ES2078187B1 - Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes. - Google Patents

Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes.

Info

Publication number
ES2078187B1
ES2078187B1 ES09401027A ES9401027A ES2078187B1 ES 2078187 B1 ES2078187 B1 ES 2078187B1 ES 09401027 A ES09401027 A ES 09401027A ES 9401027 A ES9401027 A ES 9401027A ES 2078187 B1 ES2078187 B1 ES 2078187B1
Authority
ES
Spain
Prior art keywords
proteins
recombinant proteins
diagnostic kits
recrs
combinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES09401027A
Other languages
English (en)
Other versions
ES2078187A1 (es
Inventor
Duran Juan Plana
Alvarez Jose Ignacio Casal
Sanchez M Isabel Climent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zoetis Belgium SA
Original Assignee
Cynamid Iberica S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cynamid Iberica S A filed Critical Cynamid Iberica S A
Priority to ES09401027A priority Critical patent/ES2078187B1/es
Priority to ES09500815A priority patent/ES2085837B1/es
Priority to DK053595A priority patent/DK53595A/da
Priority to GB9509392A priority patent/GB2289279B/en
Priority to CA002167080A priority patent/CA2167080C/en
Priority to AT95917990T priority patent/ATE280829T1/de
Priority to DK95917990T priority patent/DK0717108T3/da
Priority to JP7529381A priority patent/JPH09500544A/ja
Priority to PT95917990T priority patent/PT717108E/pt
Priority to EP95917990A priority patent/EP0717108B1/en
Priority to DE69533690T priority patent/DE69533690T2/de
Priority to SI9530711T priority patent/SI0717108T1/xx
Priority to IT95TO000367A priority patent/IT1277996B1/it
Priority to AU24094/95A priority patent/AU699385B2/en
Priority to PCT/ES1995/000053 priority patent/WO1995031550A1/es
Priority to EP04076580A priority patent/EP1469076A3/en
Priority to MYPI95001259A priority patent/MY126289A/en
Priority to DE19549523A priority patent/DE19549523C2/de
Priority to DE19517773A priority patent/DE19517773A1/de
Priority to NL1000365A priority patent/NL1000365C2/xx
Priority to FR9505716A priority patent/FR2719845B1/fr
Priority to TW084112185A priority patent/TW450977B/zh
Publication of ES2078187A1 publication Critical patent/ES2078187A1/es
Priority to US08/578,614 priority patent/US5888513A/en
Application granted granted Critical
Publication of ES2078187B1 publication Critical patent/ES2078187B1/es
Priority to HK98115793A priority patent/HK1014546A1/xx
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROTEINAS RECOMBINANTES DE PRRS, KITS DE DIAGNOSTICO Y VACUNAS QUE CONTIENEN DICHAS PROTEINAS RECOMBINANTES. SE HAN PRODUCIDO PROTEINAS RECOMBINANTES DEL VIRUS CAUSAL DEL SINDROME RESPIRATORIO Y REPRODUCTIVO PORCINO (PRRS), CORRESPONDIENTES A LAS ORFS 2 A 7 DEL PRRSV AISLADO EN ESPAÑA, (PRRS-OLOT), EN UN SISTEMA DE EXPRESION DE BACULOVIRUS RECOMBINANTES MULTIPLICADOS EN UN CULTIVO DE CELULAS DE UN HUESPED PERMISIVO. ESTAS PROTEINAS RECOMBINANTES SON ADECUADAS PARA FORMULAR VACUNAS CAPACES DE PROTEGER EFICAZMENTE AL GANADO PORCINO DEL PRRS ASI COMO PARA PREPARAR KITS DE DIAGNOSTICO ADECUADOS PARA DETECTAR TANTO LA PRESENCIA DE ANTICUERPOS QUE RECONOCEN AL PRRSV COMO LA PRESENCIA DE PRRSV EN UNA MUESTRA BIOLOGICA PORCINA. ESTA INVENCION TIENE INTERES EN VETERINARIA.
ES09401027A 1994-05-13 1994-05-13 Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes. Expired - Fee Related ES2078187B1 (es)

Priority Applications (24)

