EE03608B1 - Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid - Google Patents

Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Info

Publication number
EE03608B1
EE03608B1 EE9700315A EE9700315A EE03608B1 EE 03608 B1 EE03608 B1 EE 03608B1 EE 9700315 A EE9700315 A EE 9700315A EE 9700315 A EE9700315 A EE 9700315A EE 03608 B1 EE03608 B1 EE 03608B1
Authority
EE
Estonia
Prior art keywords
taxoids
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
EE9700315A
Other languages
English (en)
Other versions
EE9700315A (et
Inventor
Bouchard Herv
Bourzat Jean-Dominique
Commer�on Alain
Original Assignee
Rh�Ne-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9503545A external-priority patent/FR2732340B1/fr
Priority claimed from FR9515381A external-priority patent/FR2742754B1/fr
Application filed by Rh�Ne-Poulenc Rorer S.A. filed Critical Rh�Ne-Poulenc Rorer S.A.
Publication of EE9700315A publication Critical patent/EE9700315A/et
Publication of EE03608B1 publication Critical patent/EE03608B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EE9700315A 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid EE03608B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9503545A FR2732340B1 (fr) 1995-03-27 1995-03-27 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR9515381A FR2742754B1 (fr) 1995-12-22 1995-12-22 Procede de preparation de taxoides
PCT/FR1996/000440 WO1996030355A1 (fr) 1995-03-27 1996-03-25 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
EE9700315A EE9700315A (et) 1998-06-15
EE03608B1 true EE03608B1 (et) 2002-02-15

Family

ID=26231838

Family Applications (2)

Application Number Title Priority Date Filing Date
EE9700315A EE03608B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid
EE9700323A EE03609B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Family Applications After (1)

Application Number Title Priority Date Filing Date
EE9700323A EE03609B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Country Status (41)

