MTP837B - Derivatives 2 finino-imidazolidire - Google Patents

Derivatives 2 finino-imidazolidire

Info

Publication number
MTP837B
MTP837B MT837A MTP837A MTP837B MT P837 B MTP837 B MT P837B MT 837 A MT837 A MT 837A MT P837 A MTP837 A MT P837A MT P837 B MTP837 B MT P837B
Authority
MT
Malta
Prior art keywords
imidazolidire
finino
derivatives
Prior art date
Application number
MT837A
Inventor
Henri Ramuz
Original Assignee
Hoffman La Roche And Co Aktien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffman La Roche And Co Aktien filed Critical Hoffman La Roche And Co Aktien
Publication of MTP837B publication Critical patent/MTP837B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
MT837A 1977-11-07 1978-10-26 Derivatives 2 finino-imidazolidire MTP837B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU78467 1977-11-07
CH966878 1978-09-15

Publications (1)

Publication Number Publication Date
MTP837B true MTP837B (en) 1979-10-22

Family

ID=25705131

Family Applications (1)

Application Number Title Priority Date Filing Date
MT837A MTP837B (en) 1977-11-07 1978-10-26 Derivatives 2 finino-imidazolidire

Country Status (30)

Country Link
US (3) US4244957A (en)
EP (1) EP0002010B1 (en)
JP (1) JPS5473779A (en)
AR (1) AR223656A1 (en)
AT (1) AT371112B (en)
AU (1) AU4132478A (en)
BR (1) BR7807317A (en)
CA (1) CA1106847A (en)
CS (1) CS212309B2 (en)
DD (1) DD139847A5 (en)
DE (2) DE2861952D1 (en)
DK (1) DK494978A (en)
EG (1) EG13665A (en)
ES (3) ES480112A1 (en)
FI (1) FI783393A7 (en)
FR (1) FR2407919A1 (en)
GB (2) GB2086379B (en)
IL (1) IL55832A0 (en)
IT (1) IT1160046B (en)
MC (1) MC1223A1 (en)
MT (1) MTP837B (en)
NL (1) NL7811070A (en)
NO (1) NO783719L (en)
NZ (1) NZ188798A (en)
OA (1) OA06084A (en)
PL (1) PL210759A1 (en)
PT (1) PT68752A (en)
RO (1) RO76151A (en)
SE (1) SE7811455L (en)
SU (2) SU831073A3 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287201A (en) * 1980-03-03 1981-09-01 Merck & Co., Inc. Anovulatory method and chicken feed compositions
CA1175434A (en) * 1980-09-10 1984-10-02 Hoffmann-La Roche Limited ¬(2-phenylamino-1-imidazolidinyloxy)methyl| pyridine 1-oxide derivatives
DE3642453A1 (en) * 1986-12-12 1988-06-23 Bayer Ag NEW 5-TRIHALOGENMETHYL ISOXAZOLES CONTAINING FLUOR AND A METHOD FOR THE PRODUCTION THEREOF
WO1995029165A2 (en) * 1994-04-26 1995-11-02 Syntex (U.S.A.) Inc. Benzocycloalkylaz0lethione derivatives as dopamin beta-hydroxylase inhibitors
DE19514579A1 (en) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Use of alpha-1-olone agonists for the treatment of urinary incontinence
WO2002004421A2 (en) * 2000-07-07 2002-01-17 Medicure International Inc. Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
GB2374251A (en) * 2001-04-04 2002-10-09 Secr Defence Base station transmitter
US20030139606A1 (en) * 2001-11-09 2003-07-24 Ray Anup Kumar Process for preparing 5-methylisoxazole-4-carboxylic- (4'-trifluoromethyl)-anilide
US6703409B2 (en) 2002-01-31 2004-03-09 Boehringer Ingelheim Pharma Gmbh & Co Kg 2′-Halo-3′,5′-dialkoxyphen-1′-yl-imino-2-imidazolidine and the use thereof as a drug
EP1333028A1 (en) * 2002-01-31 2003-08-06 Boehringer Ingelheim Pharma GmbH & Co.KG 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
US8653131B2 (en) * 2008-08-22 2014-02-18 Baxter Healthcare S.A. Polymeric benzyl carbonate-derivatives

