EE04416B1 - a1L- agonistide kasutamine uriiniinkontinentsuse raviks - Google Patents
a1L- agonistide kasutamine uriiniinkontinentsuse raviksInfo
- Publication number
- EE04416B1 EE04416B1 EE9700267A EE9700267A EE04416B1 EE 04416 B1 EE04416 B1 EE 04416B1 EE 9700267 A EE9700267 A EE 9700267A EE 9700267 A EE9700267 A EE 9700267A EE 04416 B1 EE04416 B1 EE 04416B1
- Authority
- EE
- Estonia
- Prior art keywords
- agonists
- treatment
- urinary incontinence
- incontinence
- urinary
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19514579A DE19514579A1 (de) | 1995-04-20 | 1995-04-20 | Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz |
PCT/EP1996/001568 WO1996032939A1 (de) | 1995-04-20 | 1996-04-13 | VERWENDUNG VON α1L-AGONISTEN ZUR BEHANDLUNG DER HARNINKONTINENZ |
Publications (2)
Publication Number | Publication Date |
---|---|
EE9700267A EE9700267A (et) | 1998-06-15 |
EE04416B1 true EE04416B1 (et) | 2005-02-15 |
Family
ID=7759982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EE9700267A EE04416B1 (et) | 1995-04-20 | 1996-04-13 | a1L- agonistide kasutamine uriiniinkontinentsuse raviks |
Country Status (31)
Country | Link |
---|---|
US (4) | US6268389B1 (xx) |
EP (2) | EP1285653A1 (xx) |
JP (2) | JP3379960B2 (xx) |
KR (1) | KR19990007985A (xx) |
CN (1) | CN1119148C (xx) |
AR (1) | AR002043A1 (xx) |
AU (1) | AU719710B2 (xx) |
BG (1) | BG64116B1 (xx) |
BR (1) | BR9608049A (xx) |
CA (1) | CA2214338C (xx) |
CZ (1) | CZ327197A3 (xx) |
DE (2) | DE19514579A1 (xx) |
EE (1) | EE04416B1 (xx) |
ES (1) | ES2279521T3 (xx) |
HR (1) | HRP960187A2 (xx) |
HU (1) | HUP9801599A3 (xx) |
IL (1) | IL117956A (xx) |
MX (1) | MX9707570A (xx) |
NO (1) | NO974821L (xx) |
NZ (1) | NZ307509A (xx) |
PE (1) | PE44297A1 (xx) |
PL (1) | PL184881B1 (xx) |
RU (2) | RU2230061C2 (xx) |
SK (1) | SK138097A3 (xx) |
TR (1) | TR199701212T1 (xx) |
TW (1) | TW403739B (xx) |
UA (1) | UA62913C2 (xx) |
UY (1) | UY24206A1 (xx) |
WO (1) | WO1996032939A1 (xx) |
YU (1) | YU24496A (xx) |
ZA (1) | ZA963131B (xx) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19514579A1 (de) * | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz |
SG72827A1 (en) * | 1997-06-23 | 2000-05-23 | Hoffmann La Roche | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives |
US6503935B1 (en) | 1998-08-07 | 2003-01-07 | Abbott Laboratories | Imidazoles and related compounds as α1A agonists |
GB9906192D0 (en) | 1999-03-18 | 1999-05-12 | Medical Res Council | Photoreleasable compounds |
US6323231B1 (en) | 2000-02-17 | 2001-11-27 | Abbott Laboratories | Use of α1A adrenoceptor agonists with α1B and α1D antagonism for the treatment of stress urinary incontinence |
DE10150312A1 (de) * | 2000-10-14 | 2002-07-04 | Boehringer Ingelheim Pharma | Neue m-Amino-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz |
US6602897B2 (en) | 2000-10-14 | 2003-08-05 | Boehringer Ingelheim Pharma Kg | m-Amino-phenylimino-imidazolidine derivatives for treating urinary incontinence |
GB0030580D0 (en) * | 2000-12-15 | 2001-01-31 | Medicare Man Consultancy Ltd | Composition and method |
DE10104369A1 (de) * | 2001-02-01 | 2002-08-08 | Boehringer Ingelheim Pharma | Verwendung von 2-Amino-(4-hydroxy-2-methansulfonamidophenyl)ethanol zur Behandlung der Harninkontinenz |
