ES2013801A6 - Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales. - Google Patents

Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.

Info

Publication number
ES2013801A6
ES2013801A6 ES8803062A ES8803062A ES2013801A6 ES 2013801 A6 ES2013801 A6 ES 2013801A6 ES 8803062 A ES8803062 A ES 8803062A ES 8803062 A ES8803062 A ES 8803062A ES 2013801 A6 ES2013801 A6 ES 2013801A6
Authority
ES
Spain
Prior art keywords
same
benzopyran
derivative
salt
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8803062A
Other languages
English (en)
Spanish (es)
Inventor
Shuntaro Takano
Chosaku Yoshida
Takahiro Inaba
Keiichi Tanaka
Ryuko Takeno
Hideyoshi Nagaki
Tomoya Shimotori
Shinji Makino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of ES2013801A6 publication Critical patent/ES2013801A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C07D311/54—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 substituted in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
ES8803062A 1987-10-08 1988-10-07 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales. Expired - Lifetime ES2013801A6 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP25425187 1987-10-08
JP11999088 1988-05-17
JP63250811A JPH0753725B2 (ja) 1987-10-08 1988-10-06 ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤

Publications (1)

Publication Number Publication Date
ES2013801A6 true ES2013801A6 (es) 1990-06-01

Family

ID=27313952

Family Applications (8)

Application Number Title Priority Date Filing Date
ES8803062A Expired - Lifetime ES2013801A6 (es) 1987-10-08 1988-10-07 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903467A Expired - Lifetime ES2017838A6 (es) 1987-10-08 1989-10-13 Un procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903465A Expired - Lifetime ES2018112A6 (es) 1987-10-08 1989-10-13 Un procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903469A Expired - Lifetime ES2018113A6 (es) 1987-10-08 1989-10-13 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903463A Expired - Lifetime ES2018111A6 (es) 1987-10-08 1989-10-13 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903468A Expired - Lifetime ES2017839A6 (es) 1987-10-08 1989-10-13 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales>
ES8903464A Expired - Lifetime ES2017836A6 (es) 1987-10-08 1989-10-13 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903466A Expired - Lifetime ES2017837A6 (es) 1987-10-08 1989-10-13 Un procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.

Family Applications After (7)

Application Number Title Priority Date Filing Date
ES8903467A Expired - Lifetime ES2017838A6 (es) 1987-10-08 1989-10-13 Un procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903465A Expired - Lifetime ES2018112A6 (es) 1987-10-08 1989-10-13 Un procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903469A Expired - Lifetime ES2018113A6 (es) 1987-10-08 1989-10-13 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903463A Expired - Lifetime ES2018111A6 (es) 1987-10-08 1989-10-13 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903468A Expired - Lifetime ES2017839A6 (es) 1987-10-08 1989-10-13 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales>
ES8903464A Expired - Lifetime ES2017836A6 (es) 1987-10-08 1989-10-13 Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES8903466A Expired - Lifetime ES2017837A6 (es) 1987-10-08 1989-10-13 Un procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.

Country Status (16)