Country Link
US (3) US5889043A (et)
EP (2) EP0817780B1 (et)
JP (2) JP3790826B2 (et)
KR (2) KR100485309B1 (et)
CN (2) CN1213042C (et)
AP (2) AP785A (et)
AR (1) AR001440A1 (et)
AT (2) ATE188471T1 (et)
AU (2) AU703278B2 (et)
BG (2) BG63121B1 (et)
BR (2) BR9607929A (et)
CA (2) CA2214321C (et)
CO (1) CO4700576A1 (et)
CZ (2) CZ287326B6 (et)
DE (2) DE69604653T2 (et)
DK (2) DK0817780T3 (et)
DZ (1) DZ2009A1 (et)
EA (2) EA000567B1 (et)
EE (2) EE03608B1 (et)
ES (2) ES2140075T3 (et)
GE (2) GEP20002188B (et)
GR (2) GR3031526T3 (et)
HU (2) HU223666B1 (et)
IL (1) IL117636A (et)
IS (2) IS2058B (et)
MA (1) MA23823A1 (et)
MY (1) MY121225A (et)
NO (2) NO316607B1 (et)
NZ (2) NZ304900A (et)
OA (2) OA10513A (et)
PE (1) PE51097A1 (et)
PL (2) PL188284B1 (et)
PT (1) PT817779E (et)
RO (2) RO115878B1 (et)
SK (2) SK281927B6 (et)
TN (1) TNSN96043A1 (et)
TR (2) TR199701042T1 (et)
TW (1) TW394765B (et)
UY (2) UY24192A1 (et)
WO (2) WO1996030355A1 (et)
ZA (1) ZA962399B (et)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
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US6500858B2 (en) 1994-10-28 2002-12-31 The Research Foundation Of The State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US5811452A (en) * 1997-01-08 1998-09-22 The Research Foundation Of State University Of New York Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
FR2771092B1 (fr) * 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides
US6346543B1 (en) * 1998-08-17 2002-02-12 Aventis Pharma S.A. Use of a taxoid to treat abnormal cell proliferation in the brain
EP0982027A1 (en) * 1998-08-17 2000-03-01 Aventis Pharma S.A. Taxoid derivatives for treating abnormal cell proliferation of the brain
WO2000010547A2 (en) * 1998-08-20 2000-03-02 Aventis Pharma S.A. New use of taxoid derivatives
EP0982028A1 (en) * 1998-08-20 2000-03-01 Aventis Pharma S.A. New use of taxoid derivatives
EP1020188A1 (en) * 1999-01-13 2000-07-19 Aventis Pharma S.A. New use of taxoid derivatives
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CN1362876A (zh) * 2000-02-02 2002-08-07 佛罗里达州立大学研究基金有限公司 C10杂取代的乙酸基紫衫烷抗肿瘤剂
WO2002024178A2 (en) * 2000-09-22 2002-03-28 Bristol-Myers Squibb Company Method for reducing toxicity of combined chemotherapies
PL366100A1 (en) * 2000-09-22 2005-01-24 Bristol-Myers Squibb Company Method for reducing toxicity of combined chemotherapies
US6593334B1 (en) 2002-05-02 2003-07-15 The University Of North Carolina At Chapel Hill Camptothecin-taxoid conjugates as antimitotic and antitumor agents
KR101268258B1 (ko) 2002-09-06 2013-05-31 인설트 테라페틱스, 인코퍼레이티드 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체
WO2004043390A2 (en) * 2002-11-08 2004-05-27 Bristol-Myers Squibb Company Pharmaceutical compositions and methods of using taxane derivatives
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US7064980B2 (en) * 2003-09-17 2006-06-20 Sandisk Corporation Non-volatile memory and method with bit line coupled compensation
FR2859996B1 (fr) 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
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PE20050693A1 (es) 2004-02-13 2005-09-27 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
JP2008530122A (ja) * 2005-02-14 2008-08-07 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ１０シクロプロピルエステル置換タキサン組成物
EP2428510A3 (en) 2005-03-31 2012-06-13 Accord Healthcare Inc. Preparation of taxanes from 9-dihydro-13-acetylbaccatin III
DK1948669T3 (da) * 2005-11-04 2013-10-07 Accord Healthcare Inc Nye fremgangsmåder til fremstiling af taxaner under anvendelse af chirale hjælpestoffer
