EP2114345B1 - Capuchon de fermeture pour un récipient destiné à recevoir des liquides médicaux et récipient destiné à recevoir des liquides médicaux - Google Patents

Capuchon de fermeture pour un récipient destiné à recevoir des liquides médicaux et récipient destiné à recevoir des liquides médicaux Download PDF

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Publication number
EP2114345B1
EP2114345B1 EP08707528.9A EP08707528A EP2114345B1 EP 2114345 B1 EP2114345 B1 EP 2114345B1 EP 08707528 A EP08707528 A EP 08707528A EP 2114345 B1 EP2114345 B1 EP 2114345B1
Authority
EP
European Patent Office
Prior art keywords
closure cap
recess
closure
injection
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP08707528.9A
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German (de)
English (en)
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EP2114345A1 (fr
Inventor
Torsten Brandenburger
Gerhard Greier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Kabi Deutschland GmbH
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Fresenius Kabi Deutschland GmbH
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Publication of EP2114345A1 publication Critical patent/EP2114345A1/fr
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Publication of EP2114345B1 publication Critical patent/EP2114345B1/fr
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1418—Threaded type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1431—Permanent type, e.g. welded or glued
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/18—Arrangements for indicating condition of container contents, e.g. sterile condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2044—Separating means having slits
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a closure cap for a container for holding medical fluids, in particular an infusion or transfusion container, which has a cover part and a peripheral part. Moreover, the invention relates to a container for receiving medical fluids, in particular a BFS container, with such a cap.
  • BFS method As a blow-fill-seal method (BFS method), a method is known in which containers, such as bottles of extruded PE or PP, in a single operation sterile and pyrogen-free blown into a desired shape and immediately after cooling with a sterile filling aseptically filled and hermetically sealed.
  • the containers produced by the bubble-fill-seal method, in particular bottles, are also referred to as BFS containers.
  • the containers When the known BFS containers are used for receiving sterile, medical liquids, for example infusion solutions, the containers require a closure cap system which allows a transfer of the infusion solution by means of an infusion device to the patient.
  • a closure cap system which allows a transfer of the infusion solution by means of an infusion device to the patient.
  • medication to the infusion solution should also be possible.
  • the closest prior art DE 10 2004 051 300 B3 thus opens a cap, the connecting parts of injection part and removal part have a break-off at a ring break zone.
  • the dispensing part is for removing the infusion solution by means of a spike, while the injection part is used for supplying a drug by means of a syringe having a thin cannula (needle).
  • the injection part comprises a tubular connection part which is closed by a protective cap designed as a break-off part.
  • a self-sealing membrane serum
  • a pierceable membrane in the connector prevents the septum from contacting the solution prior to use of the infusion bag.
  • the sampling part does not have a self-sealing septum.
  • the from the WO 96/23545 known injection and withdrawal part is intended to be welded into an infusion bag.
  • the known Zuspritzmaschine have proven. From the use of an injection needle for injecting an active ingredient, however, there are disadvantages. First, there is a risk that the connection between the injection needle and the septum due to an unintentional pull on the syringe or an overpressure inside the bag dissolves. On the other hand, there is an increased risk of injury to the nursing staff through the injection needle. Also, the infusion bag, in which the injection part is welded, can be damaged by improper handling by the needle. The addition of a viscous drug is more difficult due to the small cross section of the needle beyond. Incidentally, the supply of a liquid agent due to the small cross section of the needle requires a relatively long time.
  • conical connections with a conical shank and a conical sleeve are known in medical technology whose conical surfaces are normalized.
  • the non-lockable conical connections with normalized conical surfaces are referred to as luer connectors and the lockable conical connections as luer lock connectors.
  • Tapered Luer or Luer-Lock connectors are referred to as male connectors and tapered sleeve connectors as female connectors.
  • the DE 103 48 016 A1 describes a connector to be welded into an infusion bag that allows the injection of an agent by means of a conventional luer-lock syringe that does not have an injection needle.
  • the known connector has a connection part which has a channel-shaped recess in which a self-sealing membrane is arranged.
  • a break-off part which is connected to the connecting part, closes the channel-shaped recess.
