EP2114345B1 - Closure cap for a container for receiving medical liquids, and container for receiving medical liquids - Google Patents

Closure cap for a container for receiving medical liquids, and container for receiving medical liquids Download PDF

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Publication number
EP2114345B1
EP2114345B1 EP08707528.9A EP08707528A EP2114345B1 EP 2114345 B1 EP2114345 B1 EP 2114345B1 EP 08707528 A EP08707528 A EP 08707528A EP 2114345 B1 EP2114345 B1 EP 2114345B1
Authority
EP
European Patent Office
Prior art keywords
part
closure cap
recess
closure
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP08707528.9A
Other languages
German (de)
French (fr)
Other versions
EP2114345A1 (en
Inventor
Torsten Brandenburger
Gerhard Greier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Kabi Deutschland GmbH
Original Assignee
Fresenius Kabi Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE200710005407 priority Critical patent/DE102007005407A1/en
Application filed by Fresenius Kabi Deutschland GmbH filed Critical Fresenius Kabi Deutschland GmbH
Priority to PCT/EP2008/000851 priority patent/WO2008095665A1/en
Publication of EP2114345A1 publication Critical patent/EP2114345A1/en
Application granted granted Critical
Publication of EP2114345B1 publication Critical patent/EP2114345B1/en
Application status is Active legal-status Critical
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096Combination of a vial and a syringe for transferring or mixing their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/1412Containers with closing means, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/1412Containers with closing means, e.g. caps
    • A61J1/1418Threaded type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/1412Containers with closing means, e.g. caps
    • A61J1/1431Permanent type, e.g. welded or glued
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/18Arrangements for indicating condition of container contents, e.g. sterile condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202Separating means
    • A61J1/2044Separating means having slits
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/002Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Description