Country Link
US (1) US4954518A (en, 2012)
JP (1) JPH0753725B2 (en, 2012)
KR (1) KR910007970B1 (en, 2012)
AT (1) AT397088B (en, 2012)
AU (1) AU605363B2 (en, 2012)
BE (1) BE1002226A5 (en, 2012)
CA (1) CA1320959C (en, 2012)
CH (1) CH679397A5 (en, 2012)
DE (1) DE3834204A1 (en, 2012)
ES (8) ES2013801A6 (en, 2012)
FI (1) FI98460C (en, 2012)
FR (1) FR2621585B1 (en, 2012)
GB (1) GB2210879B (en, 2012)
IT (1) IT1235048B (en, 2012)
NL (1) NL194914C (en, 2012)
SE (1) SE468595B (en, 2012)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3924417A1 (de) * 1989-07-24 1991-01-31 Merck Patent Gmbh Chromanderivate
EP0419410A3 (en) * 1989-09-19 1991-08-14 Ciba-Geigy Ag Alkanophenones
JPH07110853B2 (ja) * 1990-09-07 1995-11-29 シェリング・コーポレーション 抗ウイルス化合物および抗高血圧化合物
FR2695387B1 (fr) * 1992-09-09 1994-10-21 Adir Nouveaux composés benzopyraniques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
ES2160626T3 (es) * 1993-04-09 2001-11-16 Toyama Chemical Co Ltd Inmunomodulador, inhibidor de la adherencia celular, y agente que permite tratar y prevenir enfermedades autoinmunes.
WO1995033462A1 (en) * 1994-06-02 1995-12-14 Smithkline Beecham Corporation Anti-inflammatory compounds
IT1288123B1 (it) 1996-09-04 1998-09-10 Nicox Sa Uso di nitroderivati per l'incontinenza urinaria
DK1043317T3 (da) 1997-11-19 2009-07-06 Kowa Co Pyridazinderivater og medikamenter indeholdende dem som aktiv bestanddel
TWI241295B (en) 1998-03-02 2005-10-11 Kowa Co Pyridazine derivative and medicine containing the same as effect component
US6649645B1 (en) * 1998-12-23 2003-11-18 Pharmacia Corporation Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
JP2000247959A (ja) 1999-02-26 2000-09-12 Kowa Co ピリダジン−３−オン誘導体及びこれを含有する医薬
JP2001055331A (ja) * 1999-06-11 2001-02-27 Toyama Chem Co Ltd アトピー性皮膚炎治療剤
US6664256B1 (en) 2000-07-10 2003-12-16 Kowa Co., Ltd. Phenylpyridazine compounds and medicines containing the same
GB0119865D0 (en) * 2001-08-14 2001-10-10 Cancer Res Campaign Tech DNA-PK inhibitors
GB0119863D0 (en) * 2001-08-14 2001-10-10 Cancer Res Campaign Tech DNA-PK inhibitors
AR038957A1 (es) 2001-08-15 2005-02-02 Pharmacia Corp Terapia de combinacion para el tratamiento del cancer
JP3972663B2 (ja) * 2002-01-22 2007-09-05 松下電器産業株式会社 高周波信号受信装置
US7049313B2 (en) * 2002-02-25 2006-05-23 Kudos Pharmaceuticals Ltd. ATM inhibitors
NZ536190A (en) * 2002-04-17 2007-08-31 Cytokinetics Inc Compounds for treating cellular proliferative diseases by modulating the activity of the mitotic kinesin KSP
EP1507756B1 (en) 2002-05-24 2015-07-22 Millennium Pharmaceuticals, Inc. Ccr9 inhibitors and methods of use thereof
AU2003252025A1 (en) * 2002-07-17 2004-02-02 Cytokinetics, Inc. Compounds, compositions, and methods
JP2005539062A (ja) * 2002-09-13 2005-12-22 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
AU2003298661B2 (en) 2002-11-18 2007-05-10 Chemocentryx, Inc. Aryl sulfonamides
US7741519B2 (en) * 2007-04-23 2010-06-22 Chemocentryx, Inc. Bis-aryl sulfonamides
US20070021466A1 (en) * 2002-11-18 2007-01-25 Solomon Ungashe CCR2 inhibitors and methods of use thereof
US7420055B2 (en) * 2002-11-18 2008-09-02 Chemocentryx, Inc. Aryl sulfonamides
US7227035B2 (en) * 2002-11-18 2007-06-05 Chemocentryx Bis-aryl sulfonamides
DE10256182A1 (de) * 2002-12-02 2004-06-24 Merck Patent Gmbh 2-Oxadiazolchromonderivate
US20070287844A1 (en) * 2003-03-14 2007-12-13 Toyama Chemical Co., Ltd. Novel Crystal of N-[3-(Formylamino)-4-Oxo-6-Phenoxy-4h-Chromene-7-Yl] Methanesulfonamide
EP1604984A1 (en) * 2003-03-18 2005-12-14 Kowa Co., Ltd. Water-soluble phenylpyridazine derivative and medicine containing the same
CN100387231C (zh) * 2003-03-24 2008-05-14 天津药物研究院 一种制备古拉替莫固体制剂的工艺及其固体制剂