  • the connecting part is designed as a connecting piece with an inner cone and an outer thread, wherein the membrane for sealingly receiving the Taper shank of a syringe is slotted.
  • the connector is composed of an upper and a lower section, between which the self-sealing membrane is clamped.
  • a closure cap for a BFS container which has a lid part and a peripheral part, wherein in the lid part a slotted membrane is used, which allows the imports of the spike of an infusion device.
  • the slotted membrane sits flush in the cover part of the cap.
  • the invention has for its object to provide a cap for a container for receiving medical fluids, in particular a BFS container, which allows the injection of a liquid without the use of an injection cannula. Moreover, it is an object of the invention to provide a container for receiving medical fluids, in particular a BFS container, which allows the injection of a liquid without the use of an injection cannula.
  • the closure cap according to the invention for a container for holding medical fluids in particular a BFS container for holding an infusion solution, has a cover part and a rim part, wherein an injection part for injecting a medical fluid is arranged in the cover part.
  • the injection part has an outwardly pointing connection part with a conical recess for sealingly receiving the conical shaft of a needleless injection syringe and an inwardly pointing closure part which has a self-sealing membrane for closing the recess of the connection part.
  • the self-sealing membrane is slotted so that the cone shank of the syringe can be easily inserted. It is advantageous that the closure cap according to the invention with the exception of the self-sealing membrane is formed in one piece. As a result, the production of the cap in large quantities at low cost is possible.
  • the closure part of the injection part has a recess in which the self-sealing membrane is inserted in a snap-fit manner.
  • the self-sealing membrane is clamped by an inwardly projecting edge of the closure member in the recess.
  • the closure part can also have distributed circumferentially arranged hooks for clamping fixation of the self-sealing membrane.
  • the recess of the closure part has a first cylindrical portion adjoining the lid portion and a second cylindrical portion adjoining the first cylindrical portion, the first cylindrical portion having a smaller inner diameter than the second cylindrical portion Section has.
  • a preferred embodiment of the closure cap provides that the self-sealing membrane has an annular portion which is arranged in the second cylindrical portion of the recess with the larger inner diameter, and has a plate-shaped portion adjoining the annular portion via a central web, which in the first cylindrical portion having the smaller inner diameter is arranged.
  • the self-sealing membrane has a secure hold in the recess of the closure part.
  • the plate-shaped portion of the self-sealing membrane has a trough-shaped depression.
  • the trough-shaped depression ensures, on the one hand, that the cone shank of the syringe is securely guided and, on the other hand, ensures that the membrane seals securely after pulling out the conical shank. It has been shown in experiments that the special design of the membrane for the immediate Resealing is crucial, with increasing internal pressure in the package, the sealing of the membrane is still increased.
  • the closure part of the injection part is formed with the self-sealing membrane such that upon insertion of the conical shaft of the injection syringe, the membrane is compressed in the recess in the axial direction.
  • the membrane opens when inserting the conical shaft.
  • the self-sealing membrane is on the one hand sufficiently fixed in the recess of the closure part, but on the other hand so freely movable that the membrane can be compressed in the axial direction during insertion of the conical shaft.
  • the height of the membrane is reduced, i. the top of the diaphragm loses its contact with the contact surface of the recess of the closure part.
  • the closure part of the injection part can be designed either for a luer syringe or a luer lock syringe.
  • the connecting part of the injection part has an external thread, so that a Luer-lock connection with the syringe is possible.
  • connection part For aseptic closure of the self-sealing membrane, the connection part is closed with a break-off part, which is connected to the upper end of the connection part via a ring-breaking zone. After breaking off the break-off part, the self-sealing membrane is exposed, so that the cone shank of the syringe can be inserted.
  • the break-off part has a lateral grip tab which extends up to the edge part of the cover part of the closure cap.
  • the closure cap according to the invention also has a removal part for removing a medical liquid with a spike.
  • the extraction part also has an outwardly facing fitting with a recess into which a spike is inserted and an inwardly facing closure part which is closed by a pierceable membrane.
  • the pierceable membrane is inserted snapping into a recess of the closure part of the removal part.
  • the membrane is clamped by an inwardly projecting edge of the closure part.