  • The invention relates to a closure cap for a container for holding medical fluids, in particular an infusion or transfusion container, which has a cover part and a peripheral part. Moreover, the invention relates to a container for receiving medical fluids, in particular a BFS container, with such a cap.
  • As a blow-fill-seal method (BFS method), a method is known in which containers, such as bottles of extruded PE or PP, in a single operation sterile and pyrogen-free blown into a desired shape and immediately after cooling with a sterile filling aseptically filled and hermetically sealed. The containers produced by the bubble-fill-seal method, in particular bottles, are also referred to as BFS containers.
  • When the known BFS containers are used for receiving sterile, medical liquids, for example infusion solutions, the containers require a closure cap system which allows a transfer of the infusion solution by means of an infusion device to the patient. The addition of medication to the infusion solution should also be possible.
  • The closest prior art DE 10 2004 051 300 B3 thus opens a cap, the connecting parts of injection part and removal part have a break-off at a ring break zone.
  • From the WO 96/23545 an infusion bag with an injection part and a removal part is known. The dispensing part is for removing the infusion solution by means of a spike, while the injection part is used for supplying a drug by means of a syringe having a thin cannula (needle). The injection part comprises a tubular connection part which is closed by a protective cap designed as a break-off part. In the connection part sits a self-sealing membrane (septum), which is pierced by the cannula of the injection syringe. A pierceable membrane in the connector prevents the septum from contacting the solution prior to use of the infusion bag. The sampling part does not have a self-sealing septum. The from the WO 96/23545 known injection and withdrawal part is intended to be welded into an infusion bag.
  • In practice, the known Zuspritzteile have proven. From the use of an injection needle for injecting an active ingredient, however, there are disadvantages. First, there is a risk that the connection between the injection needle and the septum due to an unintentional pull on the syringe or an overpressure inside the bag dissolves. On the other hand, there is an increased risk of injury to the nursing staff through the injection needle. Also, the infusion bag, in which the injection part is welded, can be damaged by improper handling by the needle. The addition of a viscous drug is more difficult due to the small cross section of the needle beyond. Incidentally, the supply of a liquid agent due to the small cross section of the needle requires a relatively long time.
  • For connection of medical devices, conical connections with a conical shank and a conical sleeve are known in medical technology whose conical surfaces are normalized. The non-lockable conical connections with normalized conical surfaces are referred to as luer connectors and the lockable conical connections as luer lock connectors. Tapered Luer or Luer-Lock connectors are referred to as male connectors and tapered sleeve connectors as female connectors.
  • The DE 103 48 016 A1 describes a connector to be welded into an infusion bag that allows the injection of an agent by means of a conventional luer-lock syringe that does not have an injection needle. The known connector has a connection part which has a channel-shaped recess in which a self-sealing membrane is arranged. A break-off part, which is connected to the connecting part, closes the channel-shaped recess. Above the membrane, the connecting part is designed as a connecting piece with an inner cone and an outer thread, wherein the membrane for sealingly receiving the Taper shank of a syringe is slotted. The connector is composed of an upper and a lower section, between which the self-sealing membrane is clamped.
  • From the DE 20 2004 003 267 U1 a closure cap for a BFS container is known, which has a lid part and a peripheral part, wherein in the lid part a slotted membrane is used, which allows the imports of the spike of an infusion device. The slotted membrane sits flush in the cover part of the cap.
  • The invention has for its object to provide a cap for a container for receiving medical fluids, in particular a BFS container, which allows the injection of a liquid without the use of an injection cannula. Moreover, it is an object of the invention to provide a container for receiving medical fluids, in particular a BFS container, which allows the injection of a liquid without the use of an injection cannula.
  • The solution of these objects is achieved according to the invention with the features specified in the claims 1 and 11. Preferred embodiments of the invention are subject of the dependent claims.
  • The closure cap according to the invention for a container for holding medical fluids, in particular a BFS container for holding an infusion solution, has a cover part and a rim part, wherein an injection part for injecting a medical fluid is arranged in the cover part.
  • The injection part has an outwardly pointing connection part with a conical recess for sealingly receiving the conical shaft of a needleless injection syringe and an inwardly pointing closure part which has a self-sealing membrane for closing the recess of the connection part. The self-sealing membrane is slotted so that the cone shank of the syringe can be easily inserted. It is advantageous that the closure cap according to the invention with the exception of the self-sealing membrane is formed in one piece. As a result, the production of the cap in large quantities at low cost is possible.
  • In a preferred embodiment of the closure cap, the closure part of the injection part has a recess in which the self-sealing membrane is inserted in a snap-fit manner. Preferably, the self-sealing membrane is clamped by an inwardly projecting edge of the closure member in the recess. Instead of an inwardly projecting edge which extends over the entire circumference of the closure part, the closure part can also have distributed circumferentially arranged hooks for clamping fixation of the self-sealing membrane.
  • In a further preferred embodiment of the invention, the recess of the closure part has a first cylindrical portion adjoining the lid portion and a second cylindrical portion adjoining the first cylindrical portion, the first cylindrical portion having a smaller inner diameter than the second cylindrical portion Section has.
  • A preferred embodiment of the closure cap provides that the self-sealing membrane has an annular portion which is arranged in the second cylindrical portion of the recess with the larger inner diameter, and has a plate-shaped portion adjoining the annular portion via a central web, which in the first cylindrical portion having the smaller inner diameter is arranged. As a result, the self-sealing membrane has a secure hold in the recess of the closure part.
  • Preferably, the plate-shaped portion of the self-sealing membrane has a trough-shaped depression. The trough-shaped depression ensures, on the one hand, that the cone shank of the syringe is securely guided and, on the other hand, ensures that the membrane seals securely after pulling out the conical shank. It has been shown in experiments that the special design of the membrane for the immediate Resealing is crucial, with increasing internal pressure in the package, the sealing of the membrane is still increased.
  • In a particularly preferred embodiment, the closure part of the injection part is formed with the self-sealing membrane such that upon insertion of the conical shaft of the injection syringe, the membrane is compressed in the recess in the axial direction. As a result, the membrane opens when inserting the conical shaft. The self-sealing membrane is on the one hand sufficiently fixed in the recess of the closure part, but on the other hand so freely movable that the membrane can be compressed in the axial direction during insertion of the conical shaft. The height of the membrane is reduced, i. the top of the diaphragm loses its contact with the contact surface of the recess of the closure part.