US6660772B2 (en) | 2001-02-01 | 2003-12-09 | Boehringer Ingelheim Pharma Kg | Use of 2-amino-1-(4-hydroxy-2-methanesulfonamidophenyl)ethanol for treating urinary incontinence |
DE10106214A1 (de) * | 2001-02-10 | 2002-08-14 | Boehringer Ingelheim Pharma | Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz |
US20020169193A1 (en) * | 2001-02-10 | 2002-11-14 | Pascale Pouzet | Alkylphenyliminoimidazolidine derivatives for treating urinary incontinence |
GB0114008D0 (en) * | 2001-06-08 | 2001-08-01 | Perry Robert E | New therapautic use |
US6455557B1 (en) | 2001-11-28 | 2002-09-24 | Elan Pharmaceuticals, Inc. | Method of reducing somnolence in patients treated with tizanidine |
US20040220240A1 (en) * | 2001-11-28 | 2004-11-04 | Pellegrini Cara A. | Method of increasing the extent of absorption of tizanidine |
US6703409B2 (en) | 2002-01-31 | 2004-03-09 | Boehringer Ingelheim Pharma Gmbh & Co Kg | 2′-Halo-3′,5′-dialkoxyphen-1′-yl-imino-2-imidazolidine and the use thereof as a drug |
EP1333028A1 (en) * | 2002-01-31 | 2003-08-06 | Boehringer Ingelheim Pharma GmbH & Co.KG | 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence |
EP1501826B1 (en) * | 2002-02-01 | 2006-09-27 | F. Hoffman-la Roche AG | Substituted indoles as alpha-1 agonists |
DE10352132A1 (de) * | 2003-11-04 | 2005-06-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmazeutische Zusammensetzung aus einem Beta-3-Adrenozeptor-Agonisten und einem Alpha Agonisten |
ES2510546T3 (es) * | 2007-02-02 | 2014-10-21 | F. Hoffmann-La Roche Ag | Nuevas 2-aminooxazolinas como ligandos TAAR1 para trastornos del SNC |
ES2525229T3 (es) * | 2007-02-15 | 2014-12-19 | F. Hoffmann-La Roche Ag | 2-aminooxazolinas como ligandos de TAAR1 |
AU2008281877A1 (en) * | 2007-08-02 | 2009-02-05 | F. Hoffmann-La Roche Ag | The use of benzamide derivatives for the treatment of CNS disorders |
CA2696315A1 (en) * | 2007-08-15 | 2009-02-19 | Allergan, Inc. | Heterocyclyl substituted fused carbocyles useful in the treatment of conditions such as glaucoma and pain |
BRPI0815500A2 (pt) * | 2007-08-15 | 2017-05-30 | Allergan Inc | compostos terapêuticos, bem como seus usos |
JP4168086B1 (ja) * | 2008-04-16 | 2008-10-22 | 国立大学法人福井大学 | イミダゾリン誘導体 |
MX2011000464A (es) * | 2008-07-24 | 2011-03-01 | Hoffmann La Roche | Derivados de 4,5-dihidro-oxazol-2-ilo. |
US8242153B2 (en) * | 2008-07-24 | 2012-08-14 | Hoffmann-La Roche Inc. | 4,5-dihydro-oxazol-2YL derivatives |
GB2466622A (en) * | 2008-12-23 | 2010-06-30 | Trinity College Dublin | Alpha2-Adrenoceptor Ligands |
US20100311798A1 (en) * | 2009-06-05 | 2010-12-09 | Decoret Guillaume | 2-aminooxazolines as taar1 ligands |
US8354441B2 (en) * | 2009-11-11 | 2013-01-15 | Hoffmann-La Roche Inc. | Oxazoline derivatives |
US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
WO2012008565A1 (ja) * | 2010-07-16 | 2012-01-19 | 日本ケミファ株式会社 | イミダゾリン誘導体 |
MA34591B1 (fr) | 2010-10-06 | 2013-10-02 | Glaxosmithkline Llc | Dérivés de benzimidazole utilisés comme inhibiteurs de pi3 kinase |
WO2015152196A1 (ja) * | 2014-03-31 | 2015-10-08 | 東レ株式会社 | イミダゾリン誘導体及びその医薬用途 |
PL3430010T3 (pl) | 2016-03-17 | 2020-11-16 | F. Hoffmann-La Roche Ag | Pochodna 5-etylo-4-metylopirazolo-3-karboksyamidu wykazująca aktywność jako agonista taar |
