MX9706278A - Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
MX9706278A
MX9706278A MX9706278A MX9706278A MX9706278A MX 9706278 A MX9706278 A MX 9706278A MX 9706278 A MX9706278 A MX 9706278A MX 9706278 A MX9706278 A MX 9706278A MX 9706278 A MX9706278 A MX 9706278A
Authority
MX
Mexico
Prior art keywords
radical
general formula
optionally substitued
preparation
pharmaceutical compositions
Prior art date
Application number
MX9706278A
Other languages
English (en)
Other versions
MXPA97006278A (es
Inventor
Herve Bouchard
Jean-Dominique Bourzat
Alain Commercon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9503545A external-priority patent/FR2732340B1/fr
Priority claimed from FR9515381A external-priority patent/FR2742754B1/fr
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of MX9706278A publication Critical patent/MX9706278A/es
Publication of MXPA97006278A publication Critical patent/MXPA97006278A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se describen los nuevos taxoides de la formula general (I): su preparacion y las composiciones farmacéuticas que los contienen. En la formula general (I): Z representa un átomo de hidrogeno o un radical de la formula general (II): en la cual R1 representa un radical benzoilo eventualmente sustituido, o un radical tenoilo o furoilo, un radical R1-O-CO- en el cual R2 representa un radical alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquenilo, bicicloalquilo, fenilo eventualmente sustituido o heterociclo, R3 representa un radical alquilo, alquenilo, alquinilo, cicloalquilo, fenilo, naftilo o heterocíclico aromático, R4 representa un radical alcoxi, alqueniloxi, alquiniloxi eventualmente sustituido o un radical cicloalquiloxi o cicloalqueniloxi, y R5 representa un radical alcoxi, alqueniloxi, alquiniloxi eventualmente sustituido o un radical cicloalquiloxi o cicloalqueniloxi. Los nuevos productos de la formula general (I) en la cual Z representa un radical de la formula general (II), presentan propiedades antitumorales y antileucémicas notables.
MXPA/A/1997/006278A 1995-03-27 1997-08-18 Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen MXPA97006278A (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
FR9503545A FR2732340B1 (fr) 1995-03-27 1995-03-27 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR9503545 1995-03-27
FR9515381 1995-12-22
FR95/15381 1995-12-22
FR95/03545 1995-12-22
FR9515381A FR2742754B1 (fr) 1995-12-22 1995-12-22 Procede de preparation de taxoides
PCT/FR1996/000440 WO1996030355A1 (fr) 1995-03-27 1996-03-25 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
MX9706278A true MX9706278A (es) 1997-10-31
MXPA97006278A MXPA97006278A (es) 1998-07-03