  • The closure part of the injection part can be designed either for a luer syringe or a luer lock syringe. Preferably, the connecting part of the injection part has an external thread, so that a Luer-lock connection with the syringe is possible.
  • For aseptic closure of the self-sealing membrane, the connection part is closed with a break-off part, which is connected to the upper end of the connection part via a ring-breaking zone. After breaking off the break-off part, the self-sealing membrane is exposed, so that the cone shank of the syringe can be inserted.
  • To improve the handling, the break-off part has a lateral grip tab which extends up to the edge part of the cover part of the closure cap.
  • In addition to the injection part, the closure cap according to the invention also has a removal part for removing a medical liquid with a spike. The extraction part also has an outwardly facing fitting with a recess into which a spike is inserted and an inwardly facing closure part which is closed by a pierceable membrane.
  • The pierceable membrane is inserted snapping into a recess of the closure part of the removal part. Preferably, the membrane is clamped by an inwardly projecting edge of the closure part. The connection part of the removal part is also closed with a break-off part, which is connected to the upper end of the connection part via a ring-break zone. The break-off part of the removal part also has a lateral grip tab which extends up to the edge part of the cover part.
  • The container according to the invention, in particular infusion or transfusion container, which is preferably designed as a bottle, is closed with the closure cap described above.
  • In the following an embodiment of the invention will be explained in more detail with reference to the drawings.
  • Show it:
  • Fig. 1
    An embodiment of the closure cap according to the invention,
    Fig. 2
    the cap of FIG. 1 in the side view,
    Fig. 3
    a section through the cap of FIG. 1 along the line III-III in an enlarged view,
    Fig. 4 A and Fig. 4 B
    the cap before and after retraction of the conical shank of a hypodermic syringe,
    Fig. 4C
    a section of FIG. 4B in an enlarged view,
    Fig. 5
    the cap of Fig. 1 in a cut view and
    Fig. 6
    An embodiment of a container according to the invention with the closure cap according to the invention.
  • The Figures 1 and 2 show the closure cap according to the invention in the side view which has an injection part A and a removal part B. With the exception of the self-sealing or puncturable membrane, the closure cap is a one-piece plastic part which can be produced inexpensively in large quantities.
  • The closure cap 1 has a lid part 2 and a rim part 3. The lid member 2 has an outer portion 4 and an inner portion 5 projecting outwardly. From the inner outwardly projecting portion 5 has a connecting part 6 for inserting the conical shank of a needleless injection syringe to the outside ( Fig. 3 ). The connecting part 6 has a conical recess 7 for sealingly receiving the conical shaft of the syringe and an external thread 8. The conical recess 7 and the external thread 8 are formed such that a commercially available Luer-lock syringe can be connected to the connecting part.
  • The connection part 6 is closed with a break-off part 9, which is connected via a ring breaking zone 10 to the upper end of the connecting part. The break-off part 9 has a round cap 11, to which a lateral tab 12 adjoins a narrow web 12, which extends down to the edge part of the cover part. The grip tab 13 is designed such that it does not extend laterally beyond the closure cap.
  • From the central portion 5 of the lid part 2, a closure part 14 has inwardly, which has a recess 15. In the recess 15 of the closure part 14, a self-sealing membrane 16 is inserted, which sits snapping into the recess.
  • The recess 15 of the closure part 14 has an upper cylindrical portion 17, which adjoins the central portion 5 of the lid part 2. The upper cylindrical portion 17 is followed by a lower cylindrical portion 18 having a larger inner diameter than the upper cylindrical portion 17. The Self-sealing membrane 16 has correspondingly a lower annular portion 19 with a larger outer diameter, which sits in the lower cylindrical portion 18 of the recess 15. Adjoining the annular section 19 of the membrane 16, via a central web 20, is an upper dish-shaped section 21 with a smaller outside diameter, which sits snugly in the upper cylindrical section 17 of the recess 15. The closure part has an inwardly projecting edge 35, which fixes the membrane 16 in a clamping manner. The dish-shaped portion 21 of the membrane 16 has a trough-shaped recess 22, which is provided with one or more slots 23, for example, is slotted crosswise.
  • The edge part 3 of the closure cap 1 has a lower bead-shaped edge 24, which has a circumferential groove 25 on the underside. The cap can be placed on a bottle, wherein the upper edge of the bottle neck engages in the groove 25 of the bead-shaped edge 24 of the cap.
  • Hereinafter, the operation of the injection part A of the cap with reference to the FIGS. 4A, 4B and 4C described.
  • For injecting a liquid, for example a medicament with a needleless injection syringe, the break-off part 9 is first broken off from the connection part 6 by lateral pivoting of the handle bottle 13. Thus, the self-sealing membrane 16 is exposed. Then, the conical taper shank 36 of a needleless injection syringe 26 is inserted into the conical recess 7 of the connection part 6. The conical shaft 36 presses on the plate-shaped portion 22 of the self-sealing membrane 16, whereby the membrane is pressed together ( FIG. 4C ). As a result, the middle web 20 of the membrane 16 presses inwards, wherein the plate-shaped portion 22 is opened in the region of the slots 23. The drug can now be injected.
  • In addition to the injection part A, the closure cap also has a removal part B. The injection and removal part A, B are laterally the axis of the closure cap arranged side by side in the middle section 5 of the cover part 2 of the closure cap. The removal part B has the same construction as the injection part A (FIG. Fig. 5 ).
  • The removal part B has a connecting part 27, which points outwards from the middle section 5 of the cover part 2 and has a recess 28 for insertion of the spike of an infusion device. The recess 28 of the connecting part 27 is closed by a break-off part 29, which is connected via a ring breaking zone 30 to the upper end of the connecting part. The break-off part 30 again has a lateral grip bottle 31, which is designed like the grip tab of the break-off part of the injection part. From the central portion 5 of the cover part 2 has a closure member 32 down, in which a pierceable by a spike membrane 33 is fixed by clamping. The membrane 33 is held by an inwardly projecting edge 34 of the closure member 32. After breaking off the break-off part 29, the membrane 33 is exposed, which is pierced by the spike. With the spike, a liquid can be removed.
  • FIG. 6 shows the closure cap according to the invention together with a container according to the invention, which is a BFS bottle in the present embodiment.
  • The cap 1 is firmly seated on the bottle neck 37 of the bottle 38, which is filled with an infusion solution, for example. Since the bottleneck is not closed in the head area, but open, the liquid is in direct contact with the cap. Thus, it is possible to inject a drug with a needleless injection syringe. The closure cap is preferably designed as a screw cap, which is screwed onto the bottle neck 37. But it is also possible to weld the cap with the bottleneck.