ES2341342T3 (es) * 2003-08-13 2010-06-18 Kudos Pharmaceuticals Limited Aminopironas y su uso como inhibidores de atm.
US20050165089A1 (en) * 2003-10-06 2005-07-28 Gustave Bergnes Compounds, compositions and methods
EP1794151A1 (en) * 2004-09-20 2007-06-13 Kudos Pharmaceuticals Limited Dna-pk inhibitors
WO2006085067A1 (en) * 2005-02-09 2006-08-17 Kudos Pharmaceuticals Limited Atm inhibitors
AR054438A1 (es) * 2005-04-15 2007-06-27 Kudos Pharm Ltd Inhibidores de adn -pk
KR100704009B1 (ko) * 2005-08-30 2007-04-04 한국화학연구원 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(ｎ-메틸치환술폰아미도)메틸-2ｈ-1-벤조피란 유도체
TW200745094A (en) * 2005-08-31 2007-12-16 Kudos Pharm Ltd ATM inhibitor
CN101891726B (zh) * 2005-10-09 2012-05-23 天津药物研究院 艾拉莫德结晶形态及其组合物
CN101885717B (zh) * 2005-10-09 2012-05-23 天津药物研究院 艾拉莫德结晶形态及其组合物
CN101885718B (zh) * 2005-10-09 2012-05-23 天津药物研究院 艾拉莫德结晶形态及其组合物
JP4788955B2 (ja) * 2006-01-13 2011-10-05 住友金属工業株式会社 鉄道車両における操舵用アクチュエータの制御方法
AU2006233256B2 (en) * 2006-10-30 2012-01-19 Armaron Bio Pty Ltd Improved flavonols
US7960567B2 (en) * 2007-05-02 2011-06-14 Amgen Inc. Compounds and methods useful for treating asthma and allergic inflammation
UY31232A1 (es) * 2007-07-19 2009-03-02 Compuestos derivados de dibenzotifenilamino-cromen-4-onas activas sustituidas y sus isomeros y aplicaciones
JP5828235B2 (ja) 2011-07-21 2015-12-02 新日鐵住金株式会社 鉄道車両用操舵台車
PL2929880T3 (pl) * 2013-07-18 2017-03-31 Toyama Chemical Co., Ltd. Środek terapeutyczny do leczenia choroby, wykazujący hamujący wpływ na czynnik hamujący migrację makrofagów
CN107021891A (zh) * 2017-04-24 2017-08-08 常州佳德医药科技有限公司 一种艾拉莫德中间体的制备方法
CN106986797B (zh) * 2017-04-24 2018-09-28 常州佳德医药科技有限公司 N-(2-(4-乙酰苯氧基)-5-甲氧基苯基)甲磺酰胺及其制备方法
CN111170914B (zh) * 2018-11-09 2021-12-21 成都大学 硒/硫化磺酰芳胺类化合物及其硒/硫化方法
CN109705000A (zh) * 2019-02-26 2019-05-03 南京红杉生物科技有限公司 艾拉莫德中间体及其合成方法
JP7453365B2 (ja) * 2020-05-29 2024-03-19 富士フイルム富山化学株式会社 高純度のｎ－（５－メトキシ―２－フェノキシフェニル）メタンスルホンアミド及びその製造方法
CN113968836A (zh) * 2020-07-25 2022-01-25 华创合成制药股份有限公司 一种苯并吡喃衍生物及其在类风湿性关节炎治疗中的应用
CN113968838B (zh) * 2020-07-25 2024-04-02 华创合成制药股份有限公司 一种硫代苯并吡喃类化合物及其在类风湿性关节炎治疗中的应用
CN114539104A (zh) * 2022-03-09 2022-05-27 常州佳德医药科技有限公司 一种艾拉莫德中间体的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3661990A (en) * 1970-04-13 1972-05-09 Riker Laboratories Inc N-alkylsulfonyl benzoylhaloalkylsulfonanilides
US3689523A (en) * 1971-01-04 1972-09-05 Minnesota Mining & Mfg Substituted haloalkanesulfonanilides
US3840597A (en) * 1971-02-24 1974-10-08 Riker Laboratories Inc Substituted 2-phenoxy alkane-sulfonanilides
GB1499323A (en) * 1974-03-22 1978-02-01 Fisons Ltd 6-substituted chromones and chromanones
DE2537204A1 (de) * 1974-08-23 1976-03-04 Fisons Ltd Neue benzopyrane und verfahren zu ihrer herstellung
EP0009554B1 (de) * 1978-07-27 1983-04-27 Schering Aktiengesellschaft Indanyl-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE3110009A1 (de) * 1981-03-11 1982-09-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue benzofuran-derivate, ihre herstellung und verwendung
DE3208079A1 (de) * 1982-03-04 1983-09-08 Schering AG, 1000 Berlin und 4709 Bergkamen Neue indanyl-derivate, ihre herstellung und verwendung
FR2543140B1 (fr) * 1983-03-24 1985-06-21 Cortial Nouveaux acides flavone-carboxyliques-4', leur methode de preparation et leur application en therapeutique
DE3343331A1 (de) * 1983-11-28 1985-06-05 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von indanyl-derivaten und deren verwendung
US4713393A (en) * 1985-04-25 1987-12-15 Merck & Co., Inc. Phenylpropyl-2,3-dihydrobenzofurans useful as anti-inflammatory agents
PT86407B (pt) * 1986-12-31 1990-11-20 Fujisawa Pharmaceutical Co Processo para a preparacao de novos derivados de alcano-sulfonanilida, e de composicoes farmaceuticas compreendendo os mesmos

