EE9700267A - a1L- agonistide kasutamine uriiniinkontinentsuse raviks - Google Patents

a1L- agonistide kasutamine uriiniinkontinentsuse raviks

Info

Publication number
EE9700267A
EE9700267A EE9700267A EE9700267A EE9700267A EE 9700267 A EE9700267 A EE 9700267A EE 9700267 A EE9700267 A EE 9700267A EE 9700267 A EE9700267 A EE 9700267A EE 9700267 A EE9700267 A EE 9700267A
Authority
EE
Estonia
Prior art keywords
agonists
treatment
urinary incontinence
incontinence
urinary
Prior art date
Application number
EE9700267A
Other languages
English (en)
Other versions
EE04416B1 (et
Inventor
Esser Franz
Staehle Helmut
Luettke Sven
Muramatsu Ikunobu
Kitagawa Hisato
M. D. Uchida Shuji
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of EE9700267A publication Critical patent/EE9700267A/et
Publication of EE04416B1 publication Critical patent/EE04416B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EE9700267A 1995-04-20 1996-04-13 a1L- agonistide kasutamine uriiniinkontinentsuse raviks EE04416B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19514579A DE19514579A1 (de) 1995-04-20 1995-04-20 Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
PCT/EP1996/001568 WO1996032939A1 (de) 1995-04-20 1996-04-13 VERWENDUNG VON α1L-AGONISTEN ZUR BEHANDLUNG DER HARNINKONTINENZ

Publications (2)

Publication Number Publication Date
EE9700267A true EE9700267A (et) 1998-06-15
EE04416B1 EE04416B1 (et) 2005-02-15

Family

ID=7759982

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700267A EE04416B1 (et) 1995-04-20 1996-04-13 a1L- agonistide kasutamine uriiniinkontinentsuse raviks

Country Status (31)

Country Link
US (4) US6268389B1 (et)
EP (2) EP0821585B1 (et)
JP (2) JP3379960B2 (et)
KR (1) KR19990007985A (et)
CN (1) CN1119148C (et)
AR (1) AR002043A1 (et)
AU (1) AU719710B2 (et)
BG (1) BG64116B1 (et)
BR (1) BR9608049A (et)
CA (1) CA2214338C (et)
CZ (1) CZ327197A3 (et)
DE (2) DE19514579A1 (et)
EE (1) EE04416B1 (et)
ES (1) ES2279521T3 (et)
HR (1) HRP960187A2 (et)
HU (1) HUP9801599A3 (et)
IL (1) IL117956A (et)
MX (1) MX9707570A (et)
NO (1) NO974821L (et)
NZ (1) NZ307509A (et)
PE (1) PE44297A1 (et)
PL (1) PL184881B1 (et)
RU (2) RU2230061C2 (et)
SK (1) SK138097A3 (et)
TR (1) TR199701212T1 (et)
TW (1) TW403739B (et)
UA (1) UA62913C2 (et)
UY (1) UY24206A1 (et)
WO (1) WO1996032939A1 (et)
YU (1) YU24496A (et)
ZA (1) ZA963131B (et)