  • the connection part of the removal part is also closed with a break-off part, which is connected to the upper end of the connection part via a ring-break zone.
  • the break-off part of the removal part also has a lateral grip tab which extends up to the edge part of the cover part.
  • the container according to the invention in particular infusion or transfusion container, which is preferably designed as a bottle, is closed with the closure cap described above.
  • FIGS. 1 and 2 show the closure cap according to the invention in the side view which has an injection part A and a removal part B.
  • the closure cap is a one-piece plastic part which can be produced inexpensively in large quantities.
  • the closure cap 1 has a lid part 2 and a rim part 3.
  • the lid member 2 has an outer portion 4 and an inner portion 5 projecting outwardly. From the inner outwardly projecting portion 5 has a connecting part 6 for inserting the conical shank of a needleless injection syringe to the outside ( Fig. 3 ).
  • the connecting part 6 has a conical recess 7 for sealingly receiving the conical shaft of the syringe and an external thread 8.
  • the conical recess 7 and the external thread 8 are formed such that a commercially available Luer-lock syringe can be connected to the connecting part.
  • connection part 6 is closed with a break-off part 9, which is connected via a ring breaking zone 10 to the upper end of the connecting part.
  • the break-off part 9 has a round cap 11, to which a lateral tab 12 adjoins a narrow web 12, which extends down to the edge part of the cover part.
  • the grip tab 13 is designed such that it does not extend laterally beyond the closure cap.
  • a closure part 14 From the central portion 5 of the lid part 2, a closure part 14 has inwardly, which has a recess 15. In the recess 15 of the closure part 14, a self-sealing membrane 16 is inserted, which sits snapping into the recess.
  • the recess 15 of the closure part 14 has an upper cylindrical portion 17, which adjoins the central portion 5 of the lid part 2.
  • the upper cylindrical portion 17 is followed by a lower cylindrical portion 18 having a larger inner diameter than the upper cylindrical portion 17.
  • the Self-sealing membrane 16 has correspondingly a lower annular portion 19 with a larger outer diameter, which sits in the lower cylindrical portion 18 of the recess 15.
  • the closure part has an inwardly projecting edge 35, which fixes the membrane 16 in a clamping manner.
  • the dish-shaped portion 21 of the membrane 16 has a trough-shaped recess 22, which is provided with one or more slots 23, for example, is slotted crosswise.
  • the edge part 3 of the closure cap 1 has a lower bead-shaped edge 24, which has a circumferential groove 25 on the underside.
  • the cap can be placed on a bottle, wherein the upper edge of the bottle neck engages in the groove 25 of the bead-shaped edge 24 of the cap.
  • the break-off part 9 is first broken off from the connection part 6 by lateral pivoting of the handle bottle 13.
  • the self-sealing membrane 16 is exposed.
  • the conical taper shank 36 of a needleless injection syringe 26 is inserted into the conical recess 7 of the connection part 6.
  • the conical shaft 36 presses on the plate-shaped portion 22 of the self-sealing membrane 16, whereby the membrane is pressed together ( FIG. 4C ).
  • the middle web 20 of the membrane 16 presses inwards, wherein the plate-shaped portion 22 is opened in the region of the slots 23.
  • the drug can now be injected.
  • the closure cap also has a removal part B.
  • the injection and removal part A, B are laterally the axis of the closure cap arranged side by side in the middle section 5 of the cover part 2 of the closure cap.
  • the removal part B has the same construction as the injection part A (FIG. Fig. 5 ).
  • the removal part B has a connecting part 27, which points outwards from the middle section 5 of the cover part 2 and has a recess 28 for insertion of the spike of an infusion device.
  • the recess 28 of the connecting part 27 is closed by a break-off part 29, which is connected via a ring breaking zone 30 to the upper end of the connecting part.
  • the break-off part 30 again has a lateral grip bottle 31, which is designed like the grip tab of the break-off part of the injection part.
  • From the central portion 5 of the cover part 2 has a closure member 32 down, in which a pierceable by a spike membrane 33 is fixed by clamping.
  • the membrane 33 is held by an inwardly projecting edge 34 of the closure member 32. After breaking off the break-off part 29, the membrane 33 is exposed, which is pierced by the spike. With the spike, a liquid can be removed.
  • FIG. 6 shows the closure cap according to the invention together with a container according to the invention, which is a BFS bottle in the present embodiment.
  • the cap 1 is firmly seated on the bottle neck 37 of the bottle 38, which is filled with an infusion solution, for example. Since the bottleneck is not closed in the head area, but open, the liquid is in direct contact with the cap. Thus, it is possible to inject a drug with a needleless injection syringe.
  • the closure cap is preferably designed as a screw cap, which is screwed onto the bottle neck 37. But it is also possible to weld the cap with the bottleneck.