US7847111B2 (en) * 2006-06-19 2010-12-07 Canada Inc. Semi-synthetic route for the preparation of paclitaxel, docetaxel, and 10-deacetylbaccatin III from 9-dihydro-13-acetylbaccatin III
WO2008067403A2 (en) * 2006-11-28 2008-06-05 Encore Health Llc Presbyopia treatment by lens alteration
JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス， インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
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FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
WO2009145981A1 (en) * 2008-03-31 2009-12-03 Florida State University Research Foundation, Inc. C(10) ethyl ester and c(10) cyclopropyl ester substituted taxanes
CA2732508C (en) 2008-08-11 2016-03-15 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
FR2945211A1 (fr) 2009-05-06 2010-11-12 Sanofi Aventis Combinaison antitumorale comprenant la cabazitaxel et la capecitabine
CA2779009A1 (en) 2009-10-29 2011-05-05 Aventis Pharma S.A. Novel antitumoral use of cabazitaxel
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US8791279B2 (en) * 2010-12-13 2014-07-29 Yung Shin Pharm. Ind. Co., Ltd. Process for preparing taxoids from baccatin derivatives using lewis acid catalyst
US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
US20130331443A1 (en) 2010-12-22 2013-12-12 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
US20130338216A1 (en) 2010-12-22 2013-12-19 Nektar Therapeutics Deuterated and/or fluorinated taxane derivatives
CN102060815B (zh) * 2010-12-24 2012-09-26 重庆泰濠制药有限公司 一种紫杉烷类化合物的制备方法
PL2678011T3 (pl) 2011-02-25 2019-12-31 Aventis Pharma S.A. Kombinacja przeciwnowotworowa zawierająca kabazytaksel i cisplatynę
EP2620148A1 (en) 2012-01-27 2013-07-31 Aventis Pharma S.A. Antitumoral combination comprising cabazitaxel and cisplatin
EP2491925A1 (en) 2011-02-25 2012-08-29 Aventis Pharma S.A. Antitumoral combination comprising cabazitaxel and cisplatin
EA023950B1 (ru) * 2011-04-12 2016-07-29 Тева Фармасьютикалз Интернэшнл Гмбх Твердофазные формы кабазитаксела и способы их получения
MX2014001221A (es) 2011-08-02 2014-03-27 Astellas Pharma Inc Metodo para tratar el cancer mediante el uso combinado de farmacos.
TWI526437B (zh) 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
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CN102336726B (zh) * 2011-09-30 2014-11-26 重庆泰濠制药有限公司 一种卡巴他赛的制备方法
US20130090484A1 (en) * 2011-10-11 2013-04-11 Scinopharm Taiwan Ltd. Process for making an intermediate of cabazitaxel
CN102408397B (zh) 2011-10-19 2014-08-20 上海贝美医药科技有限公司 紫杉烷类衍生物及其制备方法
CN102424672A (zh) * 2011-10-20 2012-04-25 江苏红豆杉生物科技有限公司 脱保护基制备二甲氧基紫杉烷类化合物的方法
CN102516281B (zh) * 2011-10-20 2015-02-04 江苏红豆杉生物科技股份有限公司 一种10-脱乙酰基巴卡丁iii及其衍生物甲氧基化的方法
CN102603724B (zh) * 2011-10-20 2014-02-26 江苏红豆杉生物科技股份有限公司 二甲氧基紫杉烷类化合物纯化精制的方法
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CN104650012A (zh) * 2013-11-22 2015-05-27 天士力控股集团有限公司 一种紫杉烷类化合物
CN104086514A (zh) * 2014-06-19 2014-10-08 上海应用技术学院 紫杉醇衍生物及其制备方法
PL3258931T3 (pl) 2015-02-17 2020-12-28 Erasmus University Medical Center Rotterdam Zastosowanie kabazitakselu w leczeniu nowotworu złośliwego prostaty
EP3093014A1 (en) 2015-05-13 2016-11-16 Aventis Pharma S.A. Cabazitaxel and its use for treating cancer
WO2020249507A1 (en) 2019-06-11 2020-12-17 Indena S.P.A. Anhydrous crystalline form of cabazitaxel, a process for its preparation and pharmaceutical compositions containing it
KR20220047589A (ko) 2019-08-08 2022-04-18 래크나 리미티드 암 치료 방법
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MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
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FR2771092B1 (fr) 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides

