ES8505819A1 - Un procedimiento de una vacuna capaz de inducir la produccion de anticuerpos de reaccion con mas de una cepa de virus dela influenza. - Google Patents

Un procedimiento de una vacuna capaz de inducir la produccion de anticuerpos de reaccion con mas de una cepa de virus dela influenza.

Info

Publication number
ES8505819A1
ES8505819A1 ES525088A ES525088A ES8505819A1 ES 8505819 A1 ES8505819 A1 ES 8505819A1 ES 525088 A ES525088 A ES 525088A ES 525088 A ES525088 A ES 525088A ES 8505819 A1 ES8505819 A1 ES 8505819A1
Authority
ES
Spain
Prior art keywords
antisera
broad spectrum
spectrum influenza
influenza
differing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525088A
Other languages
English (en)
Other versions
ES525088A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of ES8505819A1 publication Critical patent/ES8505819A1/es
Publication of ES525088A0 publication Critical patent/ES525088A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA VACUNA CAPAZ DE INDUCIR LA PRODUCCION DE ANTICUERPOS QUE REACCIONAN CON MAS DE UNA CEPA DEL VIRUS DE LA INFLUENZA.COMPRENDE LAS SIGUIENTES ETAPAS: PRIMERA, SE PREPARA UNA RESINA INSOLUBLE QUE CONTIENE UNA PLURALIDAD DE GRUPOS CLOROMETILO Y SE LA ESTERIFICA BOC(MEOBZL)0CYS-OH; SEGUNDA, SE SEPARA EL GRUPO BOC PARA OBTENER UN GRUPO AMINO LIBRE SOBRE LE RESTO CYS; TERCERA, SE HACE REACCIONAR LA AMINA LIBRE CON UN EXCESO DE OTRO AMINOACIDO QUE CONTENGA UN GRUPO CARBOXILO LIBRE; Y POR ULTIMO, SE SINTETIZA UN PEPTIDO PROTEGIDO DE UNA SECUENCIA DETERMINADA Y SE LE HACE REACCIONAR CON UN PORTADOR PARA FORMAR UN CONJUGADO, EL CUAL SE DISUELVE EN UN DILUYENTE FISIOLOGICO PARA FORMAR LA VACUNA.
ES525088A 1982-08-23 1983-08-22 Un procedimiento de una vacuna capaz de inducir la produccion de anticuerpos de reaccion con mas de una cepa de virus dela influenza. Granted ES525088A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41045582A 1982-08-23 1982-08-23

Publications (2)

Publication Number Publication Date
ES8505819A1 true ES8505819A1 (es) 1985-06-16
ES525088A0 ES525088A0 (es) 1985-06-16

Family

ID=23624803

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525088A Granted ES525088A0 (es) 1982-08-23 1983-08-22 Un procedimiento de una vacuna capaz de inducir la produccion de anticuerpos de reaccion con mas de una cepa de virus dela influenza.

Country Status (16)