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Closures For Containers (AREA)

Claims (11)

  1. Capuchon de fermeture pour un récipient comportant un espace intérieur destiné à recevoir des liquides médicaux, en particulier un récipient BFS, qui présente une partie de couvercle (2) et une partie de bord (3), dans lequel
    - dans la partie de couvercle (2) est disposée une partie d'injection (A) pour l'injection un liquide médical, qui présente une partie de raccordement (6) orientée vers l'extérieur avec un évidement conique (7) destiné à recevoir de manière étanche la tige conique d'une seringue d'injection sans aiguille et une partie de fermeture (14) orientée vers l'intérieur, qui présente une membrane (16) à étanchéité intrinsèque, pour fermer l'évidement de la partie de raccordement, laquelle est fendue, dans lequel
    la partie de raccordement (6) de la partie d'injection (A) est fermée avec une partie de rupture (9), qui est reliée par une zone de rupture annulaire (10) à l'extrémité supérieure de la partie de raccordement (6), et la partie de rupture (9) présente une patte de saisie latérale (13) qui s'étend jusqu'à la partie de bord (3) du capuchon de fermeture, et
    - dans la partie de couvercle (2) est disposée une partie de prélèvement (B) pour prélever un liquide médical avec une pointe, qui présente une partie de raccordement (27) orientée vers l'extérieur avec un évidement (28) destiné à recevoir une pointe et une partie de fermeture (32) orientée vers l'intérieur, qui présente une membrane perforable (33) destinée à fermer l'évidement de la partie de raccordement, dans lequel la partie de raccordement (27) de la partie de prélèvement (B) est fermée avec une partie de rupture (29), qui est reliée par une zone de rupture annulaire (30) à l'extrémité supérieure de la partie de raccordement (27) et la partie de rupture (29) de la partie de prélèvement (B) présente une patte de saisie latérale (31), qui s'étend jusqu'à la partie de bord (3) du capuchon de fermeture.
  2. Capuchon de fermeture selon la revendication 1, caractérisé en ce que la partie de fermeture (14) de la partie d'injection (A) présente un évidement (15), dans lequel la membrane à étanchéité intrinsèque (16) est insérée à déclic.
  3. Capuchon de fermeture selon la revendication 1 ou 2, caractérisé en ce que la partie de fermeture (14) de la partie d'injection (A) présente un bord saillant vers l'intérieur (35), qui fixe la membrane à étanchéité intrinsèque (16) par serrage dans l'évidement (15).
  4. Capuchon de fermeture selon l'une quelconque des revendications 1 à 3, caractérisé en ce que la partie de fermeture (14) de la partie d'injection (A) avec la membrane à étanchéité intrinsèque (16) est réalisée de telle manière que, lors de l'introduction de la tige conique d'une aiguille d'injection, la membrane soit comprimée en direction axiale dans l'évidement (15), de telle façon que la membrane soit ouverte.
  5. Capuchon de fermeture selon l'une quelconque des revendications 1 à 4, caractérisé en ce que l'évidement (15) de la partie de fermeture (14) de la partie d'injection (A) présente une première section cylindrique (17), qui se raccorde à la partie de couvercle (2), et présente une deuxième section cylindrique (18) se raccordant à la première section cylindrique, qui a un plus grand diamètre intérieur que la première section cylindrique.
  6. Capuchon de fermeture selon la revendication 5, caractérisé en ce que la membrane à étanchéité intrinsèque (16) présente une partie annulaire (19), qui est disposée dans la deuxième section cylindrique (18) de l'évidement (15), et présente une partie en forme de plateau (21) se raccordant à la partie annulaire par un col intermédiaire (20), qui est disposée dans la première section cylindrique (17).
  7. Capuchon de fermeture selon la revendication 6, caractérisé en ce que la partie en forme de plateau (21) de la membrane à étanchéité intrinsèque (16) présente un creux en forme de cuvette (22).
  8. Capuchon de fermeture selon l'une quelconque des revendications 1 à 7, caractérisé en ce que la partie de raccordement (6) de la partie d'injection (A) présente un filet extérieur (8).
  9. Capuchon de fermeture selon l'une quelconque des revendications 1 à 8, caractérisé en ce que la membrane perforable (33) de la partie de prélèvement (B) est insérée par déclic dans l'évidement (28).
  10. Capuchon de fermeture selon la revendication 9, caractérisé en ce que la partie de fermeture (32) de la partie de prélèvement (B) présente un bord saillant vers l'intérieur (34), qui fixe la membrane à étanchéité intrinsèque (33) par serrage dans l'évidement (28).
  11. Récipient, en particulier bouteille BFS, munie d'un capuchon de fermeture (1) selon l'une quelconque des revendications 1 à 10.
EP08707528.9A 2007-02-03 2008-02-04 Capuchon de fermeture pour un récipient destiné à recevoir des liquides médicaux et récipient destiné à recevoir des liquides médicaux Active EP2114345B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200710005407 DE102007005407A1 (de) 2007-02-03 2007-02-03 Verschlusskappe für ein Behältnis zur Aufnahme von medizinischen Flüssigkeiten und Behältnis zur Aufnahme von medizinischen Flüssigkeiten
PCT/EP2008/000851 WO2008095665A1 (fr) 2007-02-03 2008-02-04 Capuchon de fermeture pour un récipient destiné à recevoir des liquides médicaux et récipient destiné à recevoir des liquides médicaux

