfahren zur herstellung eines partiellen orf2 proteins des hepatitis e virus - Google Patents
Verfahren zur herstellung eines partiellen orf2 proteins des hepatitis e virusInfo
- Publication number
- ATE518879T1 ATE518879T1 AT95936312T AT95936312T ATE518879T1 AT E518879 T1 ATE518879 T1 AT E518879T1 AT 95936312 T AT95936312 T AT 95936312T AT 95936312 T AT95936312 T AT 95936312T AT E518879 T1 ATE518879 T1 AT E518879T1
- Authority
- AT
- Austria
- Prior art keywords
- hepatitis
- virus
- partial
- producing
- sar
- Prior art date
Links
- 241000724675 Hepatitis E virus Species 0.000 title abstract 2
- 101710159752 Poly(3-hydroxyalkanoate) polymerase subunit PhaE Proteins 0.000 title 1
- 101710130262 Probable Vpr-like protein Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 201000010284 hepatitis E Diseases 0.000 abstract 2
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/28011—Hepeviridae
- C12N2770/28111—Hepevirus, e.g. hepatitis E virus
- C12N2770/28122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/28011—Hepeviridae
- C12N2770/28111—Hepevirus, e.g. hepatitis E virus
- C12N2770/28123—Virus like particles [VLP]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/316,765 US6706873B1 (en) | 1992-09-18 | 1994-10-03 | Recombinant proteins of a pakistani strain of hepatitis E and their use in diagnostic methods and vaccines |
| PCT/US1995/013102 WO1996010580A2 (en) | 1994-10-03 | 1995-10-03 | Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518879T1 true ATE518879T1 (de) | 2011-08-15 |
Family
ID=23230582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95936312T ATE518879T1 (de) | 1994-10-03 | 1995-10-03 | Verfahren zur herstellung eines partiellen orf2 proteins des hepatitis e virus |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0784631B1 (de) |
| JP (1) | JP3889808B2 (de) |
| KR (1) | KR100359526B1 (de) |
| CN (1) | CN1148450C (de) |
| AT (1) | ATE518879T1 (de) |
| AU (1) | AU712901B2 (de) |
| NO (1) | NO326399B1 (de) |
| NZ (1) | NZ295056A (de) |
| WO (1) | WO1996010580A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6054567A (en) * | 1997-04-11 | 2000-04-25 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant proteins of a pakistani strain of hepatitis E and their use in diagnostic methods and vaccines |
| EP1000168B1 (de) * | 1997-07-18 | 2006-11-22 | The United States of America, as represented by the Secretary Department of Health and Human Services | Hepatitis e-virus aus dem schwein und dessen verwendungen |
| US6458562B1 (en) | 1998-04-09 | 2002-10-01 | The United States Of America As Represented By The Secretary Of Health And Human Services | Recombinant proteins of a Pakistani strain of hepatitis E and their use in diagnostic methods and vaccines |
| EP1169341A1 (de) * | 2000-02-07 | 2002-01-09 | Department of Science and Technology | Infektiöser cdna-klon des hepatitis e virus (hev) genom, dessen herstellung und verwendung |
| CN1345775A (zh) | 2000-09-30 | 2002-04-24 | 养生堂有限公司 | 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 |
| WO2003000887A1 (en) * | 2001-06-25 | 2003-01-03 | Kabushiki Kaisha Toshiba | Polynucleotide probe and primer originating in hepatitis e virus of japanese, chips having the same, kits having the same and method of detecting hepatitis e virus using the same |
| CN100446813C (zh) * | 2005-06-24 | 2008-12-31 | 东南大学 | 甲型肝炎-戊型肝炎联合疫苗及其制备方法 |
| CN112225783B (zh) * | 2020-09-16 | 2021-08-31 | 东莞市朋志生物科技有限公司 | Hcv重组抗原及其突变体 |
| CN114957411B (zh) * | 2022-05-25 | 2023-08-18 | 徐州医科大学 | 一种正戊型肝病毒属基因c1型病毒orf2重组蛋白及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994006913A2 (en) * | 1992-09-18 | 1994-03-31 | The Government Of The United States Of America As Represented By The Secretary, Department Of Healthand Human Services | Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines |
| AU1437695A (en) * | 1993-12-22 | 1995-07-10 | Abbott Laboratories | Monoclonal antibodies against hev orf-2 and methods for using same |
-
1995
- 1995-10-03 JP JP51217096A patent/JP3889808B2/ja not_active Expired - Fee Related
- 1995-10-03 KR KR1019970702198A patent/KR100359526B1/ko not_active IP Right Cessation
- 1995-10-03 AU AU38309/95A patent/AU712901B2/en not_active Ceased
- 1995-10-03 CN CNB951965484A patent/CN1148450C/zh not_active Expired - Lifetime
- 1995-10-03 WO PCT/US1995/013102 patent/WO1996010580A2/en not_active Application Discontinuation
- 1995-10-03 EP EP95936312A patent/EP0784631B1/de not_active Expired - Lifetime
- 1995-10-03 NZ NZ295056A patent/NZ295056A/xx not_active IP Right Cessation
- 1995-10-03 AT AT95936312T patent/ATE518879T1/de not_active IP Right Cessation
-
1997
- 1997-04-03 NO NO19971529A patent/NO326399B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1168698A (zh) | 1997-12-24 |
| KR970706300A (ko) | 1997-11-03 |
| JP3889808B2 (ja) | 2007-03-07 |
| AU3830995A (en) | 1996-04-26 |
| NZ295056A (en) | 1999-06-29 |
| NO971529L (no) | 1997-05-26 |
| WO1996010580A2 (en) | 1996-04-11 |
| WO1996010580A3 (en) | 1996-05-23 |
| NO326399B1 (no) | 2008-11-24 |
| JPH11500001A (ja) | 1999-01-06 |
| AU712901B2 (en) | 1999-11-18 |
| NO971529D0 (no) | 1997-04-03 |
| EP0784631B1 (de) | 2011-08-03 |
| CN1148450C (zh) | 2004-05-05 |
| KR100359526B1 (ko) | 2003-02-25 |
| EP0784631A1 (de) | 1997-07-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO1994006913A3 (en) | Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines | |
| Purcell | The hepatitis C virus: overview | |
| AU738585B2 (en) | Synthesis and purification of hepatitis C virus-like particles | |
| Forns et al. | DNA immunization of mice and macaques with plasmids encoding hepatitis C virus envelope E2 protein expressed intracellularly and on the cell surface | |
| DK0527815T3 (da) | Hepatitis C-virus-epitop | |
| DK0610250T4 (da) | Vaccine med porcint reproduktivt respiratorisk syndrom (PRRS) og diagnose heraf | |
| ATE17320T1 (de) | Impfstoff, therapie gegen nicht-a nicht-b virale hepatitis und verfahren zur herstellung desselben. | |
| WO1993014208A3 (en) | Hepatitis e virus vaccine and method | |
| ATE518879T1 (de) | Verfahren zur herstellung eines partiellen orf2 proteins des hepatitis e virus | |
| DE60039715D1 (de) | Hcv-impfstoff zusammensetzungen | |
| DE69534617D1 (en) | Hepatitis b-impfstoff | |
| ATE267256T1 (de) | Hepatis e-virus antigene und dessen verwendungen | |
| ATE189683T1 (de) | Hcv peptidantigene und verfahren zur bestimmung von hcv | |
| CA1292690C (en) | Vaccine comprising an immunogenic protein and, as an adjuvant, a substantially non-immunogenic sequentially homologous peptide | |
| CA2286399A1 (en) | Recombinant proteins of a pakistani strain of hepatitis e and their use in diagnostic methods and vaccines | |
| NZ309172A (en) | Neutralizing conformational epitopes of chicken anemia virus | |
| WO2002089733A3 (en) | Recombinant orf2 proteins of the swine hepatitis e virus and their use as a vaccine and as a diagnostic reagent for medical and veterinary applications | |
| DE542949T1 (de) | Hepatitis a virusstamm, verfahren zur isolierung eines hepatitis a virusstammes und vakzine hepatitis a. | |
| Inchauspe | Protection and defence mechanisms in HCV infection | |
| Chen et al. | Identification of the antigenic components of Hantaan virus reacting with rabbit antisera and sera from patients with hemorrhagic fever with renal syndrome | |
| MX9709851A (es) | Epitopes neutralizadores conformacionales del virus de la anemia de pollo. | |
| HUT53809A (en) | Process for producing inactivated, adiuvated vaccine against rabbit haemorrhagic disease (rhd) caused by virus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |