EP1802535B1 - Bouchon de fermeture pour recipients remplis de liquides medicaux - Google Patents

Bouchon de fermeture pour recipients remplis de liquides medicaux Download PDF

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Publication number
EP1802535B1
EP1802535B1 EP05770389A EP05770389A EP1802535B1 EP 1802535 B1 EP1802535 B1 EP 1802535B1 EP 05770389 A EP05770389 A EP 05770389A EP 05770389 A EP05770389 A EP 05770389A EP 1802535 B1 EP1802535 B1 EP 1802535B1
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EP
European Patent Office
Prior art keywords
membrane
closure cap
cap according
removal
cap
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EP05770389A
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German (de)
English (en)
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EP1802535A1 (fr
Inventor
Torsten Brandenburger
Ismael Rahimy
Gerald Wegner
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Fresenius Kabi Deutschland GmbH
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Fresenius Kabi Deutschland GmbH
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Application filed by Fresenius Kabi Deutschland GmbH filed Critical Fresenius Kabi Deutschland GmbH
Priority to PL05770389T priority Critical patent/PL1802535T3/pl
Publication of EP1802535A1 publication Critical patent/EP1802535A1/fr
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a closure cap for a container which is filled with a medical fluid, in particular for infusion or transfusion, in particular a filled with a liquid for parenteral nutrition bottle-shaped container. Moreover, the invention relates to a container for a medicinal liquid for infusion or transfusion, in particular a bottle-shaped container to be filled with a liquid for parenteral nutrition, which has such a closure cap.
  • the containers include on the one hand the known bags made of multilayer films, which are characterized by transparency, flexibility and sealability, on the other hand, the known bottles, which have different shapes.
  • the bags and bottles differ in the design of the approaches to the removal and supply of medical fluids, which are also referred to as a port.
  • the DE 102 23 560 A1 describes a bag with a port system comprising a withdrawal and injection point.
  • the port system has two separate connectors, one of which serves to remove the liquid and the other to inject an additive.
  • a so-called spike is generally used, which has a relatively large diameter, while for the injection of the additive, a cannula is used, which has a relatively small diameter.
  • different requirements are placed on the training of the collection and injection site.
  • a cap for a medicine bottle which has a sampling and injection point.
  • a common membrane made of an elastic material which is pierceable with a piercing (spike) of an infusion device for removing the drug and a cannula of a syringe for injecting an additive.
  • the membrane also called septum, is firmly welded to the cap.
  • a closure for a medicine bottle is also from the EP 0 364 783 B1 known. This closure is also characterized by a common septum for the port for removing the drug and injecting the additive.
  • the membranes used in medical technology must meet high requirements.
  • the membranes should on the one hand be pierceable with little effort and on the other hand safely seal the container.
  • the membrane should be sealed to seal the injection site after puncturing and removal of the cannula.
  • the membrane of the sampling point should also hold the piercing in tensile stress, so that the piercing part can not slide out of the puncture site.
  • the two membranes are identical.
  • the EP 0 495 330 A1 describes a device for providing access for a flexible container.
  • the known device has both a sampling point and an injection point.
  • the extraction and injection point are closed by membranes, which are designed differently.
  • the membrane of the sampling point is formed as a flat disc, which is widened at its edge, while the membrane of the injection point is curved on the top and bottom outward.
  • the membrane of the injection site is a self-sealing membrane.
  • the disadvantage is that the membrane of the sampling point is not self-sealing.
  • the object of the invention is to provide a closure cap for containers filled with medicinal liquids, in particular liquids for infusion or transfusion, with a withdrawal and injection site, which permits safe handling when the medical liquid is withdrawn and the additive is injected.
  • the removal and injection point are formed as separate accesses with different openings which are each closed by a pierceable self-sealing membrane.
  • the cap does not have a common membrane for both approaches, but two membranes that are designed differently. In this context, under different training, for example, different shapes or materials to understand.
  • the key advantage of the closure cap according to the invention is that the use of separate membranes for the extraction and injection point allows optimal adaptation to the different requirements that are placed on these approaches. Since the port system has membranes of different design, the extraction and injection point to the specific requirements when removing a liquid by means of a spiked part (spike), which has a relatively large diameter, and be optimally adapted when injecting an additive by means of a cannula has a relatively small diameter.
  • a spiked part spike
  • the membrane of the sampling point is designed such that the port can be pierced with a piercing part (spike), wherein the spike is held in tensile stress and the sampling point is securely sealed, while the membrane of the injection site is such that the port is sealed after puncture and removal of the cannula.
  • a piercing part spike
  • both membranes are clamped in the cap.
  • the membranes can also be deformed elastically. Consequently, the mounting of the cap can be done simply by pressing the individual parts in a simple manner. But it is also possible that the membranes are welded to the cap and / or glued.
  • a further preferred embodiment provides that the openings for the membranes are recesses in the cover part of the cap, in which the membranes are suitably inserted.
  • the positive connection ensures that the membranes have a secure fit.
  • a holding plate is arranged on the inside of the cover part of the cap, with which the membranes are clamped.
  • the retaining plate preferably on the membranes under cross-approaches.
  • An alternative embodiment provides the membranes under cross-approaches, which are not provided on a support plate, but on the inside of the cover part.
  • the lugs are preferably integral with the cover part.
  • the assembly can be further simplified if the lugs are bendable parts. Then the membranes need only be used in the lid part and the approaches to be bent.
  • the lugs are designed as annular flanges that provide a secure fit.
  • the holding plate is latching or snapping inserted into the cap.
  • the membranes are inserted into the lid part and then the holding plate in the side part of the cap.
  • the retaining plate may also be integral with the side part, wherein the lid part is formed as a hinged by the side part cap body. The membranes are then inserted into the folded cap body and the cap body is then folded onto the holding plate, so that the membranes between the cap body and holding plate are jammed.
  • the cap body is preferably attached to the side part with a hinge.
  • hinges are known as so-called film hinges in plastics technology.
  • the first and / or second opening in the cap are preferably closed with a twist-off part, which forms a tamper-evident closure.
  • the handling is preferably improved in that the Abcomp compiler are designed as flat handle parts.
  • the Abcomp compiler expediently each have a mark, in particular a trained in the manner of an arrow recess. Since the arrows point in opposite directions, it can immediately be recognized that the respective port is a withdrawal or injection point.
  • the self-sealing membrane of the extraction point preferably has an outer annular portion, which is followed by a central annular portion with an upper and lower abutment surface which is clamped in the cap.
  • the middle annular section merges into an inner dish-shaped section, on the upper side of which a trough-shaped depression is formed.
  • the inner dish-shaped section preferably has a flat underside.
  • the membrane of the donor site is preferably weakened, so that it can be easily pierced with a spike.
  • the membrane is pre-slit crosswise. But it can also be slotted star-shaped or provided only with a simple slot.
  • the membrane of the injection site differs from the membrane of the sampling site by its cross section in the center.
  • the membrane of the injection site has a larger cross-section than the membrane of the extraction site, i. one membrane is thicker in the center than the other membrane.
  • the membrane of the injection point preferably has an outer annular portion.
  • the inner plate-shaped portion connects directly, with trough-shaped depressions are formed both on the upper and lower side of the inner plate-shaped portion.
  • the inventive bottle-shaped container for medical fluids may have different shapes. In addition to round shapes, oval or flattened shapes are also possible.
  • FIG. 1 shows a first embodiment of the closure cap according to the invention for bottle-shaped containers, in particular with a liquid for parenteral nutrition filled bottles.
  • the closure cap is an injection molded part, which is preferably made of polyolefins, in particular PP, PE, PET and blends.
  • the cap 1 has a round lid part 2, to which a cylindrical side part 3 is connected. At the bottom of the side part 3 is a flange 4 for attaching the cap to the head of a bottle.
  • the cover part 2 has a greater wall thickness than the side part 3.
  • the cap 1 has a port system 5 with a removal point 6 and an injection point 7.
  • the port system is described in detail below.
  • the cover part 2 of the cap 5 has two openings 8, 9 with preferably circular cross-section, which are arranged at a distance to each other.
  • a first self-sealing membrane 10 for the removal point 6 and in the second opening 9, a second self-sealing membrane 11 for the injection point.
  • Both membranes are designed differently. They consist of an elastic material, preferably of a synthetic rubber, preferably of polyisoprene.
  • the first membrane 10 for the withdrawal point 6 has an outer annular portion 10a, which is followed by a central annular portion 10b, which has a smaller diameter than the outer portion.
  • the middle annular portion 10b having upper and lower abutment surfaces is clamped.
  • the middle annular portion 10b merges into an inner dish-shaped portion 10c, on the upper side of which an upper trough-shaped depression 10d is formed.
  • the dish-shaped portion 10c has a flat bottom 10e.
  • the dish-shaped section is pre-slit in a crosswise or star-shaped manner, so that, although weakened, the elastic material is not severed.
  • the second diaphragm 11 for the injection point 7, which is thicker than the first diaphragm 10, has an outer annular portion 11 a with an upper and lower abutment surface, which is clamped in the cap.
  • an inner plate-shaped portion 11 b To the annular portion 11 a is followed directly by an inner plate-shaped portion 11 b, at the top and bottom of an upper or lower trough-shaped recess 11 c, 11 d are formed.
  • the trough-shaped depressions 11 c and 11 d of the second membrane 10 have a smaller depth than the trough-shaped depression 10 d of the first membrane 10.
  • the two membranes 10, 11 are clamped by means of a holding plate 13, which snaps into the side part 3 of the cap or latching is used.
  • the edge of the holding plate 13 is seated in an annular groove 14 which extends on the inside of the side part 3 below the lid part 2.
  • the cover part 2 of the cap 1 has a shape complementary to the membranes 10, 11, so that the membranes fit snugly in the cover part.
  • the membranes were supported with the upper abutment surfaces on the underside of the cover part 2.
  • the holding plate 13 has two openings 8 a and 9 a, which have the same or a larger diameter as the corresponding openings 8 and 9 of the cover part 2.
  • the openings 8a and 9a are surrounded by annular projections 15, 16, which bear against the lower abutment surfaces of the membranes 10, 11.
  • the membranes 10, 11 are inserted into the openings 8, 9 of the cover part 2 of the cap 1. Then, the holding plate 13 is inserted into the cap 1, so that the membranes 10, 11 are clamped between the cover part and the holding plate.
  • the removal point 6 and injection point 7 of the cap are each closed with a twist-off 17, 18, which forms a tamper-evident closure.
  • Both Abwindmaschine 17, 18 are formed as flat handle parts, which are each connected via a ring breaking zone 19, 20 to the cover part 2. These handles are easy to turn off by hand.
  • the handle portion 17 has a recess 21 formed in the manner of an arrow, which points upwards, while the handle portion 18 has a recess 22 formed in the manner of an arrow, which points downwards. This makes it clear that after turning off the grip part 17, the removal point 6 and after turning off the grip part 18, the injection point is exposed.
  • the grip part 17 of the removal point 6 is turned off and a puncturing part (not shown), for example the spike of a transfer device for enteral nutrient solutions, or an infusion device inserted into the opening 8 of the lid part 2.
  • a puncturing part for example the spike of a transfer device for enteral nutrient solutions, or an infusion device inserted into the opening 8 of the lid part 2.
  • the pre-slit membrane 10 is pierced, so that the access to the container is made.
  • the grip part 18 is broken off and the cannula of a syringe is pricked into the membrane 11 of the injection site 7.
  • FIG. 2 shows an alternative embodiment of the with reference to the FIG. 1 described embodiment.
  • the cap of FIG. 2 is different from the cap of FIG. 1 only in that the cover part 2 'designed as a hinged cap body and the holding plate 13' is integral with the cap. Otherwise, both caps have the same training. Therefore, the same reference numerals are used for the corresponding parts.
  • the cover part 2 'of the cap 1' of FIG. 2 is attached by means of a film hinge 30, which extends only over part of the circumference of the cap, at the edge of the side part 3.
  • the film hinge 30 is diametrically opposite a snap closure 31, which also extends only over part of the circumference of the cap.
  • the snap closure 31 is formed by a projecting lug 31 a at the edge of the lid part 2 'and an undercut groove 31 b at the edge of the side part 3.
  • the two membranes 10, 11 are inserted into the folded lid part 2 ', and the lid part 2' is folded onto the holding plate 13 ', wherein the projection 31a snaps into the groove 31b.
  • the membranes are clamped again between holding part and cover part.
  • FIGS. 3a and 3b show a further embodiment of the closure cap, which differs from those with reference to the Figures 1 and 2 described embodiments characterized differs in that a holding plate is not provided.
  • the corresponding parts are again denoted by the same reference numerals.
  • the lugs 15 ', 16' for clamping the membranes 10, 11 are annular sleeves on the underside of the cover part 2, whose diameter corresponds to the diameter of the openings 8, 9.
  • the sleeve-shaped projection 15 'of the removal point 6 has a greater length than the projection 16' of the injection point. 7
  • the membranes 10, 11 are first inserted into the openings 8, 9 ( FIG. 3a ). Then the lugs 15 ', 16' are bent so that they rest against the lower contact surfaces of the membranes, so that the membranes are clamped. In the membrane 11 of the injection point 7 it is sufficient to bend the projection 16 'by 90 °. The projection 15 'of the removal point 6, however, is crimped around the outer annular portion 10a of the membrane ( FIG. 3b ).
  • FIG. 4 shows the lower portion of the lid portion of the cap of another embodiment, which differs from the other embodiments in that in the region where the lugs 15 ', 16' are bent, an annular groove 31, 32 is provided. Since the approaches are weakened in this area, the bending of the same is simplified.
  • FIG. 5 shows a bottle-shaped container 33 which is closed with the cap 1.
  • the cap 1 is firmly welded to the head 34 of the bottle 34. Between the cap 1 and the bottle head 34 sits a rubber disc, not shown.
  • the container is filled with a liquid for a parenteral nutrition.
  • the container may also be filled with an infusion or transfusion solution.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Closures For Containers (AREA)

Claims (27)

  1. Bouchon de fermeture (1) pour des récipients contenant des liquides médicaux, en particulier des récipients contenant des liquides pour perfusion ou transfusion, comportant un point de prélèvement et d'injection (6, 7) pour le prélèvement du liquide médical et l'injection d'un additif, le point de prélèvement et d'injection (6, 7) étant réalisé sous forme d'accès séparés vers une première ouverture (8) pour le prélèvement d'un liquide, laquelle est obturée par une première membrane (10) auto-étanchéifiante, apte à être transpercée, et vers une deuxième ouverture (9) pour l'injection de l'additif, laquelle est obturée par une deuxième membrane (11) auto-étanchéifiante, apte à être transpercée, caractérisé en ce que la première et la deuxième membrane aptes à être transpercées sont réalisées différemment l'une de l'autre, et en ce que la première membrane (10) en tant que membrane auto-étanchéifiante est réalisée de telle sorte que pour le prélèvement d'un liquide la première membrane est transpercée au moyen d'une pointe d'un dispositif de transfert pour des solutions de produits de nutrition entérale ou d'un dispositif de transfusion et, après le transpercement, la pointe peut être maintenue pour une étanchéité sûre de la première membrane en cas de sollicitations de traction, et la deuxième membrane (11) en tant que membrane auto-étanchéifiante est réalisée de telle sorte que pour l'injection d'un additif la deuxième membrane peut être transpercée par une canule d'une seringue, ladite canule ayant un diamètre inférieur à celui de la pointe.
  2. Bouchon de fermeture selon la revendication 1, caractérisé en ce que la première et/ou la deuxième membrane (10, 11) du point de prélèvement et d'injection (6, 7) sont maintenues par blocage.
  3. Bouchon de fermeture selon la revendication 1 ou 2, caractérisé en ce que ledit bouchon comporte un couvercle (2) et une partie latérale (3), la première et la deuxième ouverture (8, 9) étant des évidements réalisés dans le couvercle, dans lesquels sont insérées de manière ajustée la première et la deuxième membrane (10, 11).
  4. Bouchon de fermeture selon la revendication 3, caractérisé en ce que sur la face intérieure du couvercle (2) est agencée une plaquette de fixation (13, 13'), par laquelle sont bloquées la première et la deuxième membrane (10, 11) du point de prélèvement et d'injection (6, 7).
  5. Bouchon de fermeture selon la revendication 4, caractérisé en ce que la plaquette de fixation (13, 13') comporte des saillies (15, 16) enserrant par le dessous la première et/ou la deuxième membrane (10, 11) du point de prélèvement et d'injection (6, 7).
  6. Bouchon de fermeture selon la revendication 3, caractérisé en ce que sur la face intérieure du couvercle (2) sont disposées des saillies (15', 16') enserrant par le dessous la première et/ou la deuxième membrane (10, 11) du point de prélèvement et d'injection (6, 7).
  7. Bouchon de fermeture selon la revendication 6, caractérisé en ce que les saillies (15', 16') sont réalisées d'un seul tenant avec le couvercle (2).
  8. Bouchon de fermeture selon la revendication 6 ou 7, caractérisé en ce que les saillies (15', 16') sont réalisées sous forme de bord rabattu annulaire.
  9. Bouchon de fermeture selon la revendication 4 ou 5, caractérisé en ce que la plaquette de fixation (13) est insérée par enclenchement ou encliquetage dans le bouchon.
  10. Bouchon de fermeture selon la revendication 4, 5 ou 9, caractérisé en ce que la plaquette de fixation (13) est réalisée d'un seul tenant avec la partie latérale (3), le couvercle (2) étant réalisé sous la forme d'un corps de bouchon rabattable sur la partie latérale.
  11. Bouchon de fermeture selon la revendication 10, caractérisé en ce que le couvercle (2) est fixé sur la partie latérale (3) au moyen d'une charnière (30).
  12. Bouchon de fermeture selon l'une quelconque des revendications 1 à 11, caractérisé en ce que la première et/ou la deuxième ouverture (8, 9) sont obturées chacune par un élément (17, 18) détachable par torsion.
  13. Bouchon de fermeture selon la revendication 12, caractérisé en ce que les éléments (17, 18) détachables par torsion sont réalisés sous forme d'éléments de préhension plats.
  14. Bouchon de fermeture selon la revendication 12 ou 13, caractérisé en ce que les éléments (17, 18) détachables par torsion sont caractérisés différemment l'un de l'autre.
  15. Bouchon de fermeture selon la revendication 14, caractérisé en ce que les éléments (17, 18) détachables par torsion comportent chacun un évidement (21, 22) réalisé en forme de flèche, lesdites flèches étant dirigées dans des directions opposées l'une à l'autre.
  16. Bouchon de fermeture selon l'une quelconque des revendications 1 à 15, caractérisé en ce que la première membrane (10) du point de prélèvement (6) comporte, sur la face supérieure, un creux en forme de cuvette (10d).
  17. Bouchon de fermeture selon la revendication 16, caractérisé en ce que la première membrane (10) comporte une partie extérieure (10a) annulaire, qui est prolongée par une partie médiane (10b) annulaire, qui est munie d'une surface d'appui supérieure et inférieure et qui est maintenue par blocage dans le capuchon, la partie médiane annulaire se prolongeant par une partie intérieure (10c) en forme de plateau, dans laquelle est réalisé le creux (10d) supérieur en forme de cuvette.
  18. Bouchon de fermeture selon la revendication 17, caractérisé en ce que la partie intérieure (10c) en forme de plateau comporte une face inférieure (10e) plate.
  19. Bouchon de fermeture selon la revendication 17 ou 18, caractérisé en ce que la partie médiane (10b) annulaire a une section inférieure à celle de la partie extérieure (10a) annulaire de la première membrane (10).
  20. Bouchon de fermeture selon l'une quelconque des revendications 1 à 19, caractérisé en ce que la première membrane (10) du point de prélèvement (6) comporte au centre une section inférieure à celle de la deuxième membrane du point d'injection (7) .
  21. Bouchon de fermeture selon l'une quelconque des revendications 1 à 20, caractérisé en ce que la première membrane (10) du point de prélèvement (6) est affaiblie, de préférence préalablement fendue.
  22. Bouchon de fermeture selon l'une quelconque des revendications 1 à 21, caractérisé en ce que la deuxième membrane (11) du point d'injection (7) comporte, sur la face supérieure et la face inférieure, un creux (11c, 11d) en forme de cuvette.
  23. Bouchon de fermeture selon la revendication 22, caractérisé en ce que la deuxième membrane comporte une partie extérieure (11a) annulaire, qui est munie d'une surface d'appui supérieure et inférieure, qui est maintenue par serrage dans le bouchon, qui est prolongée par une partie intérieure (11b) en forme de plateau, dans laquelle sont réalisés le creux supérieur et inférieur (11c, 11d) en forme de cuvette.
  24. Bouchon de fermeture selon l'une quelconque des revendications 1 à 23, caractérisé en ce que la première et/ou la deuxième membrane du point de prélèvement et d'injection (6, 7) sont réalisées en caoutchouc synthétique, de préférence en polyisoprène.
  25. Bouchon de fermeture selon l'une quelconque des revendications 1 à 24, caractérisé en ce que le bouchon est une pièce moulée par injection, de préférence en polyoléfine.
  26. Récipient pour liquides médicaux, en particulier des liquides pour perfusion ou transfusion, comportant un bouchon selon l'une quelconque des revendications 1 à 25.
  27. Récipient selon la revendication 26, caractérisé en ce que le récipient est un récipient en forme de flacon.
EP05770389A 2004-10-20 2005-08-12 Bouchon de fermeture pour recipients remplis de liquides medicaux Active EP1802535B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL05770389T PL1802535T3 (pl) 2004-10-20 2005-08-12 Kołpak zamykający do pojemników napełnionych płynami leczniczymi