Claims (11)

  1. Closure cap for a container with an interior for receiving medical liquids, in particular a BFS container, which closure cap has a cover part (2) and an edge part (3), wherein
    - an injection part (A) for injecting a medical liquid is arranged in the cover part (2), said injection part (A) having an outwardly directed connection part (6), with a conical recess (7) for sealingly receiving the cone stem of a needleless injection syringe, and an inwardly directed closure part (14) which has a self-sealing membrane (16) for closing the recess of the connection part, which self-sealing membrane (16) is slit, wherein
    the connection part (6) of the injection part (A) is closed with a break-off part (9) which is connected to the upper end of the connection part (6) via an annular break zone (10), and the break-off part (9) has a lateral grip tab (13) extending as far as the edge part (3) of the closure cap, and
    - a withdrawal part (B) for withdrawing a medical liquid using a spike is arranged in the cover part (2), said withdrawal part (B) having an outwardly directed connection part (27), with a recess (28) for receiving a spike, and an inwardly directed closure part (32) which has a pierceable membrane (33) for closing the recess of the connection part, wherein
    the connection part (27) of the withdrawal part (B) is closed with a break-off part (29), which is connected to the upper end of the connection part (27) via an annular break-off zone (30), and the break-off part (29) of the withdrawal part (B) has a lateral grip tab (31) extending as far as the edge part (3) of the closure cap.
  2. Closure cap according to Claim 1, characterized in that the closure part (14) of the injection part (A) has a recess (15), in which the self-sealing membrane (16) is inserted with snap-fit engagement.
  3. Closure cap according to Claim 1 or 2, characterized in that the closure part (14) of the injection part (A) has an inwardly projecting edge (35), which fixes the self-sealing membrane (16) in the recess (15) in a clamping manner.
  4. Closure cap according to one of Claims 1 to 3, characterized in that the closure part (14) of the injection part (A) is formed with the self-sealing membrane (16) in such a way that, when the cone stem of an injection syringe is inserted, the membrane is compressed in axial direction in the recess (15), such that the membrane is opened.
  5. Closure cap according to one of Claims 1 to 4, characterized in that the recess (15) of the closure part (14) of the injection part (A) has a first cylindrical portion (17), which adjoins the cover part (2), and a second cylindrical portion (18), which adjoins the first cylindrical portion and which has a greater internal diameter than the first cylindrical portion.
  6. Closure cap according to Claim 5, characterized in that the self-sealing membrane (16) has an annular portion (19), which is arranged in the second cylindrical portion (18) of the recess (15), and a plate-shaped portion (21), which adjoins the annular portion via a central web (20) and is arranged in the first cylindrical portion (17).
  7. Closure cap according to Claim 6, characterized in that the plate-shaped portion (21) of the self-sealing membrane (16) has a cup-shaped depression (22).
  8. Closure cap according to one of Claims 1 to 7, characterized in that the connection part (6) of the injection part (A) has an outer thread (8).
  9. Closure cap according to one of Claims 1 to 8, characterized in that the pierceable membrane (33) of the withdrawal part (B) is inserted into the recess (28) with snap-fit engagement.
  10. Closure cap according to Claim 9, characterized in that the closure part (32) of the withdrawal part (B) has an inwardly projecting edge (34), which fixes the pierceable membrane (33) in the recess (28) in a clamping manner.
  11. Container, in particular a BFS bottle, with a closure cap (1) according to one of Claims 1 to 10.
EP08707528.9A 2007-02-03 2008-02-04 Closure cap for a container for receiving medical liquids, and container for receiving medical liquids Active EP2114345B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE200710005407 DE102007005407A1 (en) 2007-02-03 2007-02-03 Cap for a container for holding medical fluids and container for receiving medical fluids
PCT/EP2008/000851 WO2008095665A1 (en) 2007-02-03 2008-02-04 Closure cap for a container for receiving medical liquids, and container for receiving medical liquids

