AR248394A1 - Procedimiento para obtener nuevos derivados de la n-bencilpiridina. - Google Patents

Procedimiento para obtener nuevos derivados de la n-bencilpiridina.

Info

Publication number
AR248394A1
AR248394A1 AR90318303A AR31830390A AR248394A1 AR 248394 A1 AR248394 A1 AR 248394A1 AR 90318303 A AR90318303 A AR 90318303A AR 31830390 A AR31830390 A AR 31830390A AR 248394 A1 AR248394 A1 AR 248394A1
Authority
AR
Argentina
Prior art keywords
processes
preparation
pharmaceutical compositions
pyridine derivatives
procedure
Prior art date
Application number
AR90318303A
Other languages
English (en)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Application granted granted Critical
Publication of AR248394A1 publication Critical patent/AR248394A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77—Hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER NUEVOS DERIVADOS DE N-BENCILPIRIDINA DE FORMULA (I) EN LA QUE Q REPRESENTA NITRO O CIANO, Y X1 Y X2, INDEPENDIENTEMENTE, REPRESENTAN HIDROGENO, HALOGENO, TRIFLUOROMETILO, ALQUILO INFERIOR, ALCOXI INFERIOR O NITRO. EL PROCEDIMIENTO CONSISTE EN HACER REACCIONAR UN DERIVADO DE AMINOPIRIDINA CON UN HALURO DE BENCILO, O UN DERIVADO DE IMINOPIRIDINA CON BROMURO DE CIANOGENO. LOS NUEVOS COMPUESTOS PRESENTAN ACCION INHIBIDORA DE LA SECRECION DE ACIDO GASTRICO, PROTECTORA DE TEJIDOS, ANALGESICA Y LIGERAMENTE ANTIINFLAMATORIA, Y SE PUEDEN EMPLEAR CON FINES TERAPEUTICOS.
AR90318303A 1989-11-07 1990-11-06 Procedimiento para obtener nuevos derivados de la n-bencilpiridina. AR248394A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU895807A HU207047B (en) 1989-11-07 1989-11-07 Process for producing new pyridine derivatives and pharmaceutical copositions comprising same

Publications (1)

Publication Number Publication Date
AR248394A1 true AR248394A1 (es) 1995-08-18

Family

ID=10970765

Family Applications (1)

Application Number Title Priority Date Filing Date
AR90318303A AR248394A1 (es) 1989-11-07 1990-11-06 Procedimiento para obtener nuevos derivados de la n-bencilpiridina.

Country Status (20)

Country Link
US (1) US5155123A (es)
EP (1) EP0427526B1 (es)
JP (1) JPH03169862A (es)
KR (1) KR910009663A (es)
CN (1) CN1052305A (es)
AR (1) AR248394A1 (es)
AT (1) ATE109137T1 (es)
AU (1) AU631261B2 (es)
CA (1) CA2029222A1 (es)
DE (1) DE69011046T2 (es)
DK (1) DK0427526T3 (es)
ES (1) ES2057441T3 (es)
FI (1) FI905493A0 (es)
HU (1) HU207047B (es)
IL (1) IL96252A (es)
IN (1) IN171700B (es)
NO (1) NO177263C (es)
NZ (1) NZ235984A (es)
PH (1) PH27440A (es)
ZA (1) ZA908889B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1035115B1 (en) 1999-02-24 2004-09-29 F. Hoffmann-La Roche Ag 4-Phenylpyridine derivatives and their use as NK-1 receptor antagonists
TWI280239B (en) 2003-07-15 2007-05-01 Hoffmann La Roche Process for preparation of pyridine derivatives
CN101267808A (zh) 2005-09-23 2008-09-17 弗·哈夫曼-拉罗切有限公司 新型制剂
EP2628389A4 (en) * 2010-08-31 2014-01-01 Meiji Seika Pharma Co Ltd AGENT FOR COMBATING HARMFUL ORGANISMS
BR112014004268A8 (pt) * 2011-08-26 2023-01-17 Meiji Seika Pharma Co Ltd método para a produção de agente de controle de praga
US20210238176A1 (en) 2018-08-07 2021-08-05 Syngenta Crop Protection Ag Pesticidally-active bicyclic heteroaromatic compounds
AR117291A1 (es) 2018-12-14 2021-07-28 Syngenta Crop Protection Ag Compuestos heterocíclicos de cianamida con actividad pesticida
WO2020169526A1 (en) 2019-02-18 2020-08-27 Syngenta Crop Protection Ag Pesticidally-active cyanamide heterocyclic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1201119A (en) * 1978-09-18 1986-02-25 Mcneilab, Inc. Diaza-cyclic derivatives of guanidine
HU188852B (en) * 1983-03-16 1986-05-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer
JPH07121909B2 (ja) * 1986-09-10 1995-12-25 日本バイエルアグロケム株式会社 新規複素環式化合物及び殺虫剤

Also Published As

Publication number Publication date
NO177263C (no) 1995-08-16
IN171700B (es) 1992-12-12
DE69011046D1 (de) 1994-09-01
AU6582390A (en) 1991-05-23
CA2029222A1 (en) 1991-05-08
JPH03169862A (ja) 1991-07-23
AU631261B2 (en) 1992-11-19
NZ235984A (en) 1992-08-26
ZA908889B (en) 1991-10-30
HU207047B (en) 1993-03-01
IL96252A (en) 1994-12-29
CN1052305A (zh) 1991-06-19
HU895807D0 (en) 1990-01-28
PH27440A (en) 1993-07-02
NO904822D0 (no) 1990-11-06
DE69011046T2 (de) 1994-11-24
EP0427526A1 (en) 1991-05-15
KR910009663A (ko) 1991-06-28
ES2057441T3 (es) 1994-10-16
FI905493A0 (fi) 1990-11-06
EP0427526B1 (en) 1994-07-27
US5155123A (en) 1992-10-13
NO904822L (no) 1991-05-08
ATE109137T1 (de) 1994-08-15
NO177263B (no) 1995-05-08
HUT55758A (en) 1991-06-28
DK0427526T3 (da) 1994-08-29
IL96252A0 (en) 1991-08-16

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