Family Cites Families (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE71554C (de) * | B. BROCKHUES, in Firma BROCKHUES & ClE, in Köln a. Rh | Leicht transportable Nothlaschung für Schienenbrüche | ||
US2899426A (en) * | 1959-08-11 | Synthesis of l | ||
US2744910A (en) * | 1955-06-27 | 1956-05-08 | Bristol Lab Inc | 2-(ortho-benzylbenzyl)-imidazoline and acid addition salts |
US2915431A (en) * | 1956-07-17 | 1959-12-01 | Lab Robert & Carriere Sa Des | 2-(2'-isopropyl-4'-chloro-5'-methyl)-phenoxymethyl-2-imidazoline and its pharmaceutical uses |
US3081222A (en) * | 1960-03-11 | 1963-03-12 | Us Rubber Co | Fungicides |
US3202660A (en) | 1961-10-09 | 1965-08-24 | Boehringer Sohn Ingelheim | Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes |
AT285599B (de) | 1968-06-21 | 1970-11-10 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von neuen trisubstituierten 2-Arylaminoimidazolinen und ihren Salzen |
BE754935A (fr) * | 1969-08-13 | 1971-02-17 | Hoechst Ag | 2-(thienyl-3'-amino)-1,3-diazacycloalcenes et leur preparation |
DE2316377C3 (de) | 1973-04-02 | 1978-11-02 | Lentia Gmbh, Chem. U. Pharm. Erzeugnisse - Industriebedarf, 8000 Muenchen | Verfahren zur Herstellung von 2-Phenyl-amino-2-imidazolin-Derivaten und von deren Salzen |
FR2269341B1 (xx) * | 1974-04-30 | 1978-07-28 | Castaigne Sa | |
MTP837B (en) * | 1977-11-07 | 1979-10-22 | Hoffman La Roche And Co Aktien | Derivatives 2 finino-imidazolidire |
DE2806775A1 (de) * | 1978-02-17 | 1979-08-30 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
DE2806811A1 (de) * | 1978-02-17 | 1979-08-23 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben |
DE2811847A1 (de) | 1978-03-17 | 1979-09-20 | Lentia Gmbh | Neue arylaminoimidazolinderivate, deren herstellung und verwendung als arzneimittel |
US4226713A (en) | 1978-04-24 | 1980-10-07 | Goldberg Jack M | Diagnostic agents |
US4262005A (en) * | 1978-05-31 | 1981-04-14 | The Boots Company Limited | Compounds, compositions and methods for controlling pests |
US4323570A (en) * | 1978-11-15 | 1982-04-06 | Beiersdorf Aktiengesellschaft | Substituted aminopyrimidines |
DE2854659A1 (de) * | 1978-12-18 | 1980-07-10 | Boehringer Sohn Ingelheim | Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
US4226773A (en) * | 1979-05-07 | 1980-10-07 | Abbott Laboratories | Pyrazolyl amino imidazolines as diuretic agents |
DE2949287A1 (de) | 1979-12-07 | 1981-06-11 | C.H. Boehringer Sohn, 6507 Ingelheim | Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
US4287201A (en) * | 1980-03-03 | 1981-09-01 | Merck & Co., Inc. | Anovulatory method and chicken feed compositions |
DE3168754D1 (en) * | 1980-07-09 | 1985-03-21 | Beecham Group Plc | Clonidine derivatives useful in the treatment of diarrhoea |
EP0070084A3 (en) * | 1981-04-24 | 1983-02-16 | Beecham Group Plc | Imidazoline derivatives |
DE3133886A1 (de) | 1981-08-27 | 1983-03-17 | Bayer Ag, 5090 Leverkusen | 2-arylazo-2-imidazoline, acylderivate derselben, verfahren zu ihrer herstellung und die verwendung zur bekaempfung von ekto- und/oder endoparasiten |
US4461904A (en) * | 1981-11-20 | 1984-07-24 | Alcon Laboratories, Inc. | 2-(Trisubstituted phenylimino)-imidazolines |