Also Published As

Publication number Publication date
FR2621585B1 (fr) 1994-01-28
DE3834204A1 (de) 1989-04-20
SE8803570L (sv) 1989-04-09
AU605363B2 (en) 1991-01-10
AT397088B (de) 1994-01-25
SE8803570D0 (sv) 1988-10-07
ES2018111A6 (es) 1991-03-16
IT8848441A0 (it) 1988-10-10
NL8802464A (nl) 1989-05-01
ES2017839A6 (es) 1991-03-01
FI884626A7 (fi) 1989-04-09
KR890006610A (ko) 1989-06-14
GB2210879A (en) 1989-06-21
GB2210879B (en) 1991-09-18
CH679397A5 (en, 2012) 1992-02-14
FI98460C (fi) 1997-06-25
ES2018112A6 (es) 1991-03-16
JPH0753725B2 (ja) 1995-06-07
CA1320959C (en) 1993-08-03
NL194914C (nl) 2003-07-04
IT1235048B (it) 1992-06-17
FI98460B (fi) 1997-03-14
ES2017838A6 (es) 1991-03-01
KR910007970B1 (ko) 1991-10-05
FR2621585A1 (fr) 1989-04-14
ES2017837A6 (es) 1991-03-01
FI884626A0 (fi) 1988-10-07
SE468595B (sv) 1993-02-15
ATA249588A (de) 1993-06-15
BE1002226A5 (fr) 1990-10-23
ES2017836A6 (es) 1991-03-01
AU2348988A (en) 1989-04-13
US4954518A (en) 1990-09-04
NL194914B (nl) 2003-03-03
ES2018113A6 (es) 1991-03-16
JPH0249778A (ja) 1990-02-20
DE3834204C2 (en, 2012) 1992-04-23
GB8823567D0 (en) 1988-11-16

Similar Documents

Publication Publication Date Title
ES2013801A6 (es) Procedimiento de preparacion de derivados de 4h-1-benzopiran-4-ona o sus sales.
ES2013067A6 (es) Un procedimiento para producir un derivado de piperazina.
AR037517A1 (es) Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria
ES483767A1 (es) Procedimiento para producir n-arilsulfonil-l-argininamidas
AR008377A1 (es) Un compuesto derivado de la 3-aroilbencilpiridazinona, una composicion farmaceutica particularmente para el tratamiento de enfermedades inflamatorias o autoinmunes que contiene dicho compuesto
ES2046383T3 (es) Nuevos derivados de acidos difosfonicos, procedimientos para su preparacion y medicamentos que contienen estos compuestos.
SE7614258L (sv) Forfarande for framstellning av kinazoloderivat
NO308659B1 (no) Nye 4,6-diarylpyrimidin-derivater, salter derav, anvendelse derav og farmasøytisk preparat
ES2143526T3 (es) Derivados de amida que tienen actividad antihipercolesterolemica, su preparacion y sus usos terapeuticos.
FI810604L (fi) Foerfarande foer framstaellning av indanderivat
PE20030738A1 (es) Sales de acido succinico de 5,7,14-triazatetraciclo[10.3.1.02,11.04,9] -hexadeca-2(11),3,5,7,9-pentaeno y composiciones farmaceuticas de las mismas
AR019496A1 (es) Azalidas de 13 miembros, composiciones farmaceuticas, uso en la preparacion de medicamentos y preparacion de los mismos
DE3362241D1 (de) Antifungal triazolyl propanol derivatives
ES2046193T3 (es) Un procedimiento para la preparacion de un compuesto de imidazolidinona.
ES2019840A6 (es) Procedimiento para preparar nuevos derivados de tieno-triazolo-diazepina.
IT1201934B (it) Derivati della paromomicina
ES2173195T3 (es) Derivados de antraciclina.
ES8601209A1 (es) Procedimiento para preparar derivados de 5h-(1)-benzopirano-(2,3-d)pirimidina
ES2122221T3 (es) Compuestos terapeuticos adecuados para el tratamiento de enfermedades conectadas con la deficiencia de glutation, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
AR248394A1 (es) Procedimiento para obtener nuevos derivados de la n-bencilpiridina.
MX9205921A (es) Derivados de bis(fenil)etano, proceso para su preparacion y composicion farmaceutica que los contiene
ES555206A0 (es) Procedimiento para preparar derivados berbanicos biologicamente activos.
SE8001981L (sv) Kompositioner for behandling av glaukom
ES2068813T3 (es) Derivados cefem de tiadiazolilacetamida.
ES8201525A1 (es) Un procedimiento para la preparacion de nuevos derivados de 1,1'-bifenil-2-il-alquilamina

Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-10-07

FD1A Patent lapsed

Effective date: 20081008