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670274U (en) 1953-07-30 1954-01-14 Leo Schirk SHEET STEEL SWITCHBOARD.
DE1815788U (en) 1959-12-12 1960-07-28 Walther Loeffler VALVE FOR SINKS, WASHBASINS, BIDETS, TUBS.
US3236857A (en) 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
NL123037C (en) 1963-10-04
DE1545628A1 (en) 1965-10-01 1970-06-25 Boehringer Sohn Ingelheim Process for the preparation of antihypertensive and sedative derivatives of 2- (2-haloanilino) -1,3-diazacyclopentene- (2)
DE1670274A1 (en) * 1966-10-31 1970-07-16 Boehringer Sohn Ingelheim New process for the preparation of 2-arylamino-1,3-diazacycloalkenene (2)
ES352379A1 (en) 1967-05-26 1969-08-01 Boehringer Sohn Ingelheim Procedure for the preparation of 1,3-diazaciclopenten (2) replaced in position 2. (Machine-translation by Google Translate, not legally binding)
DE1670230A1 (en) 1967-05-26 1971-01-21 Boehringer Sohn Ingelheim New process for the preparation of 1,3-diazacycloalkenes substituted in the 2-position (2)
US3454301A (en) * 1967-09-29 1969-07-08 John W Lehmann Glare-inhibiting device
GB1246312A (en) * 1968-01-10 1971-09-15 Syntex Energy Res Inc 4,5-substituted n-oxy and hydroxy hydroimidazoles
DE1770872A1 (en) 1968-08-26 1972-01-13 Dresden Arzneimittel Process for the preparation of imidazoline-2 derivatives
BE721781A (en) 1968-10-03 1969-04-03
BE759048A (en) * 1969-11-17 1971-05-17 Boehringer Sohn Ingelheim NEW N-AMINOALCOYL-ARYLAMINO-IMIDAZOLINES- (2) SUBSTITUTES AND METHODS FOR MAKING THEM
DE2016290A1 (en) * 1970-04-06 1971-11-04 C H Boehrmger Sohn, 6507 Ingel heim Substituted N hydroxylakyl 2 arylamine) imidazolines (2) and process for their preparation
US3740412A (en) * 1970-04-08 1973-06-19 Synvar Ass Imidazoline-3-oxide-1-oxyl derivatives
DE2038107A1 (en) * 1970-07-31 1972-02-10 Henkel & Cie Gmbh Liquid stabilized enzyme preparations which can optionally be used as washing or cleaning agents
US3799942A (en) * 1971-04-12 1974-03-26 Syva Corp 4,5-substituted n-oxy and hydroxy hydroimidazoles
BE787477A (en) * 1971-08-12 1973-02-12 Bayer Ag 1-PHENYL-2-IMINO-IMIDAZOLIDINES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS REPELLENTS AGAINST BIRDS
DE2457979A1 (en) 1974-12-07 1976-06-16 Beiersdorf Ag N-(Aryl hydroxyamino)-imidazoline-2 antihypertensives - prepd. from corresp. N-arylamino cpd. by peracid oxidn. then opt. alkylation
DE2523103C3 (en) * 1975-05-24 1979-11-29 C.H. Boehringer Sohn, 6507 Ingelheim Substituted 2- [N-Progargyl-N- (2-chlorophenyl) amino] -imidazoline- ^), their acid addition salts, processes for their preparation and their use
AT339897B (en) * 1975-09-25 1977-11-10 Chemie Linz Ag PROCESS FOR PREPARING THE NEW 1-BENZOYL-2- (2 ', 6'-DICHLOROPHENYLAMINO) -2-IMIDAZOLINE AND THE SALT THEREOF
DE2626128A1 (en) * 1976-06-11 1977-12-22 Beiersdorf Ag (1)-Imidazolinyl-benzimidazolinones - and intermediate imidazolinyl-phenylene-diamines, useful as hypotensives
DE2709720A1 (en) * 1977-03-05 1978-09-07 Beiersdorf Ag Hypotensive 1-oxy-2-arylamino-2-imidazoline derivs. - prepd. by reacting N-oxy-ethylene:di:amine cpds. with N-phenyl-isocyanide di:chloride cpds.
US4131679A (en) * 1977-07-26 1978-12-26 Sandoz, Inc. Substituted 4-hydroxy pyridones
DE2811847A1 (en) * 1978-03-17 1979-09-20 Lentia Gmbh NEW ARYLAMINOIMIDAZOLINE DERIVATIVES, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS

Also Published As

Publication number Publication date
SE7811455L (en) 1979-07-02
AR223656A1 (en) 1981-09-15
MC1223A1 (en) 1979-07-20
NO783719L (en) 1979-05-08
GB2086379A (en) 1982-05-12
JPS5473779A (en) 1979-06-13
ES480113A1 (en) 1980-04-01
PT68752A (en) 1978-12-01
EP0002010B1 (en) 1982-07-14
GB2008579A (en) 1979-06-06
ES480112A1 (en) 1980-04-01
GB2008579B (en) 1982-11-03
IL55832A0 (en) 1978-12-17
SU831073A3 (en) 1981-05-15
BR7807317A (en) 1979-07-24
FI783393A7 (en) 1979-05-08
NZ188798A (en) 1981-04-24
DE2861952D1 (en) 1982-09-02
EP0002010A1 (en) 1979-05-30
CS212309B2 (en) 1982-03-26
DK494978A (en) 1979-05-08
AU4132478A (en) 1979-05-17
PL210759A1 (en) 1980-03-10
DD139847A5 (en) 1980-01-23
DE2847766A1 (en) 1979-05-10
IT1160046B (en) 1987-03-04
US4355033A (en) 1982-10-19
CA1106847A (en) 1981-08-11
AT371112B (en) 1983-06-10
ATA791378A (en) 1982-10-15
EG13665A (en) 1982-03-31
NL7811070A (en) 1979-05-09
RO76151A (en) 1981-08-30
GB2086379B (en) 1982-11-10
ES480111A1 (en) 1980-04-01
SU910119A3 (en) 1982-02-28
US4244957A (en) 1981-01-13
FR2407919A1 (en) 1979-06-01
OA06084A (en) 1981-06-30
US4511720A (en) 1985-04-16
IT7829486A0 (en) 1978-11-06

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