US4517199A (en) * | 1981-11-20 | 1985-05-14 | Alcon Laboratories, Inc. | Method for lowering intraocular pressure using phenylimino-imidazoles |
CA1201066A (en) * | 1981-11-20 | 1986-02-25 | Alcon Laboratories, Inc. | N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure |
US4644007A (en) * | 1981-11-20 | 1987-02-17 | Alcon Laboratories, Inc. | 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods |
FR2521140A1 (fr) | 1982-02-05 | 1983-08-12 | Synthelabo | Derives d'imidazolidine, leur preparation et leur application en therapeutique |
GB8304593D0 (en) * | 1983-02-18 | 1983-03-23 | Beecham Group Plc | Amidines |
GB8333835D0 (en) * | 1983-12-20 | 1984-02-01 | Beecham Group Plc | Compounds |
EP0236636A3 (en) * | 1986-02-07 | 1988-12-07 | Alcon Laboratories, Inc. | Use of clonidine derivatives for the preparation of ocular hemostatic agents |
US4587257A (en) * | 1984-12-14 | 1986-05-06 | Alcon Laboratories, Inc. | Control of ocular bleeding using clonidine derivatives |
US4861904A (en) * | 1986-04-17 | 1989-08-29 | Agency Of Industrial Science And Technology | Schiff base metal complex compounds, and organometallic ultrathin film composed thereof and oxygen separation films composed thereof |
GB8610909D0 (en) * | 1986-05-03 | 1986-06-11 | Beecham Group Plc | Compounds |
US4861189A (en) * | 1987-02-26 | 1989-08-29 | Kajima Corporation | System for paving inclined and/or curved surfaces |
US4801617A (en) * | 1987-04-06 | 1989-01-31 | Leclerc Gerard | Iminoimidazolidines useful in lowering intraocular pressure |
DE3712385A1 (de) * | 1987-04-11 | 1988-10-27 | Boehringer Ingelheim Kg | 2-(phenylimino)imidazolidine |
JPH078795B2 (ja) * | 1989-09-06 | 1995-02-01 | 日立化成工業株式会社 | 排尿障害治療剤 |
US5130441A (en) * | 1990-02-06 | 1992-07-14 | Allergan, Inc. | Method for producing amino-2-imidazoline derivatives |
US5237072A (en) * | 1990-02-06 | 1993-08-17 | Allergan, Inc. | Method for producing amino-2-imidazoline derivatives |
IE911994A1 (en) * | 1990-07-03 | 1992-01-15 | Akzo Nv | 5-isothiazolamine derivatives |
WO1994008040A1 (en) * | 1992-09-25 | 1994-04-14 | Synaptic Pharmaceutical Corporation | Dna encoding human alpha 1 adrenergic receptors and uses thereof |
US5237032A (en) * | 1992-09-30 | 1993-08-17 | Istituto Guido Donegani S.P.A. | Microwave processing of carbonate monomers |
EP0599697A1 (fr) * | 1992-11-24 | 1994-06-01 | Synthelabo | Dérivés de pyrrole, leur préparation et leur application en thérapeutique |
US5447916A (en) * | 1993-07-30 | 1995-09-05 | Chiron Corporation | Peptoid alpha-1 adrenergic receptor ligands |
CA2181909C (en) | 1994-01-24 | 2008-10-07 | Stephen A. Munk | Aromatic 2-amino-imidazole derivatives as alpha-2a adrenoceptor agonists |
FR2719844B1 (fr) * | 1994-05-10 | 1996-06-07 | Synthelabo | Dérivés de 5,6-dihydro-4h-thiéno[3,4-c]pyrrole, leur préparation et leur application en thérapeutique. |
DE19514579A1 (de) * | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz |
US5866579A (en) * | 1997-04-11 | 1999-02-02 | Synaptic Pharmaceutical Corporation | Imidazole and imidazoline derivatives and uses thereof |
US6602897B2 (en) * | 2000-10-14 | 2003-08-05 | Boehringer Ingelheim Pharma Kg | m-Amino-phenylimino-imidazolidine derivatives for treating urinary incontinence |
-
1995