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DE19514579A1 (de) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
US6503935B1 (en) 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
GB9906192D0 (en) 1999-03-18 1999-05-12 Medical Res Council Photoreleasable compounds
US6323231B1 (en) 2000-02-17 2001-11-27 Abbott Laboratories Use of α1A adrenoceptor agonists with α1B and α1D antagonism for the treatment of stress urinary incontinence
EP1328517A2 (de) * 2000-10-14 2003-07-23 Boehringer Ingelheim Pharma KG Neue m-amino-phenylimino-imidazolidin-derivate zur behandlung der harninkontinenz
US6602897B2 (en) 2000-10-14 2003-08-05 Boehringer Ingelheim Pharma Kg m-Amino-phenylimino-imidazolidine derivatives for treating urinary incontinence
GB0030580D0 (en) * 2000-12-15 2001-01-31 Medicare Man Consultancy Ltd Composition and method
DE10104369A1 (de) * 2001-02-01 2002-08-08 Boehringer Ingelheim Pharma Verwendung von 2-Amino-(4-hydroxy-2-methansulfonamidophenyl)ethanol zur Behandlung der Harninkontinenz
US6660772B2 (en) 2001-02-01 2003-12-09 Boehringer Ingelheim Pharma Kg Use of 2-amino-1-(4-hydroxy-2-methanesulfonamidophenyl)ethanol for treating urinary incontinence
US20020169193A1 (en) * 2001-02-10 2002-11-14 Pascale Pouzet Alkylphenyliminoimidazolidine derivatives for treating urinary incontinence
DE10106214A1 (de) * 2001-02-10 2002-08-14 Boehringer Ingelheim Pharma Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz
GB0114008D0 (en) * 2001-06-08 2001-08-01 Perry Robert E New therapautic use
US20040220240A1 (en) * 2001-11-28 2004-11-04 Pellegrini Cara A. Method of increasing the extent of absorption of tizanidine
US6455557B1 (en) 2001-11-28 2002-09-24 Elan Pharmaceuticals, Inc. Method of reducing somnolence in patients treated with tizanidine
EP1333028A1 (en) * 2002-01-31 2003-08-06 Boehringer Ingelheim Pharma GmbH & Co.KG 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
US6703409B2 (en) 2002-01-31 2004-03-09 Boehringer Ingelheim Pharma Gmbh & Co Kg 2′-Halo-3′,5′-dialkoxyphen-1′-yl-imino-2-imidazolidine and the use thereof as a drug
BR0307406A (pt) * 2002-02-01 2004-12-28 Hoffmann La Roche Indóis substituìdos como agonistas alfa-1
DE10352132A1 (de) * 2003-11-04 2005-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Zusammensetzung aus einem Beta-3-Adrenozeptor-Agonisten und einem Alpha Agonisten
RU2473545C2 (ru) * 2007-02-02 2013-01-27 Ф.Хоффманн-Ля Рош Аг Новые 2-аминооксазолины в качестве лигандов taar1 для заболеваний цнс
MX2009008465A (es) * 2007-02-15 2009-08-20 Hoffmann La Roche Nuevas 2-aminooxazolinas como ligandos de taar1.
BRPI0815038A2 (pt) * 2007-08-02 2015-03-17 Hoffmann La Roche Uso de derivados de benzamida para o tratamento de transtornos do cns
EP2188261A1 (en) * 2007-08-15 2010-05-26 Allergan, Inc. Therapeutic compounds
CA2696315A1 (en) * 2007-08-15 2009-02-19 Allergan, Inc. Heterocyclyl substituted fused carbocyles useful in the treatment of conditions such as glaucoma and pain
JP4168086B1 (ja) * 2008-04-16 2008-10-22 国立大学法人福井大学 イミダゾリン誘導体
US8242153B2 (en) * 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
CA2728480A1 (en) * 2008-07-24 2010-01-28 F. Hoffmann-La Roche Ag 4,5-dihydro-oxazol-2-yl derivatives
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US20100311798A1 (en) * 2009-06-05 2010-12-09 Decoret Guillaume 2-aminooxazolines as taar1 ligands
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JPWO2015152196A1 (ja) * 2014-03-31 2017-04-13 東レ株式会社 イミダゾリン誘導体及びその医薬用途
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Also Published As

Publication number Publication date
HRP960187A2 (en) 1997-12-31
HUP9801599A3 (en) 1999-04-28
US20030114425A1 (en) 2003-06-19
HUP9801599A2 (hu) 1999-01-28
EP1285653A1 (de) 2003-02-26
DE59611411D1 (de) 2007-02-22
ES2279521T3 (es) 2007-08-16
IL117956A0 (en) 1996-08-04
CN1119148C (zh) 2003-08-27
NO974821D0 (no) 1997-10-17
WO1996032939A1 (de) 1996-10-24
PE44297A1 (es) 1997-10-27
US6858594B2 (en) 2005-02-22
UA62913C2 (en) 2004-01-15
PL324041A1 (en) 1998-05-11
PL184881B1 (pl) 2003-01-31
US20040198796A1 (en) 2004-10-07
RU2003104267A (ru) 2004-08-27
AU5687896A (en) 1996-11-07
AU719710B2 (en) 2000-05-18
MX9707570A (es) 1997-12-31
US7019021B2 (en) 2006-03-28
JPH11503738A (ja) 1999-03-30
CA2214338A1 (en) 1996-10-24
IL117956A (en) 2001-11-25
US6268389B1 (en) 2001-07-31
EE04416B1 (et) 2005-02-15
JP2003064058A (ja) 2003-03-05
RU2230061C2 (ru) 2004-06-10
CZ327197A3 (cs) 1998-05-13
NZ307509A (en) 2000-06-23
DE19514579A1 (de) 1996-10-24
UY24206A1 (es) 2000-08-21
NO974821L (no) 1997-10-17
ZA963131B (en) 1996-10-21
KR19990007985A (ko) 1999-01-25
EP0821585A1 (de) 1998-02-04
SK138097A3 (en) 1998-02-04
AR002043A1 (es) 1998-01-07
JP4141763B2 (ja) 2008-08-27
US20020040150A1 (en) 2002-04-04
BR9608049A (pt) 1999-01-26
TW403739B (en) 2000-09-01
YU24496A (sh) 1998-12-23
EP0821585B1 (de) 2007-01-10
BG101966A (en) 1998-09-30
TR199701212T1 (xx) 1998-03-21
CN1180311A (zh) 1998-04-29
JP3379960B2 (ja) 2003-02-24
CA2214338C (en) 2010-10-19
BG64116B1 (bg) 2004-01-30

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