CN101367869B - 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 - Google Patents
用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 Download PDFInfo
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- CN101367869B CN101367869B CN2008100851107A CN200810085110A CN101367869B CN 101367869 B CN101367869 B CN 101367869B CN 2008100851107 A CN2008100851107 A CN 2008100851107A CN 200810085110 A CN200810085110 A CN 200810085110A CN 101367869 B CN101367869 B CN 101367869B
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- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- A61K2039/6031—Proteins
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- C12N2760/00011—Details
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Abstract
Description
0 | 1w | 2w | 3w | 4w | 5w | 6w | |
1# | - | - | 103 | 104 | 104 | 105 | 105 |
2# | - | - | - | 102 | 103 | 104 | 104 |
3# | - | - | 103 | 104 | 104 | 104 | 104 |
Claims (7)
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CN00130634A CN1345775A (zh) | 2000-09-30 | 2000-09-30 | 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 |
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CN00130634A Division CN1345775A (zh) | 2000-09-30 | 2000-09-30 | 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 |
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CN101367869A CN101367869A (zh) | 2009-02-18 |
CN101367869B true CN101367869B (zh) | 2012-12-05 |
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CN2008100851107A Expired - Lifetime CN101367869B (zh) | 2000-09-30 | 2000-09-30 | 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 |
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CN00130634A Pending CN1345775A (zh) | 2000-09-30 | 2000-09-30 | 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 |
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EP (2) | EP2298793A3 (zh) |
JP (3) | JP5681337B2 (zh) |
KR (2) | KR100927221B1 (zh) |
CN (2) | CN1345775A (zh) |
AU (1) | AU2002220460A1 (zh) |
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WO (1) | WO2002040681A1 (zh) |
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CN1345775A (zh) * | 2000-09-30 | 2002-04-24 | 养生堂有限公司 | 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 |
BRPI0214188B8 (pt) | 2001-11-08 | 2021-05-25 | Beijing Wantai Biological Pharmacy Entpr Co Ltd | anticorpo ou fragmento do mesmo, molécula de ácido nucléico, uso do anticorpo monoclonal ou fragmento do mesmo, kit de diagnóstico, composição farmacêutica, vetor de expressão recombinante, célula hospedeira transformada com o vetor de expressão recombinante e método para detectar o antígeno do vírus da hepatite e ou o anticorpo contra o vírus da hepatite e em uma amostra |
CN1850855B (zh) * | 2006-05-26 | 2012-08-29 | 厦门大学 | 用于免疫或制备单克隆抗体的方法和组合物 |
JP5869885B2 (ja) * | 2009-02-27 | 2016-02-24 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | E型肝炎ウイルス様粒子を用いた多抗原送達系 |
US8906863B2 (en) | 2009-02-27 | 2014-12-09 | The Regents Of The University Of California | Proteolysis-resistant capsid of chimeric hepatitis E virus as an oral delivery vector |
US8906862B2 (en) | 2009-02-27 | 2014-12-09 | The Regents Of The University Of California | Multiple antigen delivery system using hepatitis E virus-like particle |
WO2012028161A1 (en) * | 2010-08-31 | 2012-03-08 | Abb Technology Ag | Method for debugging of process or manufacturing plant solutions comprising multiple sub-systems |
CN102453748A (zh) * | 2010-10-18 | 2012-05-16 | 北京雅康博生物科技有限公司 | 用于荧光定量pcr定量检测的质粒标准品 |
CN102565410B (zh) * | 2012-01-12 | 2014-08-06 | 吉林大学 | 一种梅花鹿朊蛋白免疫学检测方法 |
EP2846829B1 (en) * | 2012-05-09 | 2021-09-08 | Bharat Biotech International Limited | Vaccine combinations |
CN104031144B (zh) * | 2013-03-05 | 2017-08-25 | 厦门大学 | 特异结合戊型肝炎病毒3、4型的抗体及其用途 |
CN104789534B (zh) * | 2015-04-10 | 2017-10-17 | 浙江中医药大学 | 一种杂交瘤、单克隆抗体及其用途 |
FR3044312B1 (fr) * | 2015-11-30 | 2017-12-08 | Biomerieux Sa | Polypeptides mutes de hev et leur utilisation pour le dosage d'anticorps anti-hev |
CN109195624B (zh) * | 2016-05-25 | 2022-02-22 | 英特维特国际股份有限公司 | Hev疫苗 |
KR101924093B1 (ko) | 2017-04-18 | 2018-11-30 | 건국대학교 산학협력단 | E형 간염 바이러스 유전자형 3 및 4 진단용 프라이머 세트 및 이를 이용한 진단 방법 |
CN110501505B (zh) * | 2018-05-18 | 2022-06-10 | 中国兽医药品监察所 | 小反刍兽疫诊断试剂盒 |