Publications (2)

Publication Number Publication Date
EP2114345A1 EP2114345A1 (en) 2009-11-11
EP2114345B1 true EP2114345B1 (en) 2016-12-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP08707528.9A Active EP2114345B1 (en) 2007-02-03 2008-02-04 Closure cap for a container for receiving medical liquids, and container for receiving medical liquids

Country Status (12)

Country Link
US (1) US9095500B2 (en)
EP (1) EP2114345B1 (en)
JP (1) JP5563310B2 (en)
KR (1) KR101462198B1 (en)
CN (1) CN101600411B (en)
AU (1) AU2008213344B2 (en)
BR (1) BRPI0807070A2 (en)
CA (1) CA2677286C (en)
DE (1) DE102007005407A1 (en)
MX (1) MX2009008272A (en)
WO (1) WO2008095665A1 (en)
ZA (1) ZA200904680B (en)

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CN101600411A (en) 2009-12-09
AU2008213344A1 (en) 2008-08-14
MX2009008272A (en) 2009-08-12
JP5563310B2 (en) 2014-07-30
US20100059474A1 (en) 2010-03-11
AU2008213344B2 (en) 2013-08-29
DE102007005407A1 (en) 2008-08-07
ZA200904680B (en) 2010-04-28
CA2677286C (en) 2015-04-07
EP2114345A1 (en) 2009-11-11
CN101600411B (en) 2014-11-05
WO2008095665A1 (en) 2008-08-14
BRPI0807070A2 (en) 2014-04-08
CA2677286A1 (en) 2008-08-14
KR20090113278A (en) 2009-10-29
US9095500B2 (en) 2015-08-04
JP2010517607A (en) 2010-05-27
KR101462198B1 (en) 2014-11-17

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