Publications (2)

Publication Number Publication Date
EP2114345A1 EP2114345A1 (fr) 2009-11-11
EP2114345B1 true EP2114345B1 (fr) 2016-12-07

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EP08707528.9A Active EP2114345B1 (fr) 2007-02-03 2008-02-04 Capuchon de fermeture pour un récipient destiné à recevoir des liquides médicaux et récipient destiné à recevoir des liquides médicaux

Country Status (12)

Country Link
US (1) US9095500B2 (fr)
EP (1) EP2114345B1 (fr)
JP (1) JP5563310B2 (fr)
KR (1) KR101462198B1 (fr)
CN (1) CN101600411B (fr)
AU (1) AU2008213344B2 (fr)
BR (1) BRPI0807070B8 (fr)
CA (1) CA2677286C (fr)
DE (1) DE102007005407A1 (fr)
MX (1) MX2009008272A (fr)
WO (1) WO2008095665A1 (fr)
ZA (1) ZA200904680B (fr)

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JP2010517607A (ja) 2010-05-27
CN101600411A (zh) 2009-12-09
EP2114345A1 (fr) 2009-11-11
BRPI0807070B1 (pt) 2018-10-02
CA2677286A1 (fr) 2008-08-14
BRPI0807070A2 (pt) 2014-04-08
CN101600411B (zh) 2014-11-05
ZA200904680B (en) 2010-04-28
AU2008213344B2 (en) 2013-08-29
CA2677286C (fr) 2015-04-07
US9095500B2 (en) 2015-08-04
KR20090113278A (ko) 2009-10-29
WO2008095665A1 (fr) 2008-08-14
KR101462198B1 (ko) 2014-11-17
JP5563310B2 (ja) 2014-07-30
US20100059474A1 (en) 2010-03-11
MX2009008272A (es) 2009-08-12
BRPI0807070B8 (pt) 2021-06-22
DE102007005407A1 (de) 2008-08-07
AU2008213344A1 (en) 2008-08-14

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