Application Number Priority Date Filing Date Title
ES09401027A ES2078187B1 (es) 1994-05-13 1994-05-13 Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes.
ES09500815A ES2085837B1 (es) 1994-05-13 1995-04-27 Proteinas recombinantes de prrsv, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes
GB9509392A GB2289279B (en) 1994-05-13 1995-05-09 Diagnostic kits and vaccines containing recombinant PRRSV proteins
DK053595A DK53595A (da) 1994-05-13 1995-05-09 Rekombinante PRRSV-proteiner, diagnostiske kits og vaccine indeholdende sådanne rekombinante PRRSV-proteiner
AU24094/95A AU699385B2 (en) 1994-05-13 1995-05-10 Recombinant prrsv proteins, diagnostic kits and vaccines containing such recombinant prrsv proteins
DK95917990T DK0717108T3 (da) 1994-05-13 1995-05-10 Rekombinante PRRS-proteiner, diagnostiske kits og vacciner indeholdende de rekombinante proteiner
JP7529381A JPH09500544A (ja) 1994-05-13 1995-05-10 組換えｐｒｒｓｖタンパク、該組換えｐｒｒｓｖタンパクを含有する診断キットおよびワクチン
PT95917990T PT717108E (pt) 1994-05-13 1995-05-10 Proteinas pprs recombinantes, estojos (''kits'') de diagnostico e vacinas contendo as referidas proteinas recombinantes
EP95917990A EP0717108B1 (en) 1994-05-13 1995-05-10 Recombinant prrs proteins, diagnostic kits and vaccines containing said recombinant proteins
DE69533690T DE69533690T2 (de) 1994-05-13 1995-05-10 Recombinante prrs viren -proteine und dieselben diagnosesätze und impfstoffe enthaltenden
SI9530711T SI0717108T1 (en) 1994-05-13 1995-05-10 Recombinant prrs proteins, diagnostic kits and vaccines containing said recombinant proteins
IT95TO000367A IT1277996B1 (it) 1994-05-13 1995-05-10 Proteine di prrsv ricombinanti, corredi diagnostici e vaccini contenenti tali proteine di prrsv ricombinanti.
CA002167080A CA2167080C (en) 1994-05-13 1995-05-10 Prrsv recombinant proteins, diagnostic kits and vaccines containing prrs recombinant proteins
PCT/ES1995/000053 WO1995031550A1 (es) 1994-05-13 1995-05-10 Proteinas recombinantes de prrsv, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes
EP04076580A EP1469076A3 (en) 1994-05-13 1995-05-10 Recombinant PRRS proteins, diagnostic kits and vaccines containing said recombinant proteins
AT95917990T ATE280829T1 (de) 1994-05-13 1995-05-10 Recombinante prrs viren -proteine und dieselben diagnosesätze und impfstoffe enthaltenden
MYPI95001259A MY126289A (en) 1994-05-13 1995-05-12 Diagnostic kits and vaccines containing recombinant prrsv proteins
DE19549523A DE19549523C2 (de) 1994-05-13 1995-05-15 Diagnostik-Kits, die rekombinante PRRSV Proteine enthalten
DE19517773A DE19517773A1 (de) 1994-05-13 1995-05-15 Rekombinante PRRSV-Proteine, Diagnostik-Kits und solche rekombinanten PRRSV-Proteine enthaltenden Vakzinen
NL1000365A NL1000365C2 (nl) 1994-05-13 1995-05-15 Recombinante PRRSV-eiwitten, diagnostische kits en vaccins die dergelijke recombinante PRRSV-eiwitten bevatten.
FR9505716A FR2719845B1 (fr) 1994-05-13 1995-05-15 Protéines PRRSV recombinantes, kits de diagnostic et vaccins contenant ces protéines PRRSV recombinantes.
TW084112185A TW450977B (en) 1994-05-13 1995-11-15 Recombinant PRRSV proteins, diagnostic kits and vaccines containing such recombinant PRRSV proteins
US08/578,614 US5888513A (en) 1994-05-13 1996-04-08 Recombinant PRRSV proteins, diagnostic kits and vaccines containing such recombinant PRRSV proteins
HK98115793A HK1014546A1 (en) 1994-05-13 1998-12-28 Recombinant prrs proteins, diagnostic kits and vaccines containing said recombinant proteins.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09401027A ES2078187B1 (es) 1994-05-13 1994-05-13 Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes.

Publications (2)

Publication Number Publication Date
ES2078187A1 ES2078187A1 (es) 1995-12-01
ES2078187B1 true ES2078187B1 (es) 1996-07-16

Family

ID=8286221

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09401027A Expired - Fee Related ES2078187B1 (es) 1994-05-13 1994-05-13 Proteinas recombinantes de prrs, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes.
ES09500815A Expired - Fee Related ES2085837B1 (es) 1994-05-13 1995-04-27 Proteinas recombinantes de prrsv, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES09500815A Expired - Fee Related ES2085837B1 (es) 1994-05-13 1995-04-27 Proteinas recombinantes de prrsv, kits de diagnostico y vacunas que contienen dichas proteinas recombinantes

Country Status (5)

Country Link
EP (1) EP1469076A3 (es)
DE (1) DE19549523C2 (es)
ES (2) ES2078187B1 (es)
MY (1) MY126289A (es)
SI (1) SI0717108T1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1792996A1 (en) * 2005-12-01 2007-06-06 Consejo Superior de Investigaciones Cientificas Nucleic acid sequences encoding vaccines against Porcine reproductive and respiratory syndrome virus (PRRSV)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA27788C2 (uk) * 1991-06-06 2000-10-16 Стіхтінг Сентрал Діргенескюндіг Інстітют Композиція, що містить виділений фактор лелістада, вакцинна композиція для вакцинації тварин (варіанти), діагностичний набір для виявлення антитіла
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.

Also Published As

Publication number Publication date
SI0717108T1 (en) 2005-02-28
ES2085837B1 (es) 1997-07-01
MY126289A (en) 2006-09-29
EP1469076A3 (en) 2004-12-08
ES2078187A1 (es) 1995-12-01
DE19549523C2 (de) 2000-11-02
EP1469076A2 (en) 2004-10-20
ES2085837A1 (es) 1996-06-01

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