WO2020011755A1 (en) * | 2018-07-10 | 2020-01-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies having specificity for the orf2i protein of hepatitis e virus and uses thereof for diagnostic purposes |
ES2970072T3 (es) * | 2018-07-10 | 2024-05-24 | Inst Nat Sante Rech Med | Anticuerpos que tienen especificidad por la proteína ORF2i del virus de la hepatitis E y usos de los mismos con fines de diagnóstico |
CN109942702B (zh) * | 2019-03-20 | 2019-11-08 | 南京医科大学 | 一种人鼠嵌合抗HEV全分子IgG及其应用 |
JP7259622B2 (ja) | 2019-07-29 | 2023-04-18 | パナソニックホールディングス株式会社 | 冷却システム及びその運転方法 |
JPWO2023282243A1 (zh) | 2021-07-06 | 2023-01-12 |
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NZ219515A (en) | 1987-02-10 | 1989-09-27 | Wellcome Found | Fusion proteins comprising influenza virus ha and a nonnatural antigenic epitope |
US5110730A (en) * | 1987-03-31 | 1992-05-05 | The Scripps Research Institute | Human tissue factor related DNA segments |
US5885768A (en) | 1988-06-17 | 1999-03-23 | The United States Of America As Represented By The Department Of Health And Human Services | Hepatitis E virus peptide antigen and antibodies |
US6214970B1 (en) | 1988-06-17 | 2001-04-10 | Genelabs Technologies, Inc. | Hepatitis E virus antigens and uses therefor |
US5714374A (en) * | 1990-09-12 | 1998-02-03 | Rutgers University | Chimeric rhinoviruses |
US5563032A (en) * | 1992-10-21 | 1996-10-08 | The United States Of America As Represented By The Department Of Health And Human Services | Mosaic polypeptide and methods for detecting the hepatitis E virus |
JPH09507025A (ja) | 1993-12-22 | 1997-07-15 | アボツト・ラボラトリーズ | HEV orf−2に対するモノクローナル抗体及びそれらを使用する方法 |
NZ295056A (en) * | 1994-10-03 | 1999-06-29 | Us Health | Hepatitis virus e strain, recombinant proteins thereof, use in diagnostic methods and vaccines |
AUPN443995A0 (en) | 1995-07-27 | 1995-08-17 | Csl Limited | Papillomavirus polyprotein |
US6054567A (en) * | 1997-04-11 | 2000-04-25 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant proteins of a pakistani strain of hepatitis E and their use in diagnostic methods and vaccines |
DE19830896A1 (de) * | 1998-07-10 | 2000-06-08 | Mivatec Gmbh | Fotoplott-Verfahren zur hochenergetischen Aufzeichnung eines computergespeicherten Rasterbildes auf einen lichtempfindlichen Aufzeichnungsträger |
US6045567A (en) * | 1999-02-23 | 2000-04-04 | Lifescan Inc. | Lancing device causing reduced pain |
CA2283538A1 (en) * | 1999-09-30 | 2001-03-30 | Mun Hon Ng | New hev antigenic peptide and methods |
CN1345775A (zh) * | 2000-09-30 | 2002-04-24 | 养生堂有限公司 | 用于预防、诊断及治疗戊型肝炎病毒的多肽,及它们作为诊断试剂和疫苗 |
-
2000
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- 2001-09-30 JP JP2002542994A patent/JP5681337B2/ja not_active Expired - Lifetime
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2011
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2014
- 2014-02-12 JP JP2014024629A patent/JP2014138593A/ja active Pending
Non-Patent Citations (1)
Title |
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YE Khudyakov,etc..Immunodominant Antigenic Regions in a Structural Protein ofthe Hepatitis E Virus.Virology198.1994,198390-393. * |
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CN101367869A (zh) | 2009-02-18 |
JP2011201881A (ja) | 2011-10-13 |
EP1331271A4 (en) | 2005-04-06 |
KR100927221B1 (ko) | 2009-11-16 |
WO2002040681A1 (fr) | 2002-05-23 |
KR20030048052A (ko) | 2003-06-18 |
US20100143410A1 (en) | 2010-06-10 |
US8715695B2 (en) | 2014-05-06 |
EP1331271A1 (en) | 2003-07-30 |
US20100150962A1 (en) | 2010-06-17 |
EP2298793A3 (en) | 2011-06-29 |
JP5681337B2 (ja) | 2015-03-04 |
JP2004525613A (ja) | 2004-08-26 |
US20040052813A1 (en) | 2004-03-18 |
JP5829830B2 (ja) | 2015-12-09 |
KR20090088429A (ko) | 2009-08-19 |
EP1331271B1 (en) | 2014-03-19 |
US7615228B2 (en) | 2009-11-10 |
JP2014138593A (ja) | 2014-07-31 |
BRPI0114510B8 (pt) | 2021-05-25 |
EP2298793A2 (en) | 2011-03-23 |
CN1345775A (zh) | 2002-04-24 |
US8524868B2 (en) | 2013-09-03 |
BR0114510A (pt) | 2004-02-17 |
MXPA03002751A (es) | 2004-05-04 |
AU2002220460A1 (en) | 2002-05-27 |
BRPI0114510B1 (pt) | 2019-09-03 |
KR101121754B1 (ko) | 2012-03-23 |
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