Also Published As

Publication number Publication date
ZA962399B (en) 1996-10-01
JPH11500141A (ja) 1999-01-06
SK130297A3 (en) 1998-03-04
US6331635B1 (en) 2001-12-18
HUP9801201A3 (en) 2000-12-28
CN1179775A (zh) 1998-04-22
ATE185562T1 (de) 1999-10-15
PL188284B1 (pl) 2005-01-31
NO973922L (no) 1997-08-26
WO1996030355A1 (fr) 1996-10-03
BR9607929A (pt) 1998-06-02
DE69604653T2 (de) 2000-05-31
PT817779E (pt) 2000-04-28
CZ303297A3 (cs) 1998-01-14
GEP20002211B (en) 2000-08-25
CZ287468B6 (en) 2000-12-13
DZ2009A1 (fr) 2002-10-23
IL117636A (en) 2004-08-31
RO115878B1 (ro) 2000-07-28
CA2214321A1 (fr) 1996-10-03
AP9701090A0 (en) 1997-10-31
AP753A (en) 1999-07-21
OA10514A (fr) 2002-04-22
EP0817780A1 (fr) 1998-01-14
EE03609B1 (et) 2002-02-15
EE9700323A (et) 1998-06-15
AR001440A1 (es) 1997-10-22
EE9700315A (et) 1998-06-15
IS2058B (is) 2005-10-14
ES2140075T3 (es) 2000-02-16
HU223666B1 (hu) 2004-11-29
SK281928B6 (sk) 2001-09-11
NO973923L (no) 1997-08-26
AU711227B2 (en) 1999-10-07
ATE188471T1 (de) 2000-01-15
WO1996030356A1 (fr) 1996-10-03
SK281927B6 (sk) 2001-09-11
HUP9801204A3 (en) 2000-12-28
EA199700269A1 (ru) 1998-04-30
NO973922D0 (no) 1997-08-26
IS2056B (is) 2005-10-14
BG101918A (en) 1998-10-30
HUP9801204A1 (hu) 2000-05-28
KR100485309B1 (ko) 2005-10-12
US20020038038A1 (en) 2002-03-28
RO115877B1 (ro) 2000-07-28
NO973923D0 (no) 1997-08-26
BG101917A (en) 1998-10-30
IL117636A0 (en) 1996-07-23
CN1152870C (zh) 2004-06-09
TW394765B (en) 2000-06-21
NO316379B1 (no) 2004-01-19
JP2941951B2 (ja) 1999-08-30
DE69604653D1 (de) 1999-11-18
JPH11502531A (ja) 1999-03-02
EA000567B1 (ru) 1999-12-29
DK0817780T3 (da) 2000-03-27
CA2214319C (fr) 2004-02-17
CA2214319A1 (fr) 1996-10-03
PE51097A1 (es) 1997-12-22
OA10513A (fr) 2002-04-22
PL322465A1 (en) 1998-02-02
KR100297196B1 (ko) 2001-11-22
JP3790826B2 (ja) 2006-06-28
MX9706278A (es) 1997-10-31
EA199700270A1 (ru) 1998-02-26
IS4567A (is) 1997-09-23
EP0817779B1 (fr) 2000-01-05
EP0817779A1 (fr) 1998-01-14
CN1213042C (zh) 2005-08-03
MA23823A1 (fr) 1996-10-01
DE69606028T2 (de) 2000-08-10
KR19980703287A (ko) 1998-10-15
HU223732B1 (hu) 2004-12-28
PL188987B1 (pl) 2005-05-31
HUP9801201A2 (hu) 2000-05-28
AP9701093A0 (en) 1997-10-31
UY24370A1 (es) 2001-10-25
AU5278096A (en) 1996-10-16
AU703278B2 (en) 1999-03-25
BG63121B1 (bg) 2001-04-30
CZ287326B6 (en) 2000-10-11
NO316607B1 (no) 2004-03-08
TR199701040T1 (xx) 1998-01-21
IS4536A (is) 1997-07-31
DK0817779T3 (da) 2000-06-19
CO4700576A1 (es) 1998-12-29
GEP20002188B (en) 2000-07-25
EA000709B1 (ru) 2000-02-28
UY24192A1 (es) 1996-06-14
BR9607930A (pt) 1998-06-02
NZ304900A (en) 1998-09-24
MY121225A (en) 2006-01-28
TNSN96043A1 (fr) 2005-03-15
MX9706568A (es) 1997-11-29
AU5278196A (en) 1996-10-16
KR19980703357A (ko) 1998-10-15
TR199701042T1 (xx) 1998-01-21
GR3031526T3 (en) 2000-01-31
SK130197A3 (en) 1998-04-08
EP0817780B1 (fr) 1999-10-13
DE69606028D1 (de) 2000-02-10
PL322499A1 (en) 1998-02-02
NZ304901A (en) 1998-12-23
ES2143187T3 (es) 2000-05-01
GR3032316T3 (en) 2000-04-27
US5889043A (en) 1999-03-30
CZ303097A3 (cs) 1998-01-14
BG63009B1 (bg) 2001-01-31
CN1179776A (zh) 1998-04-22
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US6387946B1 (en) 2002-05-14
AP785A (en) 1999-11-26

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