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004051300A DE102004051300C5 (de) 2004-10-20 2004-10-20 Verschlusskappe für mit medizinischen Flüssigkeiten befüllte Behältnisse
PCT/EP2005/008787 WO2006042579A1 (fr) 2004-10-20 2005-08-12 Bouchon de fermeture pour recipients remplis de liquides medicaux

Publications (2)

Publication Number Publication Date
EP1802535A1 EP1802535A1 (fr) 2007-07-04
EP1802535B1 true EP1802535B1 (fr) 2009-11-18

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Country Status (17)

Country Link
US (1) US8211081B2 (fr)
EP (1) EP1802535B1 (fr)
JP (1) JP4903708B2 (fr)
KR (1) KR101215752B1 (fr)
CN (1) CN101044069B (fr)
AT (1) ATE449012T1 (fr)
AU (1) AU2005297511B2 (fr)
BR (1) BRPI0517279B1 (fr)
CA (1) CA2584384C (fr)
DE (2) DE102004051300C5 (fr)
DK (1) DK1802535T3 (fr)
EA (1) EA009498B1 (fr)
ES (1) ES2332417T3 (fr)
MX (1) MX2007004706A (fr)
PL (1) PL1802535T3 (fr)
WO (1) WO2006042579A1 (fr)
ZA (1) ZA200703192B (fr)

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DE102004051300C5 (de) 2004-10-20 2013-01-24 Fresenius Kabi Deutschland Gmbh Verschlusskappe für mit medizinischen Flüssigkeiten befüllte Behältnisse
DE102007005407A1 (de) * 2007-02-03 2008-08-07 Fresenius Kabi Deutschland Gmbh Verschlusskappe für ein Behältnis zur Aufnahme von medizinischen Flüssigkeiten und Behältnis zur Aufnahme von medizinischen Flüssigkeiten
DE102007024539A1 (de) * 2007-05-24 2008-11-27 Fresenius Kabi Deutschland Gmbh Verschlusskappe für ein Behältnis zur Aufnahme von Flüssigkeiten, insbesondere einer enteralen Nährlösung und Behältnis mit einer derartigen Verschlusskappe
CN101081192B (zh) * 2007-07-03 2011-10-05 王建友 一种输液瓶口装置
DE102008007252A1 (de) * 2008-02-01 2009-08-13 Plümat Plate & Lübeck GmbH & Co. Verschlusskappe für Behälter
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JP2008516707A (ja) 2008-05-22
ZA200703192B (en) 2008-09-25
CN101044069B (zh) 2010-08-25
KR101215752B1 (ko) 2012-12-27
US8211081B2 (en) 2012-07-03
DK1802535T3 (da) 2010-01-25
ATE449012T1 (de) 2009-12-15
ES2332417T3 (es) 2010-02-04
DE502005008558D1 (de) 2009-12-31
JP4903708B2 (ja) 2012-03-28
CN101044069A (zh) 2007-09-26
WO2006042579A1 (fr) 2006-04-27
EP1802535A1 (fr) 2007-07-04
DE102004051300C5 (de) 2013-01-24
AU2005297511B2 (en) 2012-02-02
DE102004051300B3 (de) 2005-11-17
CA2584384C (fr) 2017-04-11
KR20070083666A (ko) 2007-08-24
CA2584384A1 (fr) 2006-04-27
PL1802535T3 (pl) 2010-04-30
EA009498B1 (ru) 2008-02-28
BRPI0517279B1 (pt) 2018-06-12
EA200700905A1 (ru) 2007-10-26
BRPI0517279A (pt) 2008-10-07
MX2007004706A (es) 2007-06-14
AU2005297511A1 (en) 2006-04-27

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