Family

ID=

Also Published As

Publication number Publication date
DZ2009A1 (fr) 2002-10-23
MA23823A1 (fr) 1996-10-01
IS2058B (is) 2005-10-14
ZA962399B (en) 1996-10-01
EE9700315A (et) 1998-06-15
CZ287468B6 (en) 2000-12-13
AU5278196A (en) 1996-10-16
US20020038038A1 (en) 2002-03-28
BR9607929A (pt) 1998-06-02
OA10513A (fr) 2002-04-22
EE03608B1 (et) 2002-02-15
AU703278B2 (en) 1999-03-25
TW394765B (en) 2000-06-21
ES2140075T3 (es) 2000-02-16
KR100485309B1 (ko) 2005-10-12
NO973923L (no) 1997-08-26
HU223732B1 (hu) 2004-12-28
IS2056B (is) 2005-10-14
ES2143187T3 (es) 2000-05-01
EP0817779A1 (fr) 1998-01-14
US5889043A (en) 1999-03-30
BG101917A (en) 1998-10-30
WO1996030355A1 (fr) 1996-10-03
TNSN96043A1 (fr) 2005-03-15
EA199700269A1 (ru) 1998-04-30
AU5278096A (en) 1996-10-16
PE51097A1 (es) 1997-12-22
SK281928B6 (sk) 2001-09-11
CN1152870C (zh) 2004-06-09
GEP20002211B (en) 2000-08-25
HU223666B1 (hu) 2004-11-29
US6387946B1 (en) 2002-05-14
MX9706568A (es) 1997-11-29
DE69606028T2 (de) 2000-08-10
NZ304901A (en) 1998-12-23
PT817779E (pt) 2000-04-28
AP9701090A0 (en) 1997-10-31
NO973923D0 (no) 1997-08-26
AU711227B2 (en) 1999-10-07
AR001440A1 (es) 1997-10-22
NO973922L (no) 1997-08-26
IL117636A (en) 2004-08-31
AP9701093A0 (en) 1997-10-31
EE9700323A (et) 1998-06-15
CZ303297A3 (cs) 1998-01-14
JP3790826B2 (ja) 2006-06-28
RO115878B1 (ro) 2000-07-28
NO316607B1 (no) 2004-03-08
DK0817779T3 (da) 2000-06-19
KR19980703357A (ko) 1998-10-15
HUP9801201A3 (en) 2000-12-28
GR3032316T3 (en) 2000-04-27
IS4536A (is) 1997-07-31
CZ287326B6 (en) 2000-10-11
PL188987B1 (pl) 2005-05-31
KR19980703287A (ko) 1998-10-15
SK130297A3 (en) 1998-03-04
DE69604653D1 (de) 1999-11-18
UY24370A1 (es) 2001-10-25
SK281927B6 (sk) 2001-09-11
SK130197A3 (en) 1998-04-08
CN1179776A (zh) 1998-04-22
NO316379B1 (no) 2004-01-19
JP2941951B2 (ja) 1999-08-30
BG101918A (en) 1998-10-30
KR100297196B1 (ko) 2001-11-22
CA2214319C (fr) 2004-02-17
OA10514A (fr) 2002-04-22
ATE188471T1 (de) 2000-01-15
CZ303097A3 (cs) 1998-01-14
TR199701040T1 (xx) 1998-01-21
NZ304900A (en) 1998-09-24
TR199701042T1 (xx) 1998-01-21
DK0817780T3 (da) 2000-03-27
CN1213042C (zh) 2005-08-03
AP785A (en) 1999-11-26
IS4567A (is) 1997-09-23
EA199700270A1 (ru) 1998-02-26
CA2214319A1 (fr) 1996-10-03
PL188284B1 (pl) 2005-01-31
MY121225A (en) 2006-01-28
BG63009B1 (bg) 2001-01-31
EA000567B1 (ru) 1999-12-29
HUP9801204A1 (hu) 2000-05-28
EP0817780A1 (fr) 1998-01-14
RO115877B1 (ro) 2000-07-28
EA000709B1 (ru) 2000-02-28
US6331635B1 (en) 2001-12-18
HUP9801204A3 (en) 2000-12-28
DE69606028D1 (de) 2000-02-10
IL117636A0 (en) 1996-07-23
WO1996030356A1 (fr) 1996-10-03
EP0817779B1 (fr) 2000-01-05
BG63121B1 (bg) 2001-04-30
EP0817780B1 (fr) 1999-10-13
CA2214321A1 (fr) 1996-10-03
ATE185562T1 (de) 1999-10-15
JPH11500141A (ja) 1999-01-06
PL322499A1 (en) 1998-02-02
BR9607930A (pt) 1998-06-02
CN1179775A (zh) 1998-04-22
CO4700576A1 (es) 1998-12-29
GR3031526T3 (en) 2000-01-31
AP753A (en) 1999-07-21
CA2214321C (fr) 2008-01-22
PL322465A1 (en) 1998-02-02
UY24192A1 (es) 1996-06-14
EE03609B1 (et) 2002-02-15
DE69604653T2 (de) 2000-05-31
JPH11502531A (ja) 1999-03-02
NO973922D0 (no) 1997-08-26
HUP9801201A2 (hu) 2000-05-28
GEP20002188B (en) 2000-07-25

Similar Documents

Publication Publication Date Title
MY121225A (en) Taxoids, their preparation and pharmaceutical compositions containing them
MX9804688A (es) Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen.
HUT73134A (en) Novel taxoids, preparation thereof and pharmaceutical compositions containing same
CA2105503A1 (en) Carboxanilides, their preparation and compositions containing them for controlling harmful fungi
GR3023162T3 (en) Novel taxoids, preparation thereof and pharmaceutical compositions containing same
YU38398A (sh) Novi taksoidi, njihovo dobivanje i farmaceutske smeše koje ih sadrže
MX9707427A (es) Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen.
AU3809195A (en) Novel taxoids,their preparation and pharmaceutical compositions containing them
NO943371D0 (no) Fremgangsmåte for fremstilling av taxanderivater
TW363968B (en) Taxoids, their preparation and pharmaceutical compositions containing them
AU2741895A (en) Taxoids, preparation and pharmaceutical compositions containing them
MX9606061A (es) Taxoides , su preparacion y las composiciones farmaceuticas que los contienen.
MX9606227A (es) Taxoides novedosos su preparacion y las composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
FG Grant or registration
HC Change of company name or juridical status

Owner name: UPONOR INNOVATION AB

GD Licence granted