Country Link
EP (1) EP0116629A4 (es)
JP (1) JPS59501714A (es)
KR (1) KR840006198A (es)
AU (1) AU570929B2 (es)
DK (1) DK203684D0 (es)
ES (1) ES525088A0 (es)
FI (1) FI841583A (es)
GR (1) GR78931B (es)
IL (1) IL69556A (es)
IT (1) IT1168636B (es)
NO (1) NO161002C (es)
NZ (2) NZ205341A (es)
PH (1) PH18872A (es)
PT (1) PT77230B (es)
WO (1) WO1984000687A1 (es)
ZA (1) ZA836080B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR241713A1 (es) * 1984-08-30 1992-11-30 Smithkline Beckman Corp Molecula de dna con una secuencia de bases que codifica la proteina c13 y preparacion de vacunas contra la gripe.
US5866363A (en) 1985-08-28 1999-02-02 Pieczenik; George Method and means for sorting and identifying biological information
AU4948890A (en) * 1989-01-12 1990-08-13 Blood Center Of Southeastern Wisconsin, The Peptide-mediated modulation of t-cell recognition as a means of affecting immune responses
EP0621339B1 (en) * 1992-09-17 2001-10-24 Takara Shuzo Co. Ltd. Immunogenic human influenza A virus haemagglutinin polypeptides
JP2996864B2 (ja) * 1994-03-30 2000-01-11 寳酒造株式会社 抗体可変領域ｄｎａ
US8148085B2 (en) 2006-05-15 2012-04-03 Sea Lane Biotechnologies, Llc Donor specific antibody libraries
AU2007249160B2 (en) * 2006-05-15 2013-09-12 I2 Pharmaceuticals, Inc. Neutralizing antibodies to influenza viruses
PL2059532T3 (pl) * 2006-09-07 2013-05-31 Crucell Holland Bv Ludzkie cząsteczki wiążące zdolne do neutralizowania wirusa grypy H5N1 i ich zastosowania
ITTO20070066A1 (it) 2007-01-30 2008-07-31 Pomona Biotechnologies Llc Anticorpi monoclonali anti-idiotipo mimotopi dell'antigene gp 120 di hiv
JP5779350B2 (ja) 2007-03-27 2015-09-16 シー レーン バイオテクノロジーズ， エルエルシー 抗体代替軽鎖配列を含む構築物およびライブラリー
ITTO20080204A1 (it) 2008-03-17 2009-09-18 Pomona Biotechnologies Llc Anticorpi monoclonali atti a reagire con una pluralita di sottotipi del virus influenzale a
JP2011516423A (ja) 2008-03-28 2011-05-26 シー レーン バイオテクノロジーズ， エルエルシー ウイルス抗原に対する中和分子
ITTO20080398A1 (it) 2008-05-27 2009-11-28 Pomona Biotechnologies Llc Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1
ITTO20080964A1 (it) 2008-12-22 2010-06-23 Natimab Therapeutics S R L Anticorpo monoclonale anti-hcv come medicamento per il trattamento terapeutico e la prevenzione di infezioni da hcv
US8975378B2 (en) 2008-12-25 2015-03-10 Osaka University Human anti-human influenza virus antibody
CA2787099A1 (en) 2009-03-30 2010-10-14 Anice C. Lowen Influenza virus hemagglutinin polypeptides containing stem domains, vaccines and uses thereof
US20120128671A1 (en) * 2009-05-13 2012-05-24 Lawrence Horowitz Neutralizing molecules to influenza viruses
AU2010254136B2 (en) 2009-05-26 2016-09-29 Mount Sinai School Of Medicine Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
IT1395961B1 (it) 2009-06-01 2012-11-02 Pomona Biotechnologies Llc Anticorpi monoclonali come medicamento per il trattamento terapeutico e/o profilattico delle infezioni da virus influenzale a (h1n1) di origine suina (s-oiv)
US9701723B2 (en) * 2010-02-18 2017-07-11 Icahn School Of Medicine At Mount Sinai Vaccines for use in the prophylaxis and treatment of influenza virus disease
AU2011235220B2 (en) 2010-03-30 2016-03-10 Mount Sinai School Of Medicine Influenza virus vaccines and uses thereof
EP2736928B1 (en) 2011-07-28 2019-01-09 i2 Pharmaceuticals, Inc. Sur-binding proteins against erbb3
MX2014003308A (es) 2011-09-20 2015-03-09 Sinai School Medicine Vacunas para el virus de la influenza y usos de las mismas.
EP2793940B1 (en) 2011-12-22 2018-11-14 i2 Pharmaceuticals, Inc. Surrogate binding proteins
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
CN108641002A (zh) 2012-12-18 2018-10-12 西奈山伊坎医学院 流感病毒疫苗及其用途
WO2014159960A1 (en) 2013-03-14 2014-10-02 Icahn School Of Medicine At Mount Sinai Antibodies against influenza virus hemagglutinin and uses thereof
US10736956B2 (en) 2015-01-23 2020-08-11 Icahn School Of Medicine At Mount Sinai Influenza virus vaccination regimens
US10513553B2 (en) 2015-11-13 2019-12-24 Visterra, Inc. Compositions and methods for treating and preventing influenza
JP7237344B2 (ja) 2016-06-15 2023-03-13 アイカーン スクール オブ メディシン アット マウント サイナイ インフルエンザウイルス血球凝集素タンパク質及びその使用
CA3058652A1 (en) 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof
AU2020248404A1 (en) 2019-03-25 2021-09-30 Visterra, Inc. Compositions and methods for treating and preventing influenza

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL63224A (en) * 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom

Also Published As

Publication number Publication date
EP0116629A4 (en) 1987-06-29
IT8348868A0 (it) 1983-08-22
KR840006198A (ko) 1984-11-22
AU1947183A (en) 1984-03-07
NO161002C (no) 1989-06-21
NO161002B (no) 1989-03-13
DK203684A (da) 1984-04-18
EP0116629A1 (en) 1984-08-29
IL69556A0 (en) 1983-11-30
ZA836080B (en) 1984-04-25
IT1168636B (it) 1987-05-20
NZ220612A (en) 1988-07-28
WO1984000687A1 (en) 1984-03-01
FI841583A0 (fi) 1984-04-19
NZ205341A (en) 1988-07-28
DK203684D0 (da) 1984-04-18
NO841540L (no) 1984-04-17
JPS59501714A (ja) 1984-10-11
PT77230B (en) 1986-02-04
GR78931B (es) 1984-10-02
IL69556A (en) 1988-05-31
PT77230A (en) 1983-09-01
ES525088A0 (es) 1985-06-16
PH18872A (en) 1985-10-21
AU570929B2 (en) 1988-03-31
FI841583A (fi) 1984-04-19

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