- 1995-04-20 DE DE19514579A patent/DE19514579A1/de not_active Withdrawn
-
1996
- 1996-04-13 CZ CZ973271A patent/CZ327197A3/cs unknown
- 1996-04-13 EP EP02025309A patent/EP1285653A1/de not_active Withdrawn
- 1996-04-13 CA CA2214338A patent/CA2214338C/en not_active Expired - Fee Related
- 1996-04-13 NZ NZ307509A patent/NZ307509A/xx unknown
- 1996-04-13 BR BR9608049A patent/BR9608049A/pt not_active Application Discontinuation
- 1996-04-13 HU HU9801599A patent/HUP9801599A3/hu unknown
- 1996-04-13 TR TR97/01212T patent/TR199701212T1/xx unknown
- 1996-04-13 WO PCT/EP1996/001568 patent/WO1996032939A1/de active IP Right Grant
- 1996-04-13 JP JP53145596A patent/JP3379960B2/ja not_active Expired - Fee Related
- 1996-04-13 KR KR1019970707509A patent/KR19990007985A/ko active IP Right Grant
- 1996-04-13 ES ES96914912T patent/ES2279521T3/es not_active Expired - Lifetime
- 1996-04-13 UA UA97115588A patent/UA62913C2/uk unknown
- 1996-04-13 SK SK1380-97A patent/SK138097A3/sk unknown
- 1996-04-13 EE EE9700267A patent/EE04416B1/xx not_active IP Right Cessation
- 1996-04-13 RU RU97119064/15A patent/RU2230061C2/ru not_active IP Right Cessation
- 1996-04-13 MX MX9707570A patent/MX9707570A/es not_active IP Right Cessation
- 1996-04-13 CN CN96193093A patent/CN1119148C/zh not_active Expired - Fee Related
- 1996-04-13 PL PL96324041A patent/PL184881B1/pl not_active IP Right Cessation
- 1996-04-13 DE DE59611411T patent/DE59611411D1/de not_active Expired - Lifetime
- 1996-04-13 EP EP96914912A patent/EP0821585B1/de not_active Expired - Lifetime
- 1996-04-13 AU AU56878/96A patent/AU719710B2/en not_active Ceased
- 1996-04-14 UY UY24206A patent/UY24206A1/es not_active IP Right Cessation
- 1996-04-18 IL IL11795696A patent/IL117956A/en not_active IP Right Cessation
- 1996-04-18 TW TW085104648A patent/TW403739B/zh not_active IP Right Cessation
- 1996-04-19 HR HR19514579.8A patent/HRP960187A2/hr not_active Application Discontinuation
- 1996-04-19 PE PE1996000273A patent/PE44297A1/es not_active Application Discontinuation
- 1996-04-19 ZA ZA963131A patent/ZA963131B/xx unknown
- 1996-04-19 YU YU24496A patent/YU24496A/sh unknown
- 1996-04-22 AR ARP960102266A patent/AR002043A1/es unknown
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1997
- 1997-10-15 BG BG101966A patent/BG64116B1/bg unknown
- 1997-10-17 NO NO974821A patent/NO974821L/no not_active Application Discontinuation
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1999
- 1999-01-11 US US09/227,944 patent/US6268389B1/en not_active Expired - Lifetime
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2000
- 2000-03-28 US US09/536,728 patent/US20020040150A1/en not_active Abandoned
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2002
- 2002-08-14 JP JP2002236562A patent/JP4141763B2/ja not_active Expired - Fee Related
- 2002-11-15 US US10/295,460 patent/US6858594B2/en not_active Expired - Lifetime
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2003
- 2003-02-07 RU RU2003104267/15A patent/RU2003104267A/ru not_active Application Discontinuation
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2004
- 2004-04-19 US US10/827,408 patent/US7019021B2/en not_active